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Patent Searching and Data


Title:
METALLOCENES AS SIGNAL-TRANSDUCER FOR DETECTION OF CHEMICAL OR BIOLOGICAL EVENTS
Document Type and Number:
WIPO Patent Application WO2001092277
Kind Code:
A8
Abstract:
The invention provides compositions, kits, methods, and species that include electroactive entities which can serve as signaling entities in chemical and/or biochemical assays. The electroactive species can be metallocenes, such as ferrocenes, including substituents that affect the oxidation/reduction potential (redox potential) of the species. By controlling the redox potential of the species, multiple species can be used in a single assay, each species having a different redox potential, for simultaneous signaling of different binding events. Additionally, species having redox potentials lower than 490mV can be provided, allowing signaling within a potential range easily detectable in the presence of biological fluids.

Inventors:
BAMDAD CYNTHIA C (US)
BAMDAD R SHOSHANA (US)
FRID MICHAEL (US)
Application Number:
PCT/US2001/040801
Publication Date:
June 29, 2006
Filing Date:
May 25, 2001
Export Citation:
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Assignee:
MINERVA BIOTECHNOLOGIES CORP (US)
BAMDAD CYNTHIA C (US)
BAMDAD R SHOSHANA (US)
FRID MICHAEL (US)
International Classes:
C07F17/02; G01N27/48; C07D213/32; G01N27/416; G01N33/58
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