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Title:
METHOD FOR DETERMINING FACTOR OF CHEMICAL SUBSTANCE INFLUENCING ENDOCRINE SYSTEM
Document Type and Number:
WIPO Patent Application WO/2021/193097
Kind Code:
A1
Abstract:
The present invention provides a method for determining a factor of a chemical substance influencing the endocrine system in an organism, wherein the method includes (1) a step in which the expression amount of a gene serving as a marker and/or the amount of an endogenous metabolite serving as a marker in samples collected from a subject not brought into contact with the chemical substance and from a subject brought into contact with the chemical substance are measured, and (2) a step in which the expression amount of the gene and/or the amount of the endogenous metabolite measured in step (1) are subsequently analyzed and it is determined whether the chemical substance is a factor influencing the endocrine system as an endocrine disruptor or a factor influencing the endocrine system as stress.

Inventors:
SHIMIZU TAKAKO (JP)
YAMADA FUMIHIRO (JP)
KAWAI SHUN (JP)
Application Number:
PCT/JP2021/009779
Publication Date:
September 30, 2021
Filing Date:
March 11, 2021
Export Citation:
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Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C12N15/12; C12N15/53; C12Q1/68; G01N33/68
Domestic Patent References:
WO2000026404A12000-05-11
Foreign References:
JP2002355079A2002-12-10
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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