Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR DIAGNOSING MICROSATELLITE INSTABILITY USING COEFFICIENT OF VARIATION OF SEQUENCE LENGTHS IN MICROSATELLITE LOCI
Document Type and Number:
WIPO Patent Application WO/2022/124575
Kind Code:
A1
Abstract:
The present application provides a method for diagnosing microsatellite instability using a coefficient of variation of sequence lengths in microsatellite loci, comprising the steps of: searching microsatellite loci; selecting target microsatellite loci; detecting aligned sequences in single sample microsatellite loci; selecting sequences containing a microsatellite from among the sequences detected in each locus; calculating the composition and length of the microsatellite in the selected sequences; calculating a coefficient of variation (CV) for the lengths of the microsatellites detected in each microsatellite locus; and diagnosing microsatellite instability using the calculated coefficient of variation.

Inventors:
PARK SEUNG GU (KR)
KIM DONG HA (KR)
SEO SUNG HYUN (KR)
Application Number:
PCT/KR2021/015670
Publication Date:
June 16, 2022
Filing Date:
November 02, 2021
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
DXOME CO LTD (KR)
International Classes:
C12Q1/6827
Domestic Patent References:
WO2020047378A12020-03-05
WO2019074963A12019-04-18
WO2020002621A22020-01-02
Foreign References:
KR20200015913A2020-02-13
KR20170037095A2017-04-04
Attorney, Agent or Firm:
MAPS INTELLECTUAL PROPERTY LAW FIRM (KR)
Download PDF: