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Title:
METHOD FOR EVALUATING TEST SAMPLE
Document Type and Number:
WIPO Patent Application WO/2019/177099
Kind Code:
A1
Abstract:
Provided is a method for evaluating a test sample, said method making it easy to evaluate whether a test sample has the effect of suppressing cytokine production in skin cells, wherein the cytokine production suppressing effect of the test sample is evaluated on the basis of a physiological event triggered by the test sample through TRPM4 in TRPM4-expressing cells.

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Inventors:
SAITO KAORI (JP)
FUJITA FUMITAKA (JP)
OKADA FUMIHIRO (JP)
ISHII KEN (JP)
Application Number:
PCT/JP2019/010547
Publication Date:
September 19, 2019
Filing Date:
March 14, 2019
Export Citation:
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Assignee:
MANDOM CORP (JP)
NAT INST BIOMEDICAL INNOVATION HEALTH & NUTRITION (JP)
International Classes:
C12Q1/6809; A61K8/26; A61K33/06; A61P17/00; A61P17/10; A61P29/00; A61P43/00; A61Q19/00; G01N33/53; C07D417/10; C07J43/00; C12N15/19
Domestic Patent References:
WO2006070860A12006-07-06
WO2005042779A12005-05-12
WO2008080983A12008-07-10
Foreign References:
JP2008211985A2008-09-18
JP2015035061A2015-02-19
US20170035802A12017-02-09
JP2008537029A2008-09-11
JP2014129383A2014-07-10
Other References:
TSUJINAKA, YASUNOBU, NIPPON RINSHO (SEPARATE VOLUME): SYNDROME SERIES 12 FOR NEW AREAS - GASTROINTESTINAL SYNDROME, 2009, pages 857 - 860
Attorney, Agent or Firm:
AKAMATSU Yoshihiro (JP)
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