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Title:
METHOD FOR INDUCING HIBERNATION-LIKE STATE AND DEVICE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/066053
Kind Code:
A1
Abstract:
The present invention provides a method for inducing a hibernation-like state and a device therefor. This method is a chemical and physical method for reducing a theoretical set temperature for the body temperature of a subject and/or a feedback gain of heat production in the subject or for inducing a hibernation-like state in the subject, the method comprising applying an excitatory stimulation to a pyroglutamylated RFamide peptide (QRFP) producing-neuron. This device is used to perform the method.

Inventors:
SAKURAI TAKESHI (JP)
TAKAHASHI TORU (JP)
SUNAGAWA GENSHIRO (JP)
Application Number:
PCT/JP2020/037268
Publication Date:
April 08, 2021
Filing Date:
September 30, 2020
Export Citation:
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Assignee:
UNIV TSUKUBA (JP)
RIKEN (JP)
International Classes:
A61M21/02; A01K67/00; C12Q1/02; G01N33/50
Domestic Patent References:
WO2017195901A12017-11-16
WO2019177142A12019-09-19
Foreign References:
JPH07250837A1995-10-03
US20160144185A12016-05-26
JP2012508635A2012-04-12
US20140039450A12014-02-06
US20150238513A12015-08-27
US20070048731A12007-03-01
JP2014500716A2014-01-16
US20040102368A12004-05-27
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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