Title:
METHOD, KIT, AND COMPOSITE MEMBRANE FOR EX VIVO EXPANSION OF CIRCULATING TUMOR CELLS, PREPARATION METHOD FOR COMPOSITE MEMBRANE, MEDICATION TEST METHOD, AND CRYOPRESERVATION SOLUTION
Document Type and Number:
WIPO Patent Application WO/2021/088902
Kind Code:
A1
Abstract:
A composite membrane for ex vivo expansion of circulating tumor cells and a preparation method for the composite membrane, a kit and method for ex vivo expansion of circulating tumor cells, a medication effect test method, and a cryopreservation solution for cryopreserving expanded circulating tumor cells. The preparation method comprises: mixing one or more particles and a solvent to form a mixed solution, wherein the one or more particles are selected from a group consisting of metal particles, metal oxide particles, silicon oxide particles, and combinations thereof; placing the mixed solution on a substrate to form a particle layer; adding a medium material to the particle layer, wherein the medium material is selected from a group consisting of: styrene and derivatives thereof, polyester monomers, silicon oxides, and combinations thereof; and polymerizing the medium material to form a medium layer to fix the particle layer on the substrate. The composite membrane can effectively increase the number of circulating tumor cells expanded.
Inventors:
CHEN PO-HAN (CN)
HSU WEI-HSIN (CN)
WU SHIH-PEI (CN)
HSU WEI-HSIN (CN)
WU SHIH-PEI (CN)
Application Number:
PCT/CN2020/126634
Publication Date:
May 14, 2021
Filing Date:
November 05, 2020
Export Citation:
Assignee:
CANCER FREE BIOTECH LTD (CN)
International Classes:
C12M3/00; C12N5/09; C40B30/06
Foreign References:
| TW201942351A | 2019-11-01 | |||
| US20140154689A1 | 2014-06-05 | |||
| CN108872182A | 2018-11-23 | |||
| CN108531455A | 2018-09-14 | |||
| CN1871517A | 2006-11-29 | |||
| CN107112302A | 2017-08-29 |
Attorney, Agent or Firm:
SHENZHEN JINGZHI INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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