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Title:
METHOD FOR MANUFACTURING BLENDED FILAMENT YARN FOR CELL CULTURE SUPPORT, BLENDED FILAMENT YARN FOR CELL CULTURE SUPPORT REALIZED THERETHROUGH, AND FABRIC COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2019/013533
Kind Code:
A2
Abstract:
Provided is a method for manufacturing a blended filament yarn for a cell culture support. The method for manufacturing a blended filament yarn according to one embodiment of the present invention is performed by comprising the steps of: (1) preparing a first yarn having at least one of a first motif and a first motif conjugate having an amino acid sequence in which a first amino acid sequence motif is repeated at least twice, and a second yarn having at least one of a second motif, which is different from the first motif, and a second motif conjugate having an amino acid sequence in which a second amino acid sequence motif is repeated at least twice, respectively; and (2) plying the prepared first yarn and second yarn. According to this, different motifs are provided in a unitary blended filament yarn, and the blended filament yarn is very suitable for fully expressing each function of the motifs. Also, such a unitary blended filament yarn may make it possible to implement a micro environment in which the steps of attachment, migration, proliferation, and differentiation of cultured cells can take place continuously. Furthermore, it is possible to culture cell aggregates formed of cells with the same differentiation step, and at the same time to culture multiple cell aggregates with different differentiation steps through a unitary blended filament yarn. In addition, it is possible to three-dimensionally grow the cultured cells to be more suitable for application for in vitro experimental models or implantation in animal bodies, and thus the present invention may be widely applied to various products used in the field of cell culturing or tissue engineering such as a bioreactor, a cell culture container, an implantation kit, and the like.

Inventors:
JANG SEON HO (KR)
KOO SONG HEE (KR)
SEO IN YONG (KR)
LEE SEOUNG HOON (KR)
KIM CHAN (KR)
PARK HEE SUNG (KR)
Application Number:
PCT/KR2018/007822
Publication Date:
January 17, 2019
Filing Date:
July 10, 2018
Export Citation:
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Assignee:
AMOLIFESCIENCE CO LTD (KR)
International Classes:
D02G3/44; A61L27/38; C12N5/00; D02G3/04; D03D1/00; D03D15/00
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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