Title:
METHOD FOR MANUFACTURING DNA-EDITED EUKARYOTIC CELL, AND KIT USED IN METHOD
Document Type and Number:
WIPO Patent Application WO/2018/225858
Kind Code:
A1
Abstract:
Through the present invention, the CRISPR-Cas3 system is successfully established in a eukaryotic cell.
Inventors:
MASHIMO TOMOJI (JP)
TAKEDA JUNJI (JP)
MORISAKA HIROYUKI (JP)
YOSHIMI KAZUTO (JP)
TAKEDA JUNJI (JP)
MORISAKA HIROYUKI (JP)
YOSHIMI KAZUTO (JP)
Application Number:
PCT/JP2018/022066
Publication Date:
December 13, 2018
Filing Date:
June 08, 2018
Export Citation:
Assignee:
UNIV OSAKA (JP)
International Classes:
C12N15/09; A01H1/00; A01K67/027; C12N5/10; C12N15/113
Domestic Patent References:
| WO2017066497A2 | 2017-04-20 | |||
| WO2017043573A1 | 2017-03-16 | |||
| WO2017219033A1 | 2017-12-21 |
Foreign References:
| JP2015503535A | 2015-02-02 | |||
| JP2017512481A | 2017-05-25 | |||
| CN107557378A | 2018-01-09 | |||
| CN107557373A | 2018-01-09 | |||
| JP2015503535W | ||||
| JP2017512481W |
Other References:
MORISAKA, H. ET AL.: "Abstrac 490: Genome editing in mammalian cells by cascade and Cas3", J. INVEST, DERMATOL., vol. 137, no. 5, May 2017 (2017-05-01), pages S84, XP055561205
SUZUKI, KELLCHLRO ET AL.: "In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration", NATURE, vol. 540, 16 November 2016 (2016-11-16), pages 144 - 149, XP055414804
MORISAKA, HIROYUKI ET AL.: "P07-20: Genome editing in mammalian cells by Cascade and Cas3", PROGRAMS AND ABSTRACTS OF 42TH ANNUAL ACADEMIC CONFERENCE AND GENERAL CONFERENCE OF THE JAPANESE SOCIETY FOR INVESTIGATE DERMATOLOGY, 2 November 2017 (2017-11-02), pages 232, XP009517845
JINEK M ET AL.: "A Programmable Dual-RNA Guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, no. 6096, 2012, pages 816 - 821, XP055549487, DOI: 10.1126/science.1225829
MULEPATI SBAILEY S: "In Vitro Reconstitution of an Escherichia coli RNA-guided Immune System Reveals Unidirectional, ATP-dependent Degradation of DNA Target", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, no. 31, 2013, pages 22184 - 22192
AHMED A. GOMAA ET AL.: "Programmable Reomoval of Bacterial Strains by Use of Genome Targeting CRISPR-Cas Systems", MBIO.ASM.ORG, vol. 5, no. 1, 2014, pages e00928 - 13
VAN DER OOST J ET AL.: "Unravelling the structural and mechanistic basis of CRISPR-Cas systems", NATURE REVIEWS MICROBIOLOGYM, vol. 12, no. 7, 2014, pages 479 - 492, XP055619310, DOI: 10.1038/nrmicro3279
JACKSON RN ET AL.: "Fitting CRISPR-associated Cas3 into the Helicase Family Tree", CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 24, 2014, pages 106 - 114
MING LI ET AL., NUCLEIC ACIDS RES., vol. 45, no. 8, 5 May 2017 (2017-05-05), pages 4642 - 4654
WU J ET AL.: "The Intracellular Mobility of Nuclear Import Receptors and NLS Cargoes", BIOPHYSICAL JOURNAL, vol. 96, no. 9, 2009, pages 3840 - 3849
ALTSCHUL SF: "Basic local alignment search tool", JOURNAL OF MOLECULAR BIOLOGY, vol. 215, no. 3, 1990, pages 403 - 410, XP002949123, DOI: 10.1006/jmbi.1990.9999
JOSEPH SAMBROOKDAVID W. RUSSELL: "Molecular cloning: a laboratory manual 3rd Ed.", 2001, COLD SPRING HARBOR LABORATORY PRESS
NISHIDA K. ET AL.: "Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems", SCIENCE, 2016
LEONARD G. DAVIS ET AL.: "Basic methods in molecular biology", 1986, ELSEVIER
NAGY A. ET AL.: "Manipulating the Mouse Embryo", 2003, COLD SPRING HARBOUR LABORATORY PRESS
TABEI YUTAKA, KAGAKU-DOJIN, 2012, pages 340 - 347
SAKUMA T ET AL.: "Efficient TALEN construction and evaluation methods for human cell and animal applications", GENES TO CELLS, vol. 18, no. 4, 2013, pages 315 - 326
SUZUKI K ET AL.: "In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration", NATURE, vol. 540, no. 7631, 2016, pages 144 - 149, XP055414804, DOI: 10.1038/nature20565
LEENAY, R. T ET AL., MOL. CELL, vol. 62, 2016, pages 137 - 147
JUNG ET AL., MOL. CELL., 2017
JUNG ET AL., CELL, vol. 170, 2017, pages 35 - 47
See also references of EP 3636753A4
SUZUKI, KELLCHLRO ET AL.: "In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration", NATURE, vol. 540, 16 November 2016 (2016-11-16), pages 144 - 149, XP055414804
MORISAKA, HIROYUKI ET AL.: "P07-20: Genome editing in mammalian cells by Cascade and Cas3", PROGRAMS AND ABSTRACTS OF 42TH ANNUAL ACADEMIC CONFERENCE AND GENERAL CONFERENCE OF THE JAPANESE SOCIETY FOR INVESTIGATE DERMATOLOGY, 2 November 2017 (2017-11-02), pages 232, XP009517845
JINEK M ET AL.: "A Programmable Dual-RNA Guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, no. 6096, 2012, pages 816 - 821, XP055549487, DOI: 10.1126/science.1225829
MULEPATI SBAILEY S: "In Vitro Reconstitution of an Escherichia coli RNA-guided Immune System Reveals Unidirectional, ATP-dependent Degradation of DNA Target", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 288, no. 31, 2013, pages 22184 - 22192
AHMED A. GOMAA ET AL.: "Programmable Reomoval of Bacterial Strains by Use of Genome Targeting CRISPR-Cas Systems", MBIO.ASM.ORG, vol. 5, no. 1, 2014, pages e00928 - 13
VAN DER OOST J ET AL.: "Unravelling the structural and mechanistic basis of CRISPR-Cas systems", NATURE REVIEWS MICROBIOLOGYM, vol. 12, no. 7, 2014, pages 479 - 492, XP055619310, DOI: 10.1038/nrmicro3279
JACKSON RN ET AL.: "Fitting CRISPR-associated Cas3 into the Helicase Family Tree", CURRENT OPINION IN STRUCTURAL BIOLOGY, vol. 24, 2014, pages 106 - 114
MING LI ET AL., NUCLEIC ACIDS RES., vol. 45, no. 8, 5 May 2017 (2017-05-05), pages 4642 - 4654
WU J ET AL.: "The Intracellular Mobility of Nuclear Import Receptors and NLS Cargoes", BIOPHYSICAL JOURNAL, vol. 96, no. 9, 2009, pages 3840 - 3849
ALTSCHUL SF: "Basic local alignment search tool", JOURNAL OF MOLECULAR BIOLOGY, vol. 215, no. 3, 1990, pages 403 - 410, XP002949123, DOI: 10.1006/jmbi.1990.9999
JOSEPH SAMBROOKDAVID W. RUSSELL: "Molecular cloning: a laboratory manual 3rd Ed.", 2001, COLD SPRING HARBOR LABORATORY PRESS
NISHIDA K. ET AL.: "Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems", SCIENCE, 2016
LEONARD G. DAVIS ET AL.: "Basic methods in molecular biology", 1986, ELSEVIER
NAGY A. ET AL.: "Manipulating the Mouse Embryo", 2003, COLD SPRING HARBOUR LABORATORY PRESS
TABEI YUTAKA, KAGAKU-DOJIN, 2012, pages 340 - 347
SAKUMA T ET AL.: "Efficient TALEN construction and evaluation methods for human cell and animal applications", GENES TO CELLS, vol. 18, no. 4, 2013, pages 315 - 326
SUZUKI K ET AL.: "In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration", NATURE, vol. 540, no. 7631, 2016, pages 144 - 149, XP055414804, DOI: 10.1038/nature20565
LEENAY, R. T ET AL., MOL. CELL, vol. 62, 2016, pages 137 - 147
JUNG ET AL., MOL. CELL., 2017
JUNG ET AL., CELL, vol. 170, 2017, pages 35 - 47
See also references of EP 3636753A4
Attorney, Agent or Firm:
CENTCREST IP ATTORNEYS (JP)
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