Title:
METHOD FOR MEASURING VIRAL NUCLEIC ACID, DEVICE FOR MEASURING VIRAL NUCLEIC ACID, PROGRAM, SENSOR, LAYERED ELECTRODE, AND SUBSTRATE WITH ELECTRODE
Document Type and Number:
WIPO Patent Application WO/2022/080023
Kind Code:
A1
Abstract:
The method for measuring viral nucleic acid according to the present invention comprises: bringing a specimen containing a virus (31) into contact with a combined electrode including at least a counter electrode (25) and a layered electrode (22) having a boron-doped diamond electrode (28) and a copper-coating layer (29) disposed on the electrode; applying a constant potential to the layered electrode to cause elution of the copper-coating layer, to generate copper ions, to cause the virus (41) to release viral nucleic acid (33), and to expose the boron-doped diamond electrode to the specimen; and sweeping the potential of the boron-doped diamond electrode and measuring an electrochemical response derived from the viral nucleic acid. The method enables quick measurement of viral nucleic acid in a specimen collected from aerosol or the like.
Inventors:
OKAMOTO AKIHIRO (JP)
Application Number:
PCT/JP2021/031778
Publication Date:
April 21, 2022
Filing Date:
August 30, 2021
Export Citation:
Assignee:
NAT INST MATERIALS SCIENCE (JP)
International Classes:
C12M1/00; C12N15/10; C12Q1/02; C12Q1/68; G01N27/28; G01N27/30; G01N27/48
Foreign References:
JP2002310977A | 2002-10-23 | |||
JP2014517281A | 2014-07-17 | |||
JP2007163224A | 2007-06-28 |
Other References:
WARNES SARAH L., SUMMERSGILL EMMA N., KEEVIL C. WILLIAM: "Inactivation of Murine Norovirus on a Range of Copper Alloy Surfaces Is Accompanied by Loss of Capsid Integrity", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 81, no. 3, 1 February 2015 (2015-02-01), US , pages 1085 - 1091, XP055922234, ISSN: 0099-2240, DOI: 10.1128/AEM.03280-14
Attorney, Agent or Firm:
KANEYAMA Yoshinobu et al. (JP)
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