METHOD FOR THE PREPARATION OF CRYSTALLINE TETRAHYDROBENZOTHIEPINES

Title:

METHOD FOR THE PREPARATION OF CRYSTALLINE TETRAHYDROBENZOTHIEPINES

Document Type and Number:

WIPO Patent Application WO2003022804

Kind Code:

A9

Abstract:

Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of single crystals of ASBT inhibitors having high purity and low levels of solvent impurities.

More Like This:

WO/2015/135091	PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS
JP2004511559	3,8-Diazabicyclo [3.2.1] Its use in the treatment of octane and cardiac arrhythmias
JP6815417	New compounds and their pharmacologically acceptable salts

Inventors:

MUDIPALLI PARTHA S (US)
POZZO MARK J (US)
PARK JUNG MIN (US)

Application Number:

PCT/US2002/026877

Publication Date:

December 18, 2003

Filing Date:

August 23, 2002

Export Citation:

Click for automatic bibliography generation Help

Assignee:

SEARLE LLC (US)
MUDIPALLI PARTHA S (US)
POZZO MARK J (US)
PARK JUNG MIN (US)

International Classes:

A61K31/4995; A61P1/16; A61P3/06; A61P43/00; B01D9/02; C07D337/08; C07D487/08; (IPC1-7): C07D409/10; C07D337/08; C07D409/12

Download PDF:

View/Download PDF PDF Help

Previous Patent: COMPOUND HAVING THERMALLY DISSOCIABLE THIOACETAL SKELETON, PRECURSOR THEREFOR, CURED ARTICLE, AND CO...

Next Patent: HETEROCYCLE SUBSTITUTED PURINES AS ANTIPROLIFERATIVE AGENTS