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Title:
METHOD FOR PREPARATION OF SOYBEAN LEAF HAVING HIGH CONTENT OF ISOFLAVONE DERIVATIVE IN DARK CONDITION AND SOYBEAN LEAF HAVING HIGH CONTENT OF ISOFLAVONE DERIVATIVE PREPARED THEREBY
Document Type and Number:
WIPO Patent Application WO/2021/015583
Kind Code:
A3
Abstract:
The present invention relates to a method for preparation of soybean leaves having a high content of an isoflavone derivative in a dark condition and soybean leaves having a high content of an isoflavone derivative prepared thereby. Specifically, treatment of a soybean plant 20 days to 60 days after seeding with a predetermined concentration of ethylene in a dark condition was found to accumulate higher concentrations of isoflavone derivatives in soybean leaves than treatment with ethephon in a light condition, which requires a high level of energy. Therefore, when used, the method of the present invention can economically and quickly prepare soybean leaves having a very high content of isoflavones, and the soybean leaves having a high content of isoflavone derivatives, an extract of the soybean leaves, and a fraction of the extract can be advantageously used as a food and medicine material against diseases caused by estrogen unbalance and deficient antioxidant activity.

Inventors:
PARK KI HUN (KR)
BAN YEONG JUN (KR)
SONG YEONG HUN (KR)
Application Number:
PCT/KR2020/009766
Publication Date:
March 18, 2021
Filing Date:
July 24, 2020
Export Citation:
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Assignee:
NAT UNIV GYEONGSANG IACF (KR)
International Classes:
A01H3/02; A01H3/04; A01H5/12; A01H6/54; A23F3/14; A23L33/105; A61K8/9789; A61K31/352; A61K36/48; C07D311/36
Foreign References:
KR101451298B12014-10-16
KR20050104097A2005-11-02
CN106047889A2016-10-26
Other References:
KONG SEUNG-HEON, LEE DEUK-YEONG, BAE JI-YEON, SONG YOUNG-HOON, PARK KI-HUN, JANG KI-CHANG, KIM JIN-HYO: "Effect of Postharvest Treatment of Ethylene or Light on Total Flavonoid in Soybean Leaf", THE KOREAN JOURNAL OF PESTICIDE SCIENCE, vol. 22, no. 2, 30 June 2018 (2018-06-30), pages 153 - 157, XP055790135, ISSN: 1226-6183, DOI: 10.7585/kjps.2018.22.2.153
REVIEW, MARTINS AGUIAR PAULA, DE ANTONY, BARBOSA PAULA: "African Journal of Pharmacy and Pharmacology Use of soy isoflavones on hormone replacement therapy during climacteric", AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 8, no. 42, 15 November 2014 (2014-11-15), pages 1071 - 1078, XP055790133, DOI: 10.5897/AJPP2014.4134
KIRAKOSYAN ARA, KAUFMAN PETER, NELSON RANDALL L., KASPERBAUER MICHAEL J., DUKE JAMES A., SEYMOUR ELISABETH, CHANG SOO CHUL, WARBER: "Isoflavone Levels in Five Soybean ( Glycine max ) Genotypes Are Altered by Phytochrome-Mediated Light Treatments", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, AMERICAN CHEMICAL SOCIETY, BOOKS AND JOURNALS DIVISION|, US, vol. 54, no. 1, 1 January 2006 (2006-01-01), US, pages 54 - 58, XP055790128, ISSN: 0021-8561, DOI: 10.1021/jf052458w
YUK HEUNG JOO, SONG YEONG HUN, CURTIS-LONG MARCUS J., KIM DAE WOOK, WOO SU GYEONG, LEE YONG BOK, UDDIN ZIA, KIM CHA YOUNG, PARK KI: "Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean ( Glycine max ) Leaves", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, AMERICAN CHEMICAL SOCIETY, BOOKS AND JOURNALS DIVISION|, US, vol. 64, no. 39, 5 October 2016 (2016-10-05), US, pages 7315 - 7324, XP055790126, ISSN: 0021-8561, DOI: 10.1021/acs.jafc.6b02543
BAN YEONG JUN, YEONG HUN SONG, JEONG YOON KIM, AIZHAMAL BAISEITOVA, KI WON LEE, KWANG DONG KIM, KI HUN PARK: "Comparative investigation on metabolites changes in soy- bean leaves by ethylene and activation of collagen synthesis", INDUSTRIAL CROPS & PRODUCTS, vol. 154, XP055790124
Attorney, Agent or Firm:
LEE, Won Hee (KR)
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