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Title:
METHOD FOR PRODUCING AMINOGLYCOSIDE ANTIBIOTIC
Document Type and Number:
WIPO Patent Application WO/2017/078097
Kind Code:
A1
Abstract:
Provided is a method for stably producing (2S)-2-hydroxydibekacin, said method being characterized by the use of 2-hydroxykanamycin C or 2-hydroxykanamycin B as a starting material or synthetic intermediate.

Inventors:
TAKAHASHI YOSHIAKI (JP)
UMEMURA EIJIRO (JP)
Application Number:
PCT/JP2016/082667
Publication Date:
May 11, 2017
Filing Date:
November 02, 2016
Export Citation:
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Assignee:
MEIJI SEIKA PHARMA CO LTD (JP)
MICROBIAL CHEM RES FOUND (JP)
International Classes:
C07H15/234; A61P31/04; A61K31/7036; C07B51/00; C07B61/00
Domestic Patent References:
WO2007142150A12007-12-13
WO2009069800A12009-06-04
Foreign References:
JPS608299A1985-01-17
CN101575354A2009-11-11
Other References:
YONETA,T. ET AL.: "An improved synthesis of 3', 4'-dideoxykanamycin B", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 52, no. 4, 1979, pages 1131 - 1134, XP055379556
RAKHIT,S. ET AL.: "Facile synthesis of purpurosamine C, a component of the antibiotic gentamicin Cla", JOURNAL OF CARBOHYDRATES, NUCLEOSIDES, NUCLEOTIDES, vol. 2, no. 2, 1975, pages 153 - 157
Attorney, Agent or Firm:
NAGAI Hiroshi et al. (JP)
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