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Title:
METHOD FOR PRODUCING BETA-L-2'DEOXY-THYMIDINE
Document Type and Number:
WIPO Patent Application WO2003087118
Kind Code:
A3
Abstract:
The invention relates to a novel method, essentially having four stages, for producing beta-L-2'-deoxy-thymidine with L-arabinose as the starting material. The inventive method is particularly useful for the large-scale production of beta-L-2'-deoxy-thymidine.

Inventors:
KLINGLER FRANZ DIETRICH (DE)
KREYE PAUL (DE)
BAUMGARTEN WOLFGANG (DE)
Application Number:
PCT/EP2003/003591
Publication Date:
February 05, 2004
Filing Date:
April 07, 2003
Export Citation:
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Assignee:
BOEHRINGER INGELHEIM PHARMA (DE)
KLINGLER FRANZ DIETRICH (DE)
KREYE PAUL (DE)
BAUMGARTEN WOLFGANG (DE)
International Classes:
C07H1/00; C07H9/06; C07H19/06; (IPC1-7): C07H19/06; C07H9/06; C07H1/00
Domestic Patent References:
WO2001034618A22001-05-17
WO2002044194A12002-06-06
Other References:
HOLY A: "Nucleic acid components and their analogues. CLIII. Preparation of 2'-deoxy-L-ribonucleosides of the pyrimidine series", COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, ACADEMIC PRESS, LONDON, GB, vol. 37, 1972, pages 4072 - 4087, XP002164643, ISSN: 0010-0765
I.A. MIKHAILOPULO, G.G. SIVETS: "Synthesis of peracylated derivatives of L-ribofuranose from D-ribose and their use for the preparation of beta-L-ribonucleosides", COLLECTION SYMPOSIUM SERIES, vol. 2, 1999, pages 53 - 56, XP008022497
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