Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR PRODUCING EPIRUBICIN AND NOVEL PRODUCTION INTERMEDIATE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2016/159092
Kind Code:
A1
Abstract:
In the present invention, an organic acid salt of 4'-epidaunorubicin or a hydrate or a solvate thereof is used as a novel production intermediate, whereby it is possible to efficiently remove 13-dihydroepidaunorubicin and 4'-epifeudomycin, which are typical impurities that may be present in the starting-material 4'-epidaunorubicin, and to produce highly pure epirubicin.

Inventors:
MORI KENICHIRO (JP)
UMEZU TAKUTO (JP)
MARUYAMA TAKAHISA (JP)
SHIOKAWA SOJIRO (JP)
Application Number:
PCT/JP2016/060409
Publication Date:
October 06, 2016
Filing Date:
March 30, 2016
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
MEIJI SEIKA PHARMA CO LTD (JP)
International Classes:
C07H15/252
Domestic Patent References:
WO2006096665A12006-09-14
WO2007076345A22007-07-05
WO2009035107A12009-03-19
WO2011145211A12011-11-24
Foreign References:
JPH0776515A1995-03-20
JP2007261976A2007-10-11
JP2010525828A2010-07-29
JPS5687598A1981-07-16
Other References:
See also references of EP 3279206A4
Attorney, Agent or Firm:
NAGAI Hiroshi et al. (JP)
Hiroyuki Nagai (JP)
Download PDF: