Title:
METHOD FOR PRODUCING NITROGEN-CONTAINING FUSED RING COMPOUND
Document Type and Number:
WIPO Patent Application WO/2007/139002
Kind Code:
A1
Abstract:
It is intended to provide a method for producing an excellent compound effective
in the treatment, prevention or the like of pathological conditions associated
with uric acid such as hyperuricemia, tophus, acute gouty arthritis, chronic
gouty arthritis, gouty nephropathy, urolithiasis, renal dysfunction, coronary
artery disease and ischemic heart disease and a method for purifying the same.
By reacting a compound represented by the general formula [3] or a salt thereof
and a compound represented by the general formula [4] or a reactive derivative
thereof, a compound represented by the general formula [2] or a pharmaceutically
acceptable salt thereof can be produced. Further, the crystallization of the
compound represented by the general formula [2] can be conduced with an industrially
excellent workability and a high quality crystal of the compound represented
by the general formula [2] can be obtained. [3] [4] [2] (In the
formulae, each symbol is as described in the specification.)
Inventors:
HIRATA KAZUYUKI (JP)
OGAWA NAOKI (JP)
SHINAGAWA YUKO (JP)
KIGUCHI TOSHIHIRO (JP)
INOUE TERUHIKO (JP)
KOMEDA YASUKI (JP)
YAMASHITA ICHIRO (JP)
KAMIYA YUKIHIRO (JP)
OGAWA NAOKI (JP)
SHINAGAWA YUKO (JP)
KIGUCHI TOSHIHIRO (JP)
INOUE TERUHIKO (JP)
KOMEDA YASUKI (JP)
YAMASHITA ICHIRO (JP)
KAMIYA YUKIHIRO (JP)
Application Number:
PCT/JP2007/060678
Publication Date:
December 06, 2007
Filing Date:
May 25, 2007
Export Citation:
Assignee:
JAPAN TOBACCO INC (JP)
HIRATA KAZUYUKI (JP)
OGAWA NAOKI (JP)
SHINAGAWA YUKO (JP)
KIGUCHI TOSHIHIRO (JP)
INOUE TERUHIKO (JP)
KOMEDA YASUKI (JP)
YAMASHITA ICHIRO (JP)
KAMIYA YUKIHIRO (JP)
HIRATA KAZUYUKI (JP)
OGAWA NAOKI (JP)
SHINAGAWA YUKO (JP)
KIGUCHI TOSHIHIRO (JP)
INOUE TERUHIKO (JP)
KOMEDA YASUKI (JP)
YAMASHITA ICHIRO (JP)
KAMIYA YUKIHIRO (JP)
International Classes:
C07D209/12; C07D215/08; C07D223/16; C07D241/42; C07D243/14; C07D265/34; C07D265/36; C07D265/38; C07D267/14; C07D279/16; C07D498/04; A61K31/404; A61K31/47; A61K31/498; A61K31/538; A61K31/5383; A61K31/5415; A61K31/55; A61K31/5513; A61K31/553; A61P3/06; A61P3/10; A61P9/12; A61P13/02
Domestic Patent References:
WO2006057460A1 | 2006-06-01 |
Foreign References:
JPH04321669A | 1992-11-11 | |||
JPH08301848A | 1996-11-19 |
Attorney, Agent or Firm:
TAKASHIMA, Hajime (1-1 Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka 44, JP)
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