Title:
METHOD FOR PRODUCING PHENYL PROPANE-BASED COMPOUND INTERMEDIATE USING ENZYMES
Document Type and Number:
WIPO Patent Application WO/2015/119281
Kind Code:
A1
Abstract:
The objective of the present invention is to provide a method which, relative to prior methods, specifically and efficiently produces a glutathione-added phenyl propane-based compound, which is an intermediate of a phenyl propane-based compound, from a carbonyl phenyl propane-based compound, said intermediate to be utilized when producing a compound having a phenyl propane structure from natural biomass containing lignins by exerting enzyme action. The abovementioned objective is solved by glutathione S-transferase derived from micro-organisms of the genus Novosphingobium, and a method for producing a glutathione-added phenyl propane-based compound, said method including a step for obtaining the glutathione-added phenyl propane-based compound by exerting the action of said enzyme on a carbonyl phenyl propane-based compound in the presence of reduced glutathione.
Inventors:
OHTA YUKARI (JP)
HATADA YUJI (JP)
HASEGAWA RYOICHI (JP)
HATADA YUJI (JP)
HASEGAWA RYOICHI (JP)
Application Number:
PCT/JP2015/053552
Publication Date:
August 13, 2015
Filing Date:
February 09, 2015
Export Citation:
Assignee:
JAPAN AGENCY MARINE EARTH SCI (JP)
International Classes:
C12P11/00; C12N9/10; C12N15/09; C12R1/01
Foreign References:
| JP2006230255A | 2006-09-07 | |||
| JP2012130326A | 2012-07-12 | |||
| JP2002034557A | 2002-02-05 |
Other References:
GALL, D.L. ET AL.: "Stereochemical Features of Glutathione-dependent Enzymes in the Sphingobium sp. Strain SYK-6 beta-Aryl Etherase Pathway", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 289, no. 12, pages 8656 - 8667, XP055218446
AKIHITO OCHIAI: "Sphingomonas wa Yutosei", JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, vol. 89, no. 10, October 2011 (2011-10-01), Japan, pages 614
MASAI, E. ET AL.: "Complete Genome Sequence of Sphingobium sp. Strain SYK-6, a Degrader of Lignin-Derived Biaryls and Monoaryls", JOURNAL OF BACTERIOLOGY, vol. 194, no. 2, January 2012 (2012-01-01), pages 534 - 535, XP055218448
TAKAO KISHIMOTO: "Synthesis of Lignin Model Compounds and Their Application to Wood Research", JOURNAL OF WOOD SCIENCE, vol. 55, no. 4, 2009, pages 187 - 197, XP055218459
YUKARI OTA ET AL.: "Shinkai Chinboku kara Tanri shita Bacteria no Bunruigakuteki Ichi to Hokozoku Monomer Taisha", DAI 57 KAI PROCEEDINGS OF THE LIGNIN SYMPOSIUM, 1 October 2012 (2012-10-01), pages 128
GALL, D.L. ET AL.: "A Group of Sequence-Related Sphingomonad Enzymes Catalyzes Cleavage of beta- Aryl Ether Linkages in Lignin beta-Guaiacyl and beta- Syringyl Ether Dimers", ENVIRON. SCI. TECHNOL., vol. 48, September 2014 (2014-09-01), pages 12454 - 12463, XP055218461
KAGAMI IIDA ET AL.: "Shinkai Chinboku kara Tanri shita Novosphingobium-zoku Saikin no 2 Ryotai Lignin Model Kagobutsu beta-0-4 Ketsugo Kangenteki Kairetsu Kosogun no Kaiseki", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
KANAKO KUROSAWA ET AL.: "Shinkai Yurai Novosphingobium-zoku Saikin o Mochiita Biomass kara no Hokozoku Monomer Seisan", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
YUKARI OTA ET AL.: "Shinkai Chinboku kara Tanri shita Biseibutsu ga Seisan suru Lignin Yurai Hokozoku Monomer Genryo to shite no Potential", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
OHTA, Y. ET AL.: "Draft Genome Sequence of Novosphingobium sp. Strain MBES04, Isolated from Sunken Wood from Suruga Bay", GENOME ANNOUNCEMENTS, vol. 3, no. Issue 1, 15 January 2015 (2015-01-15), Japan, pages e01373 - 14, XP055218472
AKIHITO OCHIAI: "Sphingomonas wa Yutosei", JOURNAL OF THE SOCIETY FOR BIOSCIENCE AND BIOENGINEERING, vol. 89, no. 10, October 2011 (2011-10-01), Japan, pages 614
MASAI, E. ET AL.: "Complete Genome Sequence of Sphingobium sp. Strain SYK-6, a Degrader of Lignin-Derived Biaryls and Monoaryls", JOURNAL OF BACTERIOLOGY, vol. 194, no. 2, January 2012 (2012-01-01), pages 534 - 535, XP055218448
TAKAO KISHIMOTO: "Synthesis of Lignin Model Compounds and Their Application to Wood Research", JOURNAL OF WOOD SCIENCE, vol. 55, no. 4, 2009, pages 187 - 197, XP055218459
YUKARI OTA ET AL.: "Shinkai Chinboku kara Tanri shita Bacteria no Bunruigakuteki Ichi to Hokozoku Monomer Taisha", DAI 57 KAI PROCEEDINGS OF THE LIGNIN SYMPOSIUM, 1 October 2012 (2012-10-01), pages 128
GALL, D.L. ET AL.: "A Group of Sequence-Related Sphingomonad Enzymes Catalyzes Cleavage of beta- Aryl Ether Linkages in Lignin beta-Guaiacyl and beta- Syringyl Ether Dimers", ENVIRON. SCI. TECHNOL., vol. 48, September 2014 (2014-09-01), pages 12454 - 12463, XP055218461
KAGAMI IIDA ET AL.: "Shinkai Chinboku kara Tanri shita Novosphingobium-zoku Saikin no 2 Ryotai Lignin Model Kagobutsu beta-0-4 Ketsugo Kangenteki Kairetsu Kosogun no Kaiseki", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
KANAKO KUROSAWA ET AL.: "Shinkai Yurai Novosphingobium-zoku Saikin o Mochiita Biomass kara no Hokozoku Monomer Seisan", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
YUKARI OTA ET AL.: "Shinkai Chinboku kara Tanri shita Biseibutsu ga Seisan suru Lignin Yurai Hokozoku Monomer Genryo to shite no Potential", DAI 64 KAI ABSTRACTS OF THE ANNUAL MEETING OF THE JAPAN WOOD RESEARCH SOCIETY ( CD VER., 3 March 2014 (2014-03-03)
OHTA, Y. ET AL.: "Draft Genome Sequence of Novosphingobium sp. Strain MBES04, Isolated from Sunken Wood from Suruga Bay", GENOME ANNOUNCEMENTS, vol. 3, no. Issue 1, 15 January 2015 (2015-01-15), Japan, pages e01373 - 14, XP055218472
Attorney, Agent or Firm:
MORIMOTO, TOSHIAKI (JP)
Toshiaki Morimoto (JP)
Toshiaki Morimoto (JP)
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