Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR PRODUCING RADIOACTIVE METAL COMPLEX
Document Type and Number:
WIPO Patent Application WO/2021/033530
Kind Code:
A1
Abstract:
This method for producing a radioactive metal complex comprises a step for reacting a radioactive metal with DOTA or a ligand, which is a derivative of DOTA, in a reaction solution to form a radioactive metal complex. The reaction solution contains water, a buffer, and a water-soluble organic solvent. The radioactive metal is 89Zr or 225Ac. The ligand may have a group linked to a peptide in the structure thereof. It is also preferable that the content of the water-soluble organic solvent contained in the reaction solution be 2-50 vol%. It is also preferable to react the radioactive metal with the ligand in the reaction solution at a temperature of 30-80°C.

Inventors:
IMAI TOMOYUKI (JP)
KIRIU MASATO (JP)
IZAWA AKIHIRO (JP)
Application Number:
PCT/JP2020/029757
Publication Date:
February 25, 2021
Filing Date:
August 04, 2020
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
NIHON MEDIPHYSICS CO LTD (JP)
International Classes:
C07D257/02; C07D403/12; C07D403/14; C07F5/00; C07F7/00
Attorney, Agent or Firm:
SHOWA INTERNATIONAL PATENT FIRM (JP)
Download PDF: