Title:
METHOD FOR PRODUCING TRI-CARBOBENZOXY-ARGININE
Document Type and Number:
WIPO Patent Application WO/2015/146882
Kind Code:
A1
Abstract:
By adding carbobenzoxy chloride and a basic group in a water/organic solvent bilayer system to arginine or an arginine derivative (1) which are represented by belowmentioned formula (1), or a salt of said arginine derivative (1), the arginine or arginine derivative (1) represented by formula (1) or a salt of said arginine derivative (1) is carbobenzoxylated to produce tri-carbobenzoxy-arginine represented by belowmentioned formula (2).
Inventors:
MACHIDA KOJI (JP)
MORI KOHEI (JP)
KISHIMOTO NARUMI (JP)
TAKEDA TOSHIHIRO (JP)
MORI KOHEI (JP)
KISHIMOTO NARUMI (JP)
TAKEDA TOSHIHIRO (JP)
Application Number:
PCT/JP2015/058672
Publication Date:
October 01, 2015
Filing Date:
March 23, 2015
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C07C277/08; C07C279/24
Domestic Patent References:
| WO2003066563A1 | 2003-08-14 |
Foreign References:
| JPH1171335A | 1999-03-16 | |||
| JP2001199943A | 2001-07-24 | |||
| JP2011526910A | 2011-10-20 | |||
| JP2002173457A | 2002-06-21 | |||
| JP2003300926A | 2003-10-21 |
Other References:
JETTEN M. ET AL.: "A one-pot N-protection of L- arginine", TETRAHEDRON LETTERS, vol. 32, no. 42, 1991, pages 6025 - 8, XP055227329, ISSN: 0040-4039
ZERVAS L. ET AL.: "Studies on Arginine peptides. I. Intermediates in the synthesis of N-terminal and C-terminal arginine peptides", J. ORG. CHEM., vol. 22, no. 11, 1957, pages 1515 - 21, XP001074255
ZERVAS L. ET AL.: "Studies on Arginine peptides. I. Intermediates in the synthesis of N-terminal and C-terminal arginine peptides", J. ORG. CHEM., vol. 22, no. 11, 1957, pages 1515 - 21, XP001074255
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
Hisakazu Ueki (JP)
Hisakazu Ueki (JP)
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