Title:
METHOD FOR PRODUCTING THIOLANE SKELETON-TYPE GLYCOCONJUGATE, AND THIOLANE SKELETON-TYPE GLYCOCONJUGATE
Document Type and Number:
WIPO Patent Application WO/2015/125781
Kind Code:
A1
Abstract:
A method for producing a compound represented by general formula (II) via a step for reacting a compound represented by general formula (I) with a sulfur compound, and a compound. In general formulas (I) and (II), R1 represents a hydrogen atom or acyl group, R2 represents a hydrogen atom, fluorine atom, acyloxy group, arylmethyloxy group, allyloxy group, arylmethyloxycarbonyloxy group, or allyloxycarbonyloxy group, R3 represents a hydrogen atom or acyloxy group, R5 represents an alkyl group or aryl group, and X represents a leaving group. However, R3 is an acyloxy group when R2 is a fluorine atom, acyloxy group, arylmethyloxy group, allyloxy group, arylmethyloxycarbonyloxy group, or allyloxycarbonyloxy group.
Inventors:
ITO TAKAYUKI (JP)
WATANABE TORU (JP)
OKADA HIDEKI (JP)
KUNIYOSHI HIDENOBU (JP)
WATANABE TORU (JP)
OKADA HIDEKI (JP)
KUNIYOSHI HIDENOBU (JP)
Application Number:
PCT/JP2015/054305
Publication Date:
August 27, 2015
Filing Date:
February 17, 2015
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C07D333/32; C07H13/08; C07H15/18; C07B53/00
Domestic Patent References:
| WO2014027658A1 | 2014-02-20 |
Foreign References:
| JP2006335737A | 2006-12-14 | |||
| JP2013514260A | 2013-04-25 | |||
| JP2005503358A | 2005-02-03 |
Other References:
BREDENKAMP,M.P. ET AL., TETRAHEDRON LETTERS, vol. 31, no. 19, 1990, pages 2759 - 62, XP055221279
REIST,E.J. ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 33, no. 1, 1968, pages 189 - 92, XP055221284
REIST,E.J. ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 86, no. 24, 1964, pages 5658 - 63, XP055221287
HARTSEL,S.A. ET AL., TETRAHEDRON LETTERS, vol. 39, no. 3/4, 1998, pages 205 - 208, XP004100922
PEJANOVIC,V. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, no. 11, 2003, pages 1849 - 1852, XP055221315
TIWARI,K.N. ET AL., NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, vol. 22, no. 12, 2003, pages 2161 - 2170, XP055221323
REIST,E.J. ET AL., JOURNAL OF ORGANIC CHEMISTRY, vol. 33, no. 1, 1968, pages 189 - 92, XP055221284
REIST,E.J. ET AL., JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 86, no. 24, 1964, pages 5658 - 63, XP055221287
HARTSEL,S.A. ET AL., TETRAHEDRON LETTERS, vol. 39, no. 3/4, 1998, pages 205 - 208, XP004100922
PEJANOVIC,V. ET AL., BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 13, no. 11, 2003, pages 1849 - 1852, XP055221315
TIWARI,K.N. ET AL., NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, vol. 22, no. 12, 2003, pages 2161 - 2170, XP055221323
Attorney, Agent or Firm:
IIDA, Toshizo et al. (JP)
Toshizo Iida (JP)
Toshizo Iida (JP)
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