Title:
METHOD FOR THE PRODUCTION OF MACROLIDES
Document Type and Number:
WIPO Patent Application WO2006087238
Kind Code:
A9
Abstract:
A process for the conversion of 6-11 bridged bicyclic ketolide or erythromycin oximes to 6-11 bridged bicyclic ketolides or erythromycins comprises reacting a 6-11 bridged macrolide with a deoximating agent, preferably an oxidative deoximating agent such as Dess-Martin periodinane. The procedure may comprise deoximation of certain erythromycin A C-9 oxime derivatives with regeneration of the C-9 keto function.
Inventors:
HEGGELUND AUDUN (NO)
Application Number:
PCT/EP2006/001673
Publication Date:
October 05, 2006
Filing Date:
February 21, 2006
Export Citation:
Assignee:
ALPHARMA APS (DK)
HEGGELUND AUDUN (NO)
HEGGELUND AUDUN (NO)
International Classes:
C07H17/08
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