Title:
METHOD AND SYSTEM FOR GENETIC MANIPULATION OF SOUND-SENSITIVE ION CHANNELS
Document Type and Number:
WIPO Patent Application WO/2017/035767
Kind Code:
A1
Abstract:
A method and system for genetic manipulation of sound-sensitive ion channels. The method comprises: acquiring a sound wave (101); focusing the sound wave on endogenous mechanosensitive ion channels of nerve cells to be stimulated, opening the endogenous mechanosensitive ion channels, and/or focusing the sound wave on exogenous mechanosensitive ion channels of the nerve cells to be stimulated, and opening the exogenous mechanosensitive ion channels, to change a membrane potential of the nerve cells (102). This solution implements noninvasive, accurate, and selectively-specific nerve operation and regulation by means of a sound wave.
Inventors:
ZHENG HAIRONG (CN)
NIU LILI (CN)
LIU XIN (CN)
MENG LONG (CN)
QIU WEIBAO (CN)
QIAN MING (CN)
CAI FEIYAN (CN)
XIAO YANG (CN)
WANG CONGZHI (CN)
NIU LILI (CN)
LIU XIN (CN)
MENG LONG (CN)
QIU WEIBAO (CN)
QIAN MING (CN)
CAI FEIYAN (CN)
XIAO YANG (CN)
WANG CONGZHI (CN)
Application Number:
PCT/CN2015/088706
Publication Date:
March 09, 2017
Filing Date:
September 01, 2015
Export Citation:
Assignee:
SHENZHEN INST OF ADV TECH CAS (CN)
International Classes:
A61N7/00
Foreign References:
| US20110092800A1 | 2011-04-21 | |||
| CN103028202A | 2013-04-10 | |||
| CN103432691A | 2013-12-11 | |||
| CN104826243A | 2015-08-12 | |||
| CN104548390A | 2015-04-29 |
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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