Title:
METHOD FOR TREATING CANCER METASTASIS AND COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/130150
Kind Code:
A1
Abstract:
The present invention discloses a method for treating cancer metastasis by using IL-35 antagonist and composition thereof.
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Inventors:
YANG MUH-HWA (CN)
LEE CHIH-CHAN (CN)
LEE CHIH-CHAN (CN)
Application Number:
PCT/CN2018/071957
Publication Date:
July 19, 2018
Filing Date:
January 09, 2018
Export Citation:
Assignee:
UNIV NAT YANG MING (CN)
International Classes:
A61K39/395; A61P35/04
Other References:
HUANG CHONGBIAO: "Tumor derived IL -35 promotes pancreatic tumor cells extravasation and metastasis via inducing ICAM1 expression", DOCTOR DISSERTATION, 15 April 2016 (2016-04-15), pages 1 - 139, XP009515638
FRIEDMAN A ET AL : "THE ROLE OF THE CYTOKINES IL -27 AND IL -35 IN CANCER", MATHEMATICAL BIOSCIENCES AND ENGINEERING, vol. 12, no. 6, 1 December 2015 (2015-12-01), pages 1203 - 1217, XP055613784, ISSN: 1551-0018, DOI: 10.3934/mbe.2015.12.1203
HUANG C ET AL.: "Current Research of the Roles of IL -35 in Tumor Progression", CHINESE JOURNAL OF LUNG CANCER, vol. 19, no. 4, 1 April 2016 (2016-04-01), pages 230 - 235, XP055613785, DOI: 10.3779/j.issn.1009-3419.2016.04.09
EVANS J ET AL.: "Abstract 5139: Adjuvant immunotherapy targeting CSF1R to limit metastatic progression", AACR ANNUAL MEETING, vol. 76, no. 14, 31 July 2016 (2016-07-31), pages 5139 - 5139, XP009515565, DOI: 10.1158/1538-7445.AM2016-5139
FRIEDMAN A ET AL.: "THE ROLE OF THE CYTOKINES IL -27 AND IL -35 IN CANCER", MATHEMATICAL BIOSCIENCES AND ENGINEERING, vol. 12, no. 6, 1 December 2015 (2015-12-01), pages 1203 - 1217, XP055613784, DOI: 10.3934/mbe.2015.12.1203
See also references of EP 3522925A4
FRIEDMAN A ET AL : "THE ROLE OF THE CYTOKINES IL -27 AND IL -35 IN CANCER", MATHEMATICAL BIOSCIENCES AND ENGINEERING, vol. 12, no. 6, 1 December 2015 (2015-12-01), pages 1203 - 1217, XP055613784, ISSN: 1551-0018, DOI: 10.3934/mbe.2015.12.1203
HUANG C ET AL.: "Current Research of the Roles of IL -35 in Tumor Progression", CHINESE JOURNAL OF LUNG CANCER, vol. 19, no. 4, 1 April 2016 (2016-04-01), pages 230 - 235, XP055613785, DOI: 10.3779/j.issn.1009-3419.2016.04.09
EVANS J ET AL.: "Abstract 5139: Adjuvant immunotherapy targeting CSF1R to limit metastatic progression", AACR ANNUAL MEETING, vol. 76, no. 14, 31 July 2016 (2016-07-31), pages 5139 - 5139, XP009515565, DOI: 10.1158/1538-7445.AM2016-5139
FRIEDMAN A ET AL.: "THE ROLE OF THE CYTOKINES IL -27 AND IL -35 IN CANCER", MATHEMATICAL BIOSCIENCES AND ENGINEERING, vol. 12, no. 6, 1 December 2015 (2015-12-01), pages 1203 - 1217, XP055613784, DOI: 10.3934/mbe.2015.12.1203
See also references of EP 3522925A4
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
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