Title:
METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID
Document Type and Number:
WIPO Patent Application WO/2011/075701
Kind Code:
A4
Abstract:
Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
Inventors:
MORIARTY ROBERT M (US)
REID JOHN GREGORY (US)
SWARINGEN JR ROY A (US)
REID JOHN GREGORY (US)
SWARINGEN JR ROY A (US)
Application Number:
PCT/US2010/061150
Publication Date:
September 13, 2012
Filing Date:
December 17, 2010
Export Citation:
Assignee:
KYTHERA BIOPHARMACEUTICALS INC (US)
MORIARTY ROBERT M (US)
REID JOHN GREGORY (US)
SWARINGEN JR ROY A (US)
MORIARTY ROBERT M (US)
REID JOHN GREGORY (US)
SWARINGEN JR ROY A (US)
International Classes:
C07J1/00; C07J5/00; C07J9/00; C07J13/00; C07J41/00
Attorney, Agent or Firm:
SWISS, Gerald, F. et al. (975 Page Mill RoadPalo Alto, California, US)
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