MICROSTRUCTURE FORMULATION TECHNIQUE FOR BOTULINUM TOXIN

Title:

MICROSTRUCTURE FORMULATION TECHNIQUE FOR BOTULINUM TOXIN

Document Type and Number:

WIPO Patent Application WO/2021/086123

Kind Code:

A1

Abstract:

The present invention relates to a microstructure formulation technique for botulinum toxin. The microstructure formulation technique for botulinum toxin according to the present invention enables the concentration of botulinum toxin to be finely adjusted, alleviates pain when administered into the human body, and enables the toxin to be injected at an accurate administration position. Thus, the technique is expected to be greatly utilized in the safe and convenient medical use of botulinum toxin.

Inventors:

MOON KYEONG YEOP (KR)
LEE CHANG JIN (KR)
KIM DAE GUN (KR)
OH DONG HOON (KR)
KANG DO HYUN (KR)
LEE WOO RAN (KR)
SHIN JUHYUNG (KR)
LEE JEONG GYU (KR)
YOON MYEONGHEE (KR)

Application Number:

PCT/KR2020/015063

Publication Date:

May 06, 2021

Filing Date:

October 30, 2020

Export Citation:

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Assignee:

HUGEL INC (KR)
SMALLLAB CO LTD (KR)

International Classes:

A61M37/00; A61K9/00; A61K38/48; A61K47/26; A61K47/32; A61K47/36

Foreign References:

KR20180081689A	2018-07-17
KR101395064B1	2014-05-19
KR20190008832A	2019-01-25
US20140188041A1	2014-07-03

Other References:

B.M. TORRISI, ET AL.: "Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 165, no. 2, 1 January 2013 (2013-01-01), AMSTERDAM, NL, pages 146 - 152, XP055435125, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2012.11.010
SCHANT, E. J. ET AL., MICROBIOL. REV., vol. 56, 1992, pages 80
DUNNING FM, J VIS EXP., 3 March 2014 (2014-03-03), pages 85