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Title:
MNEP MONOMER VARIANT AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/056599
Kind Code:
A1
Abstract:
Provided are a Mnep monomer variant comprising an amino acid sequence with any one or plurality of amino acid mutations at positions 92-104 of SEQ ID NO: 1, a pore protein or construct comprising at least one Mnep monomer variant, and a use thereof. Also provided is a method for characterising a target polynucleotide.

Inventors:
LIU SHAOWEI (CN)
ZHOU YA (CN)
CHEN CHENGYAO (CN)
Application Number:
PCT/CN2019/109333
Publication Date:
April 01, 2021
Filing Date:
September 30, 2019
Export Citation:
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Assignee:
QITAN TECH LTD BEIJING (CN)
International Classes:
C07K14/35; C12N15/31
Domestic Patent References:
WO2016132123A12016-08-25
Foreign References:
CN103460040A2013-12-18
CN106459159A2017-02-22
CN107207571A2017-09-26
CN106460061A2017-02-22
CN106103741A2016-11-09
Other References:
DATABASE PROTEIN 8 August 2018 (2018-08-08), ANONYMOUS: "porin [Mycolicibacterium neoaurum]", XP055795783, retrieved from FASTA Database accession no. AXK74225
GUO BING-YUAN; ZENG TAO; WU HAI-CHEN: "Recent advances of DNA sequencing via nanopore-based technologies", SCIENCE BULLETIN, ZHONGGUO KEXUE ZAZHISHE, CN, vol. 60, no. 3, 26 December 2014 (2014-12-26), CN, pages 287 - 295, XP035441436, ISSN: 2095-9273, DOI: 10.1007/s11434-014-0707-6
Attorney, Agent or Firm:
BEIJING LINKTEC IP LAW FIRM (SPECIAL GENERAL PARTNERSHIP) (CN)
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