Title:
MODULATORS OF THE INTEGRATED STRESS PATHWAY
Document Type and Number:
WIPO Patent Application WO/2019/090085
Kind Code:
A8
Abstract:
Provided herein are compounds of formula (I), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases, disorders and conditions. (Formula I).
Inventors:
MARTIN KATHLEEN (US)
SIDRAUSKI CARMELA (US)
FROST JENNIFER (US)
TONG YUNSONG (US)
XU XIANGDONG (US)
CHUNG SEUNGWON (US)
ZHANG QINGWEI (US)
SHI LEI (US)
MURAUSKI KATHLEEN (US)
DART MICHAEL (US)
RANDOLPH JOHN (US)
SIDRAUSKI CARMELA (US)
FROST JENNIFER (US)
TONG YUNSONG (US)
XU XIANGDONG (US)
CHUNG SEUNGWON (US)
ZHANG QINGWEI (US)
SHI LEI (US)
MURAUSKI KATHLEEN (US)
DART MICHAEL (US)
RANDOLPH JOHN (US)
Application Number:
PCT/US2018/058969
Publication Date:
July 02, 2020
Filing Date:
November 02, 2018
Export Citation:
Assignee:
CALICO LIFE SCIENCES LLC (US)
ABBVIE INC (US)
ABBVIE INC (US)
International Classes:
C07C233/00; A61K31/16; A61K31/165; A61K31/352; A61K31/36; A61K31/498; A61K31/538; A61P3/00; A61P19/00; A61P21/00; A61P25/00; A61P29/00; A61P35/00; C07C235/00; C07C237/00; C07D207/22; C07D209/42; C07D265/36; C07D307/84; C07D311/66; C07D319/20; C07D405/12; C07D413/06; C07D493/04
Attorney, Agent or Firm:
MCCARTY, Catherine, M. et al. (US)
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