Title:
MOLECULAR DIAGNOSIS AND TREATMENT FORMULATION FOR ENDOMETRIOSIS, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/016751
Kind Code:
A1
Abstract:
Provided are a molecular diagnosis and treatment formulation, a preparation method therefor and use thereof. The formulation comprises: (1) an effect component, i.e. a diagnostic compound and/or a drug for treating endometriosis; and (2) a targeting component, i.e. a polypeptide having targeting recognition capability. The polypeptide comprises a polypeptide which is one or a combination of more of the following sequences or a derivative of the polypeptide which is one or a combination of more of the following sequences: SEQ ID No.1, SEQ ID No.2, SEQ ID No.3, SEQ ID No.4, SEQ ID No.5 and SEQ ID No.6. Said formulation is suitable for the diagnosis and/or treatment of endometriosis diseases in human, and can also be used as a research tool for an experimental animal for endometriosis.
Inventors:
ZHAO HUASHAN (CN)
ZHANG JIAN (CN)
ZHANG JIAN (CN)
Application Number:
PCT/CN2020/129877
Publication Date:
January 27, 2022
Filing Date:
November 18, 2020
Export Citation:
Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
A61K31/337; A61K47/64; A61K31/704; A61K35/00; A61K45/00; A61K49/00; A61K49/04; A61K49/14; A61K49/22; A61P35/00; C07K14/445; C07K17/00
Domestic Patent References:
| WO2015095952A1 | 2015-07-02 |
Foreign References:
| CN109568597A | 2019-04-05 | |||
| CN109387627A | 2019-02-26 |
Other References:
LI, MENG ET AL.: "Research Progress on Pregnancy-Associated Malaria", JOURNAL OF TROPICAL MEDICINE, vol. 8, no. 12, 31 December 2008 (2008-12-31), pages 1287 - 1293, XP055889072
PROFESSIONAL COMMITTEE OF GYNECOLOGY AND OBSTETRICS, CHINESE ASSOCIATION OF INTEGRATIVE MEDICINE: "Guidelines for Endometriosis by Integrated Traditional Chinese and Western Medicine", CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE, vol. 39, no. 10, 31 October 2019 (2019-10-31), pages 1169 - 1176, XP055889325
GAMAIN BENOIT, TRIMNELL ADAMA R, SCHEIDIG CHRISTINE, SCHERF ARTUR, MILLER LOUIS H, SMITH JOSEPH D: "Identification of Multiple Chondroitin Sulfate A (CSA)–Binding Domains in the var2CSA Gene Transcribed in CSA-Binding Parasites.", THE JOURNAL OF INFECTIOUS DISEASES, vol. 191, 11 February 2005 (2005-02-11), pages 1010 - 1013, XP055889326
PROFESSIONAL COMMITTEE OF GYNECOLOGY AND OBSTETRICS, CHINESE ASSOCIATION OF INTEGRATIVE MEDICINE: "Guidelines for Endometriosis by Integrated Traditional Chinese and Western Medicine", CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE, vol. 39, no. 10, 31 October 2019 (2019-10-31), pages 1169 - 1176, XP055889325
GAMAIN BENOIT, TRIMNELL ADAMA R, SCHEIDIG CHRISTINE, SCHERF ARTUR, MILLER LOUIS H, SMITH JOSEPH D: "Identification of Multiple Chondroitin Sulfate A (CSA)–Binding Domains in the var2CSA Gene Transcribed in CSA-Binding Parasites.", THE JOURNAL OF INFECTIOUS DISEASES, vol. 191, 11 February 2005 (2005-02-11), pages 1010 - 1013, XP055889326
Attorney, Agent or Firm:
BEIJING ZHONG XUN TONG DA INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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