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Title:
MOLECULE ANALYZING METHOD USING MICROCHANNEL
Document Type and Number:
WIPO Patent Application WO/2004/010140
Kind Code:
A1
Abstract:
A novel method for analyzing a specimen molecule with high accuracy through a simple operation by forming a laminar flow of a specimen molecule containing solution and a complex forming molecule containing solution in a microchannel and measuring the variation of the degree of diffusion of complexes each composed of a specimen molecule and a complex forming molecule in the laminar flow. The complex forming molecule is fluorescent, and the variation of the degree of diffusion of the formed complexes is measured from the distribution of intensity of fluorescence. The degree of diffusion of the formed complexes can be quantitatively determined by comparing it with a calibration curve preliminarily defined.

Inventors:
YAMASHITA KENICHI (JP)
MAEDA HIDEAKI (JP)
SHIMIZU HAJIME (JP)
MIYAZAKI MASAYA (JP)
NAKAMURA HIROYUKI (JP)
YAMAGUCHI YOSHIKO (JP)
Application Number:
PCT/JP2003/009142
Publication Date:
January 29, 2004
Filing Date:
July 18, 2003
Export Citation:
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Assignee:
NAT INST OF ADVANCED IND SCIEN (JP)
YAMASHITA KENICHI (JP)
MAEDA HIDEAKI (JP)
SHIMIZU HAJIME (JP)
MIYAZAKI MASAYA (JP)
NAKAMURA HIROYUKI (JP)
YAMAGUCHI YOSHIKO (JP)
International Classes:
G01N31/20; B01L3/00; G01N21/64; G01N33/53; G01N33/536; G01N33/566; G01N37/00; B01F5/06; B01F13/00; G01N13/00; (IPC1-7): G01N33/53; G01N31/00; G01N37/00
Domestic Patent References:
WO2000022434A12000-04-20
WO2000072020A12000-11-30
Foreign References:
JP2001518624A2001-10-16
Attorney, Agent or Firm:
Agata, Akira (3rd Floor Ikenden Building, 12-5, Shimbashi 2-chom, Minato-ku Tokyo, JP)
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