MULTIVALENT MENINGOCOCCAL DERIVATIZED POLYSACCHARIDE-PROTEIN CONJUGATES AND VACCINE

Title:

MULTIVALENT MENINGOCOCCAL DERIVATIZED POLYSACCHARIDE-PROTEIN CONJUGATES AND VACCINE

Document Type and Number:

WIPO Patent Application WO2006034320

Kind Code:

A3

Abstract:

The present invention describes derivatized polysaccharide-protein conjugates, a composition comprising one or more of such derivatized polysaccharide-protein conjugates and methods of immunizing human patients with the same. The derivatized polysaccharide protein conjugates are purified capsular polysaccharides from Neisseria meningitidis serogroups A, C, W- 135, and Y, derivatized chemically activated and selectively attached to a carrier protein by means of a covalent chemical bond, forming polysaccharide-protein conjugates capable of eliciting long-lasting immunity to a variety of N. meningitidis strains.

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Inventors:

RYALL ROBERT P (US)

Application Number:

PCT/US2005/033761

Publication Date:

September 28, 2006

Filing Date:

September 21, 2005

Export Citation:

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Assignee:

SANOFI PASTEUR INC (US)
RYALL ROBERT P (US)

International Classes:

A61K39/00; A61K39/385; A61K39/02; A61K39/095; A61K39/116; C07H1/00

Foreign References:

US6146902A	2000-11-14
US20030068336A1	2003-04-10

Other References: