Title:
MUSCLE TISSUE-REGENERATING AGENT
Document Type and Number:
WIPO Patent Application WO/2021/066078
Kind Code:
A1
Abstract:
[Problem] To provide a muscle tissue-regenerating agent containing fibroin protein. [Solution] This muscle tissue-regenerating agent contains modified fibroin protein.
Inventors:
UCHIDA HIROO (JP)
NAGATA HIZURU (JP)
HINOKI AKINARI (JP)
FUJII MASATAKA (JP)
CHUANG YU CHUN (JP)
HARADA SATOSHI (JP)
SATO TAKEHIRO (JP)
NAGATA HIZURU (JP)
HINOKI AKINARI (JP)
FUJII MASATAKA (JP)
CHUANG YU CHUN (JP)
HARADA SATOSHI (JP)
SATO TAKEHIRO (JP)
Application Number:
PCT/JP2020/037354
Publication Date:
April 08, 2021
Filing Date:
September 30, 2020
Export Citation:
Assignee:
SPIBER INC (JP)
TOKAI NATIONAL HIGHER EDUCATION AND RES SYSTEM (JP)
TOKAI NATIONAL HIGHER EDUCATION AND RES SYSTEM (JP)
International Classes:
A61K38/16; A61K9/14; A61K9/70; A61K47/10; A61K47/20; A61P17/02; A61P21/00; C12N15/12
Domestic Patent References:
| WO2005103158A1 | 2005-11-03 |
Foreign References:
| JP2019131923A | 2019-08-08 | |||
| JP2017532178A | 2017-11-02 | |||
| JP2012505297A | 2012-03-01 | |||
| JP2018150637A | 2018-09-27 | |||
| JP2020121962A | 2020-08-13 | |||
| AM490169U | ||||
| JP2002238569A | 2002-08-27 | |||
| JP6077570B2 | 2017-02-08 | |||
| JP6077569B2 | 2017-02-08 | |||
| JP5584932B2 | 2014-09-10 | |||
| JP5796147B2 | 2015-10-21 | |||
| JP2017539869A | 2016-09-08 | |||
| JP2016076500W | 2016-09-08 | |||
| JP5782580B2 | 2015-09-24 |
Other References:
SCHAFER-NOLTE, F. ET AL.: "Biomechanics and biocompatibility of woven spider silk meshes during remodeling in a rodent fascia replacement model", ANNALS OF SURGERY, vol. 259, no. 4, pages 781 - 792, DOI: http://dx.doi.org/ 10.1097/SLA.Ob013e3182917677
CHATURVEDI, VISHAL, NASKAR DEBOKI, KINNEAR BEVERLEY F., GRENIK ELIZABETH, DYE DANIELLE E., GROUNDS MIRANDA D., KUNDU SUBHAS C., CO: "Silk fibroin scaffolds with muscle-like elasticity support in vitro differentiation of human skeletal muscle cells", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, vol. 11, no. 11, 2017, pages 3178 - 3192, XP055811434, DOI: 10.1002/term.2227
BAUER, FELIX, WOHLRAB STEFANIE, SCHEIBEL THOMAS: "Controllable cell adhesion, growth and orientation on layered silk protein films", BIOMATERIALS SCIENCE, vol. 1, 2013, pages 1244 - 1249, XP055811441, DOI: 10.1039/c3bm60114e
NUCLEIC ACID RES, vol. 10, 1982, pages 6487
METHODS IN ENZYMOLOGY, vol. 100, 1983, pages 448
"GenBank", Database accession no. ABR37278.1
KYTE JDOOLITTLE R: "A simple method for displaying the hydropathic character of a protein", J. MOL. BIOL., vol. 157, 1982, pages 105 - 132, XP024014365, DOI: 10.1016/0022-2836(82)90515-0
PROC. NATL. ACAD. SCI. USA, vol. 69, 1972, pages 2110
"Molecular Cloning"
CHATURVEDI, VISHAL, NASKAR DEBOKI, KINNEAR BEVERLEY F., GRENIK ELIZABETH, DYE DANIELLE E., GROUNDS MIRANDA D., KUNDU SUBHAS C., CO: "Silk fibroin scaffolds with muscle-like elasticity support in vitro differentiation of human skeletal muscle cells", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, vol. 11, no. 11, 2017, pages 3178 - 3192, XP055811434, DOI: 10.1002/term.2227
BAUER, FELIX, WOHLRAB STEFANIE, SCHEIBEL THOMAS: "Controllable cell adhesion, growth and orientation on layered silk protein films", BIOMATERIALS SCIENCE, vol. 1, 2013, pages 1244 - 1249, XP055811441, DOI: 10.1039/c3bm60114e
NUCLEIC ACID RES, vol. 10, 1982, pages 6487
METHODS IN ENZYMOLOGY, vol. 100, 1983, pages 448
"GenBank", Database accession no. ABR37278.1
KYTE JDOOLITTLE R: "A simple method for displaying the hydropathic character of a protein", J. MOL. BIOL., vol. 157, 1982, pages 105 - 132, XP024014365, DOI: 10.1016/0022-2836(82)90515-0
PROC. NATL. ACAD. SCI. USA, vol. 69, 1972, pages 2110
"Molecular Cloning"
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