Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
MVIN PROTEIN MUTANT, EXPRESSION VECTOR AND HOST CELL INCLUDING SAID MUTANT, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/035793
Kind Code:
A1
Abstract:
Provided is an MviN protein mutant, said mutant improving corynebacterium glutamic acid and lysine production capability by means of introducing an amino acid mutation at a set position in an MviN protein amino acid sequence.

Inventors:
SUN JIBIN (CN)
LI QINGGANG (CN)
ZHOU WENJUAN (CN)
DELE-OSIBANJO TAIWO ADEOLU (CN)
ZHENG PING (CN)
MA YANHE (CN)
Application Number:
PCT/CN2019/104683
Publication Date:
March 04, 2021
Filing Date:
September 06, 2019
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
TIANJIN INST IND BIOTECHNOLOGY CAS (CN)
International Classes:
C12N9/00; C12N1/21; C12N15/52; C12P13/08; C12P13/14; C12R1/15
Foreign References:
JP2010161970A2010-07-29
CN1578834A2005-02-09
Other References:
ULLAND TYLER K., BUCHAN BLAKE W., KETTERER MARGARET R., FERNANDES-ALNEMRI TERESA, MEYERHOLZ DAVID K., APICELLA MICHAEL A., ALNEMRI: "Cutting Edge: Mutation of Francisella tularensis mviN Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence", THE JOURNAL OF IMMUNOLOGY, WILLIAMS & WILKINS CO., US, vol. 185, no. 5, 1 September 2010 (2010-09-01), US, pages 2670 - 2674, XP055788343, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1001610
RUDNICK PAUL A., ARCONDÉGUY TANIA, KENNEDY CHRISTINA K., KAHN DANIEL: "glnD and mviN Are Genes of an Essential Operon in Sinorhizobium meliloti", JOURNAL OF BACTERIOLOGY, vol. 183, no. 8, 15 April 2001 (2001-04-15), pages 2682 - 2685, XP055788340, ISSN: 0021-9193, DOI: 10.1128/JB.183.8.2682-2685.2001
DATABASE Protein NCBI; 27 May 2013 (2013-05-27), "membrane protein [Corynebacterium glutamicum]", XP055788316, Database accession no. WP_003855292
DATABASE Protein NCBI; 28 January 2015 (2015-01-28), "membrane protein [Corynebacterium glutamicum]", XP055788322, Database accession no. WP_040968107
DATABASE Protein NCBI; 27 January 2016 (2016-01-27), "murein biosynthesis protein MurJ [Corynebacterium glutamicum]", XP055788329, Database accession no. WP_060565439
DATABASE Protien NCBI; 22 March 2015 (2015-03-22), "virulence factor [Corynebacterium glutamicum]", XP055788336, Database accession no. WP_011015622
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
Download PDF: