Title:
NANO-ANTIBODY TARGETING CAIX ANTIGEN AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/047386
Kind Code:
A1
Abstract:
Provided are an anti-CAIX single-domain antibody and a VHH chain thereof, as well as a related coding sequence, expression vector and host cell; also provided are a production method for said CAIX single-domain antibody and an application thereof.
Inventors:
MIAO XIAONIU (CN)
XU YIFENG (CN)
YI GANG (CN)
LI ZHIYUAN (CN)
TSUN ANDY (CN)
LIU XIAOLIN (CN)
XU YIFENG (CN)
YI GANG (CN)
LI ZHIYUAN (CN)
TSUN ANDY (CN)
LIU XIAOLIN (CN)
Application Number:
PCT/CN2020/111112
Publication Date:
March 18, 2021
Filing Date:
August 25, 2020
Export Citation:
Assignee:
BIOTHEUS INC (CN)
International Classes:
C07K16/40; A61K39/00; A61K39/395; A61P35/00; C07K16/28; C12N15/11; C12N15/63
Domestic Patent References:
| WO2018157147A1 | 2018-08-30 |
Foreign References:
| CN109797171A | 2019-05-24 |
Other References:
BRATTAIN LAURA J.; TELFER BRIAN A.; DHYANI MANISH; GRAJO JOSEPH R.; SAMIR ANTHONY E.: "Machine learning for medical ultrasound: status, methods, and future opportunities", ABDOMINAL RADIOLOGY, SPRINGER US, NEW YORK, vol. 43, no. 4, 28 February 2018 (2018-02-28), New York, pages 786 - 799, XP036472474, ISSN: 2366-004X, DOI: 10.1007/s00261-018-1517-0
AZIZI SHEKOOFEH; BAYAT SHARAREH; YAN PINGKUN; TAHMASEBI AMIR; NIR GUY; KWAK JIN TAE; XU SHENG; WILSON STOREY; ICZKOWSKI KENNETH A.: "Detection and grading of prostate cancer using temporal enhanced ultrasound: combining deep neural networks and tissue mimicking simulations", INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY, SPRINGER, DE, vol. 12, no. 8, 20 June 2017 (2017-06-20), DE, pages 1293 - 1305, XP036290813, ISSN: 1861-6410, DOI: 10.1007/s11548-017-1627-0
AZIZI SHEKOOFEH; BAYAT SHARAREH; YAN PINGKUN; TAHMASEBI AMIR; NIR GUY; KWAK JIN TAE; XU SHENG; WILSON STOREY; ICZKOWSKI KENNETH A.: "Detection and grading of prostate cancer using temporal enhanced ultrasound: combining deep neural networks and tissue mimicking simulations", INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY, SPRINGER, DE, vol. 12, no. 8, 20 June 2017 (2017-06-20), DE, pages 1293 - 1305, XP036290813, ISSN: 1861-6410, DOI: 10.1007/s11548-017-1627-0
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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