NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY

Title:

NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY

Document Type and Number:

WIPO Patent Application WO1998003518

Kind Code:

A3

Abstract:

Bis-platinum(II) complexes with polymethylene derivatives, the method of making the complexes, and the use of the complexes for the treatment of tumors in mammals, are disclosed. The method of making the polymethylene derivatives, is also disclosed.

Inventors:

FARRELL NICHOLAS P (US)
MENTA ERNESTO (IT)
DI DOMENICO ROBERTO (IT)
SPINELLI SILVANO (IT)

Application Number:

PCT/US1997/012552

Publication Date:

April 17, 2003

Filing Date:

July 22, 1997

Export Citation:

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Assignee:

HOFFMANN LA ROCHE (CH)
UNIV VIRGINIA COMMONWEALTH (US)
FARRELL NICHOLAS P (US)
MENTA ERNESTO (IT)
DI DOMENICO ROBERTO (IT)
SPINELLI SILVANO (IT)

International Classes:

A61K31/282; C07C231/02; C07C231/12; C07C231/14; A61P35/00; C07C273/18; C07C277/08; C07C303/34; C07F15/00; C07C233/56; C07C237/10; C07C275/14; C07C279/12; C07C279/24; C07C307/06; (IPC1-7): C07F15/00; A61K31/28; C07C231/00; C07C303/34; C07C277/08; C07C273/18

Domestic Patent References:

WO1988000947A1	1988-02-11
WO1991003482A1	1991-03-21
WO1995026968A1	1995-10-12

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