Title:
NEW CRYSTAL FORM OF DAPAGLIFLOZIN AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2016/155578
Kind Code:
A1
Abstract:
The present invention relates to a crystal form I of Dapagliflozin which is a medicine for treating type II diabetes, and a preparation method therefor. The crystal form I is characterized in that an x-ray powder diffraction pattern has characteristic peaks when 2theta values are 15.8°±0.2°, 19.8°±0.2° and 28.7°±0.2°. Compared with the prior art, the crystal form I has better stability, facilitates the long-term storage of a medicine, and avoids crystal transformation during medicine development and storage. The preparation method is simple, facilitates cost control in technological production, and has very high economic value.
Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
YANG CHAOHUI (CN)
LU FEI (CN)
YANG CUNBO (CN)
ZHANG XIAOYU (CN)
ZHANG YANFENG (CN)
YANG CHAOHUI (CN)
LU FEI (CN)
YANG CUNBO (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2016/077405
Publication Date:
October 06, 2016
Filing Date:
March 25, 2016
Export Citation:
Assignee:
CRYSTAL PHARMATECH CO LTD (CN)
International Classes:
C07D309/10; A61K31/351; A61P3/10
Domestic Patent References:
| WO2013079501A1 | 2013-06-06 | |||
| WO2008002824A1 | 2008-01-03 |
Foreign References:
| CN104045615A | 2014-09-17 | |||
| CN104382859A | 2015-03-04 | |||
| EP2529742A1 | 2012-12-05 |
Attorney, Agent or Firm:
BOSS&YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
北京邦信阳专利商标代理有限公司 (CN)
北京邦信阳专利商标代理有限公司 (CN)
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