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Patent Searching and Data


Title:
NEW TORALACTONE AND ITS DERIVATION AND THE USE OF DECREASING BLOOD-FAT AND LOSING WEIGHT
Document Type and Number:
WIPO Patent Application WO/2001/060390
Kind Code:
A1
Abstract:
New toralactone of general formula [A] extracted from seed of cassiae obtusifollia L. and its derivative, wherein R?3¿ is H or acyl of C¿2?-C¿4?, R?1¿, R?2¿ is identity or difference, independently H, saccharide group, acyl of C¿2?-C¿4?. The said compound can reduce serumal general cholesterol and increase the amount of general bile acid, manifesting that these compounds have the effect of decreasing blood-fat and losing weight.

Inventors:
PAN XIAODONG (CN)
Application Number:
PCT/CN2001/000123
Publication Date:
August 23, 2001
Filing Date:
February 13, 2001
Export Citation:
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Assignee:
PAN XIAODONG (CN)
International Classes:
C07H17/04; A61K31/366; A61K31/7048; A61K36/00; A61P3/04; A61P3/06; C07D311/92; (IPC1-7): A61K35/78; A61K31/21
Foreign References:
Other References:
KITANAKA ET AL.: "Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of cassia obtusfolia L", CHEM. PHARM. BULL., vol. 46, no. 10, 1998, pages 1650 - 1652, XP002233242
HATANO ET AL.: "Phenolic constituents of cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant staphylococcus aureus", CHEM. PHARM. BULL., vol. 47, no. 8, 1999, pages 1121 - 1127, XP002233243
TALAHASHI ET AL.: "Purgative crude drugs. VII. Constituents of the seeds of cassia tora. II. Structure of new naphtho-. alpha. -pyrone derivative, toralactone", YAKUGAKU ZASSHI, vol. 93, no. 3, 1973, pages 261 - 267, XP002963144
KITANAKA ET AL.: "Studies of the constituents of purgative crude drugs. Part II. Studies on the constituents of the seeds of Cassia obtusifolia: The structures of two new lactones, isotoralactone and cassialactone", PHYTOCHEMISTRY, vol. 20, no. 8, 1981, pages 1951 - 1953, XP002963145
See also references of EP 1256350A4
Attorney, Agent or Firm:
NTD PATENT & TRADEMARK AGENCY LTD., BEIJING OFFICE (Block A Investment Plaza 27 Jinrongdajie Beijing 2, CN)
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