Title:
NITROGEN-CONTAINING HETEROCYCLIC MODIFIED COMPOUNDS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/083543
Kind Code:
A1
Abstract:
A nitrogen-containing heterocyclic modified compounds and their uses in preparing the medicaments of preventing and treating the Alzheimer's disease, Parkinson's disease and other degenerative nervous system disease or type two diabetes. Studies show that the provided compounds can inhibit aggregation of Aβ, also can make the Aβ aggregated depolymerize, and will eventually hydrolysic eliminate the Aβ protein, inhibit and remove the Aβ toxicity, the said compounds has broad application prospects in the field of medicine.
Inventors:
LEI PENG (CN)
LI YANMEI (CN)
WU WEIHUI (CN)
SU XIAOYANG (CN)
HU JIA (CN)
LI YANMEI (CN)
WU WEIHUI (CN)
SU XIAOYANG (CN)
HU JIA (CN)
Application Number:
PCT/CN2007/002985
Publication Date:
July 17, 2008
Filing Date:
October 18, 2007
Export Citation:
Assignee:
UNIV TSINGHUA (CN)
LEI PENG (CN)
LI YANMEI (CN)
WU WEIHUI (CN)
SU XIAOYANG (CN)
HU JIA (CN)
LEI PENG (CN)
LI YANMEI (CN)
WU WEIHUI (CN)
SU XIAOYANG (CN)
HU JIA (CN)
International Classes:
C07D257/02; A61K31/05; A61K31/12; A61K31/19; A61K31/216; A61K31/665; A61K38/08; A61P3/10; A61P25/16; A61P25/28; C07C229/16; C07C237/06; C07D225/02; C07K7/06
Domestic Patent References:
| WO2006117077A1 | 2006-11-09 |
Foreign References:
| CN100999496A | 2007-07-18 | |||
| CN100999495A | 2007-07-18 | |||
| CN100999546A | 2007-07-18 |
Attorney, Agent or Firm:
JEEKAI & PARTNERS (Jinyu Tower A129 West Xuan Wu Men Street XiChengDistrict, Beijing, CN)
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