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Title:
NOVEL 16-MEMBERED CYCLIC 4”-0-CARBAMOYL AZALIDE DERIVATIVE AND PROCESS FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2007/069555
Kind Code:
A1
Abstract:
Disclosed is a compound represented by the general formula (1) below or a pharmaceutically acceptable salt thereof. Also disclosed are a process for producing such a compound or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition and antibacterial agent containing such a compound or a pharmaceutically acceptable salt thereof. (1) [In the formula, R1 represents a hydrogen atom or a C2-6 linear alkylcarbonyl group; R2 represents a hydrogen atom or a C2-6 alkylcarbonyl group; R3 represents a C1-6 alkyl group which may be substituted by a hydroxyl group or the like; R4 represents a hydrogen atom, a C1-6 alkyl group, a C2-6 alkenyl group, an Ar-B- group (wherein Ar represents an aryl group or a heterocyclic group, and B represents a C1-6 alkyl group or a C2-6 alkenyl group) or the like; and R5 and R6 independently represent a hydrogen atom, a C1-6 alkyl group which may be substituted by a hydroxyl group, or a C2-6 alkenyl group.]

Inventors:
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
NATSUME SATOMI (JP)
WATANABE TAKASHI (JP)
YOSHIDA TAKUJI (JP)
SUZUKI HISASHI (JP)
Application Number:
PCT/JP2006/324641
Publication Date:
June 21, 2007
Filing Date:
December 11, 2006
Export Citation:
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Assignee:
MEIJI SEIKA KAISHA (JP)
MIURA TOMOAKI (JP)
KANEMOTO KENICHI (JP)
NATSUME SATOMI (JP)
WATANABE TAKASHI (JP)
YOSHIDA TAKUJI (JP)
SUZUKI HISASHI (JP)
International Classes:
C07H17/08; A61K31/7048; A61P31/04
Domestic Patent References:
WO2005019238A12005-03-03
Foreign References:
JPH02503793A1990-11-08
Other References:
SHOMURA T. ET AL.: "9,3''-Diacetylmidecamycin no Taisha ni Kansuru Kenyku (Dai 1 Po), 9,3''-Diacetylmidecamycin no Tainai Dotai", JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 102, no. 8, 1982, pages 781 - 795, XP003014493
Attorney, Agent or Firm:
SIKs & Co. (Kyobashi-Nisshoku Bldg. 8-7, Kyobashi 1-chom, Chuo-ku Tokyo 31, JP)
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