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Title:
NOVEL ALKYLENE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/056782
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel compound having ACC2-inhibiting activity and to provide a pharmaceutical composition comprising said compound. A compound indicated by formula (in the formula, R1 indicates a substituted or unsubstituted condensed aromatic heterocyclic group, the ring A indicates a substituted or unsubstituted non-aromatic carbon ring, -L1- indicates -O-(CR6R7)m-, -L2- indicates -O-(CR6R7)n-, R6 and R7 each independently indicate hydrogen or halogen, R2 indicates a substituted or unsubstituted alkyl, R3 indicates hydrogen or a substituted or unsubstituted alkyl, and R4 indicates a substituted or unsubstituted alkyl carbonyl) or a pharmaceutically acceptable salt thereof.

Inventors:
KOBAYASHI NAOTAKE (JP)
ASAHI KENTAROU (JP)
TOMIDA YUTAKA (JP)
OHDAN MASAHIDE (JP)
FUMOTO MASATAKA (JP)
SASAKI YOSHIKAZU (JP)
KURAHASHI KANA (JP)
INOUE TAKATSUGU (JP)
URABE TOMOMI (JP)
NISHIURA YUJI (JP)
IWATSU MASAFUMI (JP)
MIYAZAKI KEISUKE (JP)
OHYABU NAOKI (JP)
WADA TOSHIHIRO (JP)
KATOU MANABU (JP)
Application Number:
JP2014/077700
Publication Date:
April 23, 2015
Filing Date:
October 17, 2014
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
International Classes:
C07C233/18; A61K31/165; A61K31/17; A61K31/416; A61K31/423; A61K31/426; A61K31/44; A61K31/4418; A61K31/4439; A61K31/4725; A61K31/4965; A61K31/497; A61K31/506; A61K31/517; A61K31/553; A61P3/04; A61P3/10; A61P43/00; C07C233/31; C07C275/24; C07D213/64; C07D213/69; C07D231/56; C07D239/80; C07D241/18; C07D261/20; C07D267/14; C07D277/20; C07D277/34; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D413/12; C07D417/12
Domestic Patent References:
WO2014061693A12014-04-24
WO2008079610A22008-07-03
WO2010003624A22010-01-14
WO2010050445A12010-05-06
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Other References:
See also references of EP 3059225A4
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Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
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