Title:
NOVEL CARBAPENEM DERIVATIVES OF QUATERNARY SALT TYPE
Document Type and Number:
WIPO Patent Application WO/2001/055155
Kind Code:
A1
Abstract:
Carbapenem derivatives having potent antimicrobial activities on MRSA, PRSP, influenza viruses and $g(b)-lactamase-producing bacteria and a high stability to DHP-1. Namely, compounds represented by the general formula (I) or pharmaceutically acceptable salts thereof, wherein R?1¿ represents H or methyl; R?2¿ and R?3¿ represent each H, halogeno, lower alkyl, etc.; R?4¿ represents optionally substituted lower alkylthio, etc.; and R?5¿ represents optionally substituted lower alkyl, etc.
Inventors:
KANO YUKO (JP)
MARUYAMA TAKAHISA (JP)
YAMAMOTO YASUO (JP)
SHITARA EIKI (JP)
SASAKI TOSHIRO (JP)
AIHARA KAZUHIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
IDA TAKASHI (JP)
MARUYAMA TAKAHISA (JP)
YAMAMOTO YASUO (JP)
SHITARA EIKI (JP)
SASAKI TOSHIRO (JP)
AIHARA KAZUHIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
IDA TAKASHI (JP)
Application Number:
PCT/JP2001/000529
Publication Date:
August 02, 2001
Filing Date:
January 26, 2001
Export Citation:
Assignee:
MEIJI SEIKA KAISHA (JP)
KANO YUKO (JP)
MARUYAMA TAKAHISA (JP)
YAMAMOTO YASUO (JP)
SHITARA EIKI (JP)
SASAKI TOSHIRO (JP)
AIHARA KAZUHIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
IDA TAKASHI (JP)
KANO YUKO (JP)
MARUYAMA TAKAHISA (JP)
YAMAMOTO YASUO (JP)
SHITARA EIKI (JP)
SASAKI TOSHIRO (JP)
AIHARA KAZUHIRO (JP)
ATSUMI KUNIO (JP)
IWAMATSU KATSUYOSHI (JP)
IDA TAKASHI (JP)
International Classes:
A61P31/04; C07D477/14; C07D519/00; C07D519/06; (IPC1-7): C07D519/00; A61K31/429; A61P31/04
Domestic Patent References:
| WO2000006581A1 | 2000-02-10 | |||
| WO1998032760A1 | 1998-07-30 | |||
| WO1998023623A1 | 1998-06-04 | |||
| WO1996028455A1 | 1996-09-19 |
Other References:
See also references of EP 1251134A4
Attorney, Agent or Firm:
Yoshitake, Kenji (Fuji Bldg. 2-3 Marunouchi 3-chome Chiyoda-ku, Tokyo, JP)
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