Title:
NOVEL CATIONIC LIPID HAVING CYSTINE SKELETON
Document Type and Number:
WIPO Patent Application WO/2021/193397
Kind Code:
A1
Abstract:
The present invention provides a cationic lipid represented by formula (1) (wherein each symbol is as defined in the description), a lipid membrane structure using the cationic lipid, a nucleic acid transfection agent using the cationic lipid, and a method of nucleic acid transfection using the nucleic acid transfection agent.
Inventors:
TAMAGAWA SHINYA (JP)
TANGE KOTA (JP)
NAKAI YUTA (JP)
TAMADA MASAMICHI (JP)
AKITA HIDETAKA (JP)
TANAKA HIROKI (JP)
SAKURAI YU (JP)
TANGE KOTA (JP)
NAKAI YUTA (JP)
TAMADA MASAMICHI (JP)
AKITA HIDETAKA (JP)
TANAKA HIROKI (JP)
SAKURAI YU (JP)
Application Number:
PCT/JP2021/011298
Publication Date:
September 30, 2021
Filing Date:
March 19, 2021
Export Citation:
Assignee:
NOF CORP (JP)
UNIV CHIBA NAT UNIV CORP (JP)
UNIV CHIBA NAT UNIV CORP (JP)
International Classes:
C12N15/87; A61K9/50; A61K47/54; A61K48/00; C07C321/20
Domestic Patent References:
WO2013050547A1 | 2013-04-11 | |||
WO2016121942A1 | 2016-08-04 | |||
WO2019188867A1 | 2019-10-03 |
Foreign References:
RU2233834C2 | 2004-08-10 | |||
US9708628B2 | 2017-07-18 | |||
US20180298379A1 | 2018-10-18 | |||
JP2020057383A | 2020-04-09 |
Other References:
BIOMATERIALS, vol. 29, no. 24-25, 2008, pages 3477 - 96
MOLECULAR THERAPY, vol. 24, no. 4, 2016, pages 788 - 795
ANGEWANTE CHEMIE INTERNATIONAL EDITION, vol. 51, 2012, pages 8529 - 8533
MOLECULAR THERAPY, vol. 13, no. 4, 2006, pages 786 - 794
"GREENE'S PROTECTIVE GROUPS IN ORGANIC SYNTHESIS", WILEY-INTERSCIENCEM
MOLECULAR THERAPY, vol. 24, no. 4, 2016, pages 788 - 795
ANGEWANTE CHEMIE INTERNATIONAL EDITION, vol. 51, 2012, pages 8529 - 8533
MOLECULAR THERAPY, vol. 13, no. 4, 2006, pages 786 - 794
"GREENE'S PROTECTIVE GROUPS IN ORGANIC SYNTHESIS", WILEY-INTERSCIENCEM
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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