Title:
NOVEL CHIRAL PHASE-TRANSFER CATALYST, AND METHOD FOR PREPARING Α-AMINO ACID BY USING SAME
Document Type and Number:
WIPO Patent Application WO/2017/200184
Kind Code:
A1
Abstract:
The present invention relates to a novel chiral phase-transfer catalyst, and a method for preparing an α-amino acid by using the same. According to the present invention, an α-amino acid could be chirally synthesized in a high yield under an easy industrially applicable reaction condition by using a novel cinchona alkaloid compound as a chiral phase-transfer catalyst, and thus the present invention can be used as a key technique of the α-amino acid synthesis and preparation field.
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Inventors:
NAHM KEE PYUNG (KR)
LEE YEON JI (KR)
LIM BAE GEUN (KR)
WOO SEUNG A (KR)
OH JI INN (KR)
SON WON GYOUNG (KR)
LEE YEON JI (KR)
LIM BAE GEUN (KR)
WOO SEUNG A (KR)
OH JI INN (KR)
SON WON GYOUNG (KR)
Application Number:
PCT/KR2017/001270
Publication Date:
November 23, 2017
Filing Date:
February 06, 2017
Export Citation:
Assignee:
UNIV YEUNGNAM RES COOPERATION FOUNDATION (KR)
International Classes:
C07D453/04; B01J31/02; C07C15/16; C07D401/06; C07D471/04
Foreign References:
| KR20030044364A | 2003-06-09 | |||
| KR20110005470A | 2011-01-18 |
Other References:
ASHOKKUMAR, V. ET AL.: "A New Class of Bifunctional Chiral Phase Transfer Catalysis for Highly Enantioselective Asymmetric Epoxidation of alpha, beta-unsaturated Ketones at Ambient Temperature", JOURNAL OF MOLECULAR CATALYSIS A: CHEMICAL, [ELECTRONIC PUBLISHING, vol. 409, 21 August 2015 (2015-08-21), pages 127 - 1 36, XP055549376
OOI, T. ET AL.: "Recent Advances in Asymmetric Phase-Transfer Catalysis", ANGEW. CHEM. INT. ED., vol. 46, no. 23, 2007, pages 4222 - 4266, XP055060024
ISLAM, M. R. ET AL.: "Synthesis of Chiral Polymers Containing Thioetherified Cinchonidinium Repeating Units and Their Application to Asymmetric Catalysis", TETRAHEDRON : ASYMMETRY, vol. 25, no. 18 / 19, 2014, pages 1309 - 1315, XP055549397
O'DONNELL, M. J.; BENNETT, W. D.; WU, S., J. AM. CHEM. SOC., vol. 111, 1989, pages 2353
LYGO, B.; WAINWRIGHT, P. G., TETRAHEDRON LETT., vol. 38, 1997, pages 8595
COREY, E.J.; XU, F.; NOE, M. C., J. AM. CHEM. SOC., vol. 119, 1997, pages 12414
PARK, H.-G.; JEONG, B.-S.; YOO, M.-S.; LEE, J.-H.; PARK, M.-K.; LEE, Y.-J.; KIM, M. -J.; JEW, S.-S., ANGEW. CHEM. INT. ED., vol. 41, 2002, pages 3036
OOI, T. ET AL.: "Recent Advances in Asymmetric Phase-Transfer Catalysis", ANGEW. CHEM. INT. ED., vol. 46, no. 23, 2007, pages 4222 - 4266, XP055060024
ISLAM, M. R. ET AL.: "Synthesis of Chiral Polymers Containing Thioetherified Cinchonidinium Repeating Units and Their Application to Asymmetric Catalysis", TETRAHEDRON : ASYMMETRY, vol. 25, no. 18 / 19, 2014, pages 1309 - 1315, XP055549397
O'DONNELL, M. J.; BENNETT, W. D.; WU, S., J. AM. CHEM. SOC., vol. 111, 1989, pages 2353
LYGO, B.; WAINWRIGHT, P. G., TETRAHEDRON LETT., vol. 38, 1997, pages 8595
COREY, E.J.; XU, F.; NOE, M. C., J. AM. CHEM. SOC., vol. 119, 1997, pages 12414
PARK, H.-G.; JEONG, B.-S.; YOO, M.-S.; LEE, J.-H.; PARK, M.-K.; LEE, Y.-J.; KIM, M. -J.; JEW, S.-S., ANGEW. CHEM. INT. ED., vol. 41, 2002, pages 3036
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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