Title:
NOVEL CINNAMIC ACID DERIVATIVE AND ANTIBACTERIAL COMPOSITION COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2020/122341
Kind Code:
A1
Abstract:
The present invention relates to a novel cinnamic acid derivative having an excellent antibacterial effect and an antibacterial composition comprising same. Specifically, the present invention relates to an antibacterial composition comprising a cinnamic acid derivative having antibacterial activity against bacteria contaminating cosmetic products and, more specifically, to an antibacterial composition comprising a cinnamic acid derivative as an active ingredient against microorganisms contaminating cosmetic products and a cosmetic composition comprising same. The cinnamic acid derivative exhibits a broad spectrum of antibacterial activities against various bacteria and thus, the antibacterial composition comprising same can be advantageously used for sterile, antibacterial, and antiseptic purposes in various fields such as cosmetic products, medicines, daily supplies, agricultural chemicals, etc.
Inventors:
HONG SEUNG-HEE (KR)
LEE EUN-TAEK (KR)
LEE EUN-TAEK (KR)
Application Number:
PCT/KR2019/008592
Publication Date:
June 18, 2020
Filing Date:
July 11, 2019
Export Citation:
Assignee:
LG HOUSEHOLD & HEALTH CARE LTD (KR)
International Classes:
C07D295/10; A01N43/54; A01N43/76; A23L3/3544; A61K8/49; A61K31/495; A61K31/5375; A61P31/04; A61Q17/00; C07D317/60
Domestic Patent References:
| WO2009031202A1 | 2009-03-12 |
Foreign References:
| US20060094874A1 | 2006-05-04 |
Other References:
DATABASE Registry 21 February 2003 (2003-02-21), retrieved from STN Database accession no. RN 493023-13-5
QUESADA-ROMERO, L.: "Optimal graph-based and Simplified Molecular Input Line Entry System-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as sigma1 receptor ligands", JOURNAL OF CHEMOMETRICS, 2015, pages 13 - 20, XP055717807
FREGNAN, A. M.: "Synthesis of piplartine analogs and preliminary findings on structure-antimicrobial activity relationship", MEDICINAL CHEMISTRY RESEARCH, 2017, pages 603 - 614, XP036150906, DOI: 10.1007/s00044-016-1774-9
JASZAY, Z. M.: "Preparation of esters and amines from carboxylic acids by activation with dialkyl phosphite-carbon tetrachloride mixture", SYNTHETIC COMMUNICATIONS, 1998, pages 2761 - 2768, XP055717808
LI, X.: "Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, pages 32 - 41, XP029171147, DOI: 10.1016/j.ejmech.2015.04.048
QUESADA-ROMERO, L.: "Optimal graph-based and Simplified Molecular Input Line Entry System-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as sigma1 receptor ligands", JOURNAL OF CHEMOMETRICS, 2015, pages 13 - 20, XP055717807
FREGNAN, A. M.: "Synthesis of piplartine analogs and preliminary findings on structure-antimicrobial activity relationship", MEDICINAL CHEMISTRY RESEARCH, 2017, pages 603 - 614, XP036150906, DOI: 10.1007/s00044-016-1774-9
JASZAY, Z. M.: "Preparation of esters and amines from carboxylic acids by activation with dialkyl phosphite-carbon tetrachloride mixture", SYNTHETIC COMMUNICATIONS, 1998, pages 2761 - 2768, XP055717808
LI, X.: "Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, pages 32 - 41, XP029171147, DOI: 10.1016/j.ejmech.2015.04.048
Attorney, Agent or Firm:
PHIL & ONZI INT'L PATENT & LAW FIRM (KR)
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