Title:
NOVEL COMPOUND DERIVED FROM PLANT OF GENUS QUAMOCLIT AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DIABETES
Document Type and Number:
WIPO Patent Application WO/2014/189347
Kind Code:
A1
Abstract:
The present invention provides a novel compound isolated from a plant of the genus Quamoclit and a method for preparing a novel compound isolated from a plant of the genus Quamoclit through chemical synthesis, and relates to a novel compound and a composition containing the novel compound as an active ingredient for preventing or treating diabetes and diabetic complications. The compound derived from a plant of the genus Quamoclit and the composition containing the compound as an active ingredient according to the present invention have an excellent effect of promoting insulin secretion, thereby exhibiting efficacies in preventing or treating diabetes and the resulting various complications.
Inventors:
CHUNG BONG HYUN (KR)
LEE UI JIN (KR)
YI SO YEON (KR)
LEE UI JIN (KR)
YI SO YEON (KR)
Application Number:
PCT/KR2014/004682
Publication Date:
November 27, 2014
Filing Date:
May 26, 2014
Export Citation:
Assignee:
KOREA RES INST OF BIOSCIENCE (KR)
International Classes:
C07D309/10; A61K31/351; A61P3/00; A61P3/10
Foreign References:
| KR20130020544A | 2013-02-27 | |||
| KR20110095835A | 2011-08-25 | |||
| KR20120064524A | 2012-06-19 |
Other References:
SOYDAN, A. S. ET AL.: "The Evaluation of the Role of Beta-Hydroxy Fatty Acids on Chronic Inflammation and Insulin Resistance.", MEDIATORS OF INFLAMMATION., 2006, XP055070625
DEFRONZO RA ET AL., DIABETES CARE, vol. 15, 1992, pages 318
VINSON, J. A. ET AL., J. NUTRITIONAL BIOCHEMISTRY, vol. 7, 1996, pages 559 - 663
SMITH, P. R. ET AL., EUR. J. BIOCHEM., vol. 210, 1992, pages 729 - 739
BROWNLEE, M. ET AL., SCIENCES, vol. 232, 1986, pages 1629 - 1632
YOKOZAWA, T. ET AL., , J. OF TRAD. MED., vol. 18, 2001, pages 107
BROWNLEE, M. ET AL., N. ENGL. MED.,, vol. 318, 1988, pages 1315
See also references of EP 3006434A4
DEFRONZO RA ET AL., DIABETES CARE, vol. 15, 1992, pages 318
VINSON, J. A. ET AL., J. NUTRITIONAL BIOCHEMISTRY, vol. 7, 1996, pages 559 - 663
SMITH, P. R. ET AL., EUR. J. BIOCHEM., vol. 210, 1992, pages 729 - 739
BROWNLEE, M. ET AL., SCIENCES, vol. 232, 1986, pages 1629 - 1632
YOKOZAWA, T. ET AL., , J. OF TRAD. MED., vol. 18, 2001, pages 107
BROWNLEE, M. ET AL., N. ENGL. MED.,, vol. 318, 1988, pages 1315
See also references of EP 3006434A4
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
이처영 (KR)
이처영 (KR)
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