Title:
NOVEL COMPOUND FOR PHOTODYNAMIC CANCER THERAPY, COMPOSITION COMPRISING SAME, AND PHOTODYNAMIC CANCER THERAPY METHOD
Document Type and Number:
WIPO Patent Application WO/2022/169019
Kind Code:
A1
Abstract:
The present invention relates to a novel compound for photodynamic cancer therapy, a composition comprising same, and a photodynamic cancer therapy method, and more specifically to: a novel photosensitizer compound which is based on NpImidazole having a C=S functional group introduced therein; a composition and a sensor comprising same; and a photodynamic therapy method using same.
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Inventors:
LEE SONG YI (KR)
PARK JI CHUNG (KR)
PARK JI CHUNG (KR)
Application Number:
PCT/KR2021/002533
Publication Date:
August 11, 2022
Filing Date:
March 02, 2021
Export Citation:
Assignee:
NAT UNIV PUKYONG IND UNIV COOP FOUND (KR)
International Classes:
C07D471/04; A61K41/00; A61P35/00; G01N21/64
Foreign References:
| KR20200135058A | 2020-12-02 |
Other References:
PALMER JONATHAN R., WELLS KAYLEE A., YARNELL JAMES E., FAVALE JOSEPH M., CASTELLANO FELIX N.: "Visible-Light-Driven Triplet Sensitization of Polycyclic Aromatic Hydrocarbons Using Thionated Perinones", JOURNAL OF PHYSICAL CHEMISTRY LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 11, no. 13, 2 July 2020 (2020-07-02), US , pages 5092 - 5099, XP055956298, ISSN: 1948-7185, DOI: 10.1021/acs.jpclett.0c01634
HUANG TIAN-BAO; ET AL: "General synthesis of thioxo-1,8-naphthalimides via thioxo-1,8-naphthalenic anhydrides", SYNTHESIS, GEORG THIEME VERLAG, STUTTGART, DE., vol. 1999, no. 7, 1 July 1999 (1999-07-01), STUTTGART, DE. , pages 1109 - 1111, XP008095051, ISSN: 0039-7881, DOI: 10.1055/s-1999-3520
NGUYEN VAN-NGHIA, PARK SANG JUN, QI SUJIE, HA JEONGSUN, HEO SEONYE, YIM YUBIN, BAEK GAIN, LIM CHANG SU, LEE DONG JOON, KIM HWAN MY: "Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer", CHEMICAL COMMUNICATIONS, ROYAL SOCIETY OF CHEMISTRY, UK, vol. 56, no. 77, 29 September 2020 (2020-09-29), UK , pages 11489 - 11492, XP055956300, ISSN: 1359-7345, DOI: 10.1039/D0CC04644B
PHAM THANH CHUNG, HEO SEONYE, NGUYEN VAN-NGHIA, LEE MYUNG WON, YOON JUYOUNG, LEE SONGYI: "Molecular Design toward Heavy-Atom-free Photosensitizers Based on the C═S Bond and their Dual Functions in Hypoxia Photodynamic Cancer Therapy and ClO – Detection", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 13, no. 12, 31 March 2021 (2021-03-31), US , pages 13949 - 13957, XP055956302, ISSN: 1944-8244, DOI: 10.1021/acsami.0c22174
HUANG TIAN-BAO; ET AL: "General synthesis of thioxo-1,8-naphthalimides via thioxo-1,8-naphthalenic anhydrides", SYNTHESIS, GEORG THIEME VERLAG, STUTTGART, DE., vol. 1999, no. 7, 1 July 1999 (1999-07-01), STUTTGART, DE. , pages 1109 - 1111, XP008095051, ISSN: 0039-7881, DOI: 10.1055/s-1999-3520
NGUYEN VAN-NGHIA, PARK SANG JUN, QI SUJIE, HA JEONGSUN, HEO SEONYE, YIM YUBIN, BAEK GAIN, LIM CHANG SU, LEE DONG JOON, KIM HWAN MY: "Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer", CHEMICAL COMMUNICATIONS, ROYAL SOCIETY OF CHEMISTRY, UK, vol. 56, no. 77, 29 September 2020 (2020-09-29), UK , pages 11489 - 11492, XP055956300, ISSN: 1359-7345, DOI: 10.1039/D0CC04644B
PHAM THANH CHUNG, HEO SEONYE, NGUYEN VAN-NGHIA, LEE MYUNG WON, YOON JUYOUNG, LEE SONGYI: "Molecular Design toward Heavy-Atom-free Photosensitizers Based on the C═S Bond and their Dual Functions in Hypoxia Photodynamic Cancer Therapy and ClO – Detection", APPLIED MATERIALS & INTERFACES, AMERICAN CHEMICAL SOCIETY, US, vol. 13, no. 12, 31 March 2021 (2021-03-31), US , pages 13949 - 13957, XP055956302, ISSN: 1944-8244, DOI: 10.1021/acsami.0c22174
Attorney, Agent or Firm:
MUHANN PATENT & LAW FIRM (KR)
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