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Title:
NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND ANTIBIOTIC COMPOSITION COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2022/108354
Kind Code:
A1
Abstract:
The present invention provides a novel compound, a solvate thereof, a hydrate thereof, a prodrug thereof, an isomer thereof or a pharmaceutically acceptable salt thereof, a preparation method thereof, and an antibiotic composition comprising same. The novel compound of the present invention having excellent antimicrobial activity is very useful for preventing and treating a bacterial infection.

Inventors:
HWANG HEE-JONG (KR)
SON YOUNG-JIN (KR)
KIM DAHYUN (KR)
LEE JUSUK (KR)
CIUFOLINI MARCO (CA)
Application Number:
PCT/KR2021/016975
Publication Date:
May 27, 2022
Filing Date:
November 18, 2021
Export Citation:
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Assignee:
A&J SCIENCE CO LTD (KR)
International Classes:
C07D513/22; A61K31/4353; A61K31/496; A61K31/5377; A61P31/04; C07F5/02
Domestic Patent References:
WO2015063711A12015-05-07
Foreign References:
KR20040000404A2004-01-03
JP2008115165A2008-05-22
Other References:
DAVID LEFRANC; MARCO A. CIUFOLINI: "Total Synthesis and Stereochemical Assignment of Micrococcin P1", ANGEWANDTE CHEMIE, WILEY - V C H VERLAG GMBH & CO. KGAA, DE, vol. 121, no. 23, 30 April 2009 (2009-04-30), DE , pages 4262 - 4265, XP071344343, ISSN: 0044-8249, DOI: 10.1002/ange.200900621
CIUFOLINI MARCO A., LEFRANC DAVID: "Micrococcin P1: Structure, biology and synthesis", NATURAL PRODUCT REPORTS, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 27, no. 3, 1 January 2010 (2010-01-01), GB , pages 330, XP055932185, ISSN: 0265-0568, DOI: 10.1039/b919071f
BERGE ET AL., J. PHARM. SCI., vol. 66, 1977, pages 1 - 19
"Remington's Pharmaceutical Sciences", 1990, MACK PUBLISHING
"Remington: The Science and Practice of Pharmacy", 1995, MACK PUBLISHING
DONALD J. ABRAHAMED: "Burger's Medicinal Chemistry and Drug Discovery", 2001, WILEY
"Design and Application of Prodrugs", 1985, HARWOOD ACADEMIC PUBLISHERS GMFH
Attorney, Agent or Firm:
PLUS INTERNATIONAL IP LAW FIRM (KR)
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