NOVEL METHOD FOR PREPARING (2R)-2-(2-METHOXYPHENYL)-2-(OXANE-4-YLOXY)ETHANE-1-OL COMPOUND, AND INTERMEDIATE USED THEREIN

Title:

NOVEL METHOD FOR PREPARING (2R)-2-(2-METHOXYPHENYL)-2-(OXANE-4-YLOXY)ETHANE-1-OL COMPOUND, AND INTERMEDIATE USED THEREIN

Document Type and Number:

WIPO Patent Application WO/2019/066467

Kind Code:

A1

Abstract:

Provided in the present invention are: a novel method for preparing a compound of chemical formula 1, comprising a step of obtaining a compound of chemical formula 1 by performing a reduction reaction on a compound of chemical formula 2; and an intermediate used therein. According to the preparation method of the present invention, the compound of chemical formula 1, which is useful for the production of an acetyl-CoA carboxylase (ACC) inhibitor, can be mass-produced more simply and efficiently than that of a conventional method.

Inventors:

JANG WOOK (KR)
BAEK JONG OUK (KR)
KIM HEE CHEOL (KR)
HA TAE HEE (KR)

Application Number:

PCT/KR2018/011383

Publication Date:

April 04, 2019

Filing Date:

September 27, 2018

Export Citation:

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Assignee:

HANMI PHARM IND CO LTD (KR)

International Classes:

C07D309/10; A61K31/351

Domestic Patent References:

WO2013071169A1	2013-05-16
WO2013075083A1	2013-05-23
WO2017151816A1	2017-09-08
WO2018161022A1	2018-09-07
WO2013071169A1	2013-05-16
WO2014182950A1	2014-11-13
WO2014182951A1	2014-11-13

Foreign References:

JP2003146943A

2003-05-21

Other References: