Title:
NOVEL NON-HYGROSCOPIC LOW-VARIABILITY CRYSTALLINE FORM FOR TREATMENT OF HEPATITIS C
Document Type and Number:
WIPO Patent Application WO/2021/203409
Kind Code:
A1
Abstract:
A novel non-hygroscopic low-variability crystalline form for treatment of hepatitis C. The novel crystalline form T has a simple crystallization process, is easy for industrial production, and has no hygroscopicity. The use of a suitable preparation further prepared from the crystalline form T can significantly reduce the coefficient of variation of postprandial Cmax of a subject, so that the safety and effectiveness of a drug can be more reliably guaranteed.
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Inventors:
XU DAN (CN)
DONG HONGXIN (CN)
ZHENG LIKANG (CN)
CHAI YUZHU (CN)
ZHAO MINGLI (CN)
ZHU CHUNXIA (CN)
WANG HUAPING (CN)
ZHOU LI (CN)
DONG HONGXIN (CN)
ZHENG LIKANG (CN)
CHAI YUZHU (CN)
ZHAO MINGLI (CN)
ZHU CHUNXIA (CN)
WANG HUAPING (CN)
ZHOU LI (CN)
Application Number:
PCT/CN2020/084178
Publication Date:
October 14, 2021
Filing Date:
April 10, 2020
Export Citation:
Assignee:
NANJING CHIA TAI TIANQING PHARMACEUTICAL CO LTD (CN)
International Classes:
C07H19/10; A61K31/7072; A61P31/18; C07F9/6558; C07H1/06
Domestic Patent References:
| WO2016008461A1 | 2016-01-21 | |||
| WO2016038542A2 | 2016-03-17 | |||
| WO2017158624A1 | 2017-09-21 |
Foreign References:
| CN110981910A | 2020-04-10 | |||
| CN102858790A | 2013-01-02 | |||
| CN104447924A | 2015-03-25 | |||
| CN104130302A | 2014-11-05 | |||
| CN106687470A | 2017-05-17 |
Attorney, Agent or Firm:
BEIJING CHEN QUAN INTELLECTUAL PROPERTY LAW FIRM (CN)
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