BACKGROUND OF THE INVENTION Bibliographic details of the publications referred to by author in this specification are collected at the end of the description.

The rapidly increasing sophistication of recombinant DNA technology is greatly facilitating research and development in the medical and allied health fields. A particularly important area is in mammalian including human genetics and the molecular mechanisms behind some genetic abnormalities. Progress in research in this area has been hampered by the lack of a cloned nucleic acid molecule encompassing a human centromere. The identification and cloning of a human centromere will promote the development of techniques for introducing genes into eukaryotic cells and in particular mammalian including human cells and will be an important asset to gene therapy and the development of a range of genetic diagnostic tests.

The centromere is an essential structure for sister chromatid cohesion and proper chromosomal segregation during mitotic and meiotic cell divisions. The centromere of the budding yeast Saccharomyces cerevisiae has been extensively studied and shown to be contained within a relatively short DNA segment of 125 bp that is organized into an 8-bp (CDEI) and 26-bp (cDEllI) domain, separated by a 78- to 87-bp, highly AT-rich, middle (CDEII) domain (Clarke and Carbon, 1985). The centromere of the fission yeast Schizosaccharomyces pombe is considerably larger, ranging from 40 to 100 kb, and consists of a central core DNA element of 4 to 7 kb flanked on both sides by inverted repeat units (Steiner et al., 1993). Recently, the

functional DNA components of a higher eukaryotic centromere have been characterized in a minichromosome from Drosophila melanogaster and shown to consist of a 220-kb essential core DNA flanked by 200 kb of highly repeated sequences on one side (Murphy and Karpen, 1995).

The mammalian centromere, like the centromeres of all higher eukaryotes studied to date, contains a great abundance of highly repetitive, heterochromatic DNA. For example, a typical human centromere contains 2 to 4 Mb of the 171-bp a-satellite repeat (Wevrick and Willard 1989, 1991; Trowell et al., 1993), plus a smaller and more variable quantity of a 5-bp satellite III DNA (Grady et al., 1992; Trowell et al., 1993). The role of these satellite sequences is presently unclear. Transfection of a cloned 17-kb uninterrupted a-satellite array into cultured simian cells (Haaf et al, 1992) or a 120-kb a-satellite-containing YAC into human and hamster cells (Larin et al., 1994) appear to confer centromere function at the sites of integration. Other workers have analyzed rearranged Y chromosomes (Tyler-Smith et al., 1993), or dissected the centromere of the human Y chromosome with cloned telomeric DNA (Brown et al., 1994) and suggested that 150 to 200 kb of a-satellite DNA plus 300 kb of adjacent sequences are associated with human centromere function. In addition, a human X-derived minichromosome that retained 2.5 Mb of a-satellite array has been produced by telomere-associated chromosome fragmentation (Farr et al., 1995). In all these studies, it is not known whether non-a-satellite DNA sequences are embedded within the centromeric site and operate independently of, or in concert with, the a-satellite DNA.

In mammals, four constitutive centromere-binding proteins, CENP-A, CENP-B, CENP-C, and CENP-D, have been characterized to varying extents and implicated to have possible direct roles in centromere function. CENP-A, a protein localized to the outer kinetochore domain, is a centromere-specific core histone that shows sequence homology to the histone H3 protein and may serve to differentiate the centromere from the rest of the chromosome at the most fundamental level of chromatin structure - the nucleosome (Sullivan et al., 1994). CENP-B, a protein which associates with the centromeric heterochromatin through its binding to the CENP- B box motif found in primate a-satellite and mouse minor satellite DNA, probably has a role in packaging centromeric heterochromatic DNA - a role which, however, may not be indispensable since the protein is undetectable on the Y chromosome (Pluta et al., 1990) and is found on the

inactive centromeres of dicentric chromosomes (Earnshaw et al., 1989). CENP-C has been shown to be located at the inner kinetochore plate and is postulated to have an essential although yet undetermined centromere function, as seen, for example, from inhibition of mitotic progression following microinjection of anti-CENP-C antibodies into cells (Bernat et al., 1990; Tomkiel et al., 1994) and from its association with the active but not the inactive centromeres of dicentric chromosomes (Earnshaw et al., 1989; Page et al., 1995; Sullivan and Schwartz, 1995). Finally, CENP-D (or RCC1) is a guanine exchange factor that appears to have a general cellular role that is neither specific nor clear for the centromere (Kingwell and Rattner 1987; Bischoff et al., 1990; Dasso, 1993). More recently, a new role for the mammalian centromere as a "marshalling station" for a host of "passenger proteins" (such as INCENPs, MCAK, CENP- E, CENP-F, 3F3/2 antigens, and cytoplasmic dynein), has been recognized (reviewed by Earnshaw and Mackay, 1994, and Pluta et al., 1995). These passenger proteins, whose appearance at the centromere is transient and tightly regulated by the cell cycle, provide vital functions that include motor movement of chromosomes, modulation of spindle dynamics, nuclear organization, intercellular bridge structure and function, sister chromatid cohesion and release, and cytokinesis. At present, except for CENP-B, none of the constitutive or passenger proteins have been demonstrated to bind mammalian centromere DNA directly.

In work leading up to the present invention, the inventors identified in a patient (hereinafter referred to as "BE") an unusual human marker chromosome, mardel 10, which is 100% stable in mitotic division both in patient BE and in established fibroblast and transformed lymphoblast cultures. In accordance with the present invention, a region of the mardel (10) chromosome has been cloned together with the corresponding region from a normal human subject. The nucleic acid molecules cloned contain no substantial a-satellite repeats yet are mitotically stable. The nucleic acid molecules encompass therefore, a new form of centromere referred to herein as a "neocentromere". The identification and cloning of a eukaryotic neocentromere without substantial a-satellite DNA repeat sequences now provides the means of generating a range of eukaryotic artificial chromosomes such as mammalian including human artificial chromosomes with uses in genetic therapy, transgenic plant and animal production and recombinant protein production. A range of diagnostic reagents is now also obtainable using the cloned neocentromere.

SUMMARY OF THE INVENTION Sequence Identity Numbers (SEQ ID NOs.) for the nucleotide sequences referred to in the specification are defined following the bibliography.

Throughout this specification and the claims which follow, unless the context requires otherwise, the word "comprise", or variations such as "comprises" or "comprising", will be understood to imply the inclusion of a stated integer or group of integers but not the exclusion of any other integer or group of integers.

A fibroblast cell line 920158 carrying the mardel marker chromosome was deposited at the European Collection of Cell Cultures (ECACC), Centre for Applied Microbiology Research, Salisbury, Wiltshire, SP4 OJG, UK on 1 May, 1997 under Accession No. 97051716. Bacterial artificial chromosomes (BACs) carrying portions of the mardel (10) chromosome have also been deposited at ECACC as follows: BAC/E8-1: deposited on 5 May 1998 under Accession Number 980505016; BAC/F2-14: deposited on 5 May 1998 under Accession Number 980505017.

A number of human fibrosarcoma cell lines carrying various neocentromeric constructs were deposited at ECACC as described hereafter by Accession Number with the date of deposit in parenthesises.

HT-38 98050704 (7 May 1998) HT-47 98050705 (7 May 1998) HT-54 98050706 (7 May 1998) HT-190 98050707 (7 May 1998) HT-191 98050708 (7 May 1998).

One aspect of the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides derived from a eukaryotic chromosome and encompassing a

neocentromere or a functional derivative synthetic or hybrid form thereof which nucleic acid molecule or its derivatives, synthetic forms or hybrid forms when introduced into a compatible cell is capable of replicating, acting as an extra-chromosomal element and segregating with cell division.

Another aspect of the present invention contemplates a nucleic acid molecule or its chemical equivalent having a tertiary structure which defines a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian or non- mammalian homologue.

Yet a further aspect of the present invention is directed to an isolated nucleic acid molecule comprising a sequence of nucleotides encompassing a neocentromere derived from a eukaryotic chromosome, which nucleic acid molecule when introduced into a compatible cell is a replicating, extra-chromosomal element which segregates with cell division.

Still another aspect of the present invention is directed to an isolated nucleic acid molecule having a sequence of nucleotides or their chemical equivalents which directs a conformation defining a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or a mammalian or non-rnan homologue thereof wherein the neocentromere associates with centromere binding proteins (CENP) -A and CENP-C or antibodies thereto and does not contain substantial a-satellite DNA repeat sequences.

A further aspect of the present invention is directed to an isolated nucleic acid molecule comprising a nucleotide sequence encompassing a neocentromere or a functional derivative, synthetic or hybrid form thereof which when said nucleic acid molecule is in linear form and co- introduced into a cell together with a telomeric sequence, is capable of replicating, remaining as an extra-chromosomal element and segregates with cell division.

Another aspect of the present invention provides an isolated nucleic acid molecule or a derivative, synthetic or hybrid form thereof comprising a sequence of nucleotides: (i) which directs conformation defining a human neocentromere or a functional derivative

thereof or a latent, synthetic or hybrid form thereof or its mammalian or non-mammalian homologue wherein said neocentromere is capable of associating with CENP-A and CENP-C; (ii) which contains no substantial a-satellite DNA sequence repeat; and (iii) which is capable, when introduced into compatible cells, of replication, remaining extra- chromosomal and segregating with cell division.

Even yet another aspect of the present invention is directed to a genetic construct comprising an origin of replication for a eukaryotic cell and a nucleic acid molecule encompassing a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian or non-mammalian homologue flanked by telomeric nucleotide sequences functional in the cell in which the genetic construct is to replicate and wherein said genetic construct when introduced into a cell is a replicating, extra-chromosomal element which segregates with cell division.

Another aspect of the present invention is directed to a genetic construct in the form of a eukaryotic artificial chromosome such as a mammalian artificial chromosome (MAC), a human artificial chromosome (HAC) or comprising an origin of replication and a sequence of nucleotides which: (i) directs a conformation defining a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof wherein said neocentromere is capable of associating with CENP-A and CENP-C or antibodies thereto; and (ii) contains no substantial a-satellite DNA repeat sequences; said sequence of nucleotides flanked by eukaryotic (e.g. mammalian) telomeric sequences which are in turn flanked by yeast telomeric sequences wherein a unique enzyme site is located between the human and yeast telomeric nucleotide sequences such that upon contact with said enzyme, the yeast telomeric sequences are removed and the eukaryotic (e.g. mammalian) telomeric sequences are exposed.

Still another aspect of the present invention provides a genetic construct comprising an origin of replication and a first nucleic acid molecule defining a human neocentromere or a functional

derivative thereof or latent, synthetic or hybrid form thereof, a second nucleic acid molecule encoding a peptide, polypeptide or protein, wherein said first and second nucleic acid molecules are flanked by a first set of eukaryotic (e.g. mammalian, such as human) telomeric sequences which are in turn flanked by a second set of eukaryotic (e.g. yeast) telomeric sequences wherein there are unique enzyme sites between the first and second telomeric sequences such that upon contact with a required enzyme, the second telomeric sequences are cleaved off to expose the first telomeric sequences.

BRIEF DESCRIPTION OF THE FIGURES Figure 1 is a schematic representation showing identification of a YAC contig spanning the marker centromere region. (A) Comparison of GTL banding patterns of mardel 10 and normal chromosome 10. The pair of open arrows indicate the two breakpoints on a normal chromosome 10 in generating the marker chromosome (Voullaire et al., 1993). The long and short arms of the marker chromosome are designated q' and p', respectively, to distinguish them from the q and p arms of the normal chromosome 10. Asterisk denotes the position of a cosmid 10pC38 that was used to "tag" the q'-arm of stretched marker chromosomes in the ANTI-CEN/FISH experiments. (B) A 4-megabase YAC contig (#082) from 10q25.2 region that spans the marker centromere. The tilling path of YACs #0 to #23 and their corresponding CEPH library addresses are shown. (C) FISH mapping of selected YAC clones from contig #082 using normal fluorescence microscopy and standard metaphase chromosomes prepared from transformed lymphoblast cells of patient BE. The distribution of FISH signals (vertical axis) is shown as a percentage of the signals on one arm of the marker chromosome that is in excess of those found on the opposite arm of the chromosome. The total number of fluorescence signals scored for each of the YAC clones is indicated in brackets.

Figure 2 is a photographic representation showing ANTI-CEN/FISH analysis of the marker centromere. (A) Detection of a-satellite DNA using a mixture of a-satellite DNA probes (red signals) under low stringency conditions. Centromeres were counter-labelled with CREST#6 autoimmune antibody (pale blue dots; or white when superimposed on a red background).

Chromosomes were prepared from transformed lymphoblast cells of patient BE. The right-hand

panel represents green pseudo-coloring of DAPI images of chromosomes to provide a better definition of chromosome outline. Only the signal for the antibody, but not that for a-satellite, was seen on the marker centromere (arrowed). (B) Simultaneous labelling of stretched human metaphase chromosomes with CREST#6 (red) and anti-CENP-C antibody, Am-C 1 (pale blue), with the white color indicating full coincidence of the two antibody signals. (C) Detection of CENP-C on the marker chromosome. Simultaneous labelling of the marker chromosome (arrowhead) with (a) Am-C1 (pale blue) and (b) CREST#6 (red). (c) Combined images of a and b, showing complete coincidence of Am-C1 and CREST#6 signals. (d) FISH analysis of the same cell as a-c using the 10pC38 cosmid probe (pale blue dots and green arrows) to identify the marker chromosome. Some loss of ANTI-CEN signal, especially for the Am-C 1 antibody was seen following FISH. (e) Green pseudo-coloring of DAPI images. A colour photograph corresponding to this figure is available upon request.

Figure 3 is a photographic representation showing ANTI-CEN/FISH analysis of cosmid clones on stretched (A, a-f) and superstretched (B) metaphase chromosomes. (a-c) Examples of cosmid signals (white arrows) localized to the q'-region of the marker centromere. (d-f) Examples of cosmid signals (white arrows) localized to the p'-region of the marker centromere. Green arrows indicate positions of the 10pC38 cosmid DNA tag used to mark the q'-end of the marker chromosome. (B) Mapping of Y6C21 onto a superstretched metaphase chromosome. Not included is the 10pC38 q'-tag signal located further to the left of the chromosomal segment shown. ANTI-CEN signals are in red, FISH signals are in pale blue, and overlapping ANTI-CEN and FISH signals are in white. Each of the pictures is accompanied by DAPI images of chromosomes pseudo-coloured in green. A colour photograph corresponding to this figure is available upon request.

Figure 4 Localization of the anti-centromere antibody-binding domain. a, Relative positions of different cosmid and PAC clones within the YAC #082 contig, using YAC-3 as a reference.

Cosmids are designated as YnCm, where 'n' denotes the YAC of origin and 'm' denotes the cosmid number. PACs 1-5 are five different PAC clones isolated from a human PAC library (Genome Systems Inc). "HC-contig" represents a group of overlapping cosmids that map tightly around the marker centromere in ANTI-CEN/FISH experiments. A genomic map corresponding

to the depicted YAC region was derived from the DNA of patient BE and shown above the YAC map. S, SalI; K, KspI; N, NotI; Sf, SfiI. b, Cumulative scoring of FISH signals in ANTI- CEN/FISH experiments for cosmids Y3C64, Y6C8, Y3C94, Y7C14, Y4C45, Y6C10, Y6C21, Y3C3, PAC5, Y13C1, Y13C8, and Y17C6. The distribution of FISH signals (vertical axis) is those found on the opposite arm of the chromosome. The total number of fluorescence signals scored for each of the cosmid clones is indicated in brackets. c, Restriction mapping of the 80-kb region covered by the eight overlapping cosmids of the HC-contig. These eight cosmids were derived from four different YACs (YAC-3, YAC-4, YAC-6, and YAC-7) and provided independent confirmation of the map. Furthermore, the map agreed fully with the restriction map of a 120 kb-insert PAC clone (PAC4) that spanned the entire HC-contig region. E, EcoRI; R, EcoRV; N, Note.

Figure 5 is a representation showing restriction analysis of genomic DNA of patient BE and those of his normal parents using Y6C10 as probe. DNA was resolved on a PFGE (A) or standard agarose gel (B and C). Samples 1, 2 and 3 were fibroblast cultures of mother of BE, father of BE, and patient BE, respectively. Sample 4 was a somatic hybrid cell line BE2C 1-18-SF containing the marker chromosome. Fragment sizes are in kilobases.

Figure 6 is a representation of the full nucleotide sequence of the HC-contig DNA derived from normal human chromosome 10q 25.2 region.

Figure 7 is a diagrammatic representation of the method used to retrofit YAC3 and YACS.

Figures 8A to J are diagrammatic representations of the different vectors used for cloning DNA as YACs by the conventional restriction/ligation methods.

Figures 9 is a diagrammatic representation of circular TAR summarising the recombination process.

Figure 10 is a diagrammatic representation showing modification of TAR vector.

Figure 11 is a diagrammatic representation of the cloning of 10q25 human neocentromere DNA from mardel (10) chromosome. This DNA is designated NC-contig DNA to distinguish it from the HC-contig derived from the corresponding region of the normal chromosome 10.

(A) Structural map of the NC-contig region and flanking DNA. Arrows indicate the relative positions and directions of primers used in PCR analyses (Table 3). The restriction sites EcoRI, EcoRV, Sift, and SftI and SftI are indicated by E, R, Sr and Sf, respectively. The position of the TAR "hook" CE-F2 is represented by the solid box. The hatched bar represents HC- or NC- contig. p' and q' refer to the short and long arms of mardel (10), respectively. (B) Circular TAR strategy using the vectors pVC39-Alu/C3-F2(+) and pVC39-Alu/C3-F2(-) for the direct cloning of the neocentromere DNA from mardel (10). The position of the Alu consensus sequence hook is represented by the white box. Crosses denote the sites of recombination between the TAR vector and the genomic DNA at the Alu and C3-F2 hooks during cloning.

(C) Structural maps of the resulting circular YACs 5f-52-E8 and 5f-38-F2 containing the neocentromere DNA of the mardel (10) chromosome. The DNA flanking the NC-contig is represented by stippled bars. (D) Structural maps of BAC/E8-1 and BAC/F2-14. Nt represents NotI and URA-BAC-neo represents the retrofitting vector BRV1 (Larionov et al., 1997).

Figure 12 is a diagrammatic representation showing specific TAR of HC-region from mardel 10.

The method was as follows: (1) Co-transformation into YPH857; (2) Select HIS+ colonies; (3) screen for HC-region by PCR; (4) Prepare high-MW DNA; (5) Digest with I-Scel to expose hTELS; (6) Transfect HT 1080 cells; (7) Select for G418R; and (8) analyse by PFGE and FISH.

Figure 13 is a diagrammatic representation showing cloning in yeast as YAC/HAC.

Figure 14 is a diagrammatic representation outlining TACT procedure.

Figure 15 is a diagrammatic representation of TACT constructs.

Figure 16A is a representation of the full nucleotide sequence of the NC-contig DNA derived

from mardel (10) and corresponds to the HC-contig DNA region of the normal chromosome 10.

Figure 16B is a representation of the partial nucleotide sequence of the BAC/F2-14 clone that is derived from a region immediately p' of the NC-contig DNA (see Fig. 1 lD).

SUMMARY OF SEQ ID NOs.

SEQ ID NO. DESCRIPTION 1 DNA primer 2 DNA primer 3 Nucleotide sequence of HC-contig 4 Nucleotide sequence of NC-contig 5 BAC-F2 contig 1 6 BAC-F2 contig 2 7 BAC-F2 contig 3 8 BAC-F2 contig 4 9 BAC-F2 contig 5 10 BAC-F2 contig 6 11 BAC-F2 contig 7 12 BAC-F2 contig 8 13 BAC-F2 contig 9 14 BAC-F2 contig 15 15 BAC-F2 contig 33 16 BAC-F2 contig 39 17 BAC-F2 contig 41 18 BAC-F2 contig 42 19 BAC-F2 contig 44 20 BAC-F2 contig 47 21 BAC-F2 contig 47 fragment 1 22 BAC-F2 contig 47 fragment 2 23 BAC-F2 contig 47 fragment 3 24 BAC-F2 contig 47 fragment 4 25 BAC-F2 contig 47 fragment 5 26 BAC-F2 contig 47 fragment 6

27 BAC-F2 contig 47 fragment 7 28 BAC-F2 contig 47 fragment 8 29 BAC-F2 contig 47 fragment 9 ABBREVIATIONS USED IN THE SUBJECT SPECIFICATION mardel (10): Marker chromosome from patient BE; comprises a rearrangement of chromosome 10.

HAC: Human artificial chromosome YAC: Yeast artificial chromosome MAC: Bacterial artificial chromosome PLAC: Plant artificial chromosome neocentromere: A centromere containing no substantial a-satellite DNA CENP: Centromere binding protein HC-contig: Region of normal chromosome 10 comprising neocentromere E8: q' end/region of mardel (10) neocentromere F2: p' end/region of mardel (10) neocentromere BE: Patient from which mardel (10) identified TAR: Transformation-associated recombinant PCR: Polymerase chain reaction Marker neocentromere: neocentromere on mardel (10).

NC-contig region of mardel (10) chromosome comprising neocentromere DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS The present invention is predicated in part on the identification and isolation of nucleic acid molecules exhibiting neocentromeric properties. In accordance with the present invention, a neocentromere is considered a centromere which does not contain substantial a-satellite DNA repeat sequences and, when activated, is capable of functioning as a centromere. The term

"substantial" in this context means that the nucleic acid molecule does not contain detectable a-satellite by FISH analysis under medium stringency conditions. The neocentromere may contain a small number of highly diversed a-satellite DNA. In primates, a-satellite DNA is consider 17lbph in length. An nucleic acid molecule containing an activated neocentromere or a neocentromere otherwise functioning as a centromere facilitates in accordance with the present invention, the nucleic acid molecule replicating, remaining extra-chromosomal and segregating with cell division. Reference herein to "neocentromere" is taken to mean a centromere substantially devoid of a-satellite DNA repeat sequences.

Accordingly, one aspect of the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides which defines an eukaryotic neocentromere.

More particularly the present invention provides an isolated nucleic acid molecule comprising a sequence of nucleotides derived from a eukaryotic chromosome and encompassing a neocentromere which nucleic acid molecule when introduced into a compatible cell is capable of replicating, acting as an extra-chromosomal element and segregating with cell division.

The present invention is exemplified herein by the identification and cloning of a human neocentromere. This is done, however, with the understanding that the present invention extends to all eukaryotic neocentromeres such as from mammalian, plant, aviary, insect, fungal, yeast and reptilian chromosomes. The most preferred neocentromere, however, is from human chromosomes and their mammalian homologues.

The present invention is predicated in part on the identification of an unusual chromosomal marker in a patient designated "BE". The chromosomal marker is referred to as "mardel (10)" and results from a rearrangement of human chromosome 10. The mardel (10) marker is mitotically stable and, in accordance with the present invention, contains a functional neocentromere at a location regarded as non-centromeric. The neocentromere at mardel (10) is located between q24 and q26 on chromosome 10 and more particularly around q25. Even more particularly, the neocentromere maps to q25.2 on chromosome 10. The present invention is exemplified by DNA cloned from the q24-q26 region of the mardel (10) chromosome as well

as the corresponding region on normal human chromosome 10. These DNA molecules contain a functional neocentromere. The present invention extends, however, to any neocentromere or any chromosome in mammalian and non-mammalian animals as well as plants, yeasts and fungi.

For convenience, the DNA clones from the mardel (10) chromosome as well as from normal human chromosome 10 are summarised in Figure 11. The neocentromere located at or around 10q25 is located on a clone designated the "HC-contig". DNA clones from mardel (10) are referred to as "E8" or the "NC-contig" which extends from the long arm (q') of mardel (10) towards the short arm (p'). Clone F2 extends further p' from E8 (see Figure 11). It is emphasised, however, that the present invention extends to any neocentromere on any human chromosome as well as neocentromeres on other mammalian and non-mammalian chromosomes including chromosomes from plants, insects, reptiles, yeast and fungi.

The present invention further contemplates a nucleic acid molecule or its chemical equivalent having a tertiary structure which defines a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian or non-mammalian homologue.

Even more particularly, the present invention is directed to an isolated nucleic acid molecule having a sequence of nucleotides or their chemical equivalents which directs a conformation defining a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian or non-manmalian homologue wherein the centromere associates with centromere binding proteins (CENP) -A and CENP-C or antibodies thereto.

Reference herein to "latent" in relation to a centromere includes reference to a centromere not normally functional but nevertheless activatable under certain conditions. A latent centromere may also be considered as a neocentromere provided it has no substantial a-satellite DNA repeat sequences.

The size of the neocentromere in accordance with the present invention may range from about

50 bp to about 1500 kbp, from about 70 bp to about 1000 kbp, from about 75bp to about 800 kpb, from about 80 bp to about 500 kbp, from about 85 bp to about 200 kbp, from about 90 bp to about 100 kbp, from about 100 bp to about 1 kbp, about 120 bp to about 500 bp, about 180 bp to about 300 bp. In one particular embodiment, the centromere is approximately 60-100 kbp.

In another embodiment, the centromere is about 80 kbp.

The nucleic acid molecule encompassing the HC-contig for human chromosome 10 of the present invention set forth in Figure 6 (SEQ ID NO: 3). The nucleic acid molecule encompassing the NC-contig (part of E8) from mardel (10) is set forth in Figure 16A (SEQ ID NO: 4). The nucleic acid molecule encompassing F2 of mardel (10) is set forth in Figure 16B as separate contigs (SEQ ID NOs: 5-29). The nucleic acid molecules have a tertiary structure and the neocentromere is a conformation of nucleotides within this tertiary structure.

Accordingly, the neocentromere is not defined by a linear sequence of nucleotides although this linear sequence directs the conformation which in turn defines the neocentromere. Although this aspect of the present invention is exemplified using the nucleotide sequence set forth in Figure 6, 16A and 16B, the subject invention extends to any sequence directing a conformation defining a centromere and hybridising to the sequence set forth in one or more of Figures 6, 16A and/or 16B under low stringency conditions at 42"C and/or which comprises a nucleotide sequence having at least about 40% nucleotide similarity to one or more sequences set forth in Figures 6, 1 6A and/or 16B. Preferably, the percentage similarity is at least about 50%, more preferably at least about 60%, still more preferably at least about 70%, even more preferably at least about 80-90% or above such as 95%, 97%, 98% and 99%.

Another embodiment of the present invention is directed to YAC 3 and YAC 5 encompassing the HC contig and flanking sequence as well as nucleotide sequences related to YAC 3 and/or YAC 5 at the homology, similarity or hybridization levels.

Reference herein to a low stringency at 42"C includes and encompasses from at least about 1% v/v to at least about 15% v/v formamide and from at least about 1M to at least about 2M salt for hybridisation, and at least about 1M to at least about 2M salt for washing conditions. Alternative stringency conditions may be applied where necessary, such as medium stringency, which

includes and encompasses from at least about 16% v/v to at least about 30% v/v formamide and from at least about 0.5M to at least about 0.9M salt for hybridisation, and at least about 0.5M to at least about 0.9M salt for washing conditions, or high stringency, which includes and encompasses from at least about 31% v/v to at least about 50% v/v formamide and from at least about 0.01M to at least about 0. 15M salt for hybridisation, and at least about 0.01M to at least about 0. 15M salt for washing conditions. These stringency conditions may be altered dependent on the source of DNA and other factors.

The term "similarity" as used herein includes exact identity between compared sequences at the nucleotide level. Where there is non-identity at the nucleotide level, "similarity" includes differences between sequences which nevertheless result in conformation defining a functional neocentromere.

The nucleic acid molecule of the present invention may comprise a naturally occurring nucleotide sequence from a healthy human subject or may comprise the nucleotide sequence from a human subject exhibiting one or more chromosomal-dependent conditions such as a subject carrying mardel 10 chromosome or a chromosome conferring an equivalent or similar condition or may carry one or more nucleotide substitutions, deletions and/or additions relative to the naturally or non-naturally occurring sequence. Such modifications are referred to herein as "derivatives" and include mutants, fragments, parts, homologues and analogues of the naturally occurring nucleotide sequence. Preferably, the derivatives of the present invention still define a functional neocentromere.

Reference herein to a "neocentromere" includes reference to a functional neocentromere or a functional derivative thereof meaning that it is capable of facilitating sister chromatid cohesion and chromosomal segregation during mitotic cell divisions and/or is capable of associating with CENP-A and/or CENP-C and/or is capable of interacting with anti-CENP-A antibodies or anti- CENP-C antibodies. Generally, and prelerably, the neocentromere is incapable of interacting with CENP-B or anti-CEP-B antibodies. Alternatively, the neocentromere may be a latent centromere capable of activation by epigenetic mechanisms. The neocentromere may also be a hybrid of other human, mammalian, plant or yeast neocentromeres. Synthetic neocentromeres

provided by, for example, polymeric techniques to arrive at the correct confromation are also contemplated by the present invention. All such forms and definitions of neocentromere are encompassed by use of this term.

Another aspect of the present invention provides an isolated nucleic acid molecule or chemical equivalent having the following characteristics: (i) comprises a nucleotide sequence or chemical equivalent directing a conformation which defines a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or; (ii) comprises a nucleotide sequence or chemical equivalent substantially as set forth in one or more of Figures 6, 16A and/ or 16B or having at least about 40% similarity thereto or capable of hybridising thereto under low stringency conditions at 420C; and (iii) comprises a neocentromere capable of associating with CENP-A or CENP-C or antibodies thereto.

Preferably, the neocentromere is incapable of interacting with CENP-B or antibodies thereto.

In a particularly preferred embodiment, the centromere corresponds to a human genomic region which maps between q24 and q26 on chromosome 10, and in particular q25 on chromosome 10.

The nucleic acid molecule or its chemical equivalent of the present invention defining a conformational neocentromere or functional derivative thereof or latent, synthetic or hybrid form thereof is useful inter alia for the generation of artificial chromosomes such as human artificial chromosomes (HACs), mammalian artificial chromosomes (MACs), yeast artificial chromosomes (YACs) and plant artificial chromosomes (PLACs). HACs are particularly useful since they are capable of accommodating large amounts of DNA and are capable of propagation in human cells.

The HACs are non-viral in origin and, hence, are more suitable for gene therapy by, for example, introducing therapeutic genes. Furthermore, the HACs remain extra-chromosomal and, hence, have no insertional/substitutional mutagenic potential. The essence of a HAC is the presence of a neocentromere or latent, synthetic or hybrid form thereof which enables stable segregation during cell division. The HAC also remains extra-chromosomal and, hence, is more suitable for

gene therapy. Reference to "extra-chromosomal" means that it does not integrate into the main chromosome and, in effect, is episomal.

Accordingly, the present invention provides a genetic construct comprising an origin of replication for a eukaryotic cell and a nucleic acid molecule encompassing a eukaryotic neocentromere or a functional derivative thereof or a latent, synthetic, hybrid form thereof or its mammalian or non-mammalian homologue flanked by telomeric nucleotide sequences functional in the cell in which the genetic construct is to replicate and wherein said genetic construct when introduced into a cell is a replicating, extra-chromosomal element which segregates with cell division.

More particularly, the present invention further contemplates a genetic construct in the form of an artificial chromosome comprising an origin of replication for a mammalian, human, plant or yeast cell and a nucleic acid molecule encompassing a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian or non-mammalian homologue flanked by telomeric nucleotide sequences functional in the cell in which the artificial chromosome is to replicate.

Another embodiment provides a genetic construct in the form of an artificial chromosome comprising an origin of replication for a mammalian, human, plant or yeast cell and a nucleic acid molecule having a tertiary structure which defines a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or its mammalian homologue flanked by telomeric sequences functional in the cell in which the artificial chromosome is to replicate.

Yet another embodiment is directed to a genetic construct in the form of an artificial chromosome comprising an origin of replication for a mammalian, human, plant or yeast cell and a nucleic acid molecule having a sequence of nucleotides which directs a conformation defining a human neocentromere wherein the centromere associates with CENP-A and/or CENP-C or antibodies thereto and does not contain substantial a-satellite DNA repeat sequences, said nucleic acid molecule flanked by telomeric nucleotide sequences functional in the cell which the

artificial chromosome is to replicate.

Still yet another aspect of the present invention relates to a genetic construct in the form of an artificial chromosome comprising an origin of replication for a mammalian, human, plant or yeast cell and a nucleic acid molecule comprising a sequence of nucleotides which: (i) directs a conformation which defines a neocentromere or a functional form thereof or a latent, synthetic or hybrid form thereof; (ii) comprises a nucleotide sequence substantially as set forth in one or more of Figures 6, 16A and/or 16B or having at least about 40% similarity to the nucleotide sequences set forth in Figures 6, 16A and/or 16B or is capable of hybridising to one or more of these sequences under low stringency conditions at 42"C; wherein the neocentromere is capable of associating with CENP-A and/or CENP-C or antibodies thereto and wherein said nucleic acid molecule is flanked by telomeric nucleotide sequences functional in the cell in which the artificial chromosome replicates.

In a preferred embodiment, the genetic construct is a HAC and comprises human telomeric sequences. In a particularly preferred embodiment, the HAC further comprises yeast artificial chromosome (YAC) arms and, hence, becomes a HAC/YAC shuttle vector capable of propagation in human and yeast cells. Preferably, the HAC/YAC contains a unique enzyme site between yeast telomeric sequences and human telomeric sequences such that upon contact with the particular enzyme, the yeast telomeric sequences are removed leaving the human telomeric sequences. Preferably, the unique enzyme site is a yeast specific enzyme site such as I-SceI.

According to this embodiment, there is provided a genetic construct defining a HAC/YAC comprising an origin of replication and a nucleic acid molecule encompassing a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or a mammalian or non-mammalian homologue thereof, said nucleic acid molecule flanked by human telomeric sequences which are in turn flanked by yeast telomeric sequences wherein a unique enzyme site is located between the human and yeast telomeric nucleotide sequences such that upon contact with the enzyme, the yeast telomeric sequences are removed and the human telomeric sequences are exposed.

More particularly, the present invention is directed to a genetic construct defining a HACNAC comprising an origin of replication and a nucleic acid molecule encompassing a human centromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or a mammalian or non-mammalian homologue thereof wherein the neocentromere associates with CENP-A and/or -C or antibodies thereto and does not contain substantial a-satellite DNA sequences wherein said nucleic acid molecule is flanked by human telomeric sequences which are in turn flanked by yeast telomeric sequences wherein a unique enzyme site is located between the human and yeast telomeric nucleotide sequences such that upon contact with said enzyme, the yeast telomeric sequences are removed and the human telomeric sequences are exposed.

Even more particularly, the present invention is directed to a genetic construct in the form of a HAC/YAC comprising an origin of replication and a sequence of nucleotides which directs a conformation defining a human neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof or a mammalian or non-mammalian homologue thereof wherein said neocentromere is capable of associating with CENP-A and/or CENP-C or antibodies thereto, said sequence of nucleotides flanked by human telomeric sequences which are in turn flanked by yeast telomeric sequences wherein a unique enzyme site is located between the human and yeast telomeric nucleotide sequences such that upon contact with said enzyme, the yeast telomeric sequences are removed and the human telomeric sequences are exposed.

Preferably, the length of the nucleotide sequence is between about 30 kpb and 1500 kpb, and more preferably between 60 kbp and 1000 kpb.

In a particularly preferred embodiment, the unique enzyme site is a yeast specific enzyme site such as I-SceI.

The present invention extends to yeast cells and human cells carrying the genetic constructs of the present invention and to proteins produced therefrom.

The genetic constructs may also comprise marker genes and other unique restriction sites to facilitate insertion of adventitious DNA. Accordingly, the genetic constructs of the present

invention may further comprise adventitious or heterologous DNA encoding a product of interest. Preferred products of interest include pharmaceutically useful genes such as genes encoding cytokines, receptors, growth regulators and the like. Endogenous genes may also be replaced by wild-type genes or modified genes.

The adventitious or heterologous DNA may also encode a molecule not synthesised in a sufficient amount in a particular subject and hence the increased copy number permits greater amounts of the molecule being synthesised.

Accordingly, the present invention contemplates a genetic construct comprising an origin of replication and a first nucleic acid molecule defining a human neocentromere or a functional derivative thereof or latent, synthetic or hybrid form thereof or a mammalian or non-mammalian homologue, a second nucleic acid molecule encoding a peptide, polypeptide or protein, wherein said first and second nucleic acid molecules are flanked by a first set of human telomeric sequences which are in turn flanked by a second set of yeast telomeric sequences wherein there are unique enzyme sites between the human and yeast telomeric sequences such that upon contact with said enzyme, the yeast telomeric sequences are cleaved off to expose the human telomeric sequences.

Reference herein to segregate preferably means mitotically stable segregation. Conveniently, stable segregation may be determined as the presence of an artificial chromosome in 40-60% of daughter cells after 4-6 months of continuous passage.

The present invention extends to other artificial chromosome analogues to the HACs and HAC/YACs described above such as MACs and PLACs.

Another aspect of the present invention relates to peptides, polypeptides and proteins which bind, interact or otherwise associate with the human neocentromere of the present invention or its mammalian and non-mammalian homologue. Preferably, the molecules are proteins, referred to as primary (1°) proteins. The 1" proteins bind to the neocentromere and secondary (2°) proteins bind to the 1" proteins before or after association with the neocentromere. The identification

of the human neocentromere in accordance with the present invention provides a mechanism for assaying 1" proteins and 2" proteins which may be important for screening chromosomes in, for example, genetic disorders. This is particularly the use in Down's Syndrome which results from defective chromosome segregation.

The 1" proteins are readily detected by, for example, a gel shift assay. The nucleic acid molecule of the present invention defining the human neocentromere is digested, labelled and contacted with nuclear extract putatively containing the 1" proteins and resolved on a gel. When a 1" protein binds to a fragment carrying a binding portion of the neocentromere, the DNA fragment migrates in the gel at a slower rate due to the bound protein.

The present invention extends to purified 1" proteins capable of association with the subject centromere and to genetic sequences encoding same and to antibodies thereto.

The neocentromeres of the present invention are readily identified and characterised using, for example, human fibrosarcoma cell lines. For example, DNA suspect of carrying a neocentromere, is introduced into fibrosarcoma cells in a linear form, generally together with a telomeric sequence. The cells are then screened for the presence of replicating, extra- chromosomal and segregating elements, referred to as mini chromosomes.

The present invention further encompasses eukaryotic cells carrying replicating, extrachromosomal and segregation nucleic acid molecules. Preferably the eukaryotic cells are mammalian cells and most preferably human cells. The nucleic acid molecules according to this aspect of the present invention are preferably as herein described. Particularly preferred cells are HT-38, HT-47, HT-54, HT-190, HT-191, BAC/E8-l, and BAC/F2-14.

The present invention is further described by the following non-limiting Figures and Examples.

EXAMPLE 1 YAC and Cosmid Probes for FISH YACs carrying specific STSs were identified (Moir et al., 1994) by PCR-based screening of YAC libraries prepared in pYAC4 vector at the Center for Genetics in Medicine at Washington University (Brownstein et al., 1989) and at the CEPH (Albertsen et al., 1990). Cosmid DNA inserts (3540 kb) were ligated to SuperCos I vector (Stratagene) and packaged with Gigapack III Gold extract (Stratagene) according to the manufacturer's instructions. YAC probes were prepared by Alu-PCR of total yeast genomic DNA using primers 5'- GGATTACAGG(C/T)(A/G)TGAGCCA-3' [SEQ ID NO: 1] and 5'- (A/G)CCA(C/T)TGCACTGCAGCCTG-3' [SEQ ID NO:2] according to published method (Archidiacono et al., 1994). For probe labelling, 1 pg of the YAC PCR products or whole cosmid DNA isolated by CsCl centrifugation or Qiagen column was used. The DNA was labelled with Biotin-16-dUTP (Boehringer Mannheim) using a NICK translation kit (Boehinger Mannheim). A probe mix of 6-10 pg/ml of biotinylated probe DNA, 300 llg/ml of COT- 1 DNA (Boehringer Mannheim), 500 pg/ml of carrier salmon sperm DNA and, where indicated, 10 pg/ml of biotinylated 10pC38 tag DNA was ethanol precipitated, resuspended in a hybridization mix of 50% v/v formamide in 2 x SSC and 10% w/v dextran sulphate, denatured at 95"C for 5 min, preannealed for 30-60 min at 37"C to suppress repetitive sequences, before adding to slides. FISH of a-satellite and satellite III probes was performed under low stringency as previously described (Voullaire et al., 1993).

EXAMPLE 2 Somatic Cell Hybrids and Other Cell Lines Skin fibroblasts and transformed lymphoblast cell lines were established from patient BE (Voullaire et al., 1993) and from his normal parents. The presence of the mardel 10 chromosome in the patient cell lines was confirmed by FISH. In addition to these cell lines, two somatic cell hybrids were produced by fusing cultured fibroblast cells derived from patient BE with the Chinese hamster ovary cell line CHO-Kl using polyethylene glycol. Hybrid cells were selected in a proline-free medium for the glutamic oxaloacetic transaminase- 1 (GOT- 1) gene located in

10q24-q25 region. One of the hybrid cell lines, designated BE2C l - 18- f, was shown to contain the normal chromosome 10 but not the marker chromosome, while another hybrid cell line, designated BE2C 1 - 18-SF, contained the marker chromosome but not the normal chromosome 10 of patient BE. The presence or absence of these chromosomes was established by karyotyping and ANTI-CEN/FISH probing. In addition, PCR analysis of an STS (sequence tagged site) marker, AFM259xg5, which resided on YAC-3, confirmed the status of these chromosomes in the hybrids and excluded the presence of submicroscopic fragments of the marker centromere region within the genome of BE2Cl-18-lf, or the presence of the corresponding region of normal chromosome 10 within the genome of BE2C1-18-5f. Use of this STS marker also demonstrated that the mardel 10 chromosome has originated from the patient's father.

EXAMPLE 3 Antisera Antiserum CREST #6 was from a patient with Calcinosis, Baynaud's phenomenon, çsophageal dysmotility, sclerodactyly and telangiectasia (a constellation of symptoms commonly referred to as "CREST"; Moroi et al., 1981; Fritzler and Kinsella, 1980; Brenner et al., 1981). Western blot analysis of this antiserum indicated that the primary antigens detected were human CENP-A and CENP-B. A specific anti-CENP-C polyclonal antibody, designated Am-C1, was produced by the inventors by expressing a partial mouse CENP-C polypeptide (amino acid #41 to 345) as a GST- fusion product in E. coli, followed by gel purification of the product and its use as an antigen for antibody production in rabbit.

EXAMPLE 4 Preparation of Standard Metaphase Chromosomes for FISH analysis Actively replicating transformed lymphoblasts were incubated at 370C for 17 h in the presence of 0.1M final concentration of thymidine before they were centrifuged at 2000 rpm for 10 min, washed with pre-warmed RPMI, and incubated for a further 5-6 h. 15 min before harvesting, colcemid (10gg/mi) was added. Cells were harvested according to standard cytogenetic techniques using 0.075M KCl hypotonic solution for 15 min at 370C, followed by three fixative

washes in ice cold methanol/acetic acid 3:1, dropped onto clean glass slides, and stored dessicated at -200C until required.

EXAMPLE 5 Preparation of Mechanically Stretched Chromosomes for ANTI-CEN/FISH Mapping METHOD-I This is an adaptation of the method described by Page et al. (1995). Colcemid (10,ug/ml) was added to actively dividing transformed lymphoblasts for 2-3 h, before the cells were centrifuged at 1500 rpm for 10 min, washed in PBS, and resuspended in 0.075M KCl hypotonic solution for 10 min at RT at a concentration of approximately 5 x 104 cells/ml; the use of fewer cells here gave better stretching of the chromosomes. 200-300p1 of this suspension were then cytocentrifuged onto clean microscope slides using a Cytospin 2 (Shandon) at 1000 rpm for 5 min at high acceleration. The slides were immediately removed, placed flat in a shallow dish and very gently flooded with KCM (Potassium Chromosome Medium: 120 mM KCl, 20mM Nacl, 10mM Tris-HCl, 0.5mM Na2EDTA, 0.1% v/v Triton X-100) (Jeppesen et al., 1992).

After 10 min at RT, immunofluorescence was performed without fixation (Earnshaw and Migeon, 1985; Earnshaw et al., 1989; Jeppesen et al., 1992; Jeppesen and Turner, 1993). KCM buffer was gently aspirated and 501l1 of CREST#6 serum [diluted 1:50 in 1 x TEEN (lmM Triethanolamine HCl, 0.2 mM Na2EDTA, 25 mM NaCl), 0.1% v/v Triton X-100, 0.1% w/v BSA] was added to the cell area of the slide and covered with a parafilm coverslip. The slides were incubated for 30 min at 370C, then washed very gently by flooding in 1 x KB [10 mM Tris-HCl (pH7.7), 0.15M NaCl, 0.1% w/v BSA), three rinses of 3 min each at RT. The primary antibody was detected with Texas Red-conjugated Affini-pure Rabbit anti-Human IgG (H&L) (Jackson Laboratories) diluted 1:50 in 1 x KB-. 50 al was added to each slide, covered with a parafilm coverslip, and incubated for 30 min at 37"C. The slides were again gently washed by flooding in 1 x KB for 2 min at RT, before they were fixed by flooding in 10% v/v formalin in KCM for 10 min at RT, followed by three rinses of 3 min each in distilled water. If FISH was not performed the slides were rinsed in PBS and mounted in DAP1 (0.25 ,ug/ml) in DABCO antifade mountant. [In experiments where CREST#6 and Am-C1 antisera were simultaneously used to label the centromere (Figs. 2B and C), the above procedure was

followed except for the addition of Am-Cl diluted 1:100 together with CREST#6, and the Am- Cl antibody was detected using 1:100 diluted Donkey anti-Rabbit DTAF (Jackson Laboratories)].

If FISH was to be performed on the slides, they were then given a second fix in 3:1 methanol/acetic acid for 15 min at RT. The slides were air dried for at least 5 min and either processed for FISH or stored at -200C for up to several days before continuing. For FISH, the slides were dehydrated at RT in 70%, 90%, 100% v/v ethanol (2 min each) and air dried.

Chromosomal DNA was denaturated in deionised 70% v/v formamide/2xSSC, pH 7.0 at 820C for 8 min followed by immediate dehydration in 70%, 90% and 100% v/v ethanol at -20°C for 2 min each, then air dried for at least 10 min. (This high temperature of denaturation was critical to obtain maximum FISH signals). An amount of 15 Crl of the prepared probe was added to each slide, covered with a 22mm2 coverslip, and sealed with rubber cement. Slides were hybridized overnight in a humid chamber at 370C, then rinsed in 2 x SSC at RT, followed by 3 washes of 0. l x SSC at 60"C for 5 min each, rinsed again in 2 x SSC, and immersed in a blocking agent of 5% non fat milk in 4 x SSC for 10 min at RT. Probe hybridization was detected by incubation with FITC-conjugated avidin at 370C for 30 min, followed by three washes of 5 min each at RT in wash buffer (4 x SSC, 0.05% v/v Tween-20). Signals were amplified by incubating with goat anti-avidin D antibodies for 30 min at 370C, followed by three washes of 5 min each at RT in wash buffer, then with another layer of avidin-FITC for 30 min at 370C, before the slides were washed in wash buffer, rinsed in PBS, and counter- stained with DAPl (0.25 llg/ml) in DABCO mountant.

METHOD -11 The following method was modified from that of Haaf and Ward, (1994). Actively dividing lymphoblast cells were treated with 10pg/ml colcemid for 2-3h, washed in PBS and resuspended in a hypotonic solution consisting of 10mM Hepes (pH7.3), 30mM glycerol, 1.0mM Cacti2 and 0.8mM MgC12, at a cell density of approx. 2.5 x 102/ml. After 10 min of hypotonic treatment at RT, 300 tI were cytocentrifuged (Shandon - Cytospin 2) onto glass slides at 800 rpm for 4 min. The slides were immediately removed from the centrifuge, dried

for 15 sec, fixed in methanol at -200C for 20-30 min, rinsed in acetone at -200C for a few sec, then washed in 3 rinses of PBS at RT. Immunofluorescence staining was done using CREST#6 at a dilution of 1:50 in PBS. After incubation at 37"C for 30 min, the slides were washed three times in PBS for 2 min each. This primary antibody was then detected by a further incubation for 30 min at 37"C with Texas Red-conjugated Rabbit anti-Human IgG diluted at 1:50 in PBS.

The slides were fixed in 10% v/v formalin in KCM for 10 min at RT, then washed in 3 rinses of distilled water and drained. Before FISH was performed, slides were fixed in methanol/acetic acid 3:1 for 15 min at RT and air dried. Chromosomal DNA was denatured in 70% v/v deionised formamide (pH7.0) in 2 x SSC at 82"C for 4-6 min. After dehydration in an ice cold ethanol series the slides were air dried, and used for FISH as described for Method I. Slides could be stored covered in foil at RT after methanol/acetic acid fix for up to several weeks before FISH.

Both methods I and II were used to obtain the results shown in Figs. 2B, 2C, 3 and 4B.

EXAMPLE 6 Image Analysis Hybridization signals for YAC mapping on standard metaphase preparations utilized a normal fluorescence microscope. Images for the ANTI-CEN/FISH experiments were analyzed on a Zeiss Axiolab fluorescence microscope equipped with a 100x objective and a cooled CCD camera (Photometrics Image Point) controlled by a Power Mac computer. Gray scale images were captured separately using a LUDL filter wheel and controller for Texas Red, FITC and DAPI. These images were pseudocoloured and merged using IPlab Spectrum software from Signal Analytics Corporation. A number of difficulties were commonly associated with the ANTI-CEN/FISH technique: (a) the deliberate "stretching" of the chromosomes, whilst increasing the resolution of mapping, sometimes caused serious distortion to the chromosomes, often making them quite dysmorphic; (b) FISH treatment following the ANTI-CEN-labelling often significantly reduced the ANTI-CEN signals; (c) more highly stretched chromosomes (which would potentially give better mapping resolution) generally gave weaker ANTI-CEN signals; and (d) the ANTI-CEN signal on the mardel 10 centromere was usually weaker than

those of the other human chromosomes. Thus, a cell would only be considered informative and used for scoring if both the p'- and q'-arms of the mardel 10 chromosome were discernible and separated by a discrete ANTI-CEN signal. In addition, FISH signals for both the test probe and the 10pC38 cosmid tag (used to identify the q'-arm of, and thus orientate, the marker chromosome) must be clearly present. Using these criteria, the overall frequency of informative cells was found to be approximately 1 in every 20-30 metaphases analyzed.

EXAMPLE 7 Restriction Analysis of Patient DNA High-molecular weight genomic DNA was extracted from cultured fibroblast cell lines of patient BE and those of his parents and digested with different enzymes to generate restriction fragments ranging from <1 kb up to 1 Mb. The digested DNA was resolved either on a standard agarose gel or by pulsed-field gel electrophoresis (PFGE) using a Bio-Rad CHEF-XA Mapper. For filter hybridization, 50-100 ng of whole cosmid or PAC DNA was labelled by random priming. The labelled probe was then added to 2 ml of hybridization buffer (0.5M Na2HPO4, 7% w/v SDS, 1% w/v BSA, lmM EDTA, pH. 7.0) containing 500 ,ug of human placental DNA (Sigma). The mixture was boiled for 5 min, then placed in a 65"C water bath for preannealing of repetitive DNA for 90 min. The preannealed probe mix was then added to prehybridizing filters and hybridized overnight at 650C. Post-hybridization washes were at a final stringency of 0.1 x SSC, 0.1% w/v SDS at 680C.

EXAMPLE 8 Identification of a YAC region spanning the marker centromere The initial search for DNA sequences spanning the centromere of the mardel 10 chromosome was based on fluorescence in situ hybridization (FISH) of existing cosmid and YAC clones (Moir et al., 1994; Zheng et al., 1994) that have been mapped to the q24 - q26 region of the normal human chromosome 10 where the new marker centromere was formed (Voullaire et al., 1993) (Fig. 1A). This search led to the identification of a 4 megabase YAC contig (designated #082) that spanned the marker centromere region (Fig 1B). Fig. 1C graphically presents the

FISH mapping results with selected YACs from this contig. As can be seen, two of the YACs (YACs-1 and YAC-2) mapped to the q'-side of the marker centromere, whereas the remaining YACs mapped to the p'-side of the centromere. The low signal level observed for YAC-3 was due to a large proportion of this probe hybridising directly on the centromere itself. These results, therefore, provided evidence that YAC contig #082 spanned the marker centromere, and that the centromere region was likely to be within YAC-3, where the "cross-over" between the q' and p' signals occurred.

EXAMPLE 9 Development of Improved ANTI-CEN/FISH Methods for the Simultaneous Detection of Marker Centromere and Single-copy Cosmid DNA Probes Although normal fluorescence microscopy and FISH analysis of standard metaphase chromosomes were adequate for the initial identification of the YAC contig spanning the marker centromere, methods with significantly higher sensitivity and resolution were needed to allow further walking into the marker centromere DNA. Three requirements have to be satisfied by these methods: (a) the metaphase chromosomes have to be extended to offer much greater mapping resolution, (b) the centromeres have to be more precisely defined than that offered by a cytogenetic constriction, and (c) the methods should allow simultaneous visualization of both the centromere antibody and FISH signal. Two published methods were explored (designated here as ANTI-CEN/FISH methods) based on extending metaphase chromosomes by mechanical stretching and labelling of the neocentromere by autoimmune antibodies (Haaf and Ward, 1994; Page et al., 1995). Since these methods were originally established for the labelling of normal centromeres and for FISH analysis of highly repeated DNA, they were modified (see Example 4) to allow detection of the generally reduced ANTI-CEN signal of the subject marker neocentromere and the lower FISH signals resulting from the use of single-copy cosmid DNA probes.

With the improved detection methods, the status of a-satellite and satellite III DNA on the marker neocentromere was reassessed, since this was previously determined using standard

microscopy and FISH (Voullaire et al., 1993). Fig. 2A shows the result of antibody labelling using CREST#6 and FISH using a-satellite DNA, and indicated the absence of detectable signal on the marker centromere. The same result was obtained when the experiments were repeated without ANTI-CEN-labelling, ruling out the possibility that the anti-centromere antibody might have obscured any weak FISH signals. Similar results were obtained with satellite III DNA.

Since in separate reconstruction experiments, it was possible to demonstrate the sensitivity of the procedure in detecting a single-copy DNA probe of less than 1.5 kb, and making the reasonable assumption that the low-stringency hybridization conditions used for the a-satellite and satellite m DNA which, by virtue of the use of >100-fold excess of probes and the strong hybridisation of these probes to all the other centromeres, would have allowed the detection of any related sequences, it can be concluded that these satellite are absent.

EXAMPLE 10 Co-localization of CENP-C and CENP-A on the Marker neocentromere To test if CENP-C is present on the marker centromere, a specific rabbit polyclonal antibody was prepared against a recombinant product of mouse CENP-C. This antibody, designated Am 1, reacted strongly with the centromeres of rodent and human chromosomes. Fig. 2B shows results for the labelling of stretched human metaphase chromosomes using this antibody simultaneously with the CREST#6 autoimmune antibody. As can be seen, irrespective of the degree of chromosome stretching, the signals for the two antibodies coincided fully on all the centromeres.

The localization of these two antibodies on the marker chromosome was further determined by employing the 10pC38 cosmid tag in an ANTI-CEN/FISH experiment to identify the marker chromosome. The results indicated that both the antibody signals were clearly present and again coincided completely on the marker centromere (Fig. 2C, a-e). Although CREST #6 was known to bind CENP-A and CENP-B, indirect evidence suggests that binding to the marker centromere presumably occurred via CENP-A since the presence of the marker centromere was previously demonstrated not to bind CENP-B (Voullaire et al., 1993). The abode results, therefore, established the localization of CENP-C, and probably CENP-A, on the marker centromere.

EXAMPLE 11 Localization of the anti-centromere antibody-binding domain For further walking into the marker centromere region, cosmid libraries were prepared from total yeast genomic DNA containing YACs-2, -3, -4, -6, -7, -13, and -17. Cosmid clones containing human DNA inserts were isolated by hybridization with human COT- 1 DNA using low stringency. All resulting cosmids were screened by standard FISH to confirm their localization to the expected marker centromere and normal chromosome 10 regions, and to eliminate clones that might have originated from other genomic sites due to chimeric YACs. Positive clones were then analyzed further with the ANTI-CEN/FISH methods, using CREST#6 to label the centromere. Fig. 3a (I and II) show examples of cosmid signals that mapped to the q'- and p'- side, respectively, of the marker centromere in the ANTI-CEN/FISH experiments. The cosmid tag (clone 10pC38) was used in these experiments to define the q' arm of the marker chromosome. For cosmid walking, we concentrated on clones derived from YAC-3 since FISH mapping of YAC contig #082 indicated that the marker centromere region was likely to be within this YAC. Fig. 4a shows a restriction map of the region covered by this and surrounding YACs and compares this map with a genomic map derived from patient BE. The relative positions of a series of cosmid clones (including five independent PACs) were also determined and placed on the YAC map. Fig. 4b presents the ANTI-CEN/FISH results obtained with a number of the cosmid clones and one of the PAC clones. Clones Y3C64, Y6C8, and Y3C94 localized preferentially to the q'-side, while Y13Cl+C8 and Y17C6 localized preferentially to the p'-side of the marker centromere, suggesting that the nucleus of the antibody-binding domain is situated between these two cosmid clusters. Within this central region, a group of cosmid clones comprising the HC-contig (Fig. 4a) was found to map closely around the ANTI-CEN signal. Fig.

4c shows a restriction map for eight different overlapping clones from this HC-contig. The chromosomal positions of five of these overlapping clones were analyzed in detail using ANTI- CEN/FISH. Fig. 4b shows the cumulative results for more than 60 informative chromosomes for each of these five probes. The results indicated that Y7C14 mapped preferentially q'- of the antibody-binding domain, while the remaining four clones (Y4C45, Y6C10, Y6C21 and Y3C3) mapped preferentially to the p'-side. In addition, the results for PACS (a 75 kb-insert PAC clone that overlapped with the p'-end of PAC4 by approximately 5 kb; see Fig. 4a) provided further

evidence for the emergence of the HC-contig region onto the p'-arm. Based on these results, we conclude that the eight contiguous cosmid clones within the HC-contig shown in Fig. 4c, which together constitute 80 kbp of DNA, have defined the nucleus of the antibody-binding domain of the marker centromere.

From the above ANTI-CEN/FISH results, it was difficult to determine if the sequences of the HC-contig and its surrounding DNA, both originally derived from a normal individual, were part of the marker centromere DNA, or whether these sequences simply flanked a transposed centromere DNA with an unrelated nucleotide composition. However, supporting evidence from the ANTI-CEN/FISH experiments suggested that the DNA of the HC-contig region appeared to be a part of the marker centromere. This came from the mapping of Y6C 10 and Y6C2 1 onto superstretched chromosomes that were occasionally detected in the slide preparations. An example of such mapping is shown in Fig. 3b using Y6C21. As can be seen, whilst a significant portion of Y6C21 hybridized to the p'-side of the CREST signal on the highly extended chromosome, a substantial portion of the cosmid DNA also overlapped directly with the CREST signal. This suggests that at least part of the HC-contig region actually comprises the same DNA sequence as the marker centromere. This possibility was further investigated by detailed genomic mapping.

EXAMPLE 12 The Marker Centromere DNA has a Similar or Identical Sequence Organization as the HC-Contig The genomic organization of the HC-contig region was compared with that of the corresponding DNA region of the mardel (10) chromosome. Three overlapping cosmids (Y7C14, Y6C10, and Y4C7, the latter being essentially the same as Y6C21; Fig. 4C) from the HC-contig were used as probes to analyze the restriction patterns of genomic DNA prepared from patient BE and those of his karyotypically normal parents. Fig. 5 shows examples of the band patterns obtained with Y6C10, while Table 1 summarizes the results for all the enzymes tested with Y7C14, Y6C10 and Y4C7. The detection of a single band on PFGE gels with a number of the enzymes indicated that the cosmid DNA sequences were unique within the

human genome (SfiI, SalI, KspI, KpnI and Bcn in Fig. 5A; Table 1). The detection of a single on PFGE gels with a number of the enzymes (ClaI in Fig. 5A; Table 1) could be explained by differential methylation of different restriction sites found in this region (Nelson and McClelland, 1991); the reproducibility of these multiple band patterns ruled out incomplete digestion as a possible cause. The multiple bands detected with the more frequent cutting enzymes on a standard gel (Fig. 5B and Table 1) were a result of the presence of cleavage sites present within the probe DNA, since similarly digested cosmid DNA electrophoresed next to the genomic DNA yielded identical patterns for all the bands not containing cosmid vector sequences. In all, 37 enzymes were used to generate more than 160 different fragments for the three cosmid probes (Table 1). The results indicated that, except for a polymorphic fragment found in one of the parents, an identical banding pattern was present in the genomic DNA of patient BE and those of his parents. Furthermore, when the restriction patterns obtained for the genomic DNA of patient BE were compared with those of the smatic hybrid cell line BE2C 1- 18-5F, which contained the marker chromosome but not the normal chromosome 10, no detectable difference was seen between the two DNA preparations within the HC-contig region (Fig. 5C).

In addition to Y7C14, Y6C10 and Y4C7, a host of other probes from within or surrounding the HC-contig have been tested, each with an average of 12 different informative enzymes. These probes included PAC4 (which spanned the entire HC-contig region shown in Fig. 4C), Y3C64, Y3C109, Y6C6, Y6C8, Y3C94, PAC1, Y3C90, Y4C4, Y4C8, Y4C13, and Y3C33. The results again indicated identical restriction enzyme patterns between patient BE and normal DNA.

Thus, through the analysis of a relatively large number of probes covering about 500 kb of YAC-3 around the HC-contig region, and the use of a high density of restriction enzymes that generated a range of fragments from <1 kb to ~ 1 Mb, it was evident that the marker centromere DNA and a substantial stretch of its adjoining regions showed no detectable difference against the corresponding genomic region of the normal chromosome 10.

Since a potential limitation of the above Southern blot analyses was that highly repeated sequences were not detected because of the preannealing step used in the hybridisation procedure, a different approach was employed to compare the DNA of the marker chromosome

and that of the normal chromosome 10. In this approach, oligonucleotide primers from different regions of the HC-contig were used to prepare a series of PCR fragments from the BE2C 1 - 18- 5F and BE2C1-18-lF hybrid cell lines. Electrophoretic comparison of such fragments, which randomly covered approximately 40 kb of the HC-contig, indicated no detectable difference between the two chromosomes and provided independent support for the results obtained in the Southern blot analyses. Thus, it can be concluded that the sequence organization of the marker centromere region is similar, if not identical, to that found in the HC-contig region of the normal chromosome 10.

EXAMPLE 13 Implications for Centromere Study and Mammalian Artificial Chromosome Construction The mammalian centromere has been difficult to study due to the massive amount of repetitive DNA normally associated with it. By avoiding such repetitive DNA and analyzing the unusual centromere found in the present marker chromosome, the inventors have created a much more tractable system for centromere studies. The present analysis has already shed some light on the important question of DNA sequence versus conformational requirement of a centromere, and on the intriguing concepts of latent centromeres and epigenetic mechanisms. One urgent application of this DNA is to use it to identify the primary protein(s) which binds to the centromeric DNA. Another important application of the marker centromere DNA is in the construction of mammalian artificial chromosomes. Such artificial chromosomes offer a potentially powerful vehicle for the structural and functional analysis of chromosomes, for the genetic manipulation of plants and animals, and for the stable transmission of therapeutic genes in human gene therapy. The artificial chromosomes require a functional mammalian centromere, and the marker centromere DNA element of the present invention now provides a suitable centromere especially because of its relatively small size in the absence of a-satellite DNA and its cloning stability, as indicated by the cosmid, YAK and BAC clones of the HC-contig and NC- contig.

EXAMPLE 14 Sequence analysis Figures 6, 16A and 16B show partial nucleotide sequences for the HC-contig (SEQ ID NO: 3) NC-contig [SEQ ID NO: 4] and F2 (BAC/F2-14) [SEQ ID NO: 5-29] regions, respectively.

EXAMPLE 15 Human Artificial Chromosome (HAC) The following are examples of the different approaches being used in the inventors' laboratory for the production of a HAC: Retrofitting of HC-contig DNA from normal chromosome 10 This procedure aims to produce HACs of 100 kb to >1Mb using the region of the normal chromosome 10 containing and surrounding the HC-contig DNA. The generation of a HAC by this approach will provide crucial proof that this normal DNA region can be reactivated to form a functional centromere.

A retrofitting procedure suitable for introducing human telomeres to both ends of any YAC prepared in the pYAC4 vector in the yeast host strain AB1380 has been previously described (Larin et al., 1994; Taylor et al., 1994, 1996). YACs (in particular YAC-3 and YAC-5) spanning the normal HC-contig region are used for retrofitting by plasmid constructs designed to recombine with their pYAC4 vector arms (Figure 7). The construct pLGTEL 1 is used to target the left arms of the YACs. This serves to add a LYS2 yeast selectable marker, gpt element for ultimate selection in mammalian and avian cell culture, and a human telomere. The right arm of the YACs are targeted by homologous recombination with pRANT 11 to produce a final construct where addif onal markers are introduced along with a second human telomere to cap the construct. Specifically, an ADE2 yeast marker is added and the URA3 gene of the YAC is disrupted, serving a useful role in negative selection of the construct. A neomycin (neo) resistance gene shown to function in mammalian and avian cells is also introduced. The finished

constructs are transfected into different cultured cell lines, including HT1080 (of human sarcoma origin) (Larin et al., 1994; Rasheed et al., 1974), DT40 (a recombination-proficient chicken cell line) (Dieken et al., 1996), and BE2CI-18-5f (a human/hamster somatic hybrid cell line containing the mardel (10) chromosome but not the normal chromosome 10).

In vitro cloning of HC-region into YAC/HAC vectors The different vectors used for the cloning of the normal and mardel (10) centromeric DNA in the preparation of HACs are summarised in Table 2.

A number of different YAC cloning strategies are employed: Conventional YAC cloning approach. Figures 8A-D show the different vectors used for cloning DNA as YACs by the conventional restriction/ligation methods. These YACs can then be shuttled into mammalian cells and tested for HAC function.

ALU-ALU circular TAR cloning approach. Transformation-associated recombination (TAR) in the yeast S. cerevisiae, is a method for constructing linear and circular YACs from mammalian DNA (Larionov et al., 1996a, 1996b). The recombination process is shown in Figure 9. Briefly, the technique involves the use of a vector (pVC39-AAH2, Fig. 8E) lacking an autonomous replicating sequence (ARS) but containing a functional yeast centromere (e.g. CEN6) and selectable marker (e.g. HIS 3), and two ALU DNA hooks to trap mammalian DNA by recombination at ALU sequences after co-transformation of linearized vector and high molecular weight DNA into yeast spheroplasts and followed by selection on medium lacking histidine. The key to the process is that the mammalian DNA provides an ARS (1 l-bp sequence found frequently in mammalian DNA) which allows the HIS+/CEN vector to replicate as a circular YAC. These YACs are very stable and range in size from 100 kb to greater than 600 kb (Larionov et al., 1996b).

pVC39-AAH2 vector is used to clone DNA from hybrid BE2CI-18-5f to make YACs with an average insert of 250 kb. This TAR vector is further modified to create pAAH-TCNa (Fig. 8G)

so that it has the ability to shuttle between yeast and mammalian cells (as outlined in Figure 10), including the potential to expose human telomeres (TEL) at each end of a cloned fragment using a unique restriction site I-SceI.

Semi-specific and specific circular TAR. A modified circular TAR method utilising two specific 5'C and 3'C DNA hooks (300-700 bp in size) may be used to clone a specific human DNA at a frequency of 3/1000 HIS+ transformants. The inventors prepared the vectors pVC39- ALU/C3-F2(+/-) and pTCN-TCS (Table 2) to perform semi-specific and specific TAR cloning, respectively.

The Semi-specific TAR methodology is a modification of a specific circular TAR strategy which permits the site directed isolation of target chromosomal DNA. Furthermore, in accordance with the present invention, the methodology described herein enables the site-specific cloning of target chromosomal DNA from total genomic DNA as a circular YAC at relatively high frequencies and without the need for the construction and extensive screening of complex libraries made from genomic DNA.

In a preferred embodiment of the present invention, the methodology employs a single specific DNA hook which flanks the mardel (10) chromosome and a less specific Alu-hook to trap the other side of the target DNA.

In initial experiments, a unique repeat DNA-free, 1.4kb EcoRI fragment (designated C3-F2) was identified from the p' side of the 80-kb HC-contig (Fig. 11A) (du Sart et al., 1997). This fragment was subcloned into the centromere-based yeast circular TAR vector, pVC39-AAH2, by replacing the existing BLUR13 Alu (Larionov et al., 1996b) to create the pVC39-ALU/C3-F2 constructs. As the specific orientation of the C3-F2 sequence on the chromosome was not known, the fragment was cloned in two different orientations, for which the (+) orientation (Fig.

1 lB) was expected to trap the genomic region to the left of C3-F2, while the (-) orientation was expected to trap the region to the right. Both constructs were used in yeast transformation.

As a source of genomic DNA containing the neo-centromere, a somatic hybrid cell line, BE2C 1-

18-5f (du Sart et al., 1997), containing the mardel 10 chromosome but not the norrnal human chromosome 10 was used. 5pg of high-molecular-weight DNA from this cell line and lpg of pVC39-ALU/C3-F2(+) or pVC39-Alu/C3-F2(-) (linearized with SmaI to expose the 0.21 -kb Alu and 1.4-kb C3-F2 hooks) were co-transformed into 109 (previously prepared and stored frozen) spheroplasts of S. cerevisiae YPH857 which carries a HIS3 gene deletion, (Sikorski and Hieter, 1989) and grown on SD, without HIS medium, (Larionov et al., 1996a;b) to yield between 10 and 100 HIS+ colonies. Control experiments in which YPH857 was transformed with vector alone did not produce any colonies, indicating that the C3-F2 fragment lacked ARS-like sequences. Twenty TAR experiments were performed and HIS+ colonies were picked into 96- well trays containing YPD medium (supplemented with 50pg/ml ampicillin and 1 Spg/ml tetracycline), grown at 300C with aeration for 24h and stored in 20% (v/v) glycerol at -70°C.

Total yeast DNA was prepared in pools of 48 (Kwiatkowski jr et al., 1990) and screened by PCR with the primers norm 5 and norm 7 (Table 3) which are located 30-kb q' of C3-F2 (Fig.

1 lA). Two desired positive clones, designated 5f-52-E8 and 5f-38-F2, which contained the neo- centromere DNA derived from mardel 10 and mardel (10) and the DNA immediately p' of the neocentromeric DNA, respectively, were identified. For subsequent studies, these clones were grown on SD without HIS medium and single colonies were re-isolated for characterization.

Initially, the sequence nature and sizes of the 5f-52-E8 and 5f-38-F2 insert DNA were determined. Highmolecular-weight DNA was prepared in agarose blocks and digested with an enzyme (sol) that linearized with YAC (Fig. 1 lA). The linearized DNA, as well as uncut intact DNA, were resolved by pulsed-field gel electrophoresis (PFGE), transferred onto a nylon membrane and probed with radiolabelled PAC4, a P1-derived artificial chromosome clone containing a 120-kb insert that spans the entire HC-contig from normal chromosome 10, (du Sart et al., 1997) following preannealing with human placental DNA to suppress repetitive DNA.

The intact 5f-52-E8 and 5f-38-F2 remained trapped in the electrophoretic wells and the linearized DNA migrated into the gel and demonstrated a size of approximately 110 kbp and 80 kbp, suggesting insert sizes of about 105 kbp and 75 kbp, respectively (given that the vector size is 5.9 kb).

Despite the use of a genomic DNA source previously shown by sequence-tag-site (STS) analysis

to be free from normal chromosome 10 material, it is desirable to independently confirm the mardel (10) -origin of the 5f-52-E8 YAC clone. This was achieved using a set of primers (norm 17 and 18; Fig. 1 it) that detected a variable-number-tandem repeat (VNTR) region within the HC-contig/neocentromere region. The results clearly indicated the presence of a 1.4-kb PCR product that was specific for the mardel (10) chromosome (Table 3).

PCR was used to further compare the 5f-52-E8 DNA with the previously cloned HC-contig sequence derived from normal chromosome 10. PCR products with sizes ranging between 0.2 and 15.9 kb were generated by standard PCR or with the Expand Long Template PCR system (Boehringer-Manneheim). Products greater than 1 kb were digested with frequent cutting enzymes, RsaI and BsiXI, and their fingerprints were compared by agarose gel electrophoresis.

The results, shown in Table 3, indicated the absence of any detectable difference between the Sf- 52-E8 DNA and those of the corresponding regions of the normal chromosome 10 (in somatic cell hybrid BE2C1-18-lf) and the neocentromere region of mardel (10) (in somatic cell hybrid BE2C1-18-5f). These results also demonstrated that the YAC 5f-52-E8 spanned at least 75 kb of the HC-contig region (Fig. 1 lC), consistent with the size determined by PFGE. Furthermore, the ability of all the internal primers to amplify DNA from 5f-52-E8 strongly suggested that the YAC was not chimeric. This result was confirmed by isolating DNA from four single-colony isolates of 5f-52-E8, digesting these with EcoRI and EcoRV, and probing with radiolabelled PAC4. The hybridization patterns obtained with these enzymes were consistent with those established in the previous study (du Sart et al., 1997). Thus, this analysis, based on cloned DNA derived directly from mardel 10, has provided confirmation that the neocentromere DNA region is structurally identical to that of the corresponding HC-contig region of the normal chromosome 10 (du Sart et al., 1997).

The circular YACs 5f-52-E8 and 5f-38-F2 were further retrofitted with the yeast-bacterial- mammalian cells shuttle vector BRV1 as previously described (Larionov et al., 1997). The resulting BAC clones were designated BAC/E8-1 and BAC/F2-14, respectively (Fig. 1 1D).

The specific TAR strategy is outlined in Figure 12 and uses unique fragments from the HC- contig region, such as the ends of PAC4 (a 120 kb-insert PAC clone containing the HC-region)

to create the YAC/HAC shuttle vector pTCN-TCS. An example of a YAC/HAC construct containing the HC-contig region of normal chromosome 10 is shown in Fig 13.

Completed constructs are transfected into different cultured mammalian or chicken cells (see above) by lipofection using Transfectam or DOSPER.

In vivo "cloning" of HC-region into HAC vectors This strategy employs a technique known as Telomere Associated Chromosomal Truncation (TACT) (Fig. 14). The technique is based on the principle that cloned mammalian telomeric DNA when reintroduced into a mammalian cell can seed the formation of a new telomere at an intrachromosomal location. If the introduced telomeric DNA is targeted to a known site through homologous recombination, integration at that location and subsequent truncation of distal sequences on the original chromomosomal arm can result (Brown et al., 1994; Farr et al., 1995).

This technique is employed in our own study to truncate the mardel 10 chromosome on either side of the HC-contig/core centromeric DNA element to produce in vivo a stable HAC of minimal size.

Figure l5A shows an example of TACT-construct used in our study. Key features of this construct are: (a) Cloning of the pericentric human genomic DNA in both orientations (+1-). This is necessary since we do not know the chromosomal orientation of this DNA. This DNA is used to target the human telomeric sequences to locations on either side of the HC-contig region on mardel 10. Genomic DNA is derived from several different sources including Y2C24, Y3C64, Y3C109, Y3C94, Y13C12, Y13C15, Y17C6, Y17C8. The resulting truncation derivatives produced using these genomic DNAs will vary in size accordingly. (b) The termini contain 2.4 kilobases of tandem repeat human telomeric DNA (htel). This DNA has been shown previously to act as a substrate for mammalian telomerase to allow seeding of a complete telomere tens of kilobases in length. (c) The hygromycin (Hyg) resistance gene allows for positive selection of mammalian cell lines containing construct sequences integrated into the genome. This is the initial screening procedure. In addition, some constructs contain the neomycin phosophotransferase gene (Neo) rather than Hyg. (c) The Herpes simplex thymidine kinase (TK)

gene is used for negative selection against non homologous integration events into the genome.

Those cell lines containing the TK gene can be selected against by adding the nucleoside analogue gancyclovir.

Figure 1 SB shows another example of TACT-construct used in our study. In addition to the features of the linearised construct shown in Fig. l5A, specific additional features are: (a) The incorporation of tandem telomeric blocks (htel.htel) since others have shown these to have the highest seeding efficiency of new telomeres in mammalian cells. (b) The incorporation of yeast selectable marker (eg. URA3), DNA origin of replication (eg. ARS), and centromere (eg.

CEN6), to allow transfer and maintenance of the resulting truncation derivatives into yeast. This should facilitate further characterisation and manipulation, such as the introduction of therapeutic genes for gene therapy purposes. (c) The relocation of the TK gene adjacent to the genomic DNA to increase the effectiveness of the negative selection system. (d) The human growth hormone (GH) gene has been included to allow proof of principle that human genes can be introduced into a HAC and expressed under the control of endogenous regulatory elements. This is essential for gene therapy applications of the resulting HAC. (e) A CMV promoter upstream of a P1 phage loxP site (CMV/loxP) has been included to allow introduction of large human genes into a HAC in vivo. A plasmid containing a gene of interest, a second loxP site and a promoterless selectable marker gene is introduced into a mammalian cell line containing the HAC. Transient expression of CRE recombinase results in recombination between the two loxP sites within the cell, thereby integrating the introduced plasmid into the HAC and placing the selectable marker gene next to the CMV promoter to allow for marker selection.

For chromosomal truncation, the above TACT-constructs are transfected into a somatic cell hybrid line BE2CI-18-5f containing the mardel (10) chromosome. Positive selection is applied for Hygromycin or Geneticin resistance whereas negative selection is applied against the Thymidine Kinase Gene. Resulting colonies are further screened with distal p' and q' DNA fragments to ascertain the presence or absence of the two mardel 10 chromosome arms. In addition to the BE2CI-18-5fcell line, a human/chicken somatic cell hybrid line (derived from the recombination-proflcient DT40 chicken cell line; Dieken et al., 1996) containing the mardel (10) chromosome will also be generated and used.

EXAMPLE 16 Analysis of HAC Irrespective of which of the approaches described above is used, the presence of a new product in a mammalian cell line as an extrachromosomal, artificial chromosome, will be assessed by fluorescence in situ hybridisation (FISH) analysis, as well as tested by extracting high molecular weight DNA to determine independently existing chromosomal entity on pulsed field gel. The stability of the construct through successive cell division, both in the presence and absence of drug-resistance selection, will be determined. The presence of the construct, in all or a high percentage of the original transfected cells indicates stability. Demonstration of this stability indicates the successful creation of a HAC.

EXAMPLE 17 Production of HAC This example describes the use of the neocentromere as a source of centromeric DNA in the "bottom-up" approach to produce HACs in human cell culture. Bacterial artificial chromosomes (BACs) containing cloned neocentromeric DNA and a selectable marker were co-transfected with human telomeric DNA into human HT1080 cells to yield independent HACs that were single-copy and stable in the absence of selection. The properties of these HACs, and their potential utility as a new, improved vector system for gene therapy are described.

EXPERIMENTAL PROTOCOL Preparation of DNA. Higlily-purifled BAC DNA was prepared using Qiagen columns according to the manufacturer's instructions. Prior to transfection, BACs were linearized with SgrAI in the presence of 2.5 mM spermidine and examined by pulsed-field gel electrophoresis. Human telomeric DNA was gel-purified as a 1.6-kb BamHIIBglII fragment from pSXneo270T2AG3 (Bianchi et al., 1997). High-molecular-weight genomic DNA was prepared from cultured cell lines using standard methods (du Sart et al., 1997).

Transfection of HT1080 cells Transfection of human fibrosarcoma cell line HT1080 (Rasheed et al., 1974) was performed using the DOPSER liposomal transfection reagent (Boehringer- Mannheim). The day before transfection, 6-well trays (each well is 962 mm2) were seeded with 3 x 105 HT1080 cells per well and grown at 37or, 5% CO2. Different combinations containing 1-2 Rg of each BAC, 50 ng of telomeric DNA, 100 ng of each PAC-1, 4 and 5 (du Sart et al., 1997) and 50 ng of human genomic DNA were prepared in 50 Fl of HBS (20 mM HEPES, 150 mM NaC1) supplemented with 0.075 mM spermidine and 0.030 mM spermine. These DNA cocktails were mixed with 50 ul of 0.4 Slg/Rl DOPSER (diluted in HBS) and left at room temperature for 15 to 20 mien. The HT1080 cells were washed with PBS (phosphate buffered saline) and 1 ml of serum-free DMEM (Dulbecco's modified Eagles medium) was placed in each well. The DNA-DOPSER mixture was then added dropwise with swirling and the cells were incubated for 6 h. 1 ml of DMEM and 20% v/v fetal calf serum (FCS) was then added and the cells left for 24 h at 37cC, 5% v/v CO2 .The cells were harvested and seeded into 48-well cluster trays (each well is 100 mm2) containing DMEM-10% v/v FCS supplemented with Geneticin (G418, Gibco-BRL) at 250 Rg/ml. The media was changed every 3 to 4 days. G418-resistant colonies normally appeared 10 to 14 days after transfection. These colonies were expanded into duplicate 6-well trays, where the cells of one tray were stored frozen in liquid N2, and the remaining cells were analysed by fluorescence in situ hybridization (FISH).

Cell culture and mitotic stability. HT1080 cells were grown in DMEM supplemented with 10% v/v FCS, penicillin/streptomycin, and glutamine. The mitotic stability of HAC containing clones was determined by growth in 25 cm2 flasks in the presence (200-250 Rg/ml) or absence of G418 selection, and grown to confluency (3-4 days) and split 1/5 and 1/10, respectively.

Aliquots of each culture were harvested fortnightly and analysed by FISH (20-50 metaphases) with BAC/E8 and/or BAC/F2 probes.

FISH, ANTI-CEN/FISH and PRINS/FISH. Fluorescence in situ hybridization (FISH) analysis of Hut 1080 clones was performed with BAC/E8, BAC/F2, and/or a-satellite DNA probes.

Hybridization using the BAC probes were performed under high stringency whereas the a- satellite DNA probes were used in low stringency conditions (du Sart et al., 1997). ANTI-

CEN/FISH analyses involved an initial immunofluorescence staining step using a CREST antibody or specific antibodies against CENP-B, CENP-C, or CENP-E, followed by FISH using the probes described above, essentially as previously described (du Sart et al., 1997).

Results HAC construction strategy. The basic strategy involved the co-transfection of the 10q25.2 neocentromere DNA with human telomeric DNA into human cells. The neocentromere region is cloned as two, circular YACs in Saccharomyces cerevisiae. To facilitate handling and purification of the cloned DNA in large quantities, these YACs are retrofitted into BACs and maintained episomally in E. coli as circular molecules. One of the BAC clones, BAC/E8, is 120 kb in size and has an insert of 105 kb that encompassed 70 kb of the 80-kb core NC-DNA region (Fig. 16). The second BAC clone, BAC/F2, has an insert size of 75 kb that overlapped BAC/E8 by 1.4 kb, and contains 10 kb of the core NC-DNA while extending 65 kb into the p'-side of the mardel (10) chromosome (Fig. 16). The BAC vector backbone further contains the neomycin-resistance (NeoR) gene to allow selection in mammalian cells. BAC/E8 and BAC/F2, used either on their own, in combination with each other or with additional DNA are used in the following transfection experiments.

Transfection of HT1080 cells. The human cell line HT1080 (Rasheed et al., 1974) is chosen for the transfection experiments because of its near-diploid karyotype, its high level of telomerase activity (Holt et al., 1997), and its demonstrated ability to form microchromosomes containing de novo centromeres from transfected arrays of a-satellite DNA and human telomeric DNA (Harrington et al., 1997; Ikeno et al., 1998). The resulting G418-resistant clones are analyzed by FISH and classified into different categories of events.

Transfected cell lines are designated HT-38, HT-47, HT-54, HT-190, and HT-191.

Those skilled in the art will appreciate that the invention described herein is susceptible to variation and modifications other than those specifically described. It is to be understood that the invention includes all such variations and modifications. The invention also includes all of the steps, features, compositions and compounds referred to or indicated in this specification, individually or collectively, and any and all combinations of any two or more said steps or features.

TABLE 1 Restriction analysis of the genomic DNA of patient BE and those of his parents using three overlapping cosmids that span the marker centromere.

Y7C14 Y6C10 Y4C7 NotI n.a. 910 910 BssHII n.a. 815, 340 n.a.

BsiWI n.a. 740 740 SalI 410 410 410,540 ClaI 315, 145, 110, 80 315, 145, 110, 80 315, 145, 110, 80 SnaBI n.a. 250, 148 n.a.

NaeI 240, 210, 155, 120 240, 210, 155, 120 240, 210, 155, 120 NarI 222, 108, 70 222, 108 222, 200, 108, 70 EclXI 180 180 180 SfiI 170 170 170 KspI 168 168 168 Aatll 165, 146 165, 146 165, 146 NheI 38 38 38 BstBI n.a. 35 35 SmaI n.a. 90, 40, 22 90, 40, 22 BglI 25 25, 7.2, 6.2 25 PacI n.a. 25 n.a.

BamHI 24, 19, 15 24, 22* 24, 22* KpnI 23 23 23, 19 BclI 21 21 21 PstI 9.4, 5.9, 5.1, 4.2, 3.8, 9.4, 3.8, 2.9, 2.7, 2.4, 9.4, 7.1, 4.2, 3.3, 2.9, 3.3,2.9,2.4 1.5, 1.1 2.7, 1.9, 1.5, 1.1 XbaI 14 14, 10 10 EaeI n.a. 15, 12, 8, 6 n.a.

SphI 16,7.5 16 16,9 Pvull 14, 7.5 7.5, 6 7.5, 6 HindII 8.6, 6.9, 6.2, 2.7, 1.8, 6.9, 6.2, 5.6, 5.2, 5, 2.7, 6.2, 5.6, 5.2, 4.3, 2.9, 1.2 1.9, 1.8, 1.7, 1.2, 0.6 1.7, 1.2 Papal 15, 8.5 15 15 11,4.3,3.9,1.9,1.5 11,4,3,2, 1.9, 1.7, 1.5 10.2,7.6,3,2,1.9,1.7, EcoRI 1.5 Hpall 5.5, 4.3, 3.6, 1.6 6.9, 3.6, 2.8, 1.6, 1.2 3.6, 2.8, 2.5, 1.6, 1.2 MspI 3.9, 3.0, 2.8, 2.5, 2, 1.6, 3.9, 3.6, 2.8, 2.5, 2.2, 3.6, 3.2, 2.8, 2.5, 2.2, 1.2 1.6, 1.5, 1.3, 1.2,0.9 1.6, 1.5, 1.2, 1 SspI n.a. 10 n.a.

XhoII 7.5 n.a. n.a.

DraI 7.5 7.5 7.5 BglII 8.5, 6, 5, 4.7, 3.5, 2.5 6, 5, 4.7, 2.5, 1.6, 1.5, 1 7, 6, 5, 4.7, 2.5, 1.6, 1.5, 1.1, 1 AvaII 7.4, 3.7, 3.4, 2.8, 2.6, 3.7, 2.8, 2.6, 1.8, 1.7, 4.3, 3.7, 2.8, 2.6, 1.8, 1.8, 1.7, 1.4, 1.2,1.1 1.4,1.2,1.1,0.9,0.8, 1.7, 1.4, 1.2 0.5 StuI 12.5, 8, 7.5 12.5, 9, 8.5 9, 8.5 HindIII 6.6,5.4,4.7,4.4,2.9, 5,4.7,4.4,4.1,2.9,2.5, 5,4.7,4.1,3.1,2.5,2.3, 2.5 0.7 1.9 n.a.= data not available.The values represent restriction fragment lengths in kilobases. Multiple values for an enzyme denote different bands detected by a cosmid probe on a gel lane. Since there were no detectable differences between the DNA of patient BE and those of his parents in any of the fragments (except for a BamHI polymorphic band found in one of the parents, indicated by an asterisk), only one set of values is shown for all three genomic DNA.

TABLE 2 Table 2. Vectors for cloning centromeric regions from normal chromosome 10 or mardel (10) DNA into yeast artificial chromosomes (YACs). These YACs can be shuttled into mammalian cells to test for function as HACs.

Vector: Key Feature(s) Map pJS97ARTi hTEL/I-SceI/yTEL, DHFR Fig.8A pJS98ANTi hTEL/I-SceI/yTEL, neo Fig.8B Fragmentation 1 hTEL/I-SceI/yTEL, hyg Fig.8C Fragmentation 2 (-/+ hGH) hTEL/I-SceI/yTEL, neo, hGH Fig.8D pVC39-AAH2 ALU-ALU TAR vector Fig.8E pTEL/CAT/TEL hTEL/I-SceI/hTEL/neo Fig.8F pAAH/TCNa TAR vector with hTEL/I-SceI/hTEL/neo Fig.8G pVC39-ALU/C3-F2(+/-) ALU-specifc TAR vectors Fig.8H pTCS ends of PAC4 in pBS Fig.8I pTCN-TCS specific TAR vector hTEL/I-SceI/hTEL/neo Fig.8J TABLE 3 PCR analysis of YAC 5f-52-ES clone and comparison with the HC-contig/neo- centromere region from normal chromosome 10 and mar del (10) Primer-Pairs a Genomic DNA used in PCR (product size in kb) BE2C 1-18-1fb BE2C 1-18-5fb YAC 5f-52-E8 norm: 141 + 55 1.80 1.80 not present norm: 32 + 30 0.90 0.90 0.90 norm: 28 + 29 1.00 1.00 1.00 norm: 1 + 3 2.90 2.90 2.90 norm: 39+52 1.20 1.20 1.20 norm: 5 + 7 0.23 0.23 0.23 norm: 16+5 3 50 3.50 3 50 norm 9+ 14 0 90 0.90 0.90 norm: 36 + 37 2.00 2.00 2.00 norm: 168 + 71 4.00 4.00 4.00 norm: 27+10 15.90 15.90 15.90 norm: 18 + 17 (VNTR)C 1.20 1.40 1.40 norm: 68 + 17 8.00 8.00 8.00 norm: 34 + 47 3.00 3.00 3.00 PAC4t7: a + b 0.30 0.30 not present AFM259xg5:ca + gtc 0.21 0.19 not present Refer to Fig. 1 a for the relative positions of each primer-pair.

b BE2C1-18-1f and BE2Cl-18-5fare somatic hybrid cell lines containing the normal human chromosome 10 and mar del (10), respectively (2).

CThe 'norm: 18 + 17' and 'AFM259xg5: ca and gt' primer sets allow distinction between the normal human chromosome 10 and mar del (10) by detecting a VNTR and a microsatellite, respectively.

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SEQUENCE LISTING (1) GENERAL INFORMATION: (i) APPLICANT: (US ONLY) CHOO, Kong-Hong Andy, DU SART, Desiree and CANCILLA, Michael Robert (OTHER THAN US) AMRAD OPERATIONS PTY LTD (ii) TITLE OF INVENTION: A NOVEL NUCLEIC ACID MOLECULE (iii) NUMBER OF SEQUENCES: 29 (iv) CORRESPONDENCE ADDRESS: (A) ADDRESSEE: DAVIES COLLISON CAVE (B) STREET: 1 LITTLE COLLINS STREET (C) CITY: MELBOURNE (D) STATE: VICTORIA (E) COUNTRY: AUSTRALIA (F) ZIP: 3000 (v) COMPUTER READABLE FORM: (A) MEDIUM TYPE: Floppy disk (B) COMPUTER: IBM PC compatible (C) OPERATING SYSTEM: PC-DOS/MS-DOS (D) SOFTWARE: PatentIn Release #1.0, Version #1.25 (vi) CURRENT APPLICATION DATA: (A) APPLICATION NUMBER: (B) FILING DATE: 13-MAY-1998 (vii) PRIOR APPLICATION DATA: (A) APPLICATION NUMBER: PO6784 (B) FILING DATE: 13-MAY-1998 (vii) PRIOR APPLICATION DATA: (A) APPLICATION NUMBER: PO8791 (B) FILING DATE: 26-AUG-1997 (viii) ATTORNEY/AGENT INFORMATION: (A) NAME: HUGHES DR, E JOHN L (C) REFERENCE/DOCKET NUMBER: EJH/AF (ix) TELECOMMUNICATION INFORMATION: (A) TELEPHONE: +61 3 9254 2777 (B) TELEFAX: +61 3 9254 2770 (2) INFORMATION FOR SEQ ID NO:1: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 19 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:1: GGATTACAGG (C/T)(A/G)TGAGCCA 19 (2) INFORMATION FOR SEQ ID NO:2: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 19 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:2: (A/G)CCA(C/T)TGCAC TGCAGCCTG 19 (2) INFORMATION FOR SEQ ID NO:3a: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 40917 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:3a: GAATTCTCCT GCCTCAGCCT CCCAAGTAGC TGAGGTTACA GGTGCCAGCC ACCACGTCCA 60 GCTAATTTTT GTATTTTAGT AGAGACGGGG TTTCACCGTG TTTGCCAGGC TGGTATCAAA 120 CTCCTGACCT CAAGTGATCT GCCTGCCTCA GCCTCCCAAA ATGCTAGGAT TACAGGTGTG 180 AGTCACCGCA CCCAGCCCTT CTTTCAGTTC TATCACCTCT TTTTGCTATA TTTGTATGAG 240 AGCTTTATTA TTAGGGGCAC ATACATTTAA AATTGTTATG TCTTATTGAT AGATTGATCT 300 GTCATTATGA ATGTCTGTAT TCATTCCCTG ATAGTATTTC TTTTTCTAAA TATTTTTCTG 360 AATGTGTCTG CTATTAACAT AGCCACTCTG GCTTTTTAAA ATTAGTATTT TTATGGTATA 420 TATTTTTCCT TTTTTTTTTT TTTAAGTTTT AGATGTTATG TTTCCTTATA CTTAAAGTGG 480 GTGTCTTATA GGCAGCATAT ATCTGGGTCT TGATGTATTA TTTAATCTGA TAATCTCAAC 540 CTTTTTGTTG GAGTGTTTAG GCCATTTACA TTTAGTGTAA TTATAGACAT GGTTTGATTT 600 GCTATACCAT CTTTTCATTT GTTTTATATG TGAGCCATCT TTTCATTGTT CTTTTTTCAT 660 CTTTGACCAT TTTCTTTAGT ACTGAATACT TTTTTTGTAT TTCATTATAT CTATTGGCTT 720 TTTAGTTATA CCTCTTAAAA TTTTTTTTTC TGTTTTATGT AGGATTTATA ATATACATCT 780 TTAACTTATC ACAGATTACC TTCAAATAGT ATTTTAC CAG C TCAAGTGTA ATGTAGAAAC 840 CTTACAAGAG TATATTTTCA TTTCTGTCTC CTAATTTTTA TGCTATGTCT ATAATACATT 900 AGGTTTGTTG TTGTTTGTTT TTACCTTATT GCTGTTGGCT GGGGTCAGCA AACATTTTCT 960 GTAAAGGGCT AGATAGTACA GGCATACCTT GGAGATACTG TGGGTTTGGT TCCATACCAC 1020 CACAATAATA CAAATATGCA AGAAGTGGAT ATCACAATAA AGTGAGTCAC ACAAGTCTTT 1080 TGGCTTCCCA GTGCATATAA AAGTTTTGCT TATACTACAC TGTAGTCTGT TAAGTGTGCA 1140 ATAGTGTTAT GTCTAAAAAA ACACATACCT TAATTTTAAA ATGCTTTATT ACTAAAAAAT 1200 GCTAACAATC ATTTGAGCAT TCAGTGAGTT GTAATCTTTT TGCTGGTGGA AGGTCTTTTC 1260 TTATTGATGA CTGATCGGGG GTCAGGTGCT GAAGCTTAGG GTGGCTGTGG CAGTTTCTTA 1320 AAACAACAGT GAAGATTGCA ATATCAGTTG ACTCTTCCTT TCATGAAAGA TTTCTCTCTA 1380 GTGTGTGATG CTTTTTGATA GCATTTTATG CACAGTAGAA CTTCTTTGAA AATTGGATCA 1440 ATCCTCTCAA ACCCTGCTCT GCTTTAACAA CCTAAGTTAA TATAATATTC TGAATCCATT 1500 GTTGTCATTT CAACAATTTT CACAGTGTCT TCACCAGGAG TAGATTCCAT CTCATTTCCT 1560 GAGATGGAAT CTTTGCTCAT CCATAAGAAG AAATTCCTCA TCTGTTCAAG TTTTATCATG 1620 AGATTGCAGC AATACAGTCA TGTCTTCAGG CCTCACTTCA CTTTTAATTC CAGTTCTCTT 1680 GCTGTTTCTA CCACATCTGT GGTTCCTTCC TCCATTGAAG TCTTGAACCT CTCCAAGTCA 1740 TCCATGAGGG TTGGAATCGA CTTCTTCCAA ATTCCTGTTA ATATTTATAT TTTGACCTCC 1800 CATGAATCAT GAATGTTCTT AATGGCACCT GGAATGGTGA ATCCTTTCCA AAAGGTTTTC 1860 AATTTACTTA GTCCAGATCC ATCCATCCAG AGGATCCACT TTCAATGCCA GTTATAGCCT 1920 TATGGAATGT ATTTCTTCAA TAATAAGGCT TGAAAGTTGA AATTACTCCT TGATCCATTT 1980 TCTGCAAAAT AGATGTTGTG TTAGCAGGCA TGAAAGCAAC ATTAATCTTT TTGTACATGT 2040 CCATCAGAGC TCTTGGGTGA CCAGGTATAT TGCCAGTGAG CAGTAATACT TTGAAAGGAA 2100 TTATTTTTCT TAGCAGTAGG TCTCAACAAT GGGCTTAAAA TATTTGGTCC ACCATTCTGT 2160 AAACTGATGT GCTGTCATCT AAACTTTGTA GTTTCATTTA TAGAGCACAG GCAGAGTAGA 2220 TGTAGCATAA TTCTTAAGGG ACTTAGGATT TTCAGAATGG TAAATGAACA TTGGCATCAA 2280 TTTAAATCAC TAGCTGTATT AGCCCCCAAC AAGAGAGTCA GCCTATTTTT TGAAGCTTTG 2340 AAGCCAAGCG TCGACTTCTC CTCCCTGGTT ACAAAAGTCC TAAATGGCAT CTTCTTCCAA 2400 TATAAGGCTG TTTTATCTAC ATTGAAAATC TGTTGTTTAG TGTAGCCACC TTCATCAATG 2460 ATACTATCTA GATCTCTTGG ATAACTTGTG CAGCTTCTAC ATCAGCATTT GCTACTTCAC 2520 CTTGTACTCT TATGTAATGG AGTGGCATCT TTCCTCGTAC CTCATGAACC AACCTCTGCT 2580 AGCTTCCAAC TTTTCTTCTG TAGTTTCCTC GCCTCTCTCA GCCTTCATAG ACTTGAGGAT 2640 AGTTAGAGAC TTGCTTTGGA TTAGATTTTG GCTTCAGGAA ATGTTGTGGC TGGTTTGATC 2700 TTCTATCCAG ACCACTAAAA CTTTATCCAT ATCAGCAATA AGGCTGTTTT GCTTTCTTAT 2760 TATTTGTGTG TTCACTGGAG TAGCACTTTT AATTTGCTTC AAGATATATT TCTTTGCATT 2820 CACAACTTGG CTGACTGGTG CAAGAGGCCT AGCTTTCAGA CTATCTTGGC TTTTGACATG 2880 CCTTCCTCAC TAAGCTTAAT CATTTCTAGC TTTTGATTTA AAATGAGAGA TGTAGGCCAG 2940 GCACAGTGGC AGGCACAGTG GCATATGCCT GTAATTCCAA CACATTAAGA GGCCAAGGTG 3000 GGAGGATTGC TTGAACCCAG GAGGTGGAGG TTGTAGAGAT CACACCACTG CATTCCGTCC 3060 TGGATGACAG AGCAAGACCT TTCTCAAAAT AAAATGAGAG GTGTGCTTCT TCTTTTTGTT 3120 TGAGCCCATA GAAGCCATAG TATGATTTTT AATTGGCCTA ATTTCAATAC TGTTGTGTCT 3180 CAGAGAATAG GGAGGTCTGA AGAGAGGGAG AGAGGTGGGG GAATGGCTGG TCAGTGGAGC 3240 AGTCAGAACA CACATAACAC TAATAAATTG TTTGCTGTCT TATATGGATG TGGTTTGTGA 3300 TGCCCCCAAA CAATTACAAT AGTTACAGCA AATATCACTG ATCACAGATC ACCATAACAG 3360 ATATAAGAAT CATGGCAAAG TTTGAAATAT TCTTGAGAAT TAGCAAAGTG TGACACAGAG 3420 AAACAAAGTG AGCACATGCC GTTGGAAAAA ATTGGTGTTG ATAGACTTGC TCCATCGCAA 3480 GTTTGCCATA CGCCTTCAAT TTATAAAAAA CACAATATCT AGGAAGTTCA ATAAAGTGAA 3540 GTGCAATAAG ATGAAGTATG CCTGTAAATA TTTCAGGCTT TCCAGACCAT AGGGTTTCTG 3600 TTGCAACTGC TCACCTCTGC CATTATAGCA TGAAAGCAGC TATAGAAAAT ATACATAAAT 3660 GAGGCCTGTA ATCCCAACAC TTTGGGAGCC CAAGGTGGAT GGATCACTTG AGGTCAGGAA 3720 TTCGAGACCA GCTTGGCCAA CATGGCAAAA CCCCGTCTCT ACTAAAAATA CAAAAATGAG 3780 CCAGGACTAC GCATGCCTGT AGTCCCAGCT ACTTGGGAGG CTGAGGCAGG AGAATCTCTT 3840 GAACCCGGGA AGGGGAGGTT ACAGTGAGCC AAGATTGTGC CACTGCACTC CAGCCTGGGC 3900 AACAGAGTGA GACTGTCTCA CAAAAAAAAA AAAAGGAAAA GAAAATACAC ATAAATGAAT 3960 GTATGTGGCT GTGTACCAGT ATATCCTCAT GCTCTAGCTT GCCAACCCTT GCTTTACACT 4020 GTCAGTTACC TTCTAAAGAG ATTAAAAATC ATAACAATAT CTATTACGTT TATTCACATC 4080 CTAGTGTCAT TTCTTCCTTA TGTAGAATCA AATTTCATTC TGGTATCATA TTTCTTCTTT 4140 CTAAATAATT TCCTTTAATA TTTTTTATAG CACAGGTCTA ATAGCAATGC ATTATGCAAT 4200 TCATTGCTAT TAGACCTGTG CTATAAAATA GCAATGAATT ATGTCAGTTT TTATTTGTCT 4260 GAAAAAGTTT TTTGTTTTTG AAATATACTT TTGCTGGGTA TATAAATCCA TGTTGCATAA 4320 CTTCTCTTTT CTTCAGCACT TTAATGAAGT CACTCAGTTA TCTTCTGGCT TGTATAGTTT 4380 CTCTGGCTGC CTTCAAGATT TTTTCATTGT CTTTAATTTT TAGCAGTTTG ATGTGTCTAG 4440 GAGTGATTTT CTTTGTATTT ATCCTTTTGG GGGCCTCTTA ATTTCTTTGA TCCTTTTTTT 4500 CTTTTTTTTT TTTTTTTAAT CAGTTTTGGT CTGTCTCCTC AAGTGGGCTG AAAAAAAAAG 4560 AAAAATAAAA TCATAGTTTA AAAAACTAAT TTTGGAAAAT TTTCAGCTAT CATTTCTTCA 4620 AATATTTATC CTACTCTATG CTCCCCTCCT CCCCTTTCCT TCTGTGACTC AAATTACAGG 4680 TATATTTAAC CATTTTATTT GTTCACGGCA CTTGGATGCT CTGCTTTCTT ATTTTTTGTC 4740 TTTCATTTTG GATAATTTCT ACTGACCTAT CTTCAAGTTC ACTGATTCTT TTCTCAGTCA 4800 TATCTAGTGT GCTCAACGCC TGTTGAAGAA ATCCTTTGTC TTTAATATCA TGTTTTTTAT 4860 TTCTAGCATT TTCATGTAAC TCTTTGTTCT GGTTTCCATC TCTCTACTCA CTTTTTTTTT 4920 TTTTTTTTTT TTTTTTTGAG ACAGAGTCTC GCTCTGTCAC CCAGGCTGGA GTGTAGTGGC 4980 GCGATCTCGG CTCACTGCAA CTTCCGTCCC CTGGGTTCAA GTGATTCTCC TGCCTCATCC 5040 TCCCGAGTAG TTGGAATTAC AGGTGCCCAC CACCGTGGCT GGCTAATTTT TGTATTTTTT 5100 TAGTGGAAAC AGGGTTTCAC CATGTTGGCC AGGCTGGTCT TGAATTCCTG ACCTCAGGTG 5160 ATCCACCTGC CTCAGCCTCC CCAATTGCTG AAATTACTGG CATGAGGCAC TGCACCCAGC 5220 TCTGCTGACA TTTTTTATCT TTTGCTGCAT TTTGTCTACC TTTTCCATGA AATCCTTTAA 5280 CATAGTAGTC ATAGTTACTT TCAATTCCTT GTCTGACAGT TCTGACATTC AAGTCTAGGT 5340 CTGTTAATAG CTTTGTGAGT CTGTTAACAG CTTTTTTTCA TTCTTGTCTG TGTGTTTTGT 5400 ATTTCTTGAT TGTATGCCAA ATATTGCCTG TAAAATAAAC TTAGATAAGT CATACTTCTA 5460 TCCAGAAATA GGCACATTTT TTGTGTCCAG TCATTAGTGT GGAGGGAGGT TGGGGCAGTC 5520 TAGTCAGTGG CTGAACTAGG TTTGGATTTG TTGATGCTAT ACTTAGAATG CACCAGACTT 5580 CCATTCACTG CAAGAGTGGG CTGCTGCGCT TTGTGATTCA TGTGAGGCCT GAATTGTGGG 5640 TTTTTCCTTA GTGTGTCCCT CCATGCTCAG ATTTCAGCAA GTCTTCATAT CTGTGCCACA 5700 GAAGGAATCT GACCCATGCT CTTTTTGACC TCCCCAAGTG ATCAACTGTT GCTTGTTATA 5760 GCTTGTCATG GAGTAAGAGG GTGTTTTTTT AGTTTTCATC CTCCAGCCTT GGTCTTGGGC 5820 CCTGAGCTCC TAGACTCCAG GAGTGGATGG AATCCAGTGA TTTCTCAGTA ATTCAGCCCC 5880 TTCTCCAGTA GTGGCAGATC TCTGCTTTGT ATCAGTGCAA GATCCTGGGC TGAGCTCATT 5940 TTCTGCCCTT CCTCGAGTGG CAGACAGCTC TTGCTTTCAC CCTTCTACCA AAGGCAGTGC 6000 ATCTTTTCTT GGGCCTCTCC CCATTGAACT TATGACTTTC ACATAAGAGA AGGGCTCATG 6060 TATCAGAGAA TTCTGTGACT TTGTGCCACA TACAGAGTCT CTCAGTTCTC TTGCCCTGCC 6120 CCAGTCTTTT TTGTGAGCAC CTAGTAGAGA CCCTTGGAGA AGAGCAAGGA AGCGAGTATG 6180 GACTTCTTTT GTGTCTGTCG ATTGCTTTGT TTCTCAACTG CTACTCTTGG ACTTTAAGAA 6240 TTCATTAAAA TTTCAGCTGT TTTCTTTTAT TCTTTTTGTT TTTCTTTTTT TTTTTTTTTT 6300 TTTTTAGATG GAGTCTTGCT CTGTTGCCCA GGCTGGAGTG CAGTGGTGTG ATCTTGGCTT 6360 GCTGCAACCT CCGCCTCCCG GGTTCAAGCG ATTCTCCTGC CTCAGCCTCC CAAGTAGTTG 6420 GGATTACAGG TGCCCACCAC CACACCTGGC TAATTTTTGT ATTTTTAGTA GACACAGGGT 6480 TTCACCATTT TGGTCAGGCT TGTCTCAAAC TCCTGACCTC ATGATCTGCC CGCCTCAGCC 6540 TCCCAAAGTG CTGGGATTAC AGGCATGAGC CACCGCGCCA GGCCTCAGCT GTTCTCTTTT 6600 TACCTGCTGG GATGGCTAGT TTTCTGTGTC AACTTGACTG GGCCATGGGA TGTCCAGATA 6660 TGTAATTAAA CAGTATTTCT GGGTGTTTCT GTGAGGGTGT CTTCAGAAGA GATTTGCATT 6720 TGAATTGGTG AACTAAGTAA AGCAGAGGGC CCTGTCTAGT AGGGGTAGGC ATCATCCAGT 6780 CTGTTGAGGA CTTGAATAGA ACAAAAGGCA GGGGAAGGTT GGAATTGCCC CCTCTCTGCT 6840 TGAGCTGAGA CATCTATCCT GCCCTTGGCA CTCCTGGTTC TCAGGGGTTC AGACCTGGAT 6900 TCCTGGTCTC CACCTTGCCC ATGGCAGACT GTGGGACTTC TCAGCCTCCT ATCTAATTAA 6960 TAAATCTCTT CATACACACA CACACACACA CACACACACA CACACACACA CACACACACA 7020 CCCTATGTAT CCTTCTGTTT CTCTGCAGAA CCATATCTAA TACACCTGCT TTTATGACGA 7080 TTACCTATCG ATTCTGTATT CTGCCAAAAC TGAAAACAGT TCATTTTTCC ATCTCTTCTC 7140 AGAGAGGCTT GTCAGCCATT AGTTCTCTGA TGGGCTCAAG AAGTTATGCA GTTTTTTTTT 7200 TCTCACTGTT AGGATGGAAT TGATATTCTG TTGAAACTTT CTATACCTAA GTGGAAACTT 7260 GTTTTGAGGT TATTTTCTCT ACTTACTTTT GCTGGAAATG GAACACTCTG TATCTAGTTA 7320 AGACACATAA ACTGACTTGT GATACCATAA TGTTGTGTTG AATTTTATAT TCTTAGAAAA 7380 TCATCTGTCA AGGTGTTAAC TAATGGCAAA GCATTTAATA AATCAGCATT CATGTATTCA 7440 GGTGCTCTGA ATTATCTGAC TTTTAAATTC TTACTTTATA AATGAGAAAA TTGGGGCATG 7500 GAAAAGTTAA CTCTCCTAAC CCCGAATTAT TACATTATTA AGGACAGGAC TTAGAGGCCA 7560 GATATCTTAA GTCATTAATA TTCTTTGGCT CACAGAATTG GCAGTATAAC CTAAAGGTAA 7620 TAACTAGGTG ATTTTCTTTT ATATCAATTA AATATGTCAG TTTTCAAATA TTCATAAGTA 7680 CCTACTGTGC AGGGAAAGAA CATGCCATAC AAAAGATGTA GTCCAGGCCT TTAAGAAACT 7740 TTCATTTAAT GGGAACTCAA GAAGTGTACA TATAAGGAGG GAAGTAGCAG TATGGTACAA 7800 GATAATACAT ACATATCAGT GAATGATATT GCCAAAAAGT GCTATTGATA GAGAAATAAT 7860 TCATTTCTGC AAACAGCTGC TGATCTCCTA CTGAAAACAG AGGAGGGAGA ACAGGACGCC 7920 TCGTGGTCAG GATAGAAGAG AAAGACCTTG AGTTGAGCCT TGAACAGTAT TTAATATTCA 7980 AAAGGTTAAG AGAGGAGAGC AATTGAGGAG GGGAGAATAG TTCCAGCACA AATGATGGTG 8040 TACAAGATGA ACACAGTCAG TAAAGAGCAG ACTGGTCTGG ATGGAGAGGA GGATTTGCAT 8100 CATTTGGGAT TACGTCATTT AGACCCTTGA AAGCCAGGAT TGAGTAAAGC CACAGTGAAG 8160 CGACTGGCTC GTATGGAAGC TTTATTTTAA GAAGATTAAT CTGGTAGTGA CATGTGCCAA 8220 AAACTGAATA GGTAGAAATG AGATGCAGAG AGCCCAGTTA GAACTAAGTC TGGTGCAGTA 8280 ATGCAGGATT GAGGCAATAA ACACCAAACT ACAGTATCAC CAGATAATGG ATGTTTGAAC 8340 GGACGGTTTA AAGGAAAATT GATGGTATTT GGTAATTTAT TAGATAATCC AGGGCCATGG 8400 AATGAGAGGG GAAAATGACT AACCATAGTC ATCAAATGGT TTTTCTTAAT GAATCTGAAT 8460 TTTGGTGTAA GAGCAACATT TTCTTAGGCC TTGCCTAGTT GGTACAGCTG ACTATGATAA 8520 TGACTGCTAC CATGCTTGTT CCTCTTTTAG CAGCTGTGAG TCCCCCACCA GCCAAACAAT 8580 GAGCCTCTTG AAAAGGACGA TGCCTTTTCA CTTCTCTCCA AGTGCTTGGC AAATAGGAGG 8640 CCTTTTGAAG TTACTTTATA GTTAGGGGTT CCCAGTGAGT ATTTGAAATA TTAAGTCATG 8700 CCCGTGGTTG ACAGCATGGC CCTACTGCTC ATCATCAGCT ATTAACCTTA GGCAAGTTAA 8760 TGAACTTTTC TAAGCCCCAG TCTACTCATT TATAAAGTGG GATTATTAAT AATGTCTACT 8820 TCATAAAATT ATGAAGCCTG AGTTAGGTCA TTCAGATAGT GTTTAGTCTG ATTCTTCGAA 8880 CCTAGTAAAC AGTCAGTAAA CAGAAGCAAA TGCCACATGC CTGATTTATA TCCAAGGGGA 8940 GAAAGGTAAA AGTGAAATTT TCATGATTTA TGGATTCAAA TTATACATTT CAAAGATGCT 9000 TTATAAGCTA TTGTTTTGGT AAGAAGAATT GAGCTGAAAC AGAATTTTCT GACAGCAGTG 9060 ATTATTAAAT GGTGAAATAG GCTATTGATG TCTTTAGAGG ATATAGATGT TCACCTTTTG 9120 CATATAAGTG CACAAAAATT CACTAAGTAG ATATGTCTGT CTACACAGAG AGAGAGAGCG 9180 TGAGAGCATT AAAGTTAGTA AACATCCCCC TCGCTTTTTT TTTTTTGAGA CAGGGTCTTA 9240 CTCTGTTGCC TAGGCTGGAG TGCAGTGGTG CAATCGTGGC TCACTGCAGT CTCAACATCC 9300 TGGGCTCAAG CGATCCTCTC GCTCAGCCTC CTGAGTAGCT GAGGTGTGCA CCACCACACC 9360 CGGCTAATTT TTAAATTTTT TTATTGTAAA GGTGAGGTTT CACCATGTTG CCCAGGTCTC 9420 AAACTCCTGA GCTCAAGCAA TCTGCTCACT TCAGCCTCCA AAAATGCTGG GATTACAGGC 9480 GTGAGCCACC ACGCCTGGCC AGTAAACCCC ATTCATTTAC ATCATCTTAC TTGTCCCTCC 9540 AAAATCCTGC AAAGTAGGTA GGTTCTGTCT TTATTTGTTA TTTAGGTGAA GAACTTGAAG 9600 TGGTGTTGAG GAATAGGTGT TTTGCCAAGA GTCACGCAGC TGGAGTGGCA GAGCTGTATA 9660 CTCTTCTGAT TCCACCAACG CTGTTTACAT CACATCTGGA GAAAAGTGCT CTGAGGCACA 9720 GATGTTTAGT GGGAGGGATG AGACACAGGC TGCAATGCCT AAAGATAATC GGGAATAAAA 9780 GCAGAAAACA AGACGTTTGT TTCTGTTAAA ATGAGACAGA AAATAAGGCG TTTGTTGTTT 9840 GGGATTGAGC ACTTGGAGAA GTGGGGAGCG ATTTGATTTG GGTGAGACTG CTCCTGGAAT 9900 GCTGCATCTG GTTCTGGACT ACTCATTACT AGGCTTATAG AAACTAGCTG GAGGAGGTTC 9960 AAAGAAAAGC TCCAAAATGA TTAGCGGGCT GACGGGATTG ATTTATAAGA AATATTAAAA 10020 GAATTAAATG TGTATAGCTC AGCTAAGCAA AGATGAAAGA GACCAGCTAA ATGTATACAA 10080 ATATCTGAAA CGTGCAAACT TTAAAAAGAG AGATTAATTA TTTAACATGA TACACGGGGG 10140 CACAATATGC AGTCACAGGA TGAAAATTTC AGCTGAGTAT CTAGAAGAAT TCCCCGATAG 10200 TGAATCTGTT AAGGCTGTCT GTAGTGTGGC CTTTCCCTGG AGAGGCAATA GAAATTTCAA 10260 GTCTTACGAT TTTAAAAGTT TCTTGGGAAC TAGGTATTAG ATGATGTTAG AGAATTATTA 10320 TTAATTTGGT CAGGTATGAT AATGGTATTG TAGTTCTATA AGAAAAATTG TATTTTTTAG 10380 AGTTACATAC CCTGAAATAT AAGCATAGAA TATGATGTAG GAGATTTGCT TTAAAATACC 10440 ACAGTAAGGA AAGAAAGGAA GGAGGAAGAA AAGAAAGGAA GGGGAAGAAA GGGAAAAAGA 10500 GGCAAAGAAG GAAGAGAAGG TAAGAGAAAG AAAAAGAATG AAGGAAGAAG GCTGGGCACT 10560 GTGGCTCATG CCTATAATCC CAGCATTTAG GAGGCCAAGT TGGGAGGATC ACTTAATTAA 10620 GCCCAGGAGT TCAAGGCTGC AGTGAGCTGT GATTGCGCCA CTGCACTCCA GCCTGGGTGG 10680 CAGAGTGAAG CCCTGTCTCT AAAAAAAAAA AATAAGTTAA AAAGAAAGAA AAGGATAGAT 10740 GAAGTATGGC AAGATGTTGG TAATGTTGAA CCTGAAGGAA GTTAATATGT GAGTTCACTT 10800 TCCTCTTCAG TCTTCTTTAT GTATGTTTGC CAACTTTCAT AATAAACAAT TTAAATTATA 10860 TTTTCCTGAT CAAAACTTAG TAGCAGTATT AATCCCTGGG CTTCCTGACT AGAACAGCCT 10920 CATTACCACA TGGGCAGAGT TCTGGCCGAC CAGGGACCAC GTAGTGGTTC ACCATCTTGC 10980 TCTGGTAATG TGGTCTGGGC TGAAGGGCCC TTTCTAAGGT TGTAGATAGA AATCCAGGAA 11040 ACTTGTTAGA ACTGCAGACC TATCAGGGTA CCTGCAGGAG GTGAGTCTAC TAAGGTGAAA 11100 AAGCAGAGGG CAGAGGTCGT GATTAGCAGC TGACCGCCCC CTGCTTTTCT GTCCCTCATT 11160 CGTGGAAAAT TGAGTGGAGC TCAATTTTGA GTGGAGCTCT AAGTAGCTCC ACTTGTAGAC 11220 ATTGAGTGGA GCTCTAAGTG TCTTCAGAAT AGCAAAACAC TAGTTTTCTT TTTCTTTTCT 11280 TTTTTTTTTT TTTTGGAGAC AGAGTCTTGG TCTGTCGCCC AGGCTGGAGT GCAATGGCAC 11340 GATCTCCGCT CACTGAACTC TGCCTCCCGG GTTCAAGCGA CTCTCCTGCC TCAGCCTCCC 11400 GAGTAGCTGG GATTACAGGT GCCCACCACC ACGCCCAGCT AATTTTCCTA TTTTTAGTAG 11460 AGATGAGGTT TCACCGTGTT GGCCAGGCTG GTCTCAAACT CCTGGCCTCA AGTGATCCGC 11520 CTGCCTTGGC CTCCCAAAGT CCTGGGATTA CAGGTGTGAG CCACCACACC CAGCTGCAAA 11580 ACCCTATTTT TCTTGAATGG AGAAACACTT TCCCCTTATT TATTGAGTTT GGGAAGCAAG 11640 AAGAGGGGTA ATTCATTAAG TGAAAATTTC CAAAATCCAG AAAACATCGA TAAAGCAGCA 11700 GCTTAATTTT TTTAAGGAAG AATTTTTTAA ACTATCTTCT TTTGAGCCTC TTTAGGAAGA 11760 CCTCACGTCC TTGCCTTGAA TGTTGAGAGT GGGAAATCCA GGGAGTTTTG GAATGCATGC 11820 CTTATGTCTG CTTTTTTGTT TGTTAGAGAA ATATAAATAT TTTATCTAGG TTTTGCTGAT 11880 GGCAGTCAAG CATGAACACA ACCCACTGTT TGAGAAGCTG TAATTTCTGA ATTTCTGCAG 11940 AGTGCACATC TAGGCCAGCA AATGGCAGTA AGAGTGAGGT GGATTTAGCT CAGTGTAAGG 12000 ATGAACTCCA GAACCATCGG CTCTGACTGA AAGTGAAGCG GCAGCCGCGT TGTGGGAAAG 12060 CTGGCTGGAG TCTCTCTCAT AAGCAGGCAT TCTTTTTCTC CAGCCCGTCA CTGTGTTGGT 12120 TTGGGCCCAC GGTAAGCCTC CTGGCCTCTA GGCTGTAACC CCCACCATCC TCCTCTGCCT 12180 CGCCTCCAGA GTGATTGTTC TGAAGCACAA CTGGATGTCA TTCCCCTTCC TGAACTCCTA 12240 GCACCTACAG GGACTCCATC CCTTGTGCCC CACATACCTC ACACGTAGAC ATTCCTAATG 12300 AAGATTTGAT TGAATTATTG TAAACTCAGT GCCTCCCACT CTTCTAGTTG CCTCTCTGCC 12360 TGCCTTTGTA CATTTATTTA TTTATTTATT TATTTATTTA TTTATGAGAC AGAGTCTTAC 12420 TGTATCACCC AGGCTGGAGT TTAGTGGCAC CATCTCAGCT CACTGCAACT TACCTCCCAG 12480 ATCAAGCAAT CCTCCCACCT CAGCCTCCCG AGGAGCTGGG ACCATAGGCA CGTGCCATAT 12540 GCCCGGTTAA TTTATTGTAA TTTTTGTAGA GATGGGGTTT CATCGTGTTG CCCAGGCTAG 12600 TCTTGAACTC CTGGACTCAG GCGATTCGCC CGTCTCAGTC TCCCAAAGTG CTGGGATTAT 12660 AGGCGTGAGC CACCATGCCC AGCCGCTAGC ACTCATCTTA ATCGTATATT TACTTATCTG 12720 GCTTTCCCAC CAGACTGCGG GCTCTTCAAG AGTAAATGCC ATGTTTTCAC CTTTATTTCC 12780 CCAGTTTGTG GCACATTCTA GGCACTCGCC ATCATGAAAT AAACCTCTGG AGCTGTGATA 12840 TTACAAACGT GGAAAGATGA CGAGCACTCA GCAACTTTCA GTGAGTAAAC AAAGGCTTTC 12900 ATTCAGCATG ATTTATTGAC TGCCCAAATC TGGGCTGCTT CCTGTCTGTG GTTCAAGGAG 12960 AGCATAGTCT ACAGAACCAG AGACCTGGCT ACTCTGGAAG TTAGACTTAA GCCCACCCCG 13020 GTCCTTGAAT GGGGAAATAT TTCCCTTCAT TCCTGTGTTT TAGGGACAGA AAGATGAGTA 13080 ATGCAGTGAT ACATGCTGGA AATGTTTATT CCACTACCCG AAGCTGCCTC TCAACTTAAC 13140 AATCCATGAA AGAAACAAGA TGGTATATAA CTTTTTCTAA TTTGTGATGC CTTTGTTTAT 13200 TTGTTTCCGG TTAAAAGAGG AGGTGGCATT GAATTGTTTG TTTGGTTTGG TTTCTTCTTC 13260 AATAAGAAGC ATCTTAATAT AACTAGACTG GACATCTGTC CCATTTTCAA AAATTACAAG 13320 TTTCGATCAT TGCTAAATTG TACAGATCCC AATCTGTCTG CTCTGCATAC ATTTGCATTT 13380 ATAAAAGCAG AAGCAGACTA GCAGTCTTTC TAATGCAATC CCCCAAATGC ATGAAGTATT 13440 AGATTGCTTC TCCCTATTGG TTCATGCATT GCTAAAGGCT TAAAAGGATC ATTGATTTTA 13500 ATTATTTAAT GTGTACAGCA GGCTGAGCTT CCTTTCTTTT TTAAGGGAAG AACCTTCAGG 13560 GGCATTGCTT TAGTTTTTTA ATGTTAAATC TCATTTTTCT TTGAAAATAA GAAGTTAAAG 13620 CTGTATTCAC ACAAGCTCTC AAAGTGCCAG ATTTTCATTG TGTTTTTAAA CCATCTAGGA 13680 AATGTTTGAT TCTAATGAAA CATTACTGCT GAAAATTGGG CTGAAATTGC TGGGCTGGAA 13740 ATATTGTTAT AACTTCACAT GATTCCAGTG TTGTATTATT ATTTTTTCTT TTTCTTTTTT 13800 TGACCCGATA TAGATGAAGC GAAGAGACAA GGAGCAATCC CATGTGTAAT AGAAAAAGGC 13860 AGCCTGAATT GTTGTTGCTG TTTTTGAAAT TTAAGCTGGT TTTCGATTAA ATTCAGTAAA 13920 TGGTCCAGGA CTATAAATGT TGAACATTTT TTACCGTGTG ATTTAAATTT TAGTCTTATT 13980 GTTTTTTTTT TTTTTGATGG TTTACATTTT CCCCATGGGA AGCAGCTATG TCATGTCGGC 14040 ATGATTCATC ATGGTAACAT CTCGGGTTAT TTTGGTTTGT GTTATGTTCA GAAAGCGGAA 14100 TGCCAAAAAT AAAGAGTGGT TTGTGATGTC TAGTGTGTCT TCCTTTAACA AATCAAAGGC 14160 TTTTATTTAA TCCACTTAAT GGGACACTGC AGAAATTTAA AAAATGGAAG TCCCATCCAC 14220 AGAAGGCAGG TACTATGATG TAAAAAGTTT AGGTGGGGGA TTAATAGAGT GATCATATAA 14280 TTTATGAGCT AAACCGGAGG CACTTTTTTT TTTGAGATCG AGTCTCACTG TTGCCTAGGC 14340 TGGAGTGCAG TGACGTGATC ACAGCTCACT GCAACCTCCG CCTCCCGGGT TCAAGCGATT 14400 CTCATGCCTC AGCCTCCTGA GTAGCTGGGA CTATAGGCGC CCACCACCAT GCCCAGCTAA 14460 TTTTTGTGTT TTTTGTAGAG ATGGGGTTTC ACCATGTTGG CCAGGCTTGT CTCAAACTCC 14520 TGACCTCAGG TGATCCGCCC ACCTCGACCT CCTAAACTGC TGGGATTACA GGCGTAAGCC 14580 ACCATGCCTG GCCCAGAGAC ACTTTTGAGA GTGAAGAGGA AGCTGAGAAT AATTCACTGA 14640 TCTACAACTG GGACCATCCA GGGCAAGCCA GATGCCATTA CCACTAGCTA GAAAGCTTGC 14700 CAAGGTCTCA TTTACCTTGG TATATAGCAA ATTCTTCTTT TGAATTCTGG AAATTCTGGT 14760 AAGTCATTGA GGTAGCTCTG TGCCAAGGAG CAATATGGTA GAATTCTAAT ATTTCAGGCA 14820 GACAACACTT TCCTGCATTT GTAGCAGGTA AAGGGAGGTC AGGGCAGAAG ACAAAACCAC 14880 TGGGACTCGA CAAAGGGCAT AAACGTCTAA TGCACCTGAT GTAGCTGATG GTAAATTGTT 14940 ATCAGCTAAA GATCTTTCAT AATAAATAAA CTTATCATTT GTAGGAGGGC ACAGAAATCG 15000 TGGAAAGCTG GGATTCAGGT TGCCTGTGGC TTTAATTCTG GAATCAGAAA TATTAGTCAA 15060 GGATATCAGT CTATGAAGTA AGTTTTCAAT GTTATATGCC ACAAGATGCA GCTGTCCTAT 15120 TTTCACTTCC AGTAATTCCT TCTGAATTAA TACACCTTAA AAATAGCTGC AGCTTCTCAA 15180 ATCTGTGAGA ATCGTATGTG CTGCTTGCTA CACTTTCTTT TTCCTGAAGG CTCTTTGAGG 15240 TCTTTCAAGA ACTCAATTCA ATTCAGCAAC AATTAGGGGG TCTAAGGTAT ACAGACGCTG 15300 TGCAAGATGC TCCTGAGACA CAAAGAGGAG GTCAAGCCCC TGCCTTCAGG CACCTCTCTA 15360 TAATATAGGA GGAGAAAGAG AAGAAACACT AATACACATA GGTAGGTGCC ATTAAAAGGG 15420 TACATACATT AAAGCCAGGT GGTAGGTGTA AGAAGATTTG TAACATGAGA ATTTTCTGCA 15480 TGTTTGAAAT ATCTTATAAT TTTTAAAAAT TAAAATGGGA GATACATATA TATGTATTTA 15540 TGTATGTATA TATGTATGTA CATATACACA CATATATACA TAAATATATA CATAAATATG 15600 TATATATGTG TATATAGACA TAAATATGTA TATATGTGTA TATATACATA AATATGTATA 15660 TATGTGTATA TAGACATAAA TATGTATATA TGTGTATATA GACATAAATA TGTATATATG 15720 TGTATATAGA CATAAATATG TATATATGTG TATATAGACA TAAATATGTA TATATGTGTA 15780 TATAGACATA AATATGTATA TATGTGTATA TAGACATAAA TATGTATATA TGTGTATATA 15840 GACATAAATA TGTATATATG TGTATATAGA CATAAATATG TATATATGTG TATATAGACA 15900 TAAATATGTA TATATGTGTA TATAGACATA AATATGTATA TATGTGTATA TAGACATAAA 15960 TATGTATATA TGTGTATATA GACATAAATA TGTATATATG TGTATATAGA CATAAATATG 16020 TATATATGTT GTATATAGAC ATAAATATGT ATATATGTGT GTATATAATA ATGTGTGTCA 16080 TATACACACA TATATACATA CATAAACATT CTGCATTATA CCATTCACTT TGTAACCCAT 16140 CTTCCCTAAA AACTGTCTCA TAAAGAGTCT TCTTTTCCCT GTACCTATGC AATGGTAAGT 16200 AGCAAAACAC ACATTCTTTT GGGTCCCCAT AACATTCCCT GTAGTTTGCC CTTAACAGTC 16260 TTTGATGTGA AATTTACTGT TTCTGTCTTA ACCTTGCCTG TCTCGCGTAC ATGGAGTTTT 16320 GGCTCCTGGC TCCTAGTCTG CATCTTCACC CCATCCCTTG CCCAAAGAAT CTGGTTATGT 16380 GACCACTGCT CATCTTTTCT GCTGCCACAA CTCCAGTCCA AGCCACAAAC CTCTCTCTCC 16440 TGGACTCCTG CGGGGAGTTC CTTTCTCTCC CTGCATGAGT CTATTCTCCG CACAACTGGC 16500 ATAGGTAAGT GAGACTGCGG AAGAGGCAAG TTTGCAAGTC CAGAGGAAAT GAAGACTCTG 16560 CTTGTGCACA TGCTGGGTTT GACGGGTGCT GGATATCCGA TGGATGGCCC TTAAGGTGAG 16620 CTCAAGGCTT AAGGGAGAGA TAGGGGCTGA TGATCTGAGA TTCATCAGTG TGTGGCTGAT 16680 GTTTAAACCC AGGGGACAGG ATAAGAAGGT TATTCCAGGG AGAGCGTAGA TAAAGAAGCT 16740 AAATGGCTTC TGGGTCCTTA GTCATTCAAA ATCGGACCTC TGAGGCAGGA GGAAAGCCCA 16800 GAAAGAGTAG ATTCCTGGGA CTCACGGGAT AAAGACTTTC AAAAAGTGGG GGCTGGCCAG 16860 TGCTGCTGAA GGAAGTAGCA GGACCGGAAC AGAAGGGTAA TCGTTGGACC TGGAGAACTT 16920 GAATTTGAAT TTTAAGGTTG GTAACCTTAA AAAAGAGCAA TTTTAGATAC CTTTTGAAAT 16980 TATTTGCAAG ATTTGTTTGG TATATGTGTT ATTCCAGGCA AAGGGACCAG AAAAGTAAAA 17040 AATACTTACT GAACAGTTAC TGCATGCCTG GCACTGTAAC ACCCTGTTTA ATTCTCACGG 17100 CAACCCTATA GAGTAGGTGT CATCATCCCC ATCTTACAGA TGAGGATATG AGGTGCAGCT 17160 AGATTAAGCA GTTTGCCTCA GGTTACACCA ACTGGTTAAC GTAGAGCTAG GATTTGAACC 17220 CGGATGGGCT GATCCCAGAG CTCATGCTTT AAATCGCTAG ACTGGTGCTC ACAGAAGACT 17280 GGGACCGAAA AAAATTAATA AAAAAAATAA GGAGCCCCCT GGGCTAGCAA ATTAGGAGTT 17340 GTTCAGACAG ATGTGAAAAG GAAAGCAAGG CAGAGGGAAA GTCACTGTAC AGAAGAGAGA 17400 GACCCATGAC AGCAGAGACA GTGAGCTGGT AAAGTGGCTG GCGATCTAGC CCCTGAAAAT 17460 ACCTCCAGAG AGGCAGGCTC ACGCCTGTAA TCCCAGCACT TTGGGAGGCC GAGGTGGGCA 17520 GATCACCTGA GGTCAGGAGT TTGAGACCAG CCTGGCCAAT GGCGAAATCC CGTCTCTACT 17580 AAAAATACAA AAATTAGCCG AGCATGGTGA CAGGCACCTG TAATCCCAGC TGTTCAGTTG 17640 GCTGAGTCAG GAGAATAGCC TGGATCCGGG AAGTGGAGGT TGTAGTAAGC CAAGATTGCG 17700 CCACTGCATG CCAGCCTGGG CGACAGAGCA AGACTTTTCT TAAAACAAAC AAACAAAAAA 17760 GAAAAAAGAA AAGGAAAGAA GAAAGAGACA AAGAAAGAAA GAGAGAAGGA AAGAAAGGAA 17820 GGAAGGAAGA GAAGGAAGGA AGGAAAGAAA GAAAAGGAAA GAAAGAAAAA GAAAGAAGAA 17880 AGAAAGGAAA GAAAAGAAAG AAAAAGAAAG AAAGAAAATA CCTCCAGAGA GCCAGGTCTC 17940 TTAGGCCTTC TGAGAAACTC ACATCCCTTT TGATGAACAC AAATGCTTCA CACTCTCAAT 18000 GTTATTGGTA ATCCAAGTTA TCAATATACC TAAATCACTT AGTACTGAAT CTGGCATATA 18060 GTAATCACCT AATGAAGAGA TAAGAGTCAT GGAGTATTCT GAAGCAATTA GAATCAATAG 18120 ACTCAATATA CACATGGCAA CAAAGTTGGA TCTTAAAAAC CGACCTGAGT GAAAAAGGAA 18180 AGGGAAAGAT ACATAACACG GTACCATTAT GTAAATTGAT AATATATGCT TACACAATTT 18240 GTAAGAACAC ATACAAATAG ATACATGTAT ATTAAATATA CTCGAACGGT TACCTATGGG 18300 GTGGTGGCTG GAGTGGGGGT AAGTCCGTAA GCTGTAATGG AACCTAAACA AATACATGAA 18360 ACGAGTAGGA ATCAGAAGGA GTAACAATAA AAATGTGCCA TGAACTGAGG AGTGTAAATT 18420 AATCAACTCA CTGCATCTGA GGTTAAAAAT AGAAAGATGA TAATTGTTAT TCTTATTACT 18480 CGTAGGTCTT CCACTTGCAC TCAGCTTTAC AATGTTGGAC TATCCTTCAG ATGGCACCCT 18540 CCTTGCACTT GCTCAGGCAG GAGAGCTTTT TCCTCCAGCT TTCTAGGTGA TTTAATATAT 18600 CAGGGAATAA GTATAAAAAA AGGCACGGTG CTCCCTGGGT AGCCTTTCTG GACTTCAGAG 18660 CTAAATTGCA AAGTCAGTTT TACACATGTG ATTTCATCTA TGAAATTAGG GCAAGGTAGA 18720 AAACTGGCAC AGAAAAAATG TGATTTATTA TGGTGTTACT ATCCCTTACA AGCGGAGTGT 18780 CAGCTGCCTC TTTTTGTCCA CTGATTTAAG GCAAGATGAA CTGAAAGTGG CTATGATCAC 18840 GTCTTCAAAA GCACACTCTG GCCCCTCGGC TGCAGGCGCC CTGCACATTC CCCAGCTGCG 18900 TGTCCGGTGG TGACACAGTG CATAATTGTG GCGCCTTCCT GGTGCAAACT GTCTCACTTA 18960 GCTCCGTCTT GCTGGCACAG CAGAAAGGAA GAAATCGAAA ATGTTTGGAT TTCAAAGGTA 19020 ACAAGAAGCT GGAAAACAAC TACTGGCCGA GTCTGAGAGT TTCAGCGGAG ACTGGTGCAG 19080 CCTTGTGTTT TTCCACTGAC AGCTGAAAAT GAGCCCAGCT TCAGTGAAGC TTGTTTCCTT 19140 CCCTCCTCAA GGTTACCCAC AATTCTCAGT TCTCTCAGGA AAGCCAAAAA ATGAATTTGA 19200 GGGTTTAGGA TTGTGGTTCT TTTATCTATT ACAGGATTGA TAATATGTTC CTCCACCAGA 19260 TGTTCTGCTT GTAACAATAC TCACTTCCTG ACACTACTGC ATATGCAGGA GTGTTACTAC 19320 CAAGGTAAAC ACAGAATTGG CTGCCCAATT CCAAATCCCT GAACTGAGTG AGAGAAATCA 19380 GAATTATAAT AGGGGATTCA ACAGAGCTGG CTACGGATGT GCCAGTGGTC AGATACTTTG 19440 CTCATCATAC GCAGGTGCTG CTGCTCTAGC AACTGCTCAC TGCTTCATTT CCTGCCTTGG 19500 TCTTTAAATA CTGCTTTTCT CAGCTCAATT GGCTTTCTTC CCTCTGGCAG TCACGTTTCT 19560 TTGGGTCAAA CAGCAAATGA TTCTTTAGAA TCACCTGGTA CTCAAAGGAG CTACAAGACA 19620 TTGGGCATCC ACTTCCACTC TCTTGGAAAA ACAATTTTAT GGAAGCCAAG GTTGCCATAG 19680 TGCCTCTTGA GGTTGTTTGC TCAGCCAAGG CCCAAGCTTT GTGCTTCAAA CATGAAATTA 19740 GAGAGCTTCA GAACAAGATC CACATTTTCA ATGGCCTCAC CCAACTGGAT AAAAGAACAA 19800 TTGCCATATC TCAATGACCA CCTTTTTCAG GTGGGATGGT AGATGCTGGA ATGGGTCACA 19860 GCATTGCCCA ACCAAACTTT GCAAAAAAGG CTGGAAGCTC TGACTGGGGA CCCTAAATAT 19920 GCAAAAGTTG ATAGGCTCTT CATGCAGAAT ATGAACCCCG TGTATGGATA TAGCTAAAGG 19980 GTTGGCCTTT ATGTTTCTAT TCCTTCACAA ACCTGGTAGA ATAGATATGC TTGTTTCCCT 20040 TTAAAAAATG TCAACAATTG CATTTATGAT GCTGTGTATA GTAACTCACA GATCATGCTC 20100 CATGAAAATG CTTCAGAACC CAATATAAGG AGATTTTTTA GCCATGTGTG ACAAAAGAGA 20160 GGCCATTTCA GTGTTGAAAT TGTTCAGAGA AGTATTTGAT TATGTTTTCT CAGATCTTTT 20220 TATTTTTATT TTTTTTGAAA CAGAGTCTCA CTTTGTCACC CAGGCTGGAG TACAGTGGCT 20280 GTGGTCTCGG CTCACTGCAA CCTCTGCCTC CCAGGTTCAA GCGATTCTCC TGTCAGCTTC 20340 CCGAATAGCT GGGATTACAG GCGCATGCAC CACCATGCCT AATTTTTGTA TTTTTAGTAG 20400 AGACAGAGTT TCGCCATGTT GACCAGGCTT GCCTTGAACT CCTGACTTCA GGTGATCCAC 20460 CCACCTCAGC CTCCCAAAGC ACTGGGATTA CAGGCATGAG CCACCGTGCC CAGCCTGTTT 20520 TCTCAGATCC TGTATTTGTT TCTGAAGCCT TCATTTCTAT CTTCTTATTC ATTTTGGAAG 20580 TAGTACACCT AAGTAAGGTT TTTAACAATC AAATATCTTT GGAAAATTCC CTGGTTCCTT 20640 TCTTATTCCT ACAAAAATAT GTTCAGTATA GCTGATGTTA TGTTTCTTTC AAATTATTCA 20700 TTTCTCTATC TCAGAATTTA TCTCATGCCT AATTGTTATT GAATAGTCTT CACTTCTTGT 20760 CATCCAGTTT CTGGTCTCTT ATTTCACTCT AAGTCTAAGT GGCTATTAGA ATAAAGAGCT 20820 TGTAACAGAT TCTTTCTCCA ATATGTCTTA TCTTTTGACT GCATGCCAGT GACAAACTGT 20880 TAACTGTTTT GATTCTTCAT AACATTCCAC AGAACATGCT GACTCCTCTC TTCCTGAAAG 20940 CAATGCCCAA GCACAGCATT GTTAGATAGT ATGTACGCAA CAGGGACATG GGTGCATAGC 21000 AAAAACTAGA AGGAAGGAGG ACCTTCCTTA GCAATGGGTG ATATGGTCCC TGGACTTAGA 21060 CTCCAAAGGG TCGTGAGGTG AAACACACAT CGTCCATACC CAGGAAGCAC ACAGGTGGGA 21120 TGGAAGAGCT GTGCCTAATG AAACTTCATC CACGTGGAGG TGGAGGAGGC TGCAGCTGCA 21180 AGAACTCAGA GCTGCCTTAC CCAGACCAGG GACCAGGGAG GGCTTTCTGG AGGAAACAGC 21240 CTCTGAACTG CCAGCTGATA GAGGAGCTCT ACCTCAACTC TTCTGGTTCC CCAGGGCTGC 21300 TTTTCCACGT CCATTTATTG GCACTGAAGT TTGAATACCT TCAGGGGCCC GAAAGCCTGC 21360 CAGGTCCTCT TCTCTGCAGA GCAATCACAC CAACCTGCAA AGGGCTAGGA AAGGGCTGTC 21420 ATCATCTCCT ACTCAGAAAC TGGTTCACTG GAAGGACTCA GGGGCCACTG AATACATCCT 21480 GGCAGCTTTC ACAAGAAGGG CTTCTGACTC AAGGATGTTT CCATCTTTGC CAGGTCGCCT 21540 TTTCTCCTTC TCTTAGAGTT TGGAGGACGC AAATGTGCTG AGAAGTCAAC CTTTCCTGCA 21600 AGGTGAGACA CAAGGGCCTT TCCCAGCAGA AAGAAGAGAG CAAATGGAAG GTCCTTCTTC 21660 CTCCAGTAGA GGATGGACTC TGTCTGGCAG CCACCCAACA GGAAAAGCAC AATGCATGCC 21720 TGCCTGCTTC CCTCCCTCCC TCCGTTTCTC CCTCCCTCCC TCCTTCCTCC CTTCCATTCT 21780 CTTCCCTTCC CCTCCCTTCC CTTCCCCTCC CTTCCCTTCC CCTCCCCTCC CCTTCCCTTC 21840 TCCCTCTCCT TCCCTTCCTC TTCCCTTCCT TCCTCTTCCC TTCCTTTCCC CTCCCCTTCC 21900 TTTCCCTTCC TCCCTCCCTT CCTCCCTTCT TTCCTTCCCT TCTTTCCTTC CTCATTTCCT 21960 CCCTTCCTTC CTTCCTTCCT TCCTTTCTTC CTACTTTCCT ACCTTTAGGG CTCTGTGTCT 22020 TTGGAGTCCA TTCTGATTAT GCTGTAATGT CTGCCCCTTC CTCTTCTCTG TCAAAAAATG 22080 AAAGACATGG AAGCCACTTG CCTTTTACTG AATTAAAAAT TAGTAAAAGA GCTAAAAATT 22140 AATGGTTAAA AATGTACGCA TAAATTATGC AGTATACTAA CCAATGAAAA GATACACTTC 22200 TCTTAATTAA AAGCTGACAG GGAGGGAAAC AAGAAAAGAG AAACACAAAA CAATAATCTA 22260 AATGACCTAT TAGTTGGAAG AACAACATCA GAGAAAATAG ATACTGTGTA TAGTCATGTG 22320 TATGTCTATG GAATAACATT TGTAGAGAAA TCTGGACTGA TCCTTTCTGA GTAAAGAGAG 22380 CTGTGGGTAC AATTAAGGGG AGATTGAAAG GAATCCAAAA GCATAGCAGA TGCTGTGCCT 22440 CACTGGAATG GTTGCCGATC TCCTCCAAAC TATGAAGTGT TTGAGGCTCA ACTTTAATAT 22500 AATTAAGATA CAAAGACAGA ATGAGAGAAA GAGAGAAGGG AGCTCACTGG AAGAACACTC 22560 AAGATTCCTT ACTACTCATT CTCTAAAATT ACAATTGTTC TAGATGGAAA AGAAAAAAAG 22620 CTTCTCTGTT AAAAAAGGAG CTTGTGCTAT AGGAGGTTTA AAATATACTT CTGACCCATC 22680 TCCAACATTC TAAATCCTTC CCAGAAAAGT ATGCCAATCC CAAGAAATAT TCAATCAAAT 22740 TGCTGGAAAG AAAAATACAA AATATTAAAA TGTATTAGGA AGCGACAGTA ATTAAATCAG 22800 AACTGGAGCA GGAATAGACC AGCAGATCAA TGAGACAGAC ATCAAGTCCC GGAATGTGGA 22860 CTTGCAAATG CATTAAGTAA TATGATATGC AATAAAGGTG GCACAGTGAA CCAATGGGAA 22920 AAAAATTAAT CTTATAATAA TTGATATTGC AATAATTGTC TAGTAATTGG GGGAAGAAAT 22980 AAGCTTATTC CTTATCTCAT TTCTTTTTTT CTTTTTGAGA CAGAGTCTCA CTCTGGTAGC 23040 CCAGGCTGGA GTGCAGCGAT GCGATCTCTG CCCACTGCAA CCTTGCTCTC CCGGGCTCAG 23100 GCGATTCTCC CACCTCAGCC TCCCGAGCAG CTGAACTACA GGCGTGTGCC ACCACTCCCG 23160 GCAATTTTTT TTTCCATTTT TAGTAAAAT GGGGTTTCAC CATGTTGCCT GGGCTGGTCT 23220 TGAACTCCTG GGCTCAGGCA ATCCACCCGC CTTGGCCTCC CAAAGTGCTA GCATTACAGG 23280 CATGAGCCAC CGCGCCTGGC AGCTCATTTC TTAGACTAAA TAAATTGGAG ATGGCTAAAA 23340 GATTTCTATG TAGGCCAACT ATGTTTTTAA AAAGTTTTTT TTTTAAGGAT ATCTGCTGGA 23400 ACCAATCATG CCACCAACCA AAGATGCAAG ACTATAAAAC ATACCCAGTT TTTCAAAGCA 23460 TTTAAAAATT ATTCTAAAAA TATTTTTTCT CCAGAAATTT TGCATTGATT CCCTGAAGAA 23520 GCATTAATAT GGGACCTGAC TTATAAAATG ATGAACTCAA TCTCCCCACT CAAGGTAGGA 23580 GTCTCTCAGA TTTAAAAAAT AAGCATCCTA GTCCTCTTGT CCCTGTAAAA GTTAACCCTT 23640 ACACCTGAAA CACCAGGAGA CTGGCGGTTG TTTGCATAGG GGTTACAATT AAAGTTGAGC 23700 TACCTCTGAC ATCTATTAAC ACCAAAATTA GTAAACTATG CATGTATGGA GACTTTTATG 23760 ATTGAACTTG TTTATTGAGT CAAGAGATAT AGTTTACAAT GAAAATTTGG GGCATATCAA 23820 AATGACCTTG GCTTAGCTTA GCATTTGCTG ATGTTAACTA TTTTCTTCAT TGGGCTGATT 23880 TTAGTTGCTT AGGAAAAATA CAAACACACA CACTTTAAAA TTATATTAAA ATCCCGTCCT 23940 AAACCTCAGA GTCCAGAACC GCATCCTAAC ACTGGTCATG CATAATATGT TTAAATTTTT 24000 GTGCTTTAAA AACTACAAAT AAGGAATGTA TTAATAGTTC CACAATCAAT GGTCAGTTAG 24060 CCGAGGGAAG ATTAGCATAG TTAAAGACTT AAAATGGCTT TACAACATAT ATCAAAAGGA 24120 <BR> <BR> <BR> <BR> <BR> <BR> CAAAATAAGG GGAACAGAGT CTAGAAATGA GGAAACTGGG ACACAGGCAA AAAAAAAA A 24180 TGAGAACTGG GACATGAATA ACGCAAGGGA TAAGACTAAT ACACAAAACA CCCCAAATAA 24240 ATAGCCAGCA TTTGCTGAGC TCTTACTGTG AGCCTGTTCT AAGCACTTTA CATATATTAA 24300 CTCATTTCAT CCTCAAGGAA CCATCTGAGG CAGGCACTGT TATCATCTCC ATTTTACAGA 24360 TAAGGAATAG ACCCAGAGAG GCTGAGCAAC TGGGCCTATT CCACAGCTAC TATGGTGGAG 24420 ATGAGATTTA AATCTAATCA TTGGCTCCAG AGCCCATGCA CCCAATGGCT GCACTAAGTG 24480 AATGCATGCG CTATCAACGT TGCCAAAAGT GGGCCACAGC TCGGATCTGC GTTTTCCAGT 24540 AGCCAAAGCA GAGAGTGTGA TCAGACCTCA CTTTAATAAG CAAGTCTCAA GCCAGAGAGA 24600 GGTGGTATCA GGCAGCAAAC AGGCTGCTAG TCGAAATCCC ACTTCTTCTC TGAGTGGTCC 24660 ATACAGTTTT ACTCTACTTG CTTACAGAAT GAAAATAGCT GGAGTTCAGG TGCGCTTTCA 24720 ATGCCCTGTT GTCAGGATTG GGCTTTTCAA GTTTATTTTT TGTTGTTGTT TTTAATAGAC 24780 TGTACTTTTT AGAAAATTTT TAGATTTACA GAAAGATTGA GAGGATAGTA CAGAGAGTTC 24840 CCGTATACCT CACACCCAGT TTCTGCAATT ATTAACCTCT TACATTCATG CGGTACATTT 24900 GTTACAATTA ATGAGCCAGG GCCGGCCGGG CACAGTGGTT CAGGCCCCTA ATCCCAGCAC 24960 TTTGGGAGGC AGAGGCAAGC GAATCACTTG AGGTCAGGAG TTCGAGACTA GCCTGACCAA 25020 CATGGTAAAC CCTTTCTGTA CTAAAAATAC AAAAAATTAG CCAGGCATGG TGCTGGTTGC 25080 CTGTATTCCC AGATACTCAG GAGGCTGAGG CACAAGAATT GCTTGAACCA GGGAGGCGGA 25140 GGTTGCAGTA AGCCGAGATC GTGCCACTGC ACTCCAGCCT GGGCAACAGA GCGAGACTCC 25200 ATCAAAAAAA AAAAAAA A AAAAAGAAGG AAGGAAGGAA GGAAAATTAA TGAGCCAATA 25260 TTGAGACATT ATTATTACTA AAGTCCATGC TTTATGCAGA TTTTCTTAGT TTTTACCTGC 25320 TGTCATTTTT CAGTTCCAGG AATGCATTCA GGATGCCATA CCACATTTAG TTCTCATATC 25380 TGCTTAGGCT CCTCTTGGCT AGACTGAGTT TTAATCTACT TTCTGCAGAG CCTGAGAACT 25440 TTAGCATAAT TTCCTTGGAA ATTACAGCTC AATATTTTCA AGCACTTATA CAAACAGCCT 25500 AATGTTACGT TGGCCCATAA CAGTGTTTCA AGGTAATAAA CTTCTTTGTT TTCTGTGCCG 25560 ATTGAAAGAA CTGCTGCTTA GCCTCCTGCC AGATGATGAA CTGGGTACAC ACGAGCATTT 25620 TTCCAGGTAA AGCATATTTC GTGCGACTTC TTAAGCTGCA GCCTTATATG CAATAATTGT 25680 CCATTTACAA GACTTATGTT CGAATTTCAG GCACTCTGTT TTCACTAACC ATATCCTTCA 25740 ACTTTGATAA GTACTGCTTT AATCAACTCA GAAAATTTAA CTTGACTAAT TTTTTTTCAC 25800 CATCAGTTTT TTTTCTGTTG ACTCTTTCTC CTTTTTCTGT TTGCCCAGAA ACATGCTCAG 25860 GATTCTCTCA GGCTTTAAAA AATGAAAAAA TGTTTCCTGC AATCTAGTTA CTCCTTGATT 25920 CTCTTGTTCT GTTTATCGCT GGAATTCTTG AAAGCTTGGT GTATTAGTCT TTTTTCATGC 25980 TGCTGATAAA GATATACCTG AGACTGGATA ATTTATAAAG AAAAAGAGGT TTAATGGACT 26040 CACAGTTCCA CGTGGCTGAG GAAGCCTCAC AATCATGGTG GAAGGCAAAA GGCATGTCTT 26100 ACATGGCAGC AGACAAGAGA GAATGAGAAC CAAGGGATTT CCCCTTATAA AACCATCAGA 26160 TCTTGTGAGA CTTATTCACT ACCACAAGAA CAATATGGGG TAAACCGCCC CCATGATTCA 26220 ATTATCTCCC ACCGGGGCCC TCCCACAACA CGTGGGAATT ATGGGAGCTA CAATTCAAGA 26280 TGACATTTGG GTGGGGACAT GGCCAAACCA TATCACCTGG CCTATAGCAT TATTTCCATT 26340 TCTTCCCCAT CCTTTTATTC CTCAAACCGG TACAACCAGA CCTCTTTTTT TTTTTTTCTA 26400 CCTGAAACTG CTCTTTTGAG GGTAGCTGAT AAGTCCAAAA TACTGTCACC TTTTCTCAAT 26460 TCCGTTCCTT CTTATGCCTT TGGAGCAATT GACTGTGTTG GTTGCCCCCT CCTTTAAAGT 26520 GTCTCTCACT TGGTTTTATG ACTAATGATG ATTTTCTTTT TCCTCTCTAA ACATTCCGCT 26580 ATCTTTTTAG CTTCCCTTCC CCCTCCCATC CCCTAAATGT CCTTGTTTCC CAGAATCTGC 26640 CTCACCTCTT TGACTTCTCT ATGCCCTGTC ATTCACTCAT GGGTCTTTAT TACATTATTG 26700 CATCTGTGTC AATAACTCTG GTCTTTCTGT TAAGTTCCAG TCTCCCATTT TCAAATGTCC 26760 CCAGACATTT CCAATTGAGT ATCTCTCCAA TGTATTTAAC CTGCTAAATA TCTAACACAT 26820 AATCTTTCCC ATCAAATCGT TTCCTCTTAA GCTTTTCGTT ATTTCCTATT AGACTCCTGC 26880 ACTTCTCCCA GGAGCCCAGA CTTAAAACCT TGAATTTCTC ACCATAACCT CTCTTTTGTC 26940 TCCCATAATC AATTAGTAGC AAGTGTTATC AATGATTACT TGACAATATC TTTTTCTATT 27000 TCCCTCCCTG CTATGATCAT TCATCTAGCA AGAAGAGTTG GCCCTTTGTA TCTGTGGTTT 27060 CTGCATCCCT GGATTCAACC AACTGTAGAT GGAAAATATT TGAAGAAAAA AGCGTCTATA 27120 CTGAGTATGA AAAAATTTTA TTTCTTGTCA TTATTCCCTA AACAATACAG TATAACAACT 27180 ACAGCATTTA CACTGTAGCG TATAGATCTT ATAATCTAGA AATGATTTCA AGTACACCAT 27240 TATATATAAG GGACTTGAGC ATCTGTGAAG TTTGGTATTT GTGGGGCATA CTGGGACCAA 27300 TTCCCCCATG GATACAGAGG GACAACTATA TTTACTCAGT GCTTACTAAA TACCAGTTGG 27360 CCAATGTGTT TTTCTTTTTC TGTTTTCCTG TCTTTAGTTT GCCCCTTGCC AATTAATTCA 27420 ATAGTGCTGC CAATGCCAGG TGTACCTTCA GAATATTCTA TTCTAATTTT GTCATCTCCA 27480 AGCTTAAAA TATTTAATGG GCCAGGCGCA GTGGCTCACA CTTGTAATCC CAGCATTTTG 27540 GGAGGCCAAG GGGGGGTGTA TCACTTGAGG TCAGGAGTTC CAGACCAGCC TGGCCAACAT 27600 GGCGAAACCC TGTCTCTACA AAAAAGTATA AAAGTTAACC AGGTGCTGGA GCATTTGCCT 27660 GTGGTCCCAG CTACTCAGGA GGCTGAGGCA GGAAAATCAC TTTAATCTGG GAGGTGGAGT 27720 TTGCAGTGAG CCAAGATCTC TCCACTGCAC TCCAGCCTGG GTGACACAGC AAGACTCTAT 27780 CTCAAAACAA CAATAACAAC AACAACGAAA AACATTTAAT GGCTGCACCT TGCCTGTGAA 27840 AAATGCATTT CTTGGCCAGA TGTGGTGGCT CAAACCTGTA ATCCCAACAC TTTGGGAAGC 27900 TAAGGCCAGG AGTTCGAGAC GAGCTGGGAT ATATAGGAAG ACACAATCTC TACAAAAAAA 27960 AATCCACAAA ATTAGTCAGG CTTATTGTTC ATGCCTGTAG TCCCAGGTAC TCAGGAGGCT 28020 GAGGCAGGAT TCCTCAAGCC CAGGAGTTCA AGGCTTCCGT GAGCTATGAT GGCACAACTG 28080 CACTCCATCT TGGGTGACAG AGCAAGGTCC TATCTCTGGA GAAAAAAASA AAAAGAAGGC 28140 ATTTCTTAGG AGAGTTCTTC TCTGTAGAGT CCTAAGGGTT CCATGGAACT CCTTAAAAGC 28200 ATCAGAGTAT GTGAGTGCAA TGGGAGGAAG CATTTAGCCA GAGCAGTTGT GCTCCCATTG 28260 CATATTAATT TTTAAAAAAC AAAGCTATAA AAAAAAGTTG AAAACTACTA CGTTAGCATC 28320 AGCCTGACAT TTAATGGCCT CGTAAATCAA ACCTTAATTG ACTTTTTAGC CAGTTATGCT 28380 ACTAGCCAAC TACAGACAAC ACACTTTTTA ACCAAATTAG ACTAATAGTT GTCATCAGTG 28440 GAAATCAAGT TTGCCATTCT TCCATGCCTT TGCTCACACC ATTACCTTTT CTGGAATGTC 28500 CTGTACTCAT CTTCCTGTGT TGAACTCTAT ACCCAACTTT AAAAACCTAG CTCAAAGTTC 28560 AACACTTCCA TTCCATTTCA AAAAGAGCTT TCCTCTTCCT TAAAGTTTAA GAACTCATTT 28620 TCATGAATCT TTTTGGCATT TATTGCACAC ATGCTTGCTT TGTGTTATTT GTGTTCAGCC 28680 TCATATGCCC CCAAGGTGTT TTAGACTCCT TAACGGCAAA AATGATGCTC TAAACACCTT 28740 TCTATCTTTC ATAGTGTCTT AGTCTGTTTG TGTTGCTATA AAGGAATACC TGAGGCTGGG 28800 GAATTTATTT AAAAAAGAGG TTTATTTGGC TCACAGTTCT GCAGCTATAT AAGAAGCATA 28860 GTGTCAGCAT CTGCTTCAGG TGAGGGCTTC AGGAAGTTTC CACCCATGGT AGAAGGCAAA 28920 GGGGAGCAGG CATCACATAT CAAGAGAGGA GGAAAAAAAG GAAGGAAGAA AGGAGGGTGC 28980 CATTCTCTTT CAACAATCAG TTCTTGTGGG AACTAATGGG ACAAGAGGCT GGGCACGGTG 29040 GCTCATGCCT GTAATCCCAG CCCTTTGGGA GACCAAGGTG GGTGGATCAC CTGAAGTCAG 29100 AAGCCTGAGA CCAGCCTGGC CAATGTGGTG AAACTCCGTC TCTACTAAAA ATACAAAAAT 29160 TAGCTGGGCC TGGTGGCGTG TACCTGTAGT CCCAGATACT CAGGAGGCTG AGGTAGGATA 29220 ATCACTTGAA CCCGGAAGAC AGAGGTTGCA GTGAGCTTGT GCCACTGCAC TCCAGCCGGG 29280 GCAACAGAGT GAGACGGTCT CAAAAAATTT TAAAAACTTT AAAAATAATA GAGCAAGAAA 29340 GCACCAAGTT ATTCAGGAGG GATCCACCCC CAATGACTCA AATACCTCCC ACCAGGCCTC 29400 ACTTCCAACA CTGGGGATCA ATTTCCGTAT GAGATTTGGA GGAGACAAAT ATCCAAACTA 29460 TATCACATAG TAATGAACAT AGTACCTTAT CTATAGAAAG CAATGGCTAG ACAACTGTTG 29520 AATGGCTAAC CAAATCTGCT TTCCTATGGT CTCGCTCTAG AGGGGGTCAG TATGAGTTTC 29580 TGTCAAAAGG AGAAAAAARA ATGTATAGTC AGTTTTGTGT GTGTGTGTGT TCATGTAAAA 29640 GAGATCAAGA GAAAAGAACA AGAGAAATCA TGAAAAGGAG GGGGAATATA AGAATAATAC 29700 ATAGAAAAAA GCAAATTATC TTGTTTATCA GTAATACCCA AGGGGGTAGA AATGGTAAGT 29760 AATAATCCTT CTTCACTTTG TCTGTAGTTC ACTTTTTTGC ACCTTTATTT TGATGAATTC 29820 ACATCGAAGA CATTAACTCA TTAAGGCTTC CAATATTTTT GGAGATAAGA AGGGCTGCTA 29880 TGCTCTTTAT AGATGGAAAA CTTGGGTCAT TAATAACTCA AACAAGGACA TAACAAAGAA 29940 ATGGAGCATA AACTGCCAGG TCCTGACTGT AGATTTGGAT TCCCAGTTGG TGTCTTGTCA 30000 CCCTTTGTTA CTCTTCCTAA AGTTATGATC TTTTCTTGTG CATAGGAAAT TCATAGTGAT 30060 TTCCCATCAC CCTTGGGATT ATCATAGCTC CTTTAAGGTC CCCTCTATGC ACTCAATAAC 30120 ATCAACAGTA AGTGTTCTTC GAGCACTTAC TGAGTGTATA TCATTGTGTT CTCACGCAGC 30180 ACCCACAGAT CTCACCAAGA ACCTAGCTGA AGCCTGTAGA ATGAATAGGT AAGTACTGCC 30240 ATGCCAATCT GGAGTACTCA AGCGATGCAA ATGATTCCTT TAATTGTACT TTTGCAGGCT 30300 TGTCAGTTTT GCTCATGGAG AAGTGGCTAC TGCATCCATG TTATATCTAT GTAATGTTGG 30360 ACTGCGAAGC ATCACTTGAC TTTTTCCAAG CAGAAATTAC AGCTGATGAC AAGCTGCTGC 30420 TGAGAAAATG GATATTTTTC TGAATTCAGT TCTACGTGGA AACAGCTGAC TAGTTTCCAT 30480 TGCTGTAAGA ATGGCTCTTT TGCTCTTGGT TGATTTTGAG TAATGGCTTT ACTTCTGTAG 30540 AAAGGAGATT TCATTTGAAG TCCACTCAGG GATTTGGTTC AACAAACTGG AGTACAGGTT 30600 TCAGAAAATA TCTCTTTAAT CCTCCAATAA TAAATTTTCT CATCTATAAT TCCTGGAACA 30660 CTTCATCCTT TGCAGCCGAG CATATAGATA GATTTGTTGC TCACTGTGTT CTGATTGCCA 30720 CTTTGACCTG CTTTTTCAAC TTAGGTTACA AATAGAACAG AATCTCTCTG ATTTTTCTCA 30780 TTAATTGTTT GAATTCCCAC TTTTCCTCAT TAGCAAGAAG TCCAGTATCT TCCTGAGAAC 30840 TTCCTTTTCT CAATCTAGGA ACTTACTTGG TCCATAAGGT AACAGTCTTA TTTCTGACTA 30900 TCAAGGAGAG AAATAACAGG AGCCATTATC ATCTTCATGG TGTCACTTTT GAAAACTGGT 30960 CCTCTGTAGA TCTTCAGATT CTTGCGTTAG TCCATTCAGC TGCTATAACA AAATTGCATA 31020 GACAGCATGG CTTATAAATA ACAGAAATGT ATTTCTGACA GTTCTGAAGG CTAGAAAGTC 31080 AAAGATTAAG ACACTGGCTG ATTTGGTGTC TGGCGAAGGC CCATTTGCTC ATAGATGGAC 31140 GATGACCTTT CACTCTGTCT GCACATGGCA GAAGGGCAAG AGAGCTCTCT GGGTCTTTTT 31200 TATAAGGGCA CTAATCTCAT TTTTGAGGAC CCTGCCCCCA TGACTTAATC ACCTCCCAAA 31260 GGCACTGTCT CCCAATACCA TCACCTTGAG GGTTAGGATT TCAACATATG ATTTTGGGGG 31320 GACAGAAACA CGCAGTCCAT CTCGCTTGTC CACTCCATGG TGGTATTCTT GCTGGATCAG 31380 TTTCCTCCTT GGGGTGCATT TGTGTTCCAT GTCTAACTTG CAAGTTATAG CAGGCCCGAT 31440 AGCAAAGTAT TCCAATGTTG GTATGCAGAG GCATTGAATA ATCAGAATGA ACCCACGCCA 31500 TAAACAACTG GTAGAGCTGC AGAGAGTACC AGCTGATTAT GAGCCCTGGG TAACAGTGGT 31560 TTTTAGTTCC TATGTCCGTC AGCCCTTTTC TCCCATAGTA GCCCCACTGT GTTGAAGTGG 31620 CTGAATCGAC AGAAGCTTCC AGCTTGGGCC ACATGCTCAT GGAACCAATT CTCCTTATGA 31680 GCCGTACAAG AGCTGGGTTG CCATTCTGGA TACCCTCTTT TTTCAAGAGA TTTTATTTCA 31740 AGGATATTTT TTCTTTTATC AACTACAGGG ATTATTTAGA ATCTTAGGGC AGTGGTGCCC 31800 AACCTTTTTG GCCCCAGGGA CAGGTTTTGT GGGAGACAGT TTTTCCATGG ACCAGTGTCA 31860 GGGGGCTGGG AGGCATGGTT TTGGGATGAG TCAAGTACAT TACGTTTGTT GTATACTTTA 31920 TTTCTATTAT TATTATATTG TAATATATAA TGAAATAATT ACACAACTCA CCATAATGTA 31980 GGAATCAGTG GGGAGCCCTA AGTTTGTTTT CCTGCAACTA GACAGTCCCA TCTGGGGGCA 32040 ATGGGAGATA GTGACAGATC ATCAAGCATT AGATTCTCAT AAGGAGTGCT CAGCCTAGAT 32100 CCCCGGCATG TGCAGTTCAC AATAGGATTT GCTCACCTAT GAGAATCTAA TGCCACTGCT 32160 GATCTGACAG GAGGTGGAGC TCGGGCAGTA ATGCGAGGGT TGGGGAGCAG CTGTCAATAT 32220 AGATGAAGCT TTGCTCGCTC GCCTGCCACT CACCTCCTGC TGTGTGGTCC ACTTCCTAAC 32280 AGGTCACAGA CTGGTACTGG TCCATGGCCA GGGAGTTGGG GACCCTGTCT TAGGGAGTAG 32340 GGGTGGAGTT CCCTTCACTT CTAGAAGGCC CTGGATTAGT ATCCCAGAGC TGTCATTACA 32400 GAGTATCACA AACCAGGTGG CTAAAAACAG ACATGAATTC TCTCTTATTT TTGATGGCTT 32460 GGAAGTCCAA AGTCAAGGTG CTGCCAGGGC CATGCTCCCT CTGAAATGTG TAGGGGAGAA 32520 TCCTTCCTTC CTCTTTCTAG CTTCTGGTGG TTTGCTGGCA ATCACTGGCA TCGCTTGGCT 32580 TGCAGCACTT CAACATCTGC CTTTACTGTC TCATAGTGTT CTCCCCTCAT GTCTCCAGGT 32640 CTCTCTGTCT CTCTTCTTTG TATAAGGAAA CTAGTCATAT TGGATTAAGG GCCAACCCTA 32700 CTCTAGTATG ACCTCATCTT AAGGTCACAT GCAATGACTA TTCCAGATAA GGTCACATTC 32760 TGAAGAACTG GGAGTTAGGA CTTCATATCT TTTGAAGGAA CACAGTTCAA CCAATAACAG 32820 CCCCTGTACT GTTTTACAAA TAGGTATTCC TCTCCTTCCC AAAGTTCTTC ATAGCAGAGA 32880 CAACTTGTAC CAAAAGGCAA AATACCTTAT TATGTAACCT TAACCTAGGA TCATAGATCC 32940 CTACTGTCTG GTGCTTTATA AGCACAGAAC CACCGGGAAA TCATTATTAA GACAAGGAAA 33000 GGCCAAGTGC AGTGGCTCAT GCCTGTAATC CCAGCACTTT GGGAAATTGA GGCGAGTGGA 33060 TCAACCTGAA GTCAAGAGTT TGAGACCAAA CTGACCAGCA TGACAGAACC CCATCTCTAC 33120 TAAAAATACA AAAATTAGTT GGGCATGGTG GCATGTGCCT GTAATCCCAG CTACTCAAAA 33180 GACTGAGGCA GGAAAATCAC TTGAACCGAG GATGCCAAGA TAGCAGTGAG CCAATATCGT 33240 GCCACTGCAC TCCAGTCTGG ATGATAGAGC AAGATCCTGT CTCAAAAAAT TAATAAATAA 33300 ATAAAAAGAC AAGGAAAGCC TTTTCCAAGG AGACCCTTCT GCTTTGCTAG TTCAGAGAAC 33360 TTCTCTTTTG GAGAAAACAA ACACCCAGTC CATTAGCAGC AACGTCAGGG ATTGAATTCT 33420 TAGGGCAGCA GGCTGGGCAC AGTGGCTCAT GCCTGTAATC CCAGTACTTT GGGAGGCTGA 33480 GATGGGTGGA TCACTTGACA TCAGGTGTTC GAGACCAGCC TGGCCAACAT GGTGAAAACT 33540 <BR> <BR> <BR> <BR> <BR> <BR> CATCTCTACA AAAAATATGA AAAAAAAA A AAAAAAA AA GCTGGGTGTG TTGGCTTATG 33600 CCTGTAGTCT CAGCTACCTG GGAGGCTGAA GCAGGAGAAT CACTTGAACC CGGGAGTTGG 33660 AGGTTGCAGT GAGCTGAGAT TGCCCTACTG TACTCCAACC TGGGTGACAG AGAGAGACTC 33720 CATCTCAAAA AAATAAAGAA TTCTTCGGGC AGCAGTCTTT CCTCCACCTC ATAGACCATG 33780 GAGGTGAGCC AGCTCTGACA AACCATGAGA ACAATGGCAG AGACATACCT GTAACGTAAC 33840 TGACTGGGGC AAAGACAAAG GTGAGGAAAA TGACAAGTTT GAGGAACTAT GAGACCAGGC 33900 AGTGGGGAAC ACCACTAGCA GAAATGATGG AAGTTCTCAA GAATAACAAC AGAGAAATAG 33960 ACCATGGCCA GAGTCTAGAA CCCTCCAGGG AAAGGAGATG GGCTCCAGAG GCAGAAGAGG 34020 ACGTTGAAGG GAATGGGGAG TGGGTGAAAT ATATAGACGA TGGGGACCAC CCAAGAGCAG 34080 TCGCTATTGC AAAACTGAGG AGAAGGAGAG TCTGGAGGGG GTGGTGGGAA GCTGGGTCTC 34140 CTAAGGAGGT TTTGACAAAA GCAGTCATGG AGCGGGCTTA GAAATCACAG TTGGGGACAG 34200 GGTAAAGTTC CTCGGGATAT AGAGGATGAG ATTAGAAGAG GTTCCAACTA GGGTAGTGTG 34260 GAGAAAAGCA CTATTGACCC AAAAAGGAAG GAGAATGTGG GTGGAAGTGG CAGAGAAAGA 34320 GGGGTTTGAG CAGAGAGTGG TGATTTTTCT AATGCAGAGT TGTGGGAGGT GGAGTGCAGG 34380 GAGCCAGGCT GGGTGGCTGT GCTGATGTGA TTAAGCACTT ACTGACTGCC AGGCAATGGG 34440 CTAAGTACCT GAGATGCTTT GTCTGTTATC CCTCCCGAAA CCCCTCTGAG CAGGTGCAGT 34500 TATTATTCTC ACTTCACAGA TAAGGAAATT GAGGCACAGA GAATTGAGTA ACTTACCCAA 34560 GGTGACATAG CTCATATATG GTAAAGCAGG CTTTGAACTC AGTCTAGCTC CCGAACCTAA 34620 GCTTGTAACT ACTATGCTTT TCCCAAAAAA AGGGGGCTGG CACAAAAAGA GCTGAGGGGG 34680 CTGGGCATGG TGGCTCATGC CTGTAATCCC AGCACTTCGG GAGACTGAGG CAGGTGGTTC 34740 ACCAGAGTTC AGGAGTTCGA GACCAGCCTG GTCAACATGG TGAAGCCCTG TCTCTACTAA 34800 AAATACAAAA ATTAGCTGGG TGTGGTGGTG TGCACCTGTA GTCCCAGCTA CTTTGGGAGG 34860 CTGAGGCAGG AGAATCGCTT GAACCCCAGA GGCGGATGTT GTAGTGAGCC AAGATCATGC 34920 CACTGGACTC CAGCCTGGGT GACAGAGTGA GACTCCATCC AAAAAAAAGA AGAGCTGAGG 34980 TGATGGCCAC CATCAGCATC AGCCTGGAAG TTATAGCAGG ATGCTAAGTT TCTCTAAAGC 35040 TGTCTTTCTT AGGACTTGAA AAAGATAACT TGGGTTTGTA TCCCATCTCT GCCATTAGTA 35100 GTTTACTGGC TTTGGATAAA TTACTTAGCC TTACTGAACC AACTTTGGAT TTTTATAGAG 35160 ATACTGTAAT GAAAGGAATA AGGTATCAGT CTTAGCAGAG CATCCAGAGT GTTCCTATTA 35220 AAACCTAAAT CATATCCTGT CATTGCTGTG CCCCAAACCA TTCAATGGCT TCCCAACTCA 35280 AAGTTAAAAA CTCATCTTTC CAGTGGCCTG CAAGAGCCTA TGCTATCCGG TGTCTGACCT 35340 CATCTGTTGT TCCTTTCTCC CTCCCTTTCT TGGCTCCAGA CGCACTCTGG TCTCCTTGCT 35400 GTTCCTTGAA TACACCAGGC ACACTCTCTT CGCCTGAAAC ACTTTACCCC AGATATCTTA 35460 GCTTACTCTC TGCCTCCCTC AATTCATTGA TGAAATGTCT CAGTGAAGTC TTCTCTCTCT 35520 CCTCTGTAAA AGTATACTCT CTGTTCCCCT TCTTTACTGT TCTAGCTACT ATTGCTGTGT 35580 AACAAATCAC TCCCCAAATT TAATGAGTGA AAACATCAGC CATCATCTTA TTTCTCACGG 35640 TTTCTGAGGG TCAGGAATTC TGGAAGGGCT CAGCTGGGAG GTTCTGGCTC TATAATCTCT 35700 TATGCAGTGA GAGTCAGATG CTGGCTAAAA CTGAAACAAA GCAGGGTTCT AGTAGCTGAG 35760 GGCTGGCTGG GTCTCTCAGA TATAGTTCAG ATCTCCTCCA GGGGGTCTCT CCACGTGGGC 35820 TAGTCTGAAC TTCCTCACAG CATGGTGGCC TCAGGGCAGT GGACTCTGCA TAGTGGCTGA 35880 AGGCTTCGCA GCTGAGTATT CCAGCAAGCA AAGTGGGAGC TGTATTGCCT CATATGACCC 35940 AACCTTGGAA TCCACACAGC ATCACTTCCG TGTATTCTAC GGGTTGAAAA GTCACAAAAA 36000 CCAACCAGTT TCAAGGAGAA GGAACAGAGA TCACATTTCT CAATTGGAGA AGGGTCAAAG 36060 TCACATTGTA ATCAGAGCCT ATGGGATACG AAGTATTGCG GTCAGGTATG AAAAATTTGA 36120 TTTGCTGCAT CTGCTTTACT TTCTCCACAG CGTTCATGAT CTGCTTCTCA CATGATATTG 36180 ACTTACGTCA TTTCTGCGTT TCCTGTCTTC CACACTAAAA TGTCAGCCTG TTTTGTTCAC 36240 TGCTGTATCC CCAGAGCCTA GCACGGAGCC CAGCATGTAG TGGTATCCAA TAAATACTTG 36300 TTGCATGAAT GAATTCTGTC TTTTAATCCT AGCTATAGGT TTCTAAGTTA AATATTACTA 36360 TAATCATCTT ACAGACGAGG GAAATGAGGC TCAAGAAGAT TTGGTAACTT ATGCGGGATC 36420 ACTCAGCCAC ATAATGGAAG AGACAGCATT GAAGTACACA TGCTTGCTCT GTCTGCTCTT 36480 CCAAGCTGCT CATCACACAG CTGCACCTCT GAGGACTTCC CTCCCCAGTC CACCTCCACC 36540 CTTACCCAGA GACACACATG GCCACAATCC ACTAGCAGAC CAAAATTCAA TTTTTCCCCA 36600 GTTGGTTGCA CTCAAGCTGA GAGCAAAGCA ATTGCACTTT AAATCCCCTT ACAGCAGATA 36660 TTTCAGAGCA TGTTCGGAAG AACCCATCAC ACTTGGCTTT TAGATCTTAT TTCTGGTTTG 36720 TTACAAAAAC ACAATTAAAT GAAAGGTTAG GTAGCTTTTG AATGGCCAGC TCAAAGTTTT 36780 GGCTTATTTT TGCCTTGCTG TCTTTATAGG CATTTTACCA ATATTTATCA CTATTTCCCT 36840 TAGGGAACCC TTAGATCTGT GATATTTGAA ATAATAAAGC CTCTCCATTG GCCCTTTAAA 36900 AGGTTTGTGG TAAAACCACA CCATTAACAT TCACAGTTCC TTATTTATGA GGCCTGATTG 36960 CACTTATTTC CATATTTCTC ACTGTTTCTC CGATGAGGAT TTCACATAAT AGTGTTTGAA 37020 GGCTAAAGAC TTCAAAGCAG ATTCTTTACT ATTTTTATCT TGAAAAATAT TCAATATTTG 37080 TGTAATTAAA GTGAAGTCTT CCTAGAGAAA ATGACAACTC AAATAATCTT AAATGTACCT 37140 CCAAGAAAAA AGCTGTCAAA GTGACATTTA GTAATAGAGT CACATTCTCT AAGGCCTTTG 37200 CTTCTCCTTC TGATTCTTAT CATCTTTGAA GGTTATGTCA TGGGCTGACT TCAAATCAAC 37260 TTTTAAAATT ATTATGGCCT TCTTTAAATG TGAGTTCTGA AGGTGAGGGG CTTTATCTTT 37320 CTTTTGCTCC AGATTTTTTT TACCGCGTCA TTACCAAGCA TCTTAAAACA AAACCTAAAA 37380 ACAAAAATCT TCCTTGACCT GGTTTTTCCC ACTAGCTAAC ATCCTATTTT TATCTTTCCC 37440 CTTTGCACTA AAGGTTTTTA AACGGATCTT TATACCCTCT GTCTCCATTT TCTCATCTGC 37500 TAACTTATAT GGCAAAGATT ACCACTGCCT TTCAACATAA TTGGCCAATC TACAGAAAGT 37560 TTTCAAGTTC TCTTTTTAAT TGACCACCTC CTGCCTACCT CCCCACCTTT GACATCTTGC 37620 TTCTCACTTG GCACCTTACC CAGTGTTCAA GATTCCCTCC TTTAGGATGT CTTCAGAGCA 37680 GCTACACAGT TGGTACTATA ATTTATACAT CCTTGTACAC AGGGCTTGCT GGGATATTGA 37740 TGGAGAGAAG GAGGAAACTG GAAGTAGTTC AGGCCAGAGC TAGGGAAATT GACCCATCTC 37800 CAGGTCTCAG GTCTGCAAGG GGAGCTCACA GCTTAACACA TGGAGTCTAG AAACTTGTGC 37860 TGGACCTTGA CCAACACCAG CCCATGGAGT CCAATACAGT GCTCAATAGG GATTTCCAGG 37920 AAATTGCTAT ATTTATTCAA AGAGAACTTA CCAAGTGTCA GCTACGTGTT GGGCATTGTG 37980 CTAGGCACAG GGACCACAAA GATAAGACAT TGTAGCTTTC CTTAAGTTGC TCACTGAGTA 38040 AATAGAGAGA CAGAAAGGTA AACAGGTAAG TGCAAAAATA CATACAATTC AGCAATAGTG 38100 TTCATAGTGG CTATGGAGAG AACGCTCACT AACTTTGTTT AAACAGTTGT TCTTTCAAGG 38160 ATTTGACATG GATTTGATTG GAAAAGCATG ATACCATTTT TTGCAATTAA ACACAGGAAT 38220 ACATAAATAA AATGCATCAG TATTTTTTAC AAATAGCTAC TAAGAGCTAC TAGAAAACCT 38280 GGGAATTCTT AAAACCTTAC CATGCTACTT GCTCTAAAAT ATTTTATTTT ATGTTATTTT 38340 GTACATTTCT TTACCTACAC AAACACCACT GTTTTCTTCA TTTCTTAGTC TATTTAAACC 38400 TCACACCCTT TCAGCATCTC TTAATTATTT ACTACCATCT GTTAGTTCTC CTGTCCTGAA 38460 TGAAACAAAA ATGGCAGAAT GTAAAACGAG GGCGAACAGA TTTTTGACAG GAAGTATTCA 38520 GAGGTAGAAG GAAATAGTCA AGACACATAT GATAAACGAA AACAATAATA ACTTTATACA 38580 TAACAACTTA TAGACACATT TAAAAAGTTT AAGATCTCAA GAGCTATGTC TGAATAGATA 38640 GGAGTAAAAA CTCTATTAAG TAATTAGGAA AATAACAAGA ACAGTGAATT TCTTAATGAA 38700 TGGCATGTAA TCAAAACTGT ACTTATCGTC TAATTCATAA TCTTGAATGT TTTTATTTTA 38760 TTTATTTATT TTTTTATTTT TTGAGACAGA GTCTTGCTCT GTCACCCAGG CTAGAGTACA 38820 GTGGCGTGAT CTCAGCTCAC TGCAACCTCC ACCTCCCAGG TTCAAGCGAT TCTGCTGCCT 38880 CAGCCTCCTG AGTAGCTGGG ATTACAGAGG CCTGCCACTG CACCCGGCTA ATTTCTGTAT 38940 TTTTAGTAGA GATGGGGTTT CACCATCTTG GCCAGGCTGG TCTTGAACTC CTGACCTCAT 39000 GATCCACCAG CCTTGGCCTC CCAAAGTGCT GGGATTACAG GCGTGAGCCA CCACGCCTGG 39060 TCGAATGTCT TTATTATTTG AAGAGACAAC ATGGGCCTTA AATCTGTCTT CTATTTGACA 39120 GACTTTGATG GAGTCAAATC CCAATGCTGC CACTTACTGA ACGGCCTTAA ATGACTTAGT 39180 CTCTCTCAGC TGTCTTTCTG CATATGTAAG GTGGAATAAT GATGGCTTTC AAGGAGGAAT 39240 AAACCTATGA AAAGTGTTGA GGATAGTGTT TGATATGAAA TAAGGATTTC AACAAGTAGT 39300 AGCTGCTATT GAAGATTTAA GAGTTATTTA TTACAACTAT TTAATAAAAT TTTAAAAACT 39360 AATACACTTA AATTATTAAA GAGCTTTGAA ATGGGCCAGG CGCAGTAGCT CCTGCCTGTA 39420 ATCCCAACAC TTTGGGAGGC CAAGGTGGGC GGATCACCTG AGGTCAGGAG TTTAAGACCA 39480 GCCTGGCCAA CATGGTGAAA CCCTGTCTCT ACTAAAAACG CAAAAATTAG CCAGGTGTGG 39540 TGGCATGCAC CTGTAGTCCC AACTACTCAG GAGGTTGAGG GAGGAGAATT GCTTGAACCT 39600 AGGAGGTGGA GGTTGCAGTA ACCCGAGATG TCACTGCACT CCAGCCTGGC AACAGAGCAA 39660 GACTCCATAA AGACAACAAA AGCTTTGAAA TTGTGTAAAT GAGTTGTACC TATCTTCATT 39720 TAAGAAATTC ATCTTTGTTC ATTTATTTTT ACTTGACATG AGAGCTTCCA GCAATTTTTA 39780 ATTAAGCCCT CACAGATTTT ATGTCACTGG CTATGTGATA AACAAATTAT TTGCTAAAAT 39840 AATATTCTTG CTTCTTTTTT AAGGAATTGT CTCCCTAGAA ACGGTTTGTA CCAAACAATA 39900 CACTGACTTT ACACAAAATC AGATCTGATT GGCAACAGTT GCAGATGTTT TCAAAAGATT 39960 TTCATTTGAG AAGGGGCCCA TTTGGGTTAT TTAGATTCTA AGAACTGAAA CTGCTTTGTT 40020 CTGTTTTTCT GGCTTCTGGG AGAGGAGGAG ACATGAATTC AGTTAGCACC TTGGTATTTT 40080 CTTTATCCTT CATTTCAATA CAGAAGATGC TTCATATGCA CAGTGGTGTC AGGTCACATC 40140 AAAAGAAAGA GAAACAGTTT CTTGGTTTTT AATTTTCAAC CGGAAAGGAA AGGCACCCAT 40200 TTTGTTCCGC TCTAATTAGC CAGTGCATGA CTTAGAGAGC AGGCAGATGC TTTGAAGGCG 40260 TGGTAACACA GGTCTTCATT AATCTCCACG CAGGACTTGC ACTTCTACTA TGCCTAGGCT 40320 GAAGAAAATG GCTCAGGAAG ATGAACAATC TCACAGAGCC CTAACTAACT GAAGCCAGGT 40380 GTTATAAAGC ACAAGTCAAG AGGGTGAGAA ACTAACGTTC TTGAAATCTC CCACTTCTTT 40440 CTACGTCAGA AGAGCCAAGC TGATTATTTT AGTTGGAATT TAGAAATTTT TAAAAATTAT 40500 TCTAAAGTCA TGAACAAGCC TAATTATAAA GATAGTTGCT GTGAAGGTGC TGAAATAACT 40560 CGATTTTACC AACCCCCTCT TCTGGAGGAA GCCATAATGG AATCCTGTAC AATGTTCACT 40620 CTACCAACGA ACTCTTGTTT TTCTAATGAG GAAACAGAGG CCCACAGTAT TAAACTATCT 40680 TAACCAATAC AAAATGACTA GTGCTCTGGT CCTTTTATTA AGCACTAAAA TTTTGATCCA 40740 ATAATAAATC TGTCCATTAG AAGGAGTTTC CCTAATGTAC TGGTTCTAAC TTGTTCCCTT 40800 CAAGGGGCCA GTGTCCCGTA CACATAGCTA AATGGGACTT CTCTTCAACT ACCATTACCC 40860 AGAGGGCAGA ACCTAAAATG CTGTGAATGA CATTCTGCTG TTCACATCTC AGCAGCA 40917 (2) INFORMATION FOR SEQ ID NO:3b: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 39678 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:3b: GTGTTGCATT TGAGCTTCTG CAGGGCCACC CAGGACCTAT ATCTGCTCAG ATGTTTAACT 60 CATCTAATTC AGTGAACACT TCATTCTAGT TAACTGAACA TCTACTTTGT ACAAGGCACT 120 ACAGCGGTTC AGAGATGAAT AAAATCATGA GATTCCACTG TCTCCTATAA ACCATCACTT 180 TGGGAAATTT TAGAAATGTG GGTAAGCTCC AGGGCTTCCT GCAGCGTAGA AGTCACAAAC 240 TCAAATGCCT GCAGAGGCCC AGCTGACAAC ATAAGTAAAT GATTCTGGCT GGGCGGAAAA 300 CAATTACGGG TGGGTGGGTT TCCAGCTGGG GAGTGCACGC CTGTGTTAAA GGACAGCTGC 360 TACTCATTTC CAGCCAACTG TGTTCCCATG TAGAACTGCG GCCCAGTGTA GCCAGTACCG 420 AAGATTTCTC AGAAAAAGCC GGAGATCTCA ATGTTAGTGT AAAATCTCTC AAATTTCCAA 480 GAGGATTATA TGGGGCAAAG GTTCTCAGAT CAGTTTGCAG TCTCTTACTT AGCCCATGTG 540 CAGAGCAGTC GTAGAGGGTA GCATGCAGTG TCCTACATAA TAATTCTTTT TTATTTTATT 600 TTATGCCTTC CTCCTTCCTG TCTCTCTTTA ACCTTTCTTC TTCCCTCAGG CTGGCTTCTT 660 CCCTCAGCCT CGTCCGACCC CAGCCTGGGT TCAATGAACA TTCGGTAAAG GAACACGGAA 720 TGTCAAGCGC ATTAGAGACA ACCTTGAGAC ACATTCCTCT TGCGGTAAGC ACTTCACTGT 780 AGATTTTTAA TTTTAAACAA GACAATGTTT ACGACTTGCT TCTTTCAGGG AAGAGCGATA 840 TCAATTTTAG TGAACACTTC AAGGCTGAGA TACGCTAGGA GAGTCGTGTG GTGTTGCACA 900 GCAAAGAATT CCACTTTGAA GCGAGTGGGA AAAAAAGCAT CAAATGCCAC ATGTAACTCA 960 CCGCCTGAAG GGTTACATTG GTATGAAACC TGGGTTTAAA AAGGGACCGA ATAGACTAGC 1020 CATTAAAAGA CCTGCGTACA ACCTCTCTCT CTCTCTTTGA GAGATAATGT ATCTGGACAA 1080 TAAACATGAA CAGAGTGGAG TCTATCCTGT TTAAAACATT GCCTACTGTA CAGGCACCAG 1140 GAGCTGAAGG GTCAGAATAT TAGCAGTGGG AGCTTGATTA GAGTTGATGA GAGATGGGTA 1200 GTAGGAGGAA AGAGTGAGAT AGAGGAAGAG GACATGGGGG TTACCCATAA GTGGAGAGTA 1260 GAAAAGTAGA ATCAGCTGGC CATCAAAGGG CGTGGGACTG AGGAACAGTA TGGCATGTAT 1320 TAAATATACT AAGCGCTGAC ATTGGAGGAG AACTAGGAAG TTAAATGAAA TCAATAGGGG 1380 ATGATGGAGA ATAGTTAGGT GTGCAGGGAT TAGGGTTATG ATAGAAATAC ATGTGAATAC 1440 ATGCAGTATT GTCCTGGAAA ATGGTTAACA GTTGGTTCTC CTGGGGGGTG AGGGGAAGCC 1500 CTGATTTGTA ATATTTGCCT ATTTCTGTGG TGCAAATACT CCCACCATGA CCAGTTTCAA 1560 GCTATGAATG TTGAAGTCAC AGAAAGCAGG TTGGGAGGAG ATGCGCACAT TTGTTCCCCG 1620 GCAAGGTGGA AGGTAAGGAA GGTGAAATCA ACAAGGTCAA AGAAAACTCA AGATTTCGAG 1680 GTGCCTCAGG TCTGAGGGGC AATGAAGTCT AGGAATGGCT GTGCTGAGGT AGCTGAAATA 1740 GAAGTGACTG CAGAGGTCAT GAAGCTGAAG AGGTGAAAAC AGAAATTAGA AAGGCAAACC 1800 CCCACCGCCC AACCCCCACC CCTGCAGCCA GTTTCTGAGG GTGACAATAG AGGAAAGGGT 1860 GGAGATGGAG TTCAGGTCCA GAAGCCATAG AAGCGAGTGT GACATTGTGC TCAAGGTCAG 1920 CACATGTCAG TGTGGGGTGT CACATGCTGT TGTGAACCAT CATTTATCAC CAATTATGGA 1980 AGACCTCCTA TGGGCATCTT GCCATATGCA TTATAAAGAT GTGTAAGAAG ACATTTCCCT 2040 CCACTTGGTG AGGAGAATTA GGGCTGTACA CAGATACTGT AGAGTGCCAT GTGCCTGGTA 2100 CAGATAAGGT GTGTTAGAGG TTAAAAGATG AGGCTCTTAA TATTAATGAT AGATCCCACT 2160 TACCTGAGTC TGACTTACAA TGTGCCTAGC ATTAAGTGTT TTACCTGCAT TCCCTTTGAC 2220 GTTCAGAACA ACCCATTTTA CAGATAGGGA AATTGGGTCA GAAAGTTTCA GTAACTTATC 2280 CAAGGTCAAC ACAATTGGCA AGTGCCAGAG CTGAGCCAGG AACTGAGGTC CTTCTAACAC 2340 CAAACAGCTT GTCTCCCCAA TCACTGTGCT ATTTTCCTCC CCCAGAAGAT AATACTCTGA 2400 TGGAAATGAA GGATAGTGTA ATAGGAGATT CGGTGTTCCT TTTTTTAAAA AAAATTCAGC 2460 TTGCATATTC CTAAAGAGTC AATTCATGTT TAAAAAAAAT TTCCCTTGTG CTTGCATGTG 2520 ACATGTATTT TTAGGATCTG CTGTTAGCAA GTGTATTTTT GTGTGATTGA GTGGGAGAGT 2580 GGGAAAAGTT TTGCAGAGCT GTTGAAGCCA GAATGCAGGG GGGCTGCGCA GCAGAGACTG 2640 TAAAATCTCT GCCATCTCAG GTCTTGGAAC AAGCACAAAG AGATGTGTTC TCGATTTATT 2700 ATTCTATGTA CATCCCCAGA TGAATGACTA GTTAAAGGTA TTGTTAAAGC ATTTTAAATG 2760 ACCCACTTCC AGCAGCGAAC AAAATCACTT GCTGTGCCAA GCCAACTGGC ATTTCTGAGA 2820 TGATAAAACC ACAAAGTGAG GAAAACGTTA AAACTGCTAA AGCAAAAATG ATACACAATA 2880 ATGGAGAAGG AGAAAAATTG AGCTTTATTG TCTGCCTAGG CAGATGGCTG ACCACTAGGT 2940 GGGCCTCGGC GTCACGTCCA GGGTAATTGG TTGCTGGGGT GTTTCTGGCG AGGAAGATTC 3000 ACGCTTCAGC TCGGTCCACA AGATCCTGGC TCATTCTTTC CTAGATTCCA TTTTCTGCCT 3060 CCTCTCCATG ACTGGGTCTG ATGGTTGATC CAAACGGGCA ATTGAAATCA GAAGGTTACC 3120 TTTACCTTAA AATGCTTTTC TGGAAATAAA AGGACATGAA AAGTAACTAA GGACCGGATT 3180 TCCTAGCCGT CTTTCTCTCC TGCATGCGCA ATTTATCCCC AGATATAAAA TTGCCTGCTT 3240 TGATAATTAT ACCCTCTAAA TGAGGGGCAA GTGGCTAATT ATGCCCACAT GTGGCCGATT 3300 GCACTCCCCA TTAGCCAATT ATGTGCTCAA TTATTTGTGC ACATGAATAA TTGCACTCAT 3360 GGAAAATAGC GCCCTCCTTT CAAATCCTCG TGCTTGGAGT GGCTGATGGA GTAATTGTCA 3420 CACTGGAAAT GCACTTGGTG GGGAGGGAAA GAGTATCAGA TACCAGGAAA CGCATAAGTG 3480 ACCAGAGCTC GCAGATGTTC ACTGCCACAA ATGGCCTTAG GAGCCAGAGA GAGCGGGAAG 3540 GACCACAGGA TGGAACGGGC CAGCCTGTGA GTTAGGAAGC CTGCTTCTGA AGTTGCCTGG 3600 GCAGCTCATG TGCGGTGACC TTGGGCAAGT CATTAACTTT CCTTCAGGTC TAACTGGTTC 3660 TGCATACACA ATGAGGATGG TAATAACGCC CAATTCCCAT CACTATCGTG GGATGGATCA 3720 GACTATTTAA AAGGATTTAC AATCTGCTTG GGTAAAAGCT TTACATAAAT ATGAGGCATT 3780 ATCATGTCGC TTGGTACATC TCCAATTATG AAGGAAGGGT AATGACCCTC CACAGCAATG 3840 CAGGACTCCT GGTTTGGAGG GAGGGAAAGT TTGAGAAGGA CAGGAAGCTT GTTGCCCCAG 3900 CACTGATGTT TCTACTGAGG TACCAGAAAA TGTCATGTGG TCATACAGAA TTCATTTATT 3960 CATTCAACAA ACATCTGTCA ATTGTTACAC TGTCCTGAGA ATTTGGAAAA ATGATGAAAG 4020 ACTCAGTCCT GCCTTAGGAG GTCACTGGCA CATTGGCCCG GGCCCCTGTT TTGGGCCTTT 4080 TACTCTGACC TGTGCTGATT TGCAAATAGT GGGAAATTTT ATCTCAAGTC TATGAAATCT 4140 GGCATGCATT TTCACGGTTT GATTGCCAGG TACATTCGAT GGCAATGAGT CTTATAATGT 4200 TTGGTTACCT TCATTTACCT AAGAACTGTG GTTGTTGCTG TGGTTGTTGT TTTTGTTGTT 4260 TTTGAGACGG AGTCTTGCTC TGTCATCCAG GCTGGAGTGC AGTGGCATGA TCTCCGGTCA 4320 CTGCAAACTC CACCTCCCAG GTTCAAGCGA TTCTCATGCC TCAGCCCCCT CAGTAGCTGG 4380 ATTACAGGCG CGCACCACCA TGCCCGGCTA ATTTTTGTAT TTTTTGTTCG GGACACAGAT 4440 TTCACATGTT GGCCAGGCTG GTCTCGAACT CCTGATCTCT GGTGATCCGC CTGCCTCGGC 4500 CTCCCAAAGT GCTGTGATTA CAGGCGTGAG CCACTGTGCC CAGCCAGAAC TGTGGTTTTA 4560 ATGACAATGC TAAAAAGTGG TATATGTCAC AGTGTCGGGT GGGGCTAAGA GGCACATTGC 4620 TGCAGTGATC CATCATTCAT TTCCCACCAT TCTCGCCTGG ATTAGCGCAG CAGCTCCCAG 4680 AGAGGCACCT CACTTTGACC TTCTTCCTCA AAGACATTCT CTGTGACCTG CCTGGCCCTT 4740 ATTACCTCTC TAGCTTTGCC ACTTCCCTAT GTCTCCATCT CCCCTCTCAC ACGTAGTAGA 4800 AAGAGACTCT ACCTCATGGA GTAAGGAGAG GCTTCACAGA GGCAGGATTG CTATTAGTCT 4860 TCAAAGATGA GGTATTTGCT AAATGAATGA GACAAAGGGA TTGGGGCCAC ATTACAGGGA 4920 AATTGAGGTA TGTAATAGCC TGGTGCAGGT TAAGAGTGTG GACTCTGAAA CCAGACTCAG 4980 CCTGGAATTG AATCCTGGCT GTGTGATGTT GGGCCAGTGA CTTAACCTCT CTGTGCTTTT 5040 ATTCACTCTT CTATAAAATG GGGATTATAA TAAACCTACC TTATAAGGTT ATTATAACAG 5100 TCAGTAAATA TAAAAATAGA AGTTTTTGGA TGATGACTAT CACATCAGTA AACACTTGTT 5160 TGCCATTATT TTTATTACTT GACTAAAAAT ATACCAAAAA GACCATCCAA GAAAACCCTT 5220 TAAGCTGCTA GTGCAGAAAG ATTCCCCTTG TGTTTGTGTG CTGGGGGGTC AGTGGTGCCT 5280 GTGGCCCACT GGAGAGGAGA CAGCTATGGC TGGAGTGATT CTCAAACTTC AGAATGTCTA 5340 AAATCATCAC ATGGACAACT TATTAAGGAA AGCAAATGCC TGGGCTCCAT CCTCAGAGAG 5400 TCTCATTCAC TGGGTCAGGA TAGAGCCCAG GAATCTTTAC CTTAAAGAAC CATCCCACCT 5460 CCCACCTCAT ATGATCCTTA TGCAGGTGAT CTGGGGCCCA CACTTTGAGA AATAGACTCA 5520 GGTCAAAGTG GCTCTAACTG CATCTCATTT CTTACCTGGC ATATCTAATA GTAGAGAAGA 5580 AGACAATGCT AAGATTTTTG TTGGAGATCT TTTGCTGGGA TTGCTGCTTC ATTCATTCAC 5640 TCATTTATTT ATTTATTTAT TTATTTTGAA ACAGAGTCTC ACTTTGTCAC CCAGGCTGGA 5700 GGGCAGTGGC ACAATCTGAG CTCACTGCAG CCTCAGGCTC CTGGGTTCAA TCGATTCTCT 5760 TGCCTCAGCC TCCCGAGTAG CTGGGATTAC AGTCATGCAC CACCACGCCC AACTAATTCT 5820 TGTATTTTTA GTAGTGACAG CGTTTCACCA TGTTAGCTAG ACTGGTCTCG AACTCCTGAC 5880 ATCAGGTAAT CTGCCTGCCT CGGCCTCTCA AAATTAGTAG CTGCAATTAC ACGTGTGAGC 5940 TGCCGTGCCT GGCCTGCTGT TTCTTTTAGT TGGGCCTCTT CTGTAATAGA GTGTGAGAAT 6000 TCTGACTTGC TGCAACAGTC TGCTTTGAAG CAGGGCTGTG TTTACACTGG TCAGATGTGG 6060 AATTGTGGGG CACACTTAGC AGCTTCCTTC TCTAATTTTT CTGTATTTTC AGGAGAACAA 6120 TTTTAAAAAA TTTAATAAAA ATGCCTTAAA AATTAACATT ATTATAAGAT GAATCCCATT 6180 TTTCTAATCT TGTAAATTAA AAACAATCAT AAGCATATGA GCACCTGCAC TTAGGGAATC 6240 AAGGTTGGCA AAGCTAAACA CTTCCAGCTC TAGGTGATTC GCGGCAATAC AAATGGAGCT 6300 GGACTTTGGC CACAGTGCAA AAATATTGAT CTGTTGTTAG ATGCTCTGAA GTTTCCAGAA 6360 AGAATTGGTT CTGCCTGCTG TGCTTCAGTG CTTAAGGGAA GTGGTTCCTC AAAATGTTAG 6420 TTTTTAAGCC CAGCTTTCTT AAATAGGAAG ATTCTAATAG TAGCAAAAAT ATAAACTGCT 6480 TCTAGGTTTA AAAAGGACCC AGCACACAAT GGTTATCACA CACCTTTCTC CTCAGGTGAT 6540 GAGTGGATGA GTGGCCTGGT GTATTTCATA ACATCTCCCA GGTCCAAATG CTAAAGCAAT 6600 TGCTGAAAAG ATACCATGTG TACCGGAACC TTGCAGAGGT ATTTTGTTGG CATAAAAAGA 6660 AATATTGATC ATCTATAGTA AAAATGGTTC TACTTTAATA CTACTGAGAA AAGATTTTCT 6720 TTTCCCAGAT CTACATCCTG AATCTTCATG AAGACAAGAT CCCCTAAACT TCCACTAACA 6780 CCATAATGTG TGCTGTCCTT TGTAATGTAG TCCACAGATC TCATAAACTG TCAGAAATAG 6840 CAGAGATTGT AAGGTCATCC ACTTCCCCTG TAAGGCCTGC GTCCCTCACT TACATCCCTA 6900 ATAACGTCCT CTAACCTCTG CTGGAGGGCA GATTTAGCTG CCAGCTGGGA AGAGCTCTGC 6960 CCTAGTCAAC ATTTTTATCT GTGGCTTTCA GATGAGAACA CTGGATGCTT ATCTGAAAAA 7020 AGCTCCTCAG GCTGGAGGGA GGGATTGGCT CTAACAAGAT GCAATGTGAT AAGAATAAAA 7080 GCGAAGCCAA ACTCTAGGCC CAAAGGCTCT AGCAACACAC TTTTGAGAAC CTTGGAGACG 7140 AGTTTTGGCT GATGCGAGCT TCTCCGCCTG CTAAAGTAGC CCATTCCATT TGGACGGCTC 7200 TAGAGGCTGG CATGTTCTTC TCCACGTTGT GTTAATGTAC TCCAGTTTCT TCCTGCCATG 7260 AACTGGCATG CCCTGGCTCC TCCTACCTTC CCCACTTTAA GTCTTCCCTC CCTCCTTCTG 7320 ACCTTCCCAT TCCAGCCACA CTGGCCTTTT GTCTGGTCCT AACAAACCAT GCCTTTCCTG 7380 CCTCCAAGCC CTACACCTGC TATCCATCCC TCTGTCTGAG AGACACTCCC ACCCCTTCAC 7440 AAAGCCTGTT TCTCATCCTT CCAGTTCAGA TGTCTTCTCA GCTTGCCTCA ACTGACCTCT 7500 TTCAGCTATT CTCACTCTTT GTACTCTGTT CATTTCCTTC CTGGCAGTCA CCATAATTTA 7560 TCTTTATTTG AATCAATTTC TTAGTTGTAT TATTTAGTTA TTTGCACACT CTGTCTCTCT 7620 GTGCCTTTCT TATTCACTGC AGGCTTTCTT ATGTAAGTAA TTTATTTACT TAAATTTTTA 7680 AAAATAATTT CAACTTTTGG CCGGGCACAG TGGCTCACGC CTGTAATCCC AGCACTTTGG 7740 GAGGCCGAGG TGGGTAGATC AGCTGAGGTC AGGAGTTCGA GACCAGCCTG GCCAACATGG 7800 TGAAATCCCA TCTCTATTTA AAATACAAAA ACTAGCCGGG CGTGGTGGTA TGCACCTGTA 7860 ATCCCAGCTA CTCGGGAGGT TGAGGGAGGA GAATCACTTG AACCGGGGAG GTGGAGGTTG 7920 CAGTGAGCTG AGATCACGCC ATTGCACTCC AGCCTGGGGC ACGAGAGTGA GACTTCATCT 7980 CAAAAAAACA AAAAACAAAA AACCCCTGCT TTTCAGAGGG GCTGAACTAA TTTACATTCT 8040 CACCAATAGT GTATAAGCAT TCCCCTTTCT CTACAGCCTC ACTAGCATTT ACTTTTTTAA 8100 AAAACTTTTT AATAATAGCC ATTCTGACTG GTATGAGATG GTATCTCCTT GTGGTTTTCA 8160 CTTGCAATTC TCTGATGATT AGTGATATTG AGCATTGTTT TATGTTTGTT GGCTGTTCGT 8220 ATGTCTTCTT TTGAGAAGTG TCTTTTCATA TATTCTGCCC ATTTTTTGAA TGGAGTTGTT 8280 TTGTGCTTGT TGAATTAAGT TCCTTATAGA TTCTAGATAT TAGACTTTTG TTGGATGCAT 8340 AGTTTGTGAA TATTTTCTCC CATCCTATAG TTCTGTTTAC TCTGTTGATA GTTCCTGTTT 8400 TGTTATGTTT TGTTTTTTTG CTGTACAGAA GCTGTTTAAT CTAATTGGTC CCACTTGTCA 8460 ATTTTTGTTT TTGTTGCAAT GGCTTTTGAA TTTTAATAAT AAATTCTTTC CTAAGGCTGA 8520 TGCCCAGAAC AGCATTTTCT AGGTTTTCTT CTAGGATTCT TATAGTTCAA AGTCTTATAT 8580 TTAAGCTTTT AATCCACCTC AAGTTAATTT TTATATATAG TGAAATGCAG GGGTCCTGTT 8640 TCATTCTTTT GCATGTGGCC AGCCAGCAAT CCCAGAACCA TTTATTGAAT AAGGAATCTT 8700 TTCCTCATTG CTTATTTTGT CAACTTTGTC AAAGATCGGA TGACTGTAGG AGTGTGGCTT 8760 TTTCTGGGTT ATCTACTCTG TTACATTGGT CTATGTGTCT GTTTTTGTAT CAGTATCATG 8820 CTGTTTTTGT TACTATGGTC TCATAACATA GTTTAAAGTT GGATAATGTT ATGCCTCTGC 8880 TTTGCTGTTT TTGCTTAAGA TTGCTTTGGC TATTGAGGCT CTTTTTTCAC TTCATATGAA 8940 TTTTAGAATA GTTTTTTCTA ATTCTTTGAA AAATGACCTT GGCAGTTTGA TAGGAATAGC 9000 ATTGAATCTA TAGATTGCTT TGGGCAGTAT GCTATTTTAA TGATATTGAT TCTTCCTATC 9060 CATGAGCATG GAATATTTTT CCATTTGTTT GTGTCATCTA CTATTTCCTT TAGCAATGTT 9120 TTTTAGTTTT CCTTGTAGAG ATCCTCCTAG GTATTTCATT TTTTATGTGA CTATTTTAAA 9180 TGGGATTGCA TTCTTCATGT GGCTCTCAGC TTGAATGTTA TTGGTGTATA GAAATGCTAC 9240 AGAGTTTTGT ACACTGATTC TGTATCCTGA AACCTTACTG AAGTCATTTA TCAGTTCTAG 9300 GAGCCTTTGG CAAAGTCTGT AGTGTTTTCT AGGTATAGAA TCATATCATT AGCAAAGAAA 9360 GATAGTTTGA CTTCTTCTTT TCCTATTTGA ATGCCTTTTA TTTCTTTCCC TTGTCTGATT 9420 GCTCTTCCAG TACTACGTTG AATAGGAGTG CTGAGAGTGA GCATCCTTGT CTTGTTCCAC 9480 CTCTCAGGGG AAATGGTTCC AGCTTTTGCC CATTCAATAT GATGTTGGCC ATGGGTTTGT 9540 CACAGATGGC TCTTATTATT TTGAGGTGTA TTCCTTTGAT GCCTAGTTTG TCAAAGGCCT 9600 TTATCATGAA GGGATGTTGG ATTTTATTGA AAGCTTTTTC TGGGTCTTAT TTGGTGAATT 9660 GCATTTATTG AATTGTGCAT GTTGAGCCAA ACTTCCATCC CAGGGATTAA ACCTACTTAA 9720 TCATGGTGTT AACTTTTTGA TGTGCTGCTG GATTTGGTTT GCTAATTTTT TTTTTTTTTT 9780 TAAGATGGAG TCTCGCTCTG TCGCGCAGGC TGGAGTGCAG TGGTGTGATC TTGGCTCACT 9840 GCAAGCTCCA CCTCCCGAGT TCATGCCATT CTCCTGCCTC AGCCTCCCGA GTAGCTGGGA 9900 CTACAGGCAC CCGCTACCAT ACCCAGCTAA TTTTTGTATT TTTTAGTAGA GACAGGATTT 9960 CACCATGTTA GCCAGGATGG TCTTGATCTC CTGACCTCGT GATCTGCCTG CCTCAGCCTC 10020 CCAAAGTGGC TAGTATTTTT TTAATTACTA TTTTTTCTCA CCCTTGCTGC CATCTTATGA 10080 TTTTCTAGTA TTTTGTTGAA GATTTTTGCA TCTATTTTCA TCAGGGATAT TGGCCTGTAA 10140 TTTTCTTTTT TCATTTCATC TTTACCACAT TTTTGTATCA GGTTCATACT GGCTTCATAG 10200 AATGAGTTCA GGAATGGTCC CTCCTCCTCG AATTTTCTCT GTAGAATTAG TACCAGCTCT 10260 TTGTGTGTCT GGGAGAAGTT GTATGCCAAT AATTTAAATG CAGTTAATAT TTACTGGACA 10320 ATTTCCTCCA GATAATTGTA TATGATTTTT GGTCCACCCT GAGTTGATAC ATGTATTTTA 10380 ATTGTATCAT GGTATGAAAA GAGCAAGAGT TATTTGGTCA CCTAGTCTTG CCTATAGATG 10440 TTGCCTAATG ATTCAAAGTA GATATTTTGG GAGCCTTAAC AGGTGCCGTG GACTAGGCAG 10500 TTTTGTTTTT TTTTTTTTTT GAGGGACAGA GTCTCGTTAT GCTGCGCAGG GCTGGAGTGC 10560 AGGGGCATGA TGTAGGATCA ATGCAACATC CGCCTCGTGG GTTCAGAGCA ATTATACTGC 10620 ATCAGCCTCC CCAGTAGCTG GGACTACAGG CTCACGCCAC CACGCCTGGC TAATTTTTGT 10680 ATTTTTAGTA GAGATGGGGT TTCACCATAT TGGCCAGGCT GGTGTTGAAC TCGTGGCCTC 10740 ATGATCCACC CGCCTCGGCT CCCAATGTGC TGGGCTTACA GGCGTGAGCC ACCGCACCCG 10800 GAGATTAGGC AATTTTATAT TCCCAAATAT CCAACTCTTC TGACCCGCTT TCTCAGCCTG 10860 GGTGTATCAG GCACAAGGCC TGTTCAGATT ATGTGGTCTC TGAAGATATG GCTCTCCAGG 10920 GTTGACAATG TGGATAAGGA TTCACCTGGT TTAGGATTTA CACATTCGCC TTGAATGTCT 10980 GTTGCACCAA GTAGACAGTC CATCCCAACT TGGCCATTTG GTCAGAGCTG TAAGGAGACA 11040 AGGAGGTGGG CAGCCGCTGC TGTGAACTGC TTGGACAAAG ACTGCCAAAT AGCTATCAGA 11100 CAGTGTTAAC AACAGCTGAT TTAGGTTTGA AGGGGGCAGT CTCTTGGGCC ACTTACTATG 11160 CTGCATCATC CTCTTTGGAA AATGCTCTTC AGGTAACTGC CTAACAGACT GAGAAAATAA 11220 AATGCTCACA GAGAAAAAAG ACCCGGAAAG TCTGACTTCT CAGAGCTCAG TGTTTAGGTG 11280 CAGAACTGGA TTGTGAAAGG ATTTTTAAAT TTTTTATATT CATTGCAGGG AACATTCATT 11340 TATTCCATCC TTCTCCACTC CCACCTGTCT GTCGTTGTCT TTGTCTCTGT CTCCCCACCT 11400 CTCTCTCTAG ACACACACAC GCACACACAC ACACACACAC ACACACACAC ACACACACAC 11460 ACACACACAC ACACACACAC ACACACACAC CCCTATTCAT TGCCAACAGT AATAGAGTTG 11520 CTTCTTTACT TCTTGGAGAG AAAAGCCTCA ATCTGAGGAA GCTGTGCTGA CTAGCCTTGC 11580 TCTTAATCAT GGAGACAATG CTTTATGCCT TTATCTTTGC ACAGCTGAAA GCCATGGCAG 11640 AAGCAGTCCT CTAAACGAAA TAAAATAGAA AGGTTCCTGC TAAGCCCTGG CAAATGCAGC 11700 CTTCTATCCC TCCCCCAACA CTCACAGCTT CTGAGCAAGA TGTTGCTGCC TTCCAGGAGC 11760 TGGGTGATGG GCAATAATGA GCAGAGCCAC GTGAAGGAAA GATGGGTGAA GAAATGTGTG 11820 TGGAGTCATG CTGGCTGCAC TGACCATGAA ACAAAGGATC TACCCCTCTA GTAACTGCCC 11880 TACTCCTTTG GTAACTGTTC TGAAATTATA ACTTGCCAGA AGTTCAGAAG GACCTAGTGC 11940 AGGTATTAGA GGAAATTCGT AAGATTGAGC CATTTATTCC TGCACAGATA CATAATAATG 12000 GACACGGGCC ATGGTGGCCA GCATTCTTGC TCTTGACAAT GGTGAAGGGA AGGGTTGTAG 12060 GTCATGGCTA TGCTCTCAGA ATTATAATGG AAAGAAACAG CTCCTGAGTG TTTACTATGA 12120 GCCAAGGGCT GTGCTAAACA CTTTACCATA TGATGACATC TTTTTCTCAC AGGTATCAAA 12180 AAACAATAGG ACATACCGGA TAGCTACAAT CTTTGGGCCC CTGCAAACAC AATAATGTGT 12240 ATTCTCTTCT TCAAATCCTA CATATTGCTA CAAACTGTAT CCCTGAGGCA TATTCATTGT 12300 AAAATAAAAA CATATAAAGT ACTACTTTTG TTTTTTGAGA TGGAGTCTCG CTCTGTCACC 12360 CAGACTGGAG TGCAATAGCA TGATCGTGGC TCACTGCAAC CCCCTGCTCC TGGGCTCAAG 12420 TGATTCTCCT GACTCAGCCT CTCAAGTAGC TGGGATTACA GGCGCACGCC CCCATGCCTG 12480 GCTAATTTTT GTACTTTTAA TAGAGACCAG GTTTCACCAT GTTGGCCAGG CTGGTCTCAA 12540 ACTCCTGACC TCAAGTGATC CACCTGCCTC GGCCTTCCAA AGTGCTGGCA TTACAGCTGT 12600 GAGCCACTGC ACCCGGCCCA TATAAAGTAC TACTAATGTA ACAGGGTGCT AGTCCAGACA 12660 GTGACCACAC GTGGTGTTCA TTGAAGGCTG GACTAACAAC TCCAGCCTCT CCGCCATCAC 12720 AGAGTGATGA CTGCCTTCCC TGAAGCAAAG CTTCTGGTTC AAGGAAAGGC CAGTAAGTGA 12780 CTGCTCTTTG TTGTATACAT GTTAGATGAT CAGGCCTCAA GAAAAGTATA AAGAGATCTT 12840 TGTGCTCTCT GGGACTCAAA AAGCTGCACT CTTTGGGGGA AGGATAGCCA GGTAAAAGTG 12900 GCCCAGGTAA AGAGGGCCTG GTACACCTGG TTCTGCAAGA TGGTAGACAC AAAAATGAGA 12960 GCTACATTTG GAGCTTATGT GCCCCTAACT CTGTACATAA CCTGCAAGAT CTAATTACTA 13020 ACAACTGGAA TCTTGGAAAC ACCTGTAGTA CATCCTTGGC TAAGGTTAGC CCCAACAGAG 13080 AGGGCTCTCC TCTTACAGAG AACCATTACA TTTGTGCCTT CATCCTAGAG TAGAAAAGGC 13140 ATGATCAGAC TACTAAAAAG ACATCAGGAA AGGGCCTGTG ACATCTGAGG GAAGTGGTTG 13200 CCCTCTCTGG GATGTTGGTT CGGGAAGAGG GGCATGGAGG AGTGCCTGCT TTAGATGGTC 13260 ATTCAGGAAC CCAGGCTGAT AGTGAGAGGT GAAGCCAGTT GGGCTTCTGG GCTAGGGGGG 13320 ACTTGGAGAA CTTTTGTGTC TAGCTAAAGG ATTGTAAATG CACCAATCAG CACTCTGTAA 13380 AATGGACCAA TCAGCAGGAT GTGGGCAGGG CCAAATAAGG GAATAAAAGC TGGCCACCAG 13440 AGCCAGCAGT GGCAAACTGC TCAGGTCCCC TTCCACGCTG TGGAAGCTTT GTTCTTTTGC 13500 TCTTCACAAT AAATCTTGCT GCTGCTCACT CTTTGGGTCT GCACTATCTT TATGAGCTGT 13560 AACACTCACC GTGAGGGTCT GTGGCTTCAT TCCTGAAGTC AGTGAGACCA CAAACCCACT 13620 GGGAGGAACA AACAACTCTG GACACGCCAA CTTTAAGAGC TGTAACATTC ACTGCGAAGG 13680 TCTGCGGCTT CACCTCTGAA GTCAGCGAGA CTATGAACCC ACTGGAAGGA AGAAACTCCA 13740 GACACATCTG AACATCTGAA GGAAGAAACT CCAGACACAC CATCTTTAAG AGCTGTAACA 13800 CTCACTGCAA GGGTCTGCGG CTTCATTCTT GAAGTCAGCA AGACCAAGAA CCCACTGGAA 13860 GGAAACAATT CCGGACACAT TTTGGTGACC CAGATGGGAC TATCACCAAG TGGTGAGTAC 13920 CATCAACCCC TTTCACTTGT TATTCTGTCC TATTTTTCCT TAGAATTCGG GGGCTAAATA 13980 TTGGGCACCT GTCAGCCAGT TAAAAGCGAC TAGCATGGCT GCCAGACTTA AGAAACTAAA 14040 GACACGGGTG TCAGACTTTC TGGGAAAGGG CTCTCTAATA ACCCCCAACT CTTTGGAGTT 14100 GGGAGCGTTG GTTTGCCTGG AACCAGCTTC CACATTTCCT GTACTTCTGG GCTGAGACGA 14160 GGGTCAACAT AGAGGAAAGC CATTCAGCTC TGGGGTCCCG ACAGCAAGTT GGTTGACCCT 14220 GTGGCCATGA TCACAACTCT CGAAGTCATG TTGCCCAAGC GAGACTCACC CATCTATCCT 14280 ATCTATCCTG ACTCTTGCTT CCTGGGTCCT AATGCCTGGA AGACAAAACT TCCTCTTGTC 14340 TCTGTTCTCC AAGGCTAGTC CCACTTCTAA AAACCACTCC CTGTCTCTGG TGCTTTTCTA 14400 GTTTCTCCTA TAAGAATGAT TTCTAGTATA AACTCCAGGA CTCTATTCTC TTCTTTAGGC 14460 ACCCGGGCTC ACCAATCAGA AAGCCATAAT TTTTGCCCAA AGCCCCATCT TAGGGGGGAC 14520 TATCTGGAAT TTTAGGATCC CTCCTCAGAC AAGCAGGCCT AACAAAAGCT ATTCCTGAAG 14580 CTAGGATATG GGGAGCCTCA GAAATGATAT CCTTCCTATT CAAGTGAGGA CAAAAGGCAT 14640 CACTCTTCCA ATTCTGGAGA TCCCTTCCCT CCCTCAGGGT ATGGCCCTCC ACTTCACTTT 14700 TGGGGCATAA CGTCTTTATA GGACACGGGT AAAGTCCCAA TACTAACAGG AGAATGTTTA 14760 GGACTCTAAC AGGTTTTCAA GAATGTGTCG GTAAGGGCCA CTAAATCCGA TTTTTCTCGG 14820 TCCTCTTTGT GGTCTAGGAG GACAGGTAAG GGTGCAGGTT TTCAATAATG TGTTGGTAAG 14880 GGCCACTAAA TCTGACATTC CTTGGTCCTC CTTGTGGTCT AGGAGGAAAA CTAGTGTTTC 14940 TGCTGCTGCA TCAGTGAGCG CAACTATTCC AATCAACAGG GTCCAGGGAC CATTGTGGGT 15000 TCTTGGGCAA GAGGTGTTTC TGCTGCTGCA TTGGTGGGCT CAACTATTCC AATCAGCAGG 15060 GTCCAGTGAC CTTTGCGGGT TCTTGGGTCG GGGGGTGGGG GGAACAAACA GACCAAAACT 15120 GGGGGCAGTT TTGTCTTTCA GATGGGAAAC ACTCAGGCAC CAACAGGCTC ACCCTTGAAA 15180 TGTATCCTAA GCCATTGGGA CTAATTTGAC CCGCAAACCC TGAAAAAGAG TGGCTCATTT 15240 TATTCTGCAC TATGGCCTGG TCCCAATATT CTCTCTCTGA TGGGGAAAAA TGGCCACCTG 15300 AAGGAAGTAT AAATTACAAT ACTATCCTGC AGCTTGACCT TTTCTGTAAG AAGGAAAGCA 15360 AATGGAGTGA AATACCTTAT GTCCAAACTT TCTTTTCATT AAAGGAAAAT CCACAACTAT 15420 GCAAAACTTA CAATTCACAT CCCACAAGAA GAACTCTCAC TTACCCCCAT ATCCTAGCTT 15480 CCCTATAGCT CCCCTTCCTA TTAATGATAA GCCTCCTCTA TCTCCCCACC CAGAAGGAAA 15540 CAAGCAAAGA AATCTCCAAA GGACCACAAA AACCCCTGGG CTATCGGTTA TGTCCCCTTC 15600 AAGCTGTAGC GGGGGAGGGG AATTTGGCCC AACCCAGGTA CATGTCCCCT TCTCCCTCTC 15660 TGATTTAAAG CAGATCAAGG CAGACCAGGG GAAGCTTTCA GATGATCCTG ATAGGTATAC 15720 AGATGTCCTA CAGGGTCTAG GGCAAACCTT CAATCTCACT TGGAGAGATG TCATGCTATT 15780 GTTAGATCAA ACCCTGGCCT TTAATTTAAA GAATGTGGCT TTAGCCACAG CCCGAGAGTT 15840 TGGAGATACC TGGTATCTTA GTCAAGTAAA TGATAGAATG ACAGCTGGGG AAAGGGACAA 15900 AGTCTCTCCC GGTCAGCAAG CCATCCCTAG TGTGGATCCC CACTGGGACC TAGACTCAGA 15960 TCATTGGGAC TGGAGTCGCA AACATCTGTT GACCTGTGTT CTAGAAAGAC TAAGGAGAAT 16020 TAGGAAAGAG CCTATGAATT ATTCAATGAT GTCCACCATA ACTCAGGAAA AGGAAGAAAG 16080 TCTTGCCTTC CTTGAGTGGC TACAGGAGCC TTAAGAAAAT ACACTCCCCT GTCACCCAAC 16140 TCACTCAAGG GTTAATTGAT TCTAAAAGAT ATGTTTATTA CTCAATCAGC TGCAGATATC 16200 AGGAGAAAGC TCCCAAAAGC AAGCCCTTGG CCCTGAACAA AATTTGGAGG CATTATTAAA 16260 CCTGGCAACC TTGGTGTTCT ATAATAGGGG CCAAGAGGAG CAGGCCAAAA TGGAAAAGCG 16320 AGATAAGAGA AAGGCCACAG CCTTAGTCAT GGCCCTCAGA CAAACAAACC TTGGTGGTTC 16380 AGAGAGGACA GAAAATGGAG CAGGCCAATC ACCCAGTAGG GCTTGTTGTC AGTGTGGTTT 16440 GCAAGGACAG TTTAAAAAAG ATTGTCCTAT GAGAAACAAG CTGCCCCCTC ACCCATGTCC 16500 ACTATCGCTG AAGCAATCAC TGGAAGCCAC ACTGCCCCAA AGGACAAAGA TTATCTGGGC 16560 CAGAAGCCCC CAAGCAGATG ATCCAACCAC AGGACTGAGG TGCTCAGGGT TAGCGCCAGC 16620 TCATGTCATC ACCTCACTGA GCCCTGGGTA CATTTAACCA TTGAGGGCCA GGAAATTGAC 16680 TTCTACTGGA CACTGGTGCG GCTTTCTCAG TGTTAACCTC CTGTCCTGGA CAGCTGTCCT 16740 CAAGGTCTGT TACCATCCGA GGAATCCTGG GACAGCCTAT ATCCAGGTAT TTCTCCCACC 16800 TCCTCAGTTG TAACTGGGAG ACTTTGCTAC AGATAGTAAG TATGCTTACC TAATCCTACA 16860 TGCCCATGCT GCGATATGGA AAGAAAGGGA ATTCCTAACT TCTGGGTGAA CCCCCATTAA 16920 ATATCACAAG GAAACTATGG AGTTATTGCA CACAGTGCAA AAACCCAAGG AGGTGGCGGT 16980 CTTACATTGC CGAAGCCATC AAAAGGGGAA GGAGAGGGGA GAACTGCAGC ATAAGTGGCT 17040 GGCAGAGGCA GGGAAAGACA AGCAGAAAGG AAAGAGAGAA AGAGCAGAAA GTGAGAGAGA 17100 AAGAGAGATA GGAAGTGATA GCAAAGAGGG AGTCAGAAAG AAAAGAGAGA GGAGAGAGAG 17160 AGGGGGAAAG ACAGAGAGAG ACAGAGGAAG AGACAGAGAG ACAGAAAGAG AGAAGCAAAG 17220 AGAGGAAGAG ACAAAGAAGG AGTCAAAGAG AGGGAAAGAG AAGTAGTAAA GAAAAACAG 17280 TGTACCCTAT TCCTTTAAAA GCCAGGTTAA ATTTAAAACC TATAATTGAT AATTGAAGGC 17340 CTTTTCTGTT AACCCTATAA TACTCCCAAT ACCACCTTGT TGTTCAGTGT TAAACAAGGG 17400 TTATTAGCCC AAAAGCCACT GAGGCCACTG ACAACCCGTA GCCTTCTTAT CCAAAATCCT 17460 TAACACAGCA GGTTTCCTAA CAGGGATCTA ATCTTAGGTC GACCAGACTG GAGAACTGCC 17520 TTCAGGACAG GATGATAGAT GGTTCCTCCC AGGTGATTAA GGAAAAAGAC ACAATGGGTA 17580 TTCAGTAAGT GATAAGGAAA CTCTTATAGA AGCAGAGTTA GGAAAATTGC GAAATAAGTG 17640 GTCTGCTCAA ACGTTGAAGC TGTTTGCTGT TTGCACTCAG CTAAACCTTA AAGTACTTAC 17700 AGAATCAGGA AGGAGCCATC TATACCAATT CTAAGTTAAT ATGGACTGAA CGAGGTTTTA 17760 TTAATAGCAA AGAAAATTAA AATCTCAAAC TTACGAGGTT TTCAAGTAAA GTAAAGTTTG 17820 GTAAAAGTTA ACAGCGTAAC ATGTATTATC CTAGTACCAC ACATTCTCTC AAAGGATTTG 17880 CTCAGACAGT TTGCAAAAAA GAACGAAATC TGTCCTTACT CTACAATCCC AAATAGACTT 17940 TTGGCAGCAG TGACTCTCCA AAACCGCTGA GGCCTAGACT CTCATGTTGA GAAAGGAAGA 18000 TTCTGCACTT CTTAGGGGTA GAGTGTTGTT TTTATACTAA CCAGTCAGGG ATAGTATGAG 18060 ATACCACCCA GTGTTTACAG GAAAAGGCTT CTGAAATCAG ACAATGCCTT TCAAACTCTT 18120 ATACCAACCT CTGGAGTTGG GCGACATGGC TTCTCCCCTT TCTAGGTCCT GTGACAGCCA 18180 TCTTGCTAAT AGTCGCATTT GGGCCCTGTA TTTTTAACCT CTTGGTCAAA TTTGTTTCCT 18240 CTAGGATCGA GGCCATCAAG CTACAGATGA TCTTACAAAT GTAACCCCAA ATGAGCTCAA 18300 CTAACAACTT CTGCTGAGGA CCCCTGGACC GACCCGCTGG CCCTTTCAAT GGCCTAAAGA 18360 GCTCCCCTCT GGAGGACACT ACCACTGCAG GGCCCCTTCT TCACCCCTAT CCAGCAGGAA 18420 GTAGCTACAG CGGTCATCGC CAAATCCCAA CAGCAGCTGG GGTGTCCTGT TTGGAGGGGG 18480 GATTGAGAGG TGAAGCCAGC TGGGCTTCTG GGTCAGGTGG GGACTTGGAG AACTTTTGTG 18540 TCTAGCTAAA GGATTGTAAA TGCACCAATC AGCACTCTGT GTCTAGCTAA AGGATTGTAA 18600 ATGCACCAAT CAGCACTCTG TAAAATGGAC CAATCAGCAG GATGTGGGCG GGGTCAAATA 18660 AGGGAGTAAA AACTGGCCAC CCGAGCCAGC AGTGGCAACC CACTCGGGTC CCCTTCCACA 18720 CTGTGGAAGC TTTGTTCTTT TGCTCTTCAC AATAAATCTT GCTGCTGCTC ATTCTTTGTG 18780 TCCACACTAC CTTTATGAGC TGTAACACTC ACTGCGAGGG TCTGTGGCTT CATTCCTGAA 18840 GTCAACAGAC CACGAACCCA CTGGAAGGAA CAAAGAACTC CCGATGTGCT GCCTTTAAGA 18900 GCTGTAACAC TCACTGCGAA GCTCTGCAGC TTCACTCCTG AAGTCAGTGA GACCACAAAC 18960 CCACCAGAAG GAAGAAACTC TGGACACACC TGAATATCTG AAGGAACAAA CTCCAGACAC 19020 ACCATCTTTC AGAGCTGTAA CACTCACCGC AAGGGTCTGT GGCTTCATTC TTGAAGTCAG 19080 CAAGACCAAG AACCCACCGG AAGGAACAAA TTCCAGACAC AGTAGGAAAT CTGTATTTTT 19140 GATCTGTGGC TTCCAGGGTT ACTCCAGTCA TTGAAGTCTC CATTGCAGCC TTAAGGAAAC 19200 AGAGAATGGT TTGGAGGAGC ACATGTGGGA ATTGTTATGG ACCAGGCTTG AGATGCACAT 19260 AGGGCATTTC TGATCAAACC TAGCTGGAAG CAGGGCCAGG AAATATAATC TAAGGAAGAC 19320 AGTTTTTGTA GACAGTAGTA GTCTTTGCAT CTGAGACATG TAGATTATCA AGCAATTAAT 19380 TAGAAAAAAT ATAGCCAGGT GCGATGGCTC ATGCCTGTAA TCCCAGCACT TTGGGAGGCC 19440 AAGGGGTGTG GATCACGAGG TCAGGCGTTC GAGACCAGCC TGGCCAACAT GGTGAAACCC 19500 CGTCTCTACT AAAAATACAA AAATTAGCCT GGTGTGGTGG CACGCATCTG TAATCCCAGT 19560 ACTCAGGAGG CTGAGGCAGG GGAATCTCTT GAACTTGGGA GGCAGAGGTT GCAGTGAGCC 19620 AAGATCACAC CACAGCACTC CATCCTGGGT GACAGAGCGA GACTCTGTCT CAAAAAAAAA 19680 AAAAAAAAAA GGAAAGGAAA ATATAATCAA GAATATTGAC AGGTAACATT TATTCAACAC 19740 TTACTATGCA CCAGGCAATA CACTAAGTGT TTTACATGGA TTAACTCATT TAATCTTAAC 19800 AATAGCCCTA TGAAGTCAGT GCTGTTATTA TCTCCACTTT ATAGATAAGG AAACTGAAGT 19860 ACAGAAAGGT CAAGTAGAGA AATGGCCATG CTTGCATTCT CAGTTTTTGA AGCAACTGTT 19920 ACAGGAATCT GGTGTGAGAA ATGCTCTAAC AAGATGTGAG TCAGGGGTTG GGAGGTACTG 19980 AGTCTGAGTT GGGCAGTTGG GGATGGAAGG ATGGATGAAG AACAGCTTGA CAGAGAAGCT 20040 GACACTTGGC AACTCTGTGG GACCTTGAAG GGTTAGAGGG ACTTCACCAA AGAAACTGGT 20100 GGTCAGGGAT ACGGGAGGGT CACGGCAAGG AGGGAAAGGA AACTGTACCA CAGCAGAGAG 20160 TCTGAAGCTA CTACAGTGTA GTTCAGCGTA TAAAGAATAA TTATTTTAAG GTAAACTTAT 20220 AACCTCATGC AAATATAAAA TGAACACGTG TCAAAGATCT TATTTAATTT ATTAATTAAT 20280 GAGGGAACCT GTAAGATGTT ACAGCCAGTT CAAAGGATAA TTCAAATAAA TCCATGCACA 20340 TATGTAGGCA ATAAGGAATG CTGAAATGAA TTTAAAAGTA GATGTAAACT GATTTATCCA 20400 CAGAGAAATA ATCAGTTGCA TTTCACATAA CAAAATTCAG TTGCTTTTCT ACAGAAGGAA 20460 TTGTTTGCAT CATTACCAAT TTTTCTACAA CTAACAGAAT TATAAAATAA CTCAAACACA 20520 ATGAAAGGCA GATATAACCC ACAATGGTAT GATAGATACA ATATCCACAT CCAGGATGTT 20580 TTTTTCTCAT TTCAAAGTCT TTCACAAGTT TTCCTGATAA GGGAGTGTCA ATAATACTGT 20640 ATGGCAGGCA ATAAGACTGG ATGGATGGTT GGGGCCAGGT TTTAAGGGGT AATAAATGCC 20700 ATGTAAAGGT ATGTGCATAC TGTGCAACAT GTCGGGGAAT CTCAAATTAT TGGTAGAGTA 20760 TGTAAGAAAC ACTTGTGGAG CTTGTTAATA AATTCAAATT CCCAGACCCA ACTCCTCAAG 20820 GGTCTAATAC AGTAGGTTTG GAGTAAAGCC TGAAAATCTG CAATTGTGCA AAAAA AA 20880 CCCAGGTGAT TCTGATACAC TTTGAGAAGC ACTGGTGGAA CTAATAGTCA CTGAACGTTT 20940 TTGAGCAGGG GAGAAACCTG AGGACGTCTA TGTTGCAGCA GTGGAAACTT GATTAGAAGT 21000 AGGAGAAGAT GCATGGTCTT AAAAGAATGC AAAATGATGG CTAATATTTG AGTGCTTATG 21060 ATGGGCCAGG GGCTGTGCTA GGCGCGTGGC ACACATTCAA TACGATGGAA GCCTGTACCA 21120 GTCAGTATTA GTGGGGTATC TTTAAGAGTG ACCAGAATTA AGGGGGGTTT TCACCAAAGC 21180 CTGAGGACTG AGCCTCCTCA TCCTAAATTC AGACACAATG CTGTACCTAT GCATTTGCCT 21240 CCAGGCTGTT CCTGGGCCTC CAGGGACTGG CCCAGGCTCC TGATAAATAG GGACTCCCAA 21300 CAACATAAAG CCTGGATTTT GGAACTTCCT GAATGTTACT CAGGCTTTCT AGTAACTGTG 21360 GAGATCTGAA TAATAACACA ATTCTAAGTT CCCCTACTCA TAAAGCTGCT CATCATTTAG 21420 ATGGGGTAAA GCACCTGAAA TACAATGAGC ATCACTATTT TCATTCATCC ATGAAATGAA 21480 CATTCCGGGG AGATCAGTAA GTTGATGTAT CACCCTTGAA CAGGGCAAAA TGAATACTCA 21540 CCAGGAATAT GTGGTATTTT AAAAAGAAGG CAAAGGGAAG AATAGTGGGG ATGGGGCAAA 21600 AACTTTAAAT AGATTCCCCC AATCATATAT GGCAATTGAA GATAATTAAA TTATCATTTT 21660 AATTGAGTAA GTACTCATAG AGCCCTCACT ATTTGAAAAT GAACTGCCTC CTAATTGTTA 21720 TTGTGCAAAT GTGATACATT AAACTTAAGC TATTTTAATA AAACATCCAT TTTCGGAAGC 21780 TGTAGTAGGT TCTCCCAGGT CAGATTTGAT AAGCCATAAA GAACAAATGC CAACTCCTAT 21840 TTTTCTATGG TGCTGGGAAA TAAGAGAGAA ATGTGTAATT CAAAGCAATC ATTTAATTTT 21900 ATCCAATAGC TTGATTCTCC TCTCTCTTCT AGCCTTTTAG CTAAGCTGTT ACCAAGTAAC 21960 CACACTAGTT GGCTTGAGTC TTACCACTGT TTCCCTGACC CCACAGTGGA GAGACTGCAT 22020 CTGTTAAAGA GCAGTTATGT AACCATGGCT ATGCTGAGCT GGGATTCCCA AGGCTTAGGT 22080 TCTTTCTGTG AATGACCTTC ACCAAGACAC CTGAGGTCTG TGTGGAACCA CAGGCTTGTC 22140 ATCTCTAAGG CAGAGTTGAT AATTCCATCT GTTTCTTGAG CCCACACTGA GAAAAAGATT 22200 ACATGACTGC AGTTATTTGA ATGCCTCATG GAAAGACGTC TTATAAATAT TATAATTAAT 22260 GTTATCATTA AGTAATGCTT CAATGCAGAT CTTCCAAGTA TAAATATCAG CTGAGTAAGA 22320 AGTCAATCTT CCCTGAAGCA AAATTGAAAT TTGTAAATGC GATTTCTGGG AGCTTATTTT 22380 GTAATACATG ATTCCAGAGT GTCCATAACA CACACAATTG TCTTTTTTCC CCTACATGGG 22440 CTATTTACAA CAAAATTGGA CTTATAATGT TTATTTCCAG GGATGACTAG AACTTTAATA 22500 ACAAACCTTG GGCCAGGCAT AGTGGCTCAT GCCTATAATC ACAGCACTTC GGGAGGCTGA 22560 GGCTGGTTAG ATTACTTGAG GCCAGGAGTT TGAGAACAGC CTGGCCAACA TGGCAAAACC 22620 CTGTCTCTAC TAAAAATACA AAAATTAGCC GGGTGTGGTG GCGCATGCCA GTAATCCCAG 22680 TTACTAGGTA GGCTGAGGTA CGACAATCGC TGGAACCTGG GAGGCGGAGG TTGCAGTGAG 22740 CTGAGATTGC ACTACTGCAC TCCAGCCTGG GTGACAGAGA AAGACTCTGT CTCAAAAAAA 22800 AAAAAAA AT AATAATAATA ATAATAAACC CTGATGAAAG GTTTCTAAAA TGTTTTCATC 22860 TAATGGTTTT CTTGACAATT AAATTTTCTA TATAATGTCA GTTCATAAAA AAACTGAGAA 22920 CGACCACATG TCATATCGAC TGCTTAAAAG AAAATACGTA TATTTACAAA CATATACACA 22980 ATACTGTCTT TTGTCTGGTT AGTTTAGAGG TTAGATAAAC TGCAGTATGT TGTAGTGGAC 23040 AGATCATAGA ACTAGGAGTC AGGATGTCTG GATTCCTAGG AAGCAATGAA TAGGTTGCAC 23100 GGTGCAGCTC AAGGTTATTC AAAGTGTGGT GCCCAGACCA GCATCATGAG TATCCTCAGG 23160 GAGCTTGTTA GAACTGCAGA TCCTTTAACT CATTGAATCA GAATCCCTAG GTGTGGGGCC 23220 CTGAAATCTG TATTTTAGCA GGCTCTCTGG GATTGTGATG TGCCTTAGAG TTTGACAACC 23280 ACTGGGTAGC TGATCCTGAC TTAGACTTAT CAGGCATGTG ATCTTGAACA AGTCACATAA 23340 TCTCACTGAG TTCAGTTTTC TTATGTTTAA AATAGGCCCA ATAATATCTA TTTCACATGG 23400 ATTGCTTTGA GGATTAGGCA AGAGATCTGT AACAGACACT GTAGAACAGT GTCTCTGGTC 23460 TACAGCTGAC CTTCCATAAA TGGTAGTTGC CTTGATTCTC TGCTCTGCCA CATAATAGCT 23520 GGTTAACTAT GAGCAAGTAA TTTAGTTCTT CTCAGTTTAG TTTCTTCCCC TGTAAAAGAA 23580 GGAAAATAAC TGTTATACTC CATTTCTGAA TTGCTATAAA AGTCATTTAA TTATGGGCAT 23640 TGAAGCTCTT TGTTCACTGT ATAAGGACTG TACATCTAAG GGATTAATGA GACCAGGCTT 23700 ATGATTTTAA GCATGGAGTA AATAGTAACA CTGACTCTGT TCTATGAACC ACATGGAAAC 23760 TCTAAAGAAT ATGCACATTT GAAACACAGG TATCATCTGG GGAAGGTGAT CTGCTCACCC 23820 AAACCAGTTC ATGAACATCA ATCTCCAGTG GCGTGCTGGA GCTAGCTGTA CCAGCTCATG 23880 AGGGCCAATT GTTTCATTTT TAGGAATTTT GTTTGCTGGT TAAAAATAGT CATTATTTAA 23940 AATTAAATTA TGTAAACAAT AATATTAGAT AAAATAAGTT AAAATAAAAA CAAAGGAACT 24000 AATTATCCCC AAACTCTTCC CCACCTAATT ATTTTACTAT CTGTGCCTTG GGATTATTTA 24060 CATTGATTTT ATCCATATGG TGACAATACT ATTCATATAT AAATGGTGTG CTTCTCTTCA 24120 TAACTCTACA TAGCCTGATG TCAGGCTAGT AGCTTGAAAT TGGCCACAGT GGGAGTGTGA 24180 GCATTTGTAC CATGAGGCTT GGCCAAGGCT ACAAATCCAG ACTTTTGTTT TTCCCTCCTG 24240 GAGAGCTGTC TGTTAAAAAT TTACCAACAC ACCACTGGTC TTACCTTTGT TAATTTACCA 24300 CAGTCCAGGT TCTGACCTAG ACTTAGAAAC CTGGATTTGT CAGCAAGCTG AGGATAGAGC 24360 CATTATTTCT AAGAAGGACT CACATTACCC AAGTGCAAAG CCTGATATAT ACCTTCAGAA 24420 TATCAATTTA TTAATTTACA GTGAAGAAAG CCACCCCAGG GCATTCCCCA GGGGAAGGCA 24480 AAAAGAGCTA GTTGCACATT TTGAATGTTT GATGACATTA GGGTAAGGTG ACACAGAATA 24540 TCCATTTCCA CAACTGAGAT ACCTGCTGCC TTAAGGAAGG GACAGGCAAG TCCTTGGGCA 24600 GGACCTTAGA TTGTCACTGT CCATCTTGCT GTAGGACTCT CCTTTCCAGG CATGACGATG 24660 GCCAACTCTG TCCTCCTACC CTACTGATGG GATTATCTTT TCTTGACACA TGGCAATGCC 24720 TCCAATCAGA GGCTGGTAGC TATTTTTAAT CTTCAGGGCA GTATTTTTCA AAGGGAAGTT 24780 CATGGACCAT ATGCATCTGT ATCATTTAGA TGTATATTAA AAATGCTTAG TCTTCCCCAG 24840 TTATACTAGA TCAGAATCTC TGTTGGTGGG GCCCACGAAT CGGTATTTTC AACAAATCAC 24900 TAGGTAATTT CTGTATATAC TATAGTGTGA AGACCACTGC TTGAAGGTTT CTTTGCATAT 24960 CTCCACTAAA TATAAAAAAT ATTGACTTCT AGATTTAACT CCCAAAGCAC TTGCATTTTT 25020 AAGTTTCTGG GGGCATTATA TTGTGGTACC CCTATACCAC TCACACTCTA GTCAGGAGGT 25080 ATATTATGGA CTGAATGTTT GTGTCCCTCC AAAACTCATA TGTTGAAGTC TTAGCTTCCA 25140 ATGTGATAGT ATTAGGAGAT GGTGCCTTCT GGAGGTAAAA TCAAGCCCTC ATGAATGGGA 25200 TTAGTGCCTT TAGAAAGAGA GCTCGTCACT GTCTTTCCAT CAATTGAAGA TGCAGTGAGA 25260 AGCTGGTAGT CTTGCATCTG GAAGAGGGCC CTCACACAAC CTGATCATGC TGGCACCTGG 25320 TCTCAGACTT TCTGCCTCCA GAACTATGAG ATGATAAATT TCTGTTGTTC ATACCCCACC 25380 CAGGCTACAA TATTAGGTTG CTGCAAAGTA TTTGTGATTT TTGCCTTTAC TTTTCAGGGC 25440 AAAAACTGCA ATTACTTTTG TGCCAACCTA ATATTTTGTT ATAGCAGCCC GAACTAAGGC 25500 AAGGGAGACT ACATCAGACA GTGTAGCTAT GTAAGTACAA ATGTATCCCT GTTGAAGGAA 25560 AACTAAGTTC TAACCCTGAC TTCAGGCCAG TAGCCACCTT TTCAATCTCT TTCATGAAGG 25620 GACCATTATC ATTATCACTG GTGGCAAAAA TAGAGCACGA GAATGGAATT TGCTTTTCTG 25680 TGAAATCTCA GTGTATACAG ATGAAGAGCA AGGGTTTGCT TTCATCTCTA AGAAGCAAAA 25740 GTGAGTACGG ACTGGCACAT TATCAGAGAA AGAATCATTC TAGCTCGGTG GGTCTTAACC 25800 AGGAGTGAAT TTGACTCCAG GGAACAGTTG GCAATGTCTG GAGACGTTTT TATTTGTTAT 25860 AGCTGGGGGA TGAGTGGGTG GGTTGCTACT GGCATCTAGT GGGTGGAGAC CAGAGATGCT 25920 GTTAAACATC CCGCAAAGCA CAGGACAGTC CCCGACAACA AAGAATTATC TGGCCCCAAA 25980 TATCAATAGT GCCAAAGTTG AGAAACCTCA TTCTAGCTTC CTTTTCCCTT CTACGTTCTA 26040 ATCAACTGTT GTTCTTTCAG CATTAGGATT CATCCAGCAG TCTCTTTCCC CAGCAATTTG 26100 TTGAAATTTT TTTAAAAATG GACTCATTTT AGTGTCACAA GAAAAAAATA CATTCACAGG 26160 AAAGGATGGG TCATTTTGTT TAATGATGTT TTGCCTTTCA CATAGCAAAA GCTTAATAAA 26220 GTATTTTTAA ATAAAATGGT GAATAGATCA AAACATTAAT TTCACATGTG TTTTAATAAA 26280 TAACAGGAAG ATGGCTATAT TATATAAATT GTTCTTGTAT ATGTCTTGAG TGGATCATCA 26340 AACACAAACG TATCTACATG CCTTTTCTTG TGAATAGATC TAATAATAAC GCTCTTCTAA 26400 AAACAAATTA AATGGATATT ATTTGCTGAG AATGTAATGC TTGTGTGAAT AGAAGCCAGC 26460 CCTGAATCCA AGCCCCCAGA TCTATTTAAA GAATTTGAAG AATGTCAGAA AAGCACGTGG 26520 CTTCAAGGTT AATGTGTAAG ACTCACAGAA ACTTGAAAAA TCACTATGAC TAAAAAGAAA 26580 GTATGAGCTC CCTGCATGCC TGTAAATTGG AATGACAGCC AAAACCAGTT AATTATAAAA 26640 ACAGCTAATT TAACAGGTTT TCAAATTTGT TTCTTTCTCC AAGTAGCATA TAGTCAATAA 26700 TCCTTAAAGA GAAAGCAAAG AAGGGGAAGC ACTGAACCAA ATTTGCTTTT TTGTACCTGC 26760 TCAGCTCAAA TGCAGAGTTC TCTACCTGGA AATTGACTGC TTCCATAGTT TGATAGCCAC 26820 AGAGAGATGG GAACAGAAGG AGAGGTATAA TCCCAGACTT GATTCAGCTA TAGAGAATGA 26880 CAATAGTGTC AGAGGCCTTC CAACCAGAGC GACTCCATCT TGAATACGGG CTGGGTAAAA 26940 CAGGGCTGAG ACCTACTGGG CTGCATTCCC AGGAGGCTAA GCATTCTAAG TCACAGGATG 27000 AGACAGGAGG TCAGCACAAG ACCTTGCTGA TAAAACAGGT TGTAATAAAG AAGCCAGCCA 27060 AAACCCACCA AAACCAAGAT GGCCATGAGA GTTATCTGTG GTTGGTCTCA CTGCTCATTG 27120 TATGCTAATT ATAATGTATT AGCATGTTAA AAGACACTCC CACCAGTGCT ATGACAGTTT 27180 ACAGGTACAT TGGCAACTTC CGGAAGTTAC CCTCTATGGT CTAAAAAGGG GAGGAACCCT 27240 CACCTCCCAG AATTGCCCAC CCCTTTCCTG GAAAACTTGT GAATAATTCA CCCTTGTTCA 27300 GCATATAATC AAGAAGTAAC TGTAAGTATC CTTAGGCCAG AAGCTCAGGC CACTGCTCTG 27360 AATGTGGAAT AGCCATTCTT TTATCCTTTA CTTTCTTAAT AAACTTGCTT TCACTTTACT 27420 GTATGGACCC CTGTGAATTC TTTCTTGCAA GAGATCCAAA AACTCTCTCT TGGGGTCTGG 27480 ATCAGGACCT CTTCCCAGTA ACAATAGTAG TAAGGGGTCG GGGAAACTGG ACAAAGGAGT 27540 TTAAGAAGCC TTAGATAAAG GGTCCTCATC ATTGTCATAA CATAAAATCA TGGACTCCTA 27600 GAATTTTATA GCTGATAGGA TTAGAAATTT CAAAATTCAA TTTCATTAAT TTTCATCTGC 27660 GAAAACAGAT GGCCAGAGAG GCCAAACAAT TTGTTAAGGA GCACTGAGGC GATGGAACAC 27720 CACACTGGAC CGCAAACCTC CTAGCAGAGT ATACAAGGCC TTTGATCTCC TCAGTCAGAA 27780 TGAACTAGAG CTTTCCAGGG GTACCCTTTC TGACTGTTTA GCATGTTTGC CAGTCTGACT 27840 AATTTTGAAG TTGCTTAAAT ATCTGTCATT TCCACTGTAT CATAATCTCC TCATTCATCT 27900 TCAATCTCCA ATGCCTTGAA CTCAGTAAAT GTTAGTTGAA CAAAAGTAAA TTGAACCCAG 27960 AATTTCTGAT CATAATCTGG AGCACTTTAA AATTGTCAGC TTACTGGGAA ACGGGATAAC 28020 ATGTGATTTG TCTTTGATTT TTTTTTTCTC ATATGCTTTT TCCACCTATA GATGCTACAC 28080 GAATGTTTTT AAAATCTGAT ATAAAAATTA AAATTAAAAA ATTAAAAAAA GAAAATTTGA 28140 TACAATGCTA CATTTAGAGT GTTGTGATTA GATTCCTTAA GTGTATCATG GTGATCTCTA 28200 CATCACGTGG TGATCAAATT GCTTTGGGTT TTAACACATA ACTGACAAAG GCTTGGGGAC 28260 ATGTAAGATC CCAAATACAT TTTTATTGAT TTTTTTTTCT TGTTTGTCCT CTTTTAAATA 28320 ACTTTTTTTT GTTATAAGAA TAATTCATGT TCAGTGGAGA AACCATAGAA AATAGTGACA 28380 AGTGAAGGAA TAAATTTAAA ATGACCCATA ATTGTACCAT ACATTCTGAT TTTTTAAACG 28440 CTGAACAAAT TAGCCTTGGG TAAGTACCAG GAATAGAGTG CAGCATTGAA AGTTAAAGTT 28500 TGGGGAAGGA TAGCTGACTT AAGAAATTAT CTAGTTAGAC ATTTTTTGGA TGGGGTAATT 28560 TTGCAGATGA CATTAGTGAG AGAAAGGACT TGCCACTCTC ACACAGCTAG TAGGGGTGTG 28620 GGAGGATATT GGAACCAAGT TTCAAGTCTT CAGTGAAGAA TCAAGGGAGA AGTTCTAAAA 28680 CCTAACAATA TCCCTCTGGA TGGACATTTA TTTTATTACT ACAATAAGCC ACACGGTGAG 28740 TCATAAGGAG CATTTCATTC TTCTAATATG TCTCTACTGT ATTTAGAATC TGATAAAGCC 28800 CTATTAGAAT TCATCTCTTT AAGAATAAAA GAAGCTGAGG AACTAAAGAG AGGGTTGGAA 28860 TAATCCACTA ATTATATCCG TTAAGCTTCA GTTACGCTAA TAAGGAATAT CACATGACTG 28920 TGGTGTGTGC TTGTTCTGAA CAGTAAAGTA CATGAGGAAA GATAAGATTC AGGGCTGAAA 28980 TGTCCTTCAG CATATGTAGG TAGTGGTGAT GAAAGTCATT AAAAGAAAAA TTGATTGAGG 29040 TATTTTAGTA AACAAAAGAA CTCACCACTT ACCCATCAGG AAGTGTATTG TTAATGCAGT 29100 GCTGTTCAGC CTTCTGGAAG AAAAGGTTTC TTCATGCTTC TCTCTTTAGC CTAATTCTTA 29160 TCCTGTCACT TTTCAGGCAA AATTAAAAAA AAAAAAAGAT TGAAAACGAT GCTCCTATTT 29220 TATTTGCTTC AAAAGAAACA GGCTGTTGCA TTGTGCTTGG AACAGTTTAC TCTTGGCCTT 29280 GATGTAAGTG TGAAAGGAAG CCCATGTAAT TGACTAGGCA GTATCTGAAG AAGCAGGAAA 29340 TACAGTGTTA AGAAAATGAA CAGGCATGAA AACCATGGCT ATTTGATAAA AGTAAATAAT 29400 TTCTGCAGTT CACATGTTCT CAGCATATTT TCTTTGATAC TGACTTGCTT AATATGACAA 29460 TAGCAGAACC ATGGTAGCTT GTAGGCATTA CTTTTCTTTT AATTTCTTTT ACATTTTGAA 29520 TTTACCAGCA CTCACATTTG TATTACTTTT GGGTTATACT GAGGATCTAT AACTTATAGA 29580 TCAAATACCT GACATATATA TGCATTCTCT GAAGTCTTAG GGCAGAACTA GAACATTCTT 29640 GTGAACATCA GTATAAGATA TTAAAATGGA AGTTTTGCCT AAGACTGAAG ACAATAAAAA 29700 TATCATAGTC TGAAATGAAT GCCAGCACAC CATACAGGAT TTAAATATCT ATACATATAT 29760 ATGTGTGTGT ATTATATATA TTTAATATAT ATCTGTGTGG GATAGGAAGA GGTAGGGGGA 29820 AATCAGTTTT ACAATTATTA AGTATTTCAC CCTTGACAAG AGTATATATA TTGGAAATCA 29880 GTTGGAGAGT ATTTTCAAAG ATAAATGTTA GTGTGCTATG AATGAATCCA CCCCTACCAC 29940 CACTGAGGCA GGGTAGGAGA GGCCTGTGCT CCTCAAGCAT AGTTGGAAAA GGACCTCAAC 30000 AAGACCACTT CAAGAGTCTA ATGTGTGGAG ACTGTTGCTT AGGGAGACCT TATGGTCTAG 30060 CTTCTGACTC ACAGCTAAGT CAGGGAGACA GGTTGGCTGC TCTGATCGTG GAGTCCAAAA 30120 GATGGCCTGC ACTGAAAAGC CTCATGAGTG TTGACTTAGG GCTAGTCTAA GAGGTCCCTG 30180 GAAGAAGAAA CACTCAGTAG GAGAGAAGCT GGAGGTACCT TCAGTGCTGA ATTGGAACTA 30240 GATTCATTCC CCCGTGGAGC AAATTACATA GGAAAGATGC CCAGTGATGG AGAGTGGGGG 30300 TGTCTCTAAC AATTACCCAC CCACTGCCCC CACCCTAAGA AAAAGAAAAT CACATACAAC 30360 CAGTCAGCTG TAAACATATG CCGAGCCTAG TAAACTCAGA TACTAAGTTA CCAGGGTACC 30420 TGGCAAGTAA GAACATTCCT GATTCCCTTC CTCTCTTCTC TTTGCCCTCC AACCTTAGTG 30480 GCTAGCAAGA TGGGGAGAGG AGGAGAAGCT GTAAGTGGGG AAAAAAGAGC AGCTTTCTCT 30540 CCTTTTCAGC TGCTGGATTC TCCCTCATCA TAGGCCTGAG CTGGGGAATC AGGAAGAAGG 30600 ATTCTTTTTA AAACTGAAGT AACGTTATCA TTTAATTTTA AAACATTTTA AATTTTGACA 30660 ATGTTGAGAT TAGATATACT AATTATTAAA CTAAGATTAT GTTTTGCAGC TTGAAGTGAT 30720 AAGAAAAACT CTTATCTAAG AGCATCCAGG AAAGTCGGGG GTTTCCTGAA CATCCTTTTA 30780 AATCCTTTGG AAGTCAGCTT TCAGAGAGGA TTTAAAGTGT AGACTGGGCC TTCAGAAACT 30840 TGGTTAATGT AGGGGTTTCC TATGCAGACT TGGGGACTAT ACCTTGTGTG GAAGAGAGAA 30900 AATAAGATTA TCTTACATTT TTCCCATTCC TTTTTCAAAA AGAAAGCTCA GCTAGCATGA 30960 AAGTTAAATT CAAAACGTAA TGGGTATTAT TTGCATATTC AAATCTAGTG CATATCATGT 31020 AAGTACTGAA TTATGGTATT CATTATTTCA AATGACAAGC TGGATTTTTT TTTCTTTCGA 31080 ATTTCACAAA TTAATTTTCC TTGGAACCTT TTGGTTTGGG CTTTAAGAGT TTAGGCTTTC 31140 ATCACAAAGA GAGGACAGCC TTGAAGATTA AAGTGTGTGG CTCTTCTCAA GATGTTCTTA 31200 GTCCAGCAAA GGATTCTATG CATATTTGGG CTTCCTTCTG TCTCATAACC TGTATTTCTT 31260 GATATTCTAT TTATATTCTG TAAGATTTTT TTTTTAAAGG AAAAATTCTT CCATGGTTGA 31320 AGGACATGTC AAAAATAGAG GATACAGTTT TATATCAAAG GAAGTTTCAT GATATGACTG 31380 TAGAAGCTCA TTTGACTTAA GACACATCAT TTCCTCATGG AAGTGTTAAA CAGATCTGTA 31440 CAATAAGGTT GGCAATCTTT GTGTAAAACA GTTTTTTTTC TCCTGCTCTA AAGAAAGTGT 31500 ATATTTCAAA ATGTGAATGT CAGCAGTCAG AAAATAGTAT TTTTTTAACT TCGTTTTCAA 31560 AGTCCTCAAA AACCTGTACC TAATCATGAA TTTTTTTTCC CACAGATTGT TTCTTCTTCT 31620 CCCTCCCAGA AACTTTGAAG TTTTTCTACA TGACACCAGG ACCTATGTCT TTTTTTAATT 31680 ACACAGAAAT GAAAGAAAAA AAGTGTGTTG TATCGTTAAC CAAATATATG AAATCTTTAA 31740 GCTGTATTTT TATTTTTAAC TTTGTTTTGC AAAGAGGCCA TTCCCTTTGG TTAAATAATT 31800 TGTTATTCAC AGTTTCCTTG TCCTCATATT ATCAAGGGGA AAATTGTAGA AATTTTAAAG 31860 GAAGCTCTAG GCAATGTTTT CATCCCTGAA TCTTTGGAGA GTTATAAAAA CAAACAGATT 31920 ACTGAACCTG TAAGAGAACC AATCGTGAAG TCATTACATC TAAGCATAAG CAAAATCTCC 31980 TCTTGGATCA TTAAGTTATA GAAGAAAAGA AAGCCTGCAC TTTGAAATTT AGATAAAGCT 32040 TGGTAACTTG TAAGTCAAAC ACGTAAAATT TTACAATTCA GGAATATCGA TAGCAGTTGA 32100 GTTTAATAGA CTTCTCACAT TCCAAATTTA AAGCTTCCTT CTCTGTGCTA ATAGAGATAC 32160 AATAGCAGTA GGCGTTTAAG AAGAATGAAT CAACAATTTA AAACTATAAT GTGTTTTTTA 32220 TTCATCTCCC TTATTCACAT ATATTTGTTT TGTTTTGAGA AGGAGTTCTG CTCTGTCGCC 32280 CAGGCAGGAG TGCTGTGGCA CGATCTCAGC TCACCGCAAC CTCTGCCTCC CGGGTTCAAG 32340 CGATTCTCTT GCCTCAGCCT CCTGAGTAGC TGCGATTACA GGCGTGCGCC AGCAACCCCG 32400 GCTAATTTTT GTATTTTTAG TAGAGACAGG GTTTCACCAC GTTGGACATC TTGGTCTCGA 32460 ACCCCTGATC TCAAGTGATC AGCCCGCCTC GGCCTCCCAA AGTGCTGGGA TTACAGGCGT 32520 GAGCCATCAC TTCTGGCCCT TATTCGCATA CAATTTAAAA ATCATCACAG AAGGTTTGAA 32580 AGAAGGAAGG GGCAGAAAAT TACCTACTTT TCCTCTCCCC AGCGATCTCC TTCAAATCTG 32640 TGCCTTTTCC TCAGGCCCAG GCCTCAATTT ACTGAGCAGT CACACCTCAC AGAGGGAGGT 32700 CTGGGCAATC CACTCTTGGT CACAGGAAAG CCATTGACCC TCCCACTTCC TCTCCTCCAC 32760 CTTGTTCTCA ACTCTTGACT TTGGGCTTTG TTTCTGTTCA AGTCCTAGAA CTGGTTTCTT 32820 TTATCAGGTT AAGTGATTAG TTCTCTTTCC CTCTAGTTGC TCTCACTCCC TGACTCTTGC 32880 CTTCTGTAAC AACTGGAGAC AACTCTTTCA AAACCAGCTC CAAGCCCCAG ACTTCTCTCT 32940 GGGCTTTAGT TCGTAAGGCA GGTGCCCTAC TGAGTGAGCC TAGATCAGAC AGAAACATAG 33000 CTGTTGGCAA GGATTTAGGT GAATTTCCTT CCATTGTTTT TCTAATACCT TTTTTTTTTT 33060 TTTGTAAATA TAACCATGCA CCTACACACA TATTTGAATA TCCTGCCTTT TTATTTAAAA 33120 TGACATGATA GGTCCGGGAG TGGTGGCTCA TGCCTGTAAT CCCAGCACTT TGGGAGGCCG 33180 AGGTGGGCAG ATCACCTGAG GTCAGGAGTT CGAGACCAGC CTGGCCAACA TGGTGAAACT 33240 CCATCTCTAC TAAAAATCAA AAATTAGCCG GGCATGGTGG CAGGCTCCCA GCTACTCAGG 33300 AGGCTGAGAT GTGAAAATCG CTTGAACCCG GGAGGTAGAG GTTGCAGTGA GCTGAGATCT 33360 TGCCATTGCA TTCCAGCCTG GGCAATAAGA GCGAAACTCC ATCTCAAAAA AAAAAAAARA 33420 AAAAAGACAG GATAAACATT CTAGATAGTC TCTATAATGG TCATGATTAA GACAATAAAA 33480 TAGTCTGAAA TTGTCAATAT ATATTAATAA TAATTTATTT GGCCATTCTG CCAAGTAGCA 33540 GACACCTGTC ATTCTGCCCA CTCAGCACCT CTCTTTCTTT TAGGGAAATG CTACCCACTC 33600 TTTGCATGGG TTCTGGATGG AACTGTTGAT CACAGTGTTT TCACTCCCCA TTTTGCCTCA 33660 CCAGAGGTAG ACAGAAGACC CAAGCCAGGC CAGTTACACA CAATCTTCAG ATAATTACCG 33720 TATTGATCAC AGTATCACCC CACTCAAGGC TTGGTTGGAG ATGAGCAGAA GAGACTAAAG 33780 CTGGGTCATT TTAATTAACA CCTGTACCCC AAAGAAAGAC TGTCAATGAG GCTTTTATAC 33840 CGACACTCCT GGTTTCCATT CTTCCTGATG CCATTCATTT GACGAACTAC CCAATCTTTC 33900 CAACAGTGTC TTTGGAAGAA AGATAGTCAG AAAAGAAGAT AGAGTTGTTT TCTGTTCTTT 33960 GCAACCAAGG AACTCTAAAT GATAGACTTG TTGCTAGGCA CTTTGGTTAT TTTTATTATC 34020 TTGAATACTT CTGTGATATA CTTCTTTGTG CATGCCTGTT TGTACGGATG TAGCTTTTTA 34080 TATATTTTAT ATAATTTCTC AGAAGTGGAA TTACTTAGTC AAAAGGTATG AACATTTTCT 34140 GATTCTTAAT ATAAATTGTG CAAATGCTTT TTAAGAAGAT TATACCAGTT TACATTTTGT 34200 GTTATATATA ACAGAAAGTA CTACTGAAAA ATATTACAAA AATTGTCTCT CTGTTCAGGA 34260 GGACTTGTAA TAGATGATAA AGTACTTGAA ATAGGAACAT AGAGCATTTT CAGTTTAAAA 34320 TAATTTCATT GGGTTATTTA CGGAATCCTT AGAATTATGG CCAGACATTT ATAGATGATC 34380 TGTACCAAAC CTAGTTGGTT ACATAAATTG CTTATTCAAC TGGCTTAAAT CTATAATAGA 34440 AAGATGACAC TTACTGAATG TTTAATATAC ACTTTGTCAG GGGCTTTGTA TTATTCTATG 34500 ACATCTTCAA AATGACCCTA CTTTCCTATT TTATAAGTAA GGACAGGAAG GCTTCAAGAA 34560 CATGACTAAT TTTCCCAAGG GCTGTACCAA AGCCAGAACC CAAATCTATA AGGCTTTTAA 34620 ACCTGCATTC TAAAACTGCA TCTCGGCCAT CTTATTCCTA CAGAACTTAA GGTTAGAAAG 34680 CCAGATTGGA GTCCCAATTT CACCACTTAG TAACCAGACA AACTTGAGGA ATTCACTCAA 34740 CGTCTTTGAA TCTCCATTTC CTAATCTTTA AAACTAAAAC AATAATACTG GCCCTACCTA 34800 TTTCCTAAAA TTTCGTGAGG CACATAGAGC TAGTGTGGTA GAGTGCTGTA CAGATGTCAA 34860 GTGTTAGCGT GAATTACTTA GATCCCTGAA CACCATGGAT GAATGTGTCT GACTGCTATT 34920 AGAGGTCATA AAGAATATTG GGGCCAGGTA CATTGGCTTA TTCCTATAAT GCCAGCACTT 34980 TGGGAGCCTG AGACAGGAGG ATCACTCGAG GCCACAATTT CAAGACCGGC CTGGGCAACA 35040 <BR> <BR> <BR> <BR> <BR> <BR> TAGTGAGACC CCTTCTCTAC AAAAAAA at AAGCAGCCAC GTGTAGTGGC ACACACCTGT 35100 AGTCCCACAT ACTCAGGAGG GTGATTTGGG AGGATAACTT TAGTCCAGGA GTTTCAAGGT 35160 GCAGTGAGCT GTGATTGCAC CACTGTACTC TAACCTGGAC AGCAGAGTGA GACCCTGTCT 35220 CTAAAAAAAA AGAAAAAAAA AATAATAATA ATAAAGAATA ATGGGCCTTG GGATACCCAC 35280 TCCTCTCTTT CTGCTCTGAG TTGTGAAGCA GTTGAGTTAC ATATGCATGT CCAATGGATG 35340 AGGTTGAAAA TATCAACTGG ATTGGAATGT GGCTTACTTG CGTGGCCACA ATGAGCTTCG 35400 TAACACTTCC TGACAGGGTG AGAAGACAAA CTTCCTCACC CAGTCACTGG CAGAGCTGGA 35460 CACTCTGTGT CTCTCCCACA GAACAACCTC TTACTGCATG GAGGTGGATG AAAAAGTCAA 35520 CCGAGAACAG GCTACTCCAA AAAGCAGAGC ACCAAAGGCA CCAGCTGGTC AGGTCCCCCT 35580 TCCTAAGTAA ACAATCACGT AATTCATTCG GGACAAAGCC AGAGAGGTGG TGTGGAGAAA 35640 GAGAGGGCAG TTTCCTCCCA AGTTTTTCCT GGAATTCTTT ATGGGAATAT GAGGTTTAGG 35700 GGAATAAGAC TTCCCTTTAA CAGTGAAGAA TCCCCAGCTC TATTGGTAAT AGGAAATCGC 35760 TTACAAGGAT CATGGGGAGT ATTTCCTCAG CTCGTTCTGC CTCCTACTTG GCTGAGTGGA 35820 ATGGAACCAT CTGTGGCTGC TGCATATGAT ATTGTCAACT TTGTCATTCC ACACCCACTC 35880 CTTGACGCCC TACCATGTGG TCATAAGACT CCCTTTAAAG TGTTCCTTTA AAAAACAAAA 35940 TGTGTTTTGT TTCTATAAAA TACAGCTCAA TGTCAGAACC CTTGTCTTGT TTGCTCTCTG 36000 ATGTAACCCT TTCACAATGT TTGGGCAGCT TATTCTCTCT ATTTCCCTGT AGGGTCCCAT 36060 CCAGGCCAAA GTGAGTGCCA GCCTCATTTG GGCAGCACAT GCCCTGTGGA AGGGCAGGAA 36120 GAGACGAAAG CTAATTGTAA CTTTGTGATT AGCTGTCATG GATGCCTGGT CCTGTCAATA 36180 GCGCTCAATA AAGCCAGAAG GCCAAGCGTT CGCTTCTGCA TACTGATTGC TGAGTCAGAT 36240 TTCTCAGTGC AGAAGGGCTT TCTAGGCAGT CAATTTTAGA ATATTAGTCT TGGTTCTTAA 36300 GTGGTTAAAA TCCCTAGCTG GTCTTTAATC TGAGCCTGGA GAATTTAGTT AGGGCTGACA 36360 TTCTGCTGTG ATATTTTTGC CCTCAATATA TATGTCTTTC CTCCATCTCT TAGATCCCTG 36420 AATCATAGAG ATATATATGT TATATAATCA ACTGTCTCCA GTCTCTAAGA GTGATAAGTA 36480 CACATTGTGT CAGGTTGAGG GGACAGGAGA ACTTTCAAAA GCCTTTCTTG CCCCTTTTTC 36540 CTTCTCACTG CCTCCCACTA AGTCCAGCCA CTTATTATTC AGCTGACACT ATCATCATGA 36600 CCATGAGTCT TTTGGGGCTA CCCTGGTTCG GATCCTTTTG GAGGTTTGTT GCTTAACTCT 36660 GTCTTCAGTC CTATGGAGCT GCTTTTTCAA TAAGTTTCTA TTTTGGCTAA AGTTGGCCAG 36720 AATCTCCTTG TAACCAAAGA ACAAATAAAA TACCAGCTTG CAATGTTCTA TGTTGCTTCC 36780 ACCAAACTTA TGCAGCACTT CCTATCTAAT CCACCTACTA GTCTTTTTTT TTTTTATTTT 36840 TTTGGAGACG GAGTCTCGCT CTGTTGCTCA GGATGGAGTG CAATGGTGCA ATCTCGGCTC 36900 ACTGCAACCT CTGCCTCCCG GGTTCAAGCA ATTCCCCGGC CTCAGCCTCC TGAGTAGCTG 36960 GGACTACAGG TGCATGCCAC CACGTCCGGC TAATTTTTGT ATTTTAGGAG AGAGAGGGTT 37020 TCACCATGTT GCCCAGGCTG GTCACGAACT CCTGAGCTCA GGCAATCCGC CCTCCTCGGG 37080 CTCCCAAAGT GCTGGGATTA CAGGAGTGAG CCACCTCACC TGGCCCCGAC CTACTAGTCT 37140 TTAGTGTTTG CTTCCTTCTA TTGGGTAATT GTCTGTTTAT ATGCATGTCT TGTTTCCTCA 37200 AATAAAATGT GGTCTTCTCA AGGGTATTGG CCCATGTTCT ATCCATCTGT AGATATCACA 37260 GCACCTAGCA GTGTCTTTCA CAGAGGAAGT ACACAACTGG CATTATTGAT TCATTGCTCC 37320 ATTTTTTCCT TCTTTATCCC CAGCATTTCT CAATAATTTC AAACATCTCC ATTGGAGTAC 37380 CGGAGAAAGC AGGTAGCTTT ACTTGCAGCT ATGTTTCTAT CCCCATAGTA ACTAAAAGAG 37440 GACCCAGAGA AACATGTTTA AATGCTGTCC TGTTATCAGG ACCTCAGCCT TCTGATGCTC 37500 CGTGGCTTGG GGGTTAATGC TTGATCATTT CCTCCCCAAC CTACACTGTG TACCTATGCT 37560 AGTCTCTTCA TGAGGACTAA GCCCCATAGT AAAAGGGCTA GATAAATAGA AAATCATTTT 37620 ATGTAATTAT AAGAATGAGA ATACTGAGTA TTACTGGTGT TTGTTTAGGA TAAGCACATC 37680 TTTATTTGTA TGAGAAAAAG AAAAAGAGAG TGAAAAATAT ATTAACGTGC ATATAGTTCA 37740 GGACCATGGA TTGCAAGTGA CAGAAACTCA ATTCAAACCA ACGTAAGTCA AAAGGAAAAT 37800 ATATTGGCTC ATGTAACCTT CTCACAGAGA GGGCAGGATG GAAGGGGCTT TGGGAACAAG 37860 AGAATTGTTC TCAAATTCTA GGAATACTAG GATTAGTCCA GGATGGGTCA CCTTCCTGTC 37920 CCTGAGGTGG TGGTAGCGAT GGTAGAGTCT TATGGGAGGA AAGAGTGCAT GTTAGGATGA 37980 AGGTAGGGCT AAGCAAACAA GGGCAAGGGC CACTATATCA TGCTAAAAAT GGTTTTTTTT 38040 GATGTCTTCC TTAATTTCAC AAATGCTTCC AACAAAGTAG CACACAGGAA AAAGAACATA 38100 GGGACTCTAC TGGTGGGTGC TTTTATCTTA AGCCTTGTAC TTGCTTTTCA CAGCTTACTC 38160 ACTGCTTGTA CCTGAGGCCA TATGCCCTGT AAAAGCTTCT GCAGGGTTTC TACTAAGCTG 38220 GGTTCCTTAT ATGGCTCTCT CCCATTTCTG TTGCCTCACT CTAGTGATCT TTCTCTTTTC 38280 CTCACCTCTG GGACTGGTGG CTGTTTGTAT GGACTGCCTT AGCTTTGCTT TGGGTTTTTT 38340 CCTGGGGACA ATGTCTTCAG ATTATCCTAG ACCAAATAAA CTACAGCCAC TGGGCCAGGC 38400 TCTTCCTCCT CCAACTGGAC CATGTTCCCA GGGCTCTTCA CCTTAGTTTA GGTCAAGCAT 38460 TCTTGGCAAA AGAAAGGCCT AGTTAACAAT AGACATTCTA GCAATTGATT CTTTTTGACA 38520 TGTTGTAAGA TCTATTCACA TTTTGTAATT AAAGCATTCC CCTATGGAAA CCAACACGAA 38580 CTAAGCTGCT CCTGGAATGC AGGGTGGCCT CCTCAATACA GGATGTTCTA GAGAGCTGTA 38640 TTTTGGGCAC TTAACTATTC TCCACTACTT AGGGCACAGC ACTGAAATTA ACACCACTAA 38700 GTTTGTCATG TCCATGTAGT TAGTCTCAGG CAGTGCAGCC TCAGGAGTGG AACTGACCTC 38760 TTATGTGTGT CCAGCCTTTC TTCCTTCAGA AGTCAGCTGT GTTTTCTGCT GACTCTCCAT 38820 AGGAACATCA GTCCTGAATC CTCAGACCAC CATCTGGAGT AGTAAGTGCT CCTGACAGTC 38880 CTAGAAGTTG TCTACCGCTG GATCTCCAAA GCGTGTGACA CACCGTGAGA GAGAAATGAG 38940 AAAGCTGGGC TCTTCAGGTA AATCTTGCTT TTTCACAAGC CCCCTAATTT TACTGCATAA 39000 TTATTTTGAA TTCACTGATA ATTTCTACAA TTTTCCCATA AGTCATCTAC ACACAATACC 39060 CTCTCATGCA ACACTTGGCT TTGCTAATAC ATATCTATTA TGAGAGCTGT GCTTCTTAAG 39120 CGTAAATGTT TTATATGCAC TAAGGCTCTT GGCTTACATA TAAAAGGGGT ATTGAGCAAT 39180 GTGATACAGA AGTCTTTTCT CCACAGGTCT CATATGTAAA GAATTCATTA GATTGGCTGA 39240 AATAGACTGA TCTGTCCATT TCTCTGCTCA CTTATCATAA GGAAGTCATT AGCTAAGGAA 39300 CAAAAACTAC AATCTATGTA ATTAGAAGAA CAAGCTGGTT TTGCTCAATA TAAAAATAAG 39360 AAAAAGAAAC CATGTGAAAG TCAAAATATT TGTTTAATCA GGTCATTGAG AATCTATTAA 39420 AAAGTATTTG AATTCTTTAT GATGAGAACT ATCTTGACTC AAGTGGACAG TGGTGAGCTT 39480 TTTGGCCTGT GGTCCCTACG TAGAAAGGAG GCTTTGTCAT AAAGTCTTAT ATGGTACAGG 39540 TGCCAAGTTA AGTGCCCAAG CTTGCTCTTA AAAGCATACT GGATTTTGTT TTAGACTTTT 39600 AGTGAACTGA AGGGAATAAA CAAATCCCTC TGGGAGAACT TCTCCTCCAT CCTTGGTGAA 39660 GTCATTCTGC CAGAATTC 39678 (2) INFORMATION FOR SEQ ID NO:4a: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 41008 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:4a: TGGTTGATTT GTNNATAAGG AAGTTTGGAA TCAATCCCGG AAGGAATTTT TTTTTTAAAA 60 AATTTTTTGG AAGGGTTTGG TAWTAAAAAA RCCAATTTGG GTTTTTAAAA ATAGGAATTT 120 TATGGGAAAA AATTTTCCCT TTTTTTTTTT TTAAGTTTTA GATGTTATGT TTCCTTATAC 180 TTAAAGTGGG TGTCTTATAG GCAGCATATA TCTGGGTCTT GATGTATTAT TTAATCTGAT 240 AATCTCAACC TTTTTGTTGG AGTGTTTAGG CCATTTACAT TTAGTGTAAT TATAGACATG 300 GTTTGATTTG CTATACCATC TTTTCATTTG TTTTATATGT GAGCCATCTT TTCATTGTTC 360 TTTTTTCATC TTTGACCATT TTCTTTAGTA CTGAATACTT TTTTTGTATT TCATTATATC 420 TATTGGCTTT TTAGTTATAC CTCTTAAAAT TTTTTTTTCT GTTTTATGTA GGATTTATAA 480 TATACATCTT TAACTTATCA CAGATTACCT TCAAATAGTA TTTTACCAGC TCAAGTGTAA 540 TGTAGAAACC TTACAAGAGT ATATTTTCAT TTCTGTCTCC TAATTTTTAT GCTATTGTCT 600 ATAATACATT AGGTTTGTTG TTGTTTGTTT TTACCTTATT GCTGTTGGCT GGGGTCAGCA 660 AACATTTTCT GTAAAGGGCT AGATAGTACA GGCATACCTT GGAGATACTG TGGGTTTGGT 720 TCCATACCAC CACAATAATA CAAATATGCA AGAAGTGGAT ATCACAATAA AGTGAGTCAC 780 ACAAGTCTTT TGGCTTCCCA GTGCATATAA AAGTTTTGCT TATACTACAC TGTAGTCTGT 840 TCAGTGTGCA ATAGTGTTAT GTCTAAAAAA ACACATACCT TAATTTTAAA ATGCTTTATT 900 ACTAAAAAAT GCTAACAATC ATTTGAGCAT TCAGTGAGTT GTAATCTTTT TGCTGGTGGA 960 AGGTCTTTTC TTATTGATGA CTGATCGGGG GTCAGGTGCT GAAGCTTAGG GTGGCTGTGG 1020 CAGTTTCTTA AAACAACAGT GAAGATTGCA ATATCAGTTG ACTCTTCCTT TCATGAAAGA 1080 TTTCTCTCTA GTGTGTGATG CTTTTTGATA GCATTTTATG CACAGTAGAA CTTCTTTGAA 1140 AATTGGAGTC AATCCTCTCA AACCCTGCTC TGCTTTAACA ACCTAAGTTA ATATAATATT 1200 CTGAATCCAT TGTTGTCATT TCAACAATTT TCACAGTGTC TTCACCAGGA GTAGATTCCA 1260 TCTCATTTCC TGAGATGGAA TCTTTGCTCA TCCATAAGAA GAAATTCCTC ATCTGTTCAA 1320 GTTTTATCAT GAGATTGCAG CAATACAGTC ATGTCTTCAG GCCTCACTTC ACTTTTAATT 1380 CCAGTTCTCT TGCTGTTTCT ACCACATCTG TGGTTCCTTC CTCCATTGAA GTCTTGAACC 1440 TCTCCAAGTC ATCCATGAGG GCTGGAATCG ACTTCTTCCA AATTCCTGTT AATATTTATA 1500 TTTTGACCTC CCATGAATCA TGAATGTTCT TAATGGCACC TGGAATGGTG AATCCTTTCC 1560 AAAAGGTTTT CAATTTACTT AGTCCAGATC CATCCATCCA GAGGATCCAC TTTCAATGCC 1620 AGTTATAGCC TTATGGAATG TATTTCTTCA ATAATAAGGC TTGAAAGTTG AAATTACTCC 1680 TTGATCCATT TTCTGCAAAA TAGATGTTGT GTTAGCAGGC ATGAAAGCAA CATTAATCTT 1740 TTTGTACATG TCCATCAGAG CTCTTGGGTG ACCAGGTATA TTGCCAGTGA GCAGTAATAC 1800 TTTGAAAGGA ATTATTTTTC TTAGCAGTAG GTCTCAACAA TGGGCTTAAA ATATTTGGTC 1860 CACCATTCTG TAAACTGATG TGCTGTCATC TAAACTTTGT AGTTTCATTT ATAGAGCACA 1920 GGCAGAGTAG ATGTAGCATA ATTCTTAAGG GACTTAGGAT TTTCAGAATG GTAAATGAAC 1980 ATTGGCATCA ATTTAAATCA CTAGCTGTAT TAGCCCCCAA CAAGAGAGTC AGCCTATTTT 2040 TTGAAGCTTT GAAGCCAAGC GTCGACTTCT CCTCCCTGGT TACAAAAGTC CTAAATGGCA 2100 TCTTCTTCCA ATATAAGGCT GTTTTATCTA CATTGAAAAT CTGTTGTTTA GTGTAGCCAC 2160 CTTCATCAAT GATACTATCT AAATCTCTTG GATAACTTGT GCAGCTTCTA CATCAGCATT 2220 TGCTACTTCA CCTTGTACTC TTATGTAATG GAGTGGCATC TTTCCTCGTA CCTCATGAAC 2280 CAACCTCTGC TAGCTTCCAA CTTTTCTTCT GTAGTTTCCT CGCCTCTCTC AGCCTTCATA 2340 GACTTGAGGA TAGTTAGAGA CTTGCTTTGG ATTAGATTTT GGCTTCAGGA AATGTTGTGG 2400 CTGGTTTGAT CTTCTATCCA GACCACTAAA ACTTTATCCA TATCAGCAAT AAGGCTGTTT 2460 TGCTTTCTTA TTATTTGTGT GTTCACTGGA GTAGCACTTT TAATTTGCTT CAAGATATAT 2520 TTCTTTGCAT TCACAACTTG GCTGACTGGT GCAAGAGGCC TAGCTTTCAG ACTATCTTGG 2580 CTTTTGACAT GCCTTCCTCA CTAAGCTTAA TCATTTCTAG CTTTTGATTT AAAATGAGAG 2640 ATGTAGGCCA GGCACAGTGG CAGGCACAGT GGCATATGCC TGTAATTCCA ACACATTAAG 2700 AGGCCAAGGT GGGAGGATTG CTTGAACCCA GGAGGTGGAG GTTGTAGAGA TCACACCACT 2760 GCATTCCGTC CTGGATGACA GAGCAAGACC CTTTCTCAAA ATAAAATGAG AGGTGTGCTT 2820 CTTCTTTTTG TTTGAGCCCA TAGAAGCCAT AGTATGATTT TTAATTGGCC TAATTTCAAT 2880 ACTGTTGTGT CTCAGAGAAT AGGGAGGTCT GAAGAGAGGG AGAGAGGTGG GGGAATGGCT 2940 GGTCAGTGGA GCAGTCAGAA CACACATAAC ACTAATAAAT TGTTTGCTGT CTTATATGGA 3000 TGTGGTTTGT GATGCCCCCA AACAATTACA ATAGTTACAG CAAATATCAC TGATCACAGA 3060 TCACCATAAC AGATATAAGA ATCATGGAAA AGTTTGAAAT ATTTTGAGAA TTAGCAAAGT 3120 GTGACACAGA GAAACAAAGT GAGCACATGC TGTTGGAAAA AATTGGTGTT GATAGACTTG 3180 CTCCATGTAA GTTTGCCATA CGCCTTCAAT TTATAAAAAA CACAATATCT AGGAAGTTCA 3240 ATAAAGTGAA GTGCAATAAG ATGAAGTATG CCTGTAAATA TTTCAGGCTT TCCAGACCAT 3300 AGGGTTTCTG TTGCAACTGC TCACCTCTGC CATTATAGCA TGAAAGCAGC TATAGAAAAT 3360 ATACATAAAT GAGGCCTGTA ATCCCAACAC TTTGGGAGCC CAAGGTGGAT GGATCACTTG 3420 AGGTCAGGAA TTCGAGACCA GCTTGGCCAA CATGGCAAAA CCCCGTCTCT ACTAAAAATA 3480 CAAAAATGAG CCAGGACTAC GCATGCCTGT AGTCCCAGCT ACTTGGGAGG CTGAGGCAGG 3540 AGAATCTCTT GAACCCGGGA AGGGGAGGTT ACAGTGAGCC AAGATTGTGC CACTGCACTC 3600 CAGCCTGGGC AACAGAGTGA GACTGTCTCA CAAAAAAAAA AAAAGGAAAA GAAAATACAC 3660 ATAAATGAAT GTATGTGGCT GTGTACCAGT ATATCCTCAT GCTCTAGCTT GCCAACCCTT 3720 GCTTTACACT GTCAGTTACC TTCTAAAGAG ATTAAAAATC ATAACAATAT CTATTACGTT 3780 TATTCACATC CTAGTGTCAT TTCTTCCTTA TGTAGAATCA AATTTCATTC TGGTATCATA 3840 TTTCTTCTTT CTAAATAATT TCCTTTAATA TTTTTTATAG CACAGGTCTA ATAGCAATGC 3900 ATTATGCAAT TCATTGCTAT TAGACCTGTG CTATAAAATA GCAATGAATT ATGTCAGTTT 3960 TTATTTGTCT GAAAAAGTTT TTTGTTTTTG AAATATACTT TTGCTGGGTA TATAAATCCA 4020 TGTTGCATAA CTTCTCTTTT CTTCAGCACT TTAATGAAGT CACTCAGTTA TCTTCTGGCT 4080 TGTATAGTTT CTCTGGCTGC CTTCAAGATT TTTTCATTGT CTTTAATTTT TAGCAGTTTG 4140 ATGTGTCTAG GAGTGATTTT CTTTGTATTT ATCCTTTTGG GGGCCTCTTA ATTTCTTTGA 4200 TCCTTTTTTT CTTTTTTTTT TTTTTTAAAC CATTTTGGGT CTTTCCCCCC ATTTGGGGTG 4260 <BR> <BR> <BR> <BR> <BR> <BR> <BR> AAAAAAAA A AAAAATAAAA TCATAGTTTA AAAAACTAAT TTTGGAAAAT TTTCAGCTAT 4320 CATTTCTTCA AATATTTATC CTACTCTATG CTCCCCTCCT CCCCTTTCCT TCTGTGACTC 4380 AAATTACAGG TATATTTAAC CATTTTATTT GTTCACGGCA CTTGGATGCT CTGCTTTCTT 4440 ATTTTTTGTC TTTCATTTTG GATAATTTCT ACTGACCTAT CTTCAAGTTC ACTGATTCTT 4500 TTCTCAGTCA TGTCTAGTGT GCTCAACGCC TGTTGAAGAA ATCCTTTGTC TTTAATATCA 4560 TGTTTTTTAT TTCTAGCATT TTCATGTAAC TCTTTGTTCT GGTTTCCATC TCTCTACTCA 4620 CTTTTTTTTT TTTTTTTTTT TTTTTTTTTT TTTTTTTAGA CAGAGTCTCG CTCTGTCACC 4680 CAGGCTGGAG TGTAGTGGCG CGATCTCGGC TCACTGCAAC TTCCGTCCCC TGGGTTCAAG 4740 TGATTCTCCT GCCTCATCCT CCCGAATAGT TGGAATTACA GGTGCCCACC ACCGTGGCTG 4800 GCTAATTTTT GTATTTTTTT AGTGGAAACA GGGTTTCACC ATGTTGGCCA GGCTGGTCTT 4860 GAATTCCTGA CCTCAGGTGA TCCACCTGCC TCAGCCTCCC CAATTGCTGA AATTACTGGC 4920 ATGAGGCACT GCACCCAGCT CTGCTGACAT TTTTTATCTT TTGCTGCATT TTGTCTACCT 4980 TTTCCATGAA ATCCTTTAAC ATAGTAGTCA TAATTACTTT CAATTCCTTG TCTGACAGTT 5040 CTGACATTCA AGTCTAGGTC TGTTAATACT TTGTGAATCT GTTAACAGCT TTTTTTCATT 5100 CTTGTCTGTG TGTTTTGTAT TTCTTGATTG TATGCCAAAT ATTGCCTGTA AAATAAACTT 5160 AGATAAGTCA TACTTCTATC CAGAAATAGC ACATTTTTTG TGTCCAGTCA TTATGTGGAG 5220 GAGTTGGGGC AGTCTATCAG TGGCTGAACT AGTTTGGATT TGTTGATGCT ATACTTAGAA 5280 TGCACCAGAC TTCCATTCAC TGCAAGAGTG GGCTGCTGCG CTTTGTGATT CATGTGAGGC 5340 CTGAATTGTG GAAGGGTTTT TCCTTAGTGT GTCCCTCCAT GCTCAGATTT CAGCAAGTCT 5400 TCATATCTGT GCCACAGAAG GAATCTGACC CATGCTCTTT TTGACCTCCC CAAGTGATCA 5460 ACTGTTGCTT GTTATAGCTT GTCATGGAGT AAGAGGGTGT TTTTTTAGTT TTCATCCTCC 5520 AGCCTTGGTC TTGGGCCCTG AGCTCCTAGA CTCCAGGAGT GGATGGAATC CAGTGATTTC 5580 TCAGTAATTC AGCCCCTTCT CCAGTAGTGG CAGATCTCTG CTTTGTATCA GTGCAAGATC 5640 CTGGGCTGAG CTCATTTTCT GCCCTTCCTC GAGTGGCAGA CAGCTCTTGC TTTCACCCTT 5700 CTACCAAAGG CAGTGCATCT TTTCTTGGGC CTCTCCCCAT TGAACTTATG ACTTTCACAT 5760 AAGAGAAGGG CTCATGTATC AGAGAATTCT GTGACTTTGT GCCACATACA GAGTCTCTCA 5820 GTTCTCTTGC CCTGCCCCAG TCTTTTTTGT GAGCACCTAG TAGAGACCCT TGGAGAAGAG 5880 CAAGGAAGCG AGTATGGACT TCTTTTGTGT CTGTCGATTG CTTTGTTTCT CAACTGCTAC 5940 TCTTGGACTT TAAGAATTCA TTAAAATTTC AGCTGTTTTC TTTTTTTCTT TCGTTTTTCT 6000 TTTTTTTTTT TTTTTTTTTT AGATGGAGTC TTGCTCTGTT GCCCAGGCTG GAGTGCAGTG 6060 GTGTGATCTT GGCTTGCTGC AACCTCCGCC TCCCGGGTTC AAGCGATTCT CCTGCCTCAG 6120 CCTCCCAAGT AGTTGGGATT ACAGGTGCCC ACCACCACAC CTGGCTAATT TTTGTATTTT 6180 TAGTAGACAC AGGGTTTCAC CATTTTGGTC AGGCTTGTCT CAAACTCCTG ACCTCATGAT 6240 CTGCCCGCCT CAGCCTCCCA AAGTGCTGGG ATTACAGGCA TGAGCCACCG CGCCAGGCCT 6300 CAGCTGTTCT CTTTTTACCT GCTGGGATGG CTAGTTTTCT GTGTCAACTT GACTGGGCCA 6360 TGGGATGTCC AGATATGTAA TTAAACAGTA TTTCTGGGTG TTTCTGTGAG GGTGTCTTCA 6420 GAAGAGATTT GCATTTGAAT TGGTGAACTA AGTAAAGCAG AGGGCCCTGT CTAGTAGGGG 6480 TAGGCATCAT CCAGTCTGTT GAGGACTTGA ATAGAACAAA AGGCAGGGGA AGGTTGGAAT 6540 TGCCCCCTCT CTGCTTGAGC TGAGACATCT ATCCTGCCCT TGGCACTCCT GGTTCTCAGG 6600 GGTTCAGACC TGGATTCCTG GTCTCCACCT TGCCCATGGC AGACTGTGGG ACTTCTCAGC 6660 CTCCTATCTA ATTAATAAAT TTTTTTTTAC ACACACACAC ACACACACAC ACACACACAC 6720 ACACACACAC ACACACCCTA TGTATCCTTC TGTTTTTCTG CAGAACCATA TTTAATACAC 6780 CTGCTTTTAT GACGATTACC TATCGATTCT GTATTCTGCC AAAACTGAAA ACAGTTCATT 6840 TTTCCATCTC TTCTCAGAGA GGCTTGTCAG CCATTAGTTC TCTGATGGGC TCAAGAAGTT 6900 ATGCAGTTTT TTTTTTCTCA CTGTTAGGAT GGAATTGATA TTCTGTTGAA ACTTTCTATA 6960 CCTAAGTGGA AACTTGTTTT GAGGTTATTT TCTCTACTTA CTTTTGCTGG AAATGGAACA 7020 CTCTGTATCT AGTTAAGACA CATAAACTGA CTTGTGATAC CATAATGTTG TGTTGAATTT 7080 TATATTCTTA GAAAATCATC TGTCAAGGTG TTAACTAATG GCAAAGCATT TAATAAATCA 7140 GCATTCATGT ATTCAGGTGC TCTGAATTAT CTGACTTTTA AATTCTTACT TTATAAATGA 7200 GAAAATTGGG GCATGGAAAA GTTAACTCTC CTAACCCCGA ATTATTACAT TATTAAGGAC 7260 AGGACTTAGA GGCCAGATAT CTTAAGTCAT TAATATTCTT TGGCTCACAG AATTGGCAGT 7320 ATAACCTAAA GGTAATAACT AGGTGATTTT CTTTTATATC AATTAAATAT GTCAGTTTTC 7380 AAATATTCAT AAGTACCTAC TGTGCAGGGA AAGAACATGC CATACAAAAG ATGTAGTCCA 7440 GGCCTTTAAG AAACTTTCAT TTAATGGGAA CTCAAGAAGT GTACATATAA GGAGGGAAGT 7500 AGCAGTATGG TACAAGATAA TACATACATA TCAGTGAATG ATATTGCCAA AAAGTGCTAT 7560 TGATAGAGCA ATAATTCATT TCTGCAAACA GCTGCTGATC TCCTACTGAA AACAGAGGAG 7620 GGAGAACAGG ACGCCTCGTG GTCAGGATAG AAGAGAAAGA CCTTGAGTTG AGCCTTGAAC 7680 AGTATTTAAT ATTCAAAAGG TTAAGAGAGG AGAGCAATTG AGGAGGGGAG AATAGTTCCA 7740 GCACAAATGA TGGTGTACAA GATGAACACA GTCAGTAAAG AGCAGACTGG TCTGGATGGA 7800 GAGGAGGATT TGCATCATTT GGGATTACGT CATTTAGACC CTTGAAAGCC AGGATTGAGT 7860 AAAGCCACAG TGAAGCGACT GGCTCGTATG GAAGCTTTAT TTTAAGAAGA TTAATCTGGT 7920 AGTGACATGT GCCAAAAACT GAATAGGTAG AAATGAGATG CAGAGAGCCC AGTTAGAACT 7980 AAGTCTGGTG CAGTAATGCA GGATTGAGGC AATAAACACC AAACTACAGT ATCACCAGAT 8040 AATGGATGTT TGAACGGACG GTTTAAAGGA AAATTGATGG TATTTGGTAA TTTATTAGAT 8100 AATCCAGGGC CATGGAATGA GAGGGGAAAA TGACTAACCA TAGTCATCAA ATGGTTTTTC 8160 TTAATGAATC TGAATTTTGG TGTAAGAGCA ACATTTTCTT AGGCCTTGCC TAGTTGGTAC 8220 AGCTGACTAT GATAATGACT GCTACCATGC TTGTTCCTCT TTTAGCAGCT GTGAGTCCCC 8280 CACCAGCCAA ACAATGAGCC TCTTGAAAAG GACGATGCCT TTTCACTTCT CTCCAAGTGC 8340 TTGGCAAATA GGAGGCCTTT TGAAGTTACT TTATAGTTAG GGGTTCCCAG TGAGTATTTG 8400 AAATATTAAG TCATGCCCGT GGTTGACAGC ATGGCCCTAC TGCTCATCAT CAGCTATTAA 8460 CCTTAGGCAA GTTAATGAAC TTTTCTAAGC CCCAGTCTAC TCATTTATAA AGTGGGATTA 8520 TTAATAATGT CTACTTCATA AAATTATGAA GCCTGAGTTA GGTCATTCAG ATAGTGTTTA 8580 GTCTGATTCT TCGAACCTAG TAAACAGTCA GTAAACAGAA GCAAATGCCA CATGCCTGAT 8640 TTATATCCAA GGGGAGAAAG GTAAAAGTGA AATTTTCATG ATTTATGGAT TCAAATTATA 8700 CATTTCAAAG ATGCTTTATA AGCTATTGTT TTGGTAAGAA GAATTGAGCT GAAACAGAAT 8760 TTTCTGACAG CAGTGATTAT TAAATGGTGA AATAGGCTAT TGATGTCTTT AGAGGATATA 8820 GATGTTCACC TTTTGCATAT AAGTGCACAA AAATTCACTA AGTAGATATG TCTGTCTACA 8880 CAGAGAGAGA GAGCGTGAGA GCATTAAAGT TAGTAAACAT CCCCCTCGCT TTTTTTTTTT 8940 TGAGACAGGG TCTTACTCTG TTGCCTAGGC TGGAGTGCAG TGGTGCAATC GTGGCTCACT 9000 GCAGTCTCAA CATCCTGGGC TCAAGCGATC CTCTCGCTCA GCCTCCTGAG TAGCTGAGGT 9060 GTGCACCACC ACACCCGGCT AATTTTTAAA TTTTTTTATT GTAAAGGTGA GGTTTCACCA 9120 TGTTGCCCAG GTCTCAAACT CCTGAGCTCA AGCAATCTGC TCACTTCAGC CTCCAAAAAT 9180 GCTGGGATTA CAGGCGTGAG CCACCACGCC TGGCCAGTAA ACCCCATTCA TTTACATCAT 9240 CTTACTTGTC CCTCCAAAAT CCTGCAAAGT AGGTAGGTTC TGTCTTTATT TGTTATTTAG 9300 GTGAAGAACT TGAAGTGGTG TTGAGGAATA GGTGTTTTGC CAAGAGTCAC GCAGCTGGAG 9360 TGGCAGAGCT GTATACTCTT CTGATTCCAC CAACGCTGTT TACATCACAT CTGGAGAAAA 9420 GTGCTCTGAG GCACAGATGT TTAGTGGGAG GGATGAGACA CAGGCTGCAA TGCCTAAAGA 9480 TAATCGGGAA TAAAAGCAGA AAACAAGACG TTTGTTTCTG TTAAAATGAG ACAGAAAATA 9540 AGGCGTTTGT TGTTTGGGAT TGAGCACTTG GAGAAGTGGG GAGCGATTTG ATTTGGGTGA 9600 GACTGCTCCT GGAATGCTGC ATCTGGTTCT GGACTACTCA TTACTAGGCT TATAGAAACT 9660 AGCTGGAGGA GGTTCAAAGA AAAGCTCCAA AATGATTAGC GGGCTGACGG GATTGATTTA 9720 TAAGAAATAT TAAAAGAATT AAATGTGTAT AGCTCAGCTA AGCAAAGATG AAAGAGACCA 9780 GCTAAATGTA TACAAATATC TGAAACGTGC AAACTTTAAA AAGAGAGATT AATTATTTAA 9840 CATGATACAC GGGGGCACAA TATGCAGTCA CAGGATGAAA ATTTCAGCTG AGTATCTAGA 9900 AGAATTCCCC GATAGTGAAT CTGTTAAGGC TGTCTGTAGT GTGGCCTTTC CCTGGAGAGG 9960 CAATAGAAAT TTCAAGTCTT ACGATTTTAA AAGTTTCTTG GGAACTAGGT ATTAGATGAT 10020 GTTAGAGAAT TATTATTAAT TTGGTCAGGT ATGATAATGG TATTGTAGTT CTATAAGAAA 10080 AATTGTATTT TTTAGAGTTA CATACCCTGA AATATAAGCA TAGAATATGA TGTAGGAGAT 10140 TTGCTTTAAA ATACCACAGT AAGGAAAGAA AGGAAGGAGG AAGAAAAGAA AGGAAGGGGA 10200 AGAAAGGGAA AAAGAGGCAA AGAAGGAAGA GAAGGTAAGA GAAAGAAAAA GAATGAAGGA 10260 AGAAGGCTGG GCACTGTGGC TCATGCCTAT AATCCCAGCA TTTAGGAGGC CAAGTTGGGA 10320 GGATCACTTA ATTAAGCCCA GGAGTTCAAG GCTGCAGTGA GCTGTGATTG CGCCACTGCA 10380 CTCCAGCCTG GGTGGCAGAG TGAAGCCCTG TCTCTAAAA AAAAAAATAA GTTAAAAAGA 10440 AAGAAAAGGA TAGATGAAGT ATGGCAAGAT GTTGGTAATG TTGAACCTGA AGGAAGTTAA 10500 TATGTGAGTT CACTTTCCTC TTCAGTCTTC TTTATGTATG TTTGCCAACT TTCATAATAA 10560 ACAATTTAAA TTATATTTTC CTGATCAAAA CTTAGTAGCA GTATTAATCC CTGGGCTTCC 10620 TGACTAGAAC AGCCTCATTA CCACATGGGC AGAGTTCTGG CCGACCAGGG ACCACGTAGT 10680 GGTTCACCAT CTTGCTCTGG TAATGTGGTC TGGGCTGAAG GGCCCTTTCT AAGGTTGTAG 10740 ATAGAAATCC AGGAAACTTG TTAGAACTGC AGACCTATCA GGGTACCTGC AGGAGGTGAG 10800 TCTACTAAGG TGAAAAAGCA GAGGGCAGAG GTCGTGATTA GCAGCTGACC GCCCCCTGCT 10860 TTTCTGTCCC TCATTCGTGG AAAATTGAGT GGAGCTCAAT TTTGAGTGGA GCTCTAAGTA 10920 GCTCCACTTG TAGACATTGA GTGGAGCTCT AAGTGTCTTC AGAATAGCAA AACACTAGTT 10980 TTCTTTTTCT TTTCTTTTTT TTTTTTTGGG AGACAGAGTC TTGGTCTGTC CCCCAGGCTG 11040 GAGTGCAATG GCACGATCTC CGCTCACTGA ACTCTGCCTC CCGGGTTCAA GCGACTCTCC 11100 TGCCTCAGCC TCCCGAGTAG CTGGGATTAC AGGTGCCCAC CACCACGCCC AGCTAATTTT 11160 CCTATTTTTA GTAGAGATGA GGTTTCACCG TGTTGGCCAG GCTGGTCTCA AACTCCTGGC 11220 CTCAAGTGAT CCGCCTGCCT TGGCCTCCCA AAGTCCTGGG ATTACAGGTG TGAGCCACCA 11280 CACCCAGCTG CAAAACCCTA TTTTTCTTGA ATGGAGAAAC ACTTTCCCCT TATTTATTGA 11340 GTTTGGGAAG CAAGAAGAGG GGTAATTCAT TAAGTGAAAA TTTCCAAAAT CCAGAAAACA 11400 TCGATAAAGC AGCAGCTTAA TTTTTTTAAG GAAGAATTTT TTAAACTATC TTCTTTTGAG 11460 CCTCTTTAGG AAGACCTCAC GTCCTTGCCT TGAATGTTGA GAGTGGGAAA TCCAGGGAGG 11520 TTTTGGAATG CATGCCTTAT GTCTGCTTTT TTGTTTGTTA GAGAAATATA AATATTTTAT 11580 CTAGGTTTTG CTGATGGCAG TCAAGCATGA ACACAACCCA CTGTTTGAGA AGCTGTAATT 11640 TCTGAATTTC TGCAGAGTGC ACATCTAGGC CAGCAAATGG CAGTAAGAGT GAGGTGGATT 11700 TAGCTCAGTG TAAGGATGAA CTCCAGAACC ATCGGCTCTG ACTGAAAGTG AAGCGGCAGC 11760 CGCGTTGTGG GAAAGCTGGC TGGAGTCTCT CTCATAAGCA GGCATTCTTT TTCTCCAGCC 11820 CGTCACTGTG TTGGTTTGGG CCCACGGTAA GCCTCCTGGC CTCTAGGCTG TAACCCCCAC 11880 CATCCTCCTC TGCCTCGCCT CCAGAGTGAT TGTTCTGAAG CACAACTGGA TGTCATTCCC 11940 CTTCCTGAAC TCCTAGCACC TACAGGGACT CCATCCCTTG TGCCCCACAT ACCTCACACG 12000 TAGACATTCC TAATGAAGAT TTGATTGAAT TATTGTAAAC TCAGTGCCTC CCACTCTTCT 12060 AGTTGCCTCT CTGCCTGCCT TTGTACATTT ATTTATTTAT TTATTTATTT ATTTATTTAT 12120 GAGACAGAGT CTTACTGTAT CACCCAGGCT GGAGTTTAGT GGCACCATCT CAGCTCACTG 12180 CAACCTCTAC CTCCCAGACT CAAGCAATCC TCCCACCTCA GCCTCCCGAG GAGCTGGGAC 12240 CATAGGCACG TGCCACTATG CCCGGTTAAT TTATTGTAAT TTTTGTAGAG ATGGGGTTTC 12300 ATCGTGTTGC CCAGGCTAGT CTTGAACTCC TGGACTCAGG CGATTCGCCC GTCTCAGTCT 12360 CCCAAAGTGC TGGGATTATA GGCGTGAGCC ACCATGCCCA GCCGCTAGCA CTCATCTTAA 12420 TCGTATATTT ACTTATCTGG CTTTCCCACC AGACTGCGGG CTCTTCAAGA GTAAATGCCA 12480 TGTTTTCACC TTTATTTCCC CAGTTTGTGG CACATTCTAG GCACTCGCCA TCATGAAATA 12540 AACCTCTGGA GCTGTGATAT TACAAACGTG AAAAGATGAC GAGCACTCAG CAACTTTCAG 12600 TGAGTAAACA AAGGCTTTCA TTCAGCATGT ATTTATTGAC TGCCCTGATC TGGGCTGCTT 12660 CCTGTCTGTG GTTCAAGGAG AGCATAGTCT ACAGAACCAG AGACCTGGCT ACTCTGGAAG 12720 TTAGACTTAA GCCCACCCCG GTCCTTGAAT GGGGAAATAT TTCCCTTCAT TCCTGTGTTT 12780 TAGGGACAGA AAGATGAGTA ATGCAGTGAT ACATGCTGGA AATGTTTATT CCACTACCCG 12840 AAGCTGCCTC TCAACTTAAC AATCCATGAA AGAAACAAGA TGGTATATAA CTTTTTCTAA 12900 TTTGTGATGC CTTTGTTTAT TTGTTTCCGG TTAAAAGAGG AGGTGGCATT GAATTGTTTG 12960 TTTGGTTTGG TTTCTTCTTC AATAAGAAGC ATCTTAATAT AACTAGACTG GACATCTGTC 13020 CCATTTTCAA AAATTACAAG TTTCGATCAT TGCTAAATTG TACAGATCCC AATCTGTCTG 13080 CTCTGCATAC ATTTGCATTT ATAAAAGCAG AAGCAGACTA GCAGTCTTTC TAATGCAATC 13140 CCCCAAATGC ATGAAGTATT AGATTGCTTC TCCCTATTGG TTCATGCATT GCTAAAGGCT 13200 TAAAAGGATC ATTGATTTTA ATTATTTAAT GTGTACAGCA GGCTGAGCTT CCTTTCTTTT 13260 TTAAGGGAAG AACCTTCAGG GGCATTGCTT TAGTTTTTTA ATGTTAAATC TCATTTTTCT 13320 TTGAAAATAA GAAGTTAAAG CTGTATTCAC ACAAGCTCTC AAAGTGCCAG ATTTTCATTG 13380 TGTTTTTAAA CCATCTAGGA AATGTTTGAT TCTAATGAAA CATTACTGCT GAAAATTGGG 13440 CTGAAATTGC TGGGCTGAAA ATATTGTTAT AACTTCACAT GATTCCAGTG TTGTATTATT 13500 ATTTTTTCTT TTCCTTTTTT TGACCCGATA TAGATGAAGC GAAGAGACAA GGGAGCAATC 13560 CCATGTGTAA TAAAAAAAGG CAGCCTGAAT TGTTGTTGCT GTTTTTGAAA TTTAAGCTGG 13620 TTTTCAATTA AATTCAGTAA ATGGTCCAGG ACTATAAATG TTGAACATTT TTTACCGTGT 13680 GATTTAAAAT TTAGTTTTAA TGTTTTTTTT TTGGGTTTTT TTTTTTTTGA TGGTTTACAT 13740 TTTCCCCATG GAAAGCAGCT ATGTCATGTC GGCATGATTC ATCATGGTAA CATCTCGGGT 13800 TATTTTGGTT TGTGTTATGT TCAGAAAGCG GAATGCCAAA AATAAAGAGT GGTTTGTGAT 13860 GTCTAGTGTG TCTTCCTTTA ACAAATCAAA GGCTTTTATT TAATCCACTT AATGGGACAC 13920 TGCAGAAATT TAAAAAATGG AAGTCCCATC CACAGAAGGC AGGTACTATG ATGTAAAAAG 13980 TTTAGGTGGG GGATTAATAG AGTGATCATA TAATTTATGA GCTAAACCGG AGGCACTTTT 14040 TTTTTTGAGA TCGAGTCTCA CTGTTGCCTA GGCTGGAGTG CAGTGACGTG ATCACAGCTC 14100 ACTGCAACCT CCGCCTCCCG GGTTCAAGCG ATTCTCATGC CTCAGCCTCC TGAGTAGCTG 14160 GGACTATAGG CGCCCACCAC CATGCCCAGC TAATTTTTGT GTTTTTTGTA GAGATGGGGT 14220 TTCACCATGT TGGCCAGGCT TGTCTCAAAC TCCTGACCTC AGGTGATCCG CCCACCTCGA 14280 CCTCCTAAAC TGCTGGGATT ACAGGCGTAA GCCACCATGC CTGGCCCAGA GACACTTTTG 14340 AGAGTGAAGA GGAAGCTGAG AATAATTCAC TGATCTACAA CTGGGACCAT CCAGGGCAAG 14400 CCAGATGCCA TTACCACTAG CTAGAAAGCT TGCCAAGGTC TCATTTACCT TGGTATATAG 14460 CAAATTCTTC TTTGAATTCT GGAAATTCTG GTAAGTCATT GAGGTAGCTC TGTGCCAAGG 14520 AGCAATATGG TAGAATTCTA ATATTTCAGG CAGTACAACA CTTTCCTGCA TTTGTAGCAG 14580 GTAAAGGGAG GTCAGGGCAG AAGACAAAAC CACTGGGACT CGACAAAGGG CATAAACGTC 14640 TAATGCACCT GATGTAGCTG ATGGTAAATT GTTATCAGCT AAAGATCTTT CATAATAAAT 14700 AAACTTATCA TTTGTAGGAG GGCACAGAAA TCGTGGAAAG CTGGGATTCA GGTTGCCTGT 14760 GGCTTTAATT CTGGAATCAG AAATATTAGT CAAGGATATC AGTCTATGAA GTAAGTTTTC 14820 AATGTTATAT GCCACAAGAT GCAGCTGTCC TATTTTCACT TCCAGTAATT CCTTCTGAAT 14880 TAATACACCT TAAAAATAGC TGCAGCTTCT CAAATCTGTG AGAATCGTAT GTGCTGCTTG 14940 CTACACTTTC CTTTTTCCTG AAGGCCTCTT TGAGGTCTTT CAAGAACTCA ATTCAATTCA 15000 GCAACAATTA GGGGGTCTAA GGTATACAGA CGCTGTGCAA GATGCTCCTG AGACACAAAG 15060 AGGAGGTCAA GCCCCTGCCT TCAGGCACCT CTCTATAATA TAGGAGGAGA AAGAGAAGAA 15120 ACACTAATAC ACATAGGTAG GTGCCATTAA AAGGGTGCAT ACATTAAAGC CAGGTGGTAG 15180 GTGCAAGAAG ATTTGTAACG TGAGAATTTT CTGCATGTTT GAAATATCTT ATAATTTTTA 15240 AAAATTAAAA TGGGAGATAC ATATATATGT ATTTATGTAT GTATATATGT ATGTACATAT 15300 ACACACATAT ATACATAAAT ATATACATAA ATATGTATAT ATGTGTATAT AGACATAAAT 15360 ATGTATATAT GTGTATATAT ACATAAATAT GTATATATGT GTATATAGAC ATAAATATGT 15420 ATATATGTGT ATATAGACAT AAATATGTAT ATATGTGTAT ATAGACATAA ATATGTATAT 15480 GTGTATATAG ACATAAATAT GTATATATGT GTATATAGAC ATAAATATGT ATATATGTGT 15540 ATATAGACAT AAATATGTAT ATATGTGTAT ATAGACATAA ATATGTATAT ATGTGTATAT 15600 AGACATAAAT ATGTATATAT GTGTATATAG ACATAAATAT GTATATATGT GTATATAGAC 15660 ATAAATATGT ATATATGTGT ATATAGACAT AAATATGTAT ATATGTGTAT ATAGACATAA 15720 ATATGTATAT GTGTGTATAT AGACATAAAT ATGTATATAT GTGTGTATAT AGACATAAAT 15780 ATGTATATAT GTGTGTATAT AATAATGTGT GTACATATAC ACACATATAT ACATACATAA 15840 ACATTCTGCA TTATACCATT CACTTTGTAA CCCATCTTCC CTAAAAACTG TCTCATAAAG 15900 AGTCTTCTTT TCCCTGTACC TATGCAATGG TAAGTAGCAA AACACACATT CTTTTGGGTC 15960 CCCATAACAT TCCCTGTAGT TTGCCCTTAA CAGTCTTTGA TGTGAAATTT ACTGTTTCTG 16020 TCTTAACCTT GCCTGTCTCG CGTACATGGA GTTTTGGCTC CTGGCTCCTA GTCTGCATCT 16080 TCACCCCATC CCTTGCCCAA AGAATCTGGT TATGTGACCA CTGCTCATCT TTTCTGCTGT 16140 CACAACTCCA GTCCAAGCCA CAAACCTCTC TCTCCTGGAC TCCTGCGGGG AGTTCCTTTC 16200 TCTCCCTGCA TGAGTCTATT CTCCGCACAA CTGGCAGAGG TAAGTGAGAC TGCGGAAGAG 16260 GCAAGTTTGC AAGTCCAGAG GAAATGAAGA CTCTGCTTGT GCACATGCTG GGTTTGACGG 16320 GTGCTGGATA TCCGATGGAT GGCCCTTAAG GTGAGCTCAA GGCTTAAGGG AGAGATAGGG 16380 GCTGATGATC TGAGATTCAT CAGTGTGTGG CTGATGTTTA AACCCAGGGG ACAGGATAAG 16440 AAGGTTATTC CAGGGAGAGC GTAGATAAAG AAGCTAAATG GCTTCTGGGT CCTTAGTCAT 16500 TCAAAATCGG ACCTCTGAGG CAGGAGGAAA GCCCAGAAAG AGTAGATTCC TGGGACTCAC 16560 GGGATAAAGA CTTTCAAAAA GTGGGGGCTG GCCAGTGCTG CTGAAGGAAG TAGCAGGACC 16620 GGAACAGAAG GGTAATCGTT GGACCTGGAG AACTTGAATT TGAATTTTAA GGTTGGTAAC 16680 CTTAAAAAAG AGCAATTTTA GATACCTTTT GAAATTATTT GCAAGATTTG TTTGGTATAT 16740 GTGTTATTCC AGGCAAAGGG ACCAGAAAAG TAAAAAATAC TTACTGAACA GTTACTGCAT 16800 GCCTGGCACT GTAACACCCT GTTTAATTCT CACGGCAACC CTATAGAGTA GGTGTCATCA 16860 TCCCCATCTT ACAGATGAGG ATATGAGGTG CAGCTAGATT AAGCAGTTTG CCTCAGGTTA 16920 CACCAACTGG TTAACGTAGA GCTAGGATTT GAACCCGGAT GGGCTGATCC CAGAGCTCAT 16980 GCTTTAAATC GCTAGACTGG TGCTCACAGA AGACTGGGAC CGAAAAAAAT TAATAAAAAA 17040 AATAAGGAGC CCCCTGGGCT AGCAAATTAG GAGTTGTTCA GACAGATGTG AAAAGGAAAG 17100 CAAGGCAGAG GGAAAGTCAC TGTACAGAAG AGAGAGACCC ATGACAGCAG AGACAGTGAG 17160 CTGGTAAAGT GGCTGGCGAT CTAGCCCCTG AAAATACCTC CAGAGAGGCA GGCTCACGCC 17220 TGTAATCCCA GCACTTTGGG AGGCCGAGGT GGGCAGATCA CCTGAGGTCA GGAGTTTGAG 17280 ACCAGCCTGG CCAATGGCGA AATCCCGTCT CTACTAAAAA TACAAAAATT AGCCGAGCAT 17340 GGTGACAGGC ACCTGTAATC CCAGCTGTTC AGTTGGCTGA GTCAGGAGAA TAGCCTGGAT 17400 CCGGGAAGTG GAGGTTGTAG TAAGCCAAGA TTGCGCCACT GCATGCCAGC CTGGGCGACA 17460 GAGCAAGACT TTTCTTAAAA CAAACAAACA AAAAAGAAAA AAGAAAAGGA AAGAAGAAAG 17520 AGACAAAGAA AGAAAGAGAG AAGGAAAGAA AGGAAGGAAG GAAGAGAAGG AAGGAAGGAA 17580 AGAAAGAAAA GGAAAGAAAG AAAAAGAAAG AAGAAAGAAA GGAAAGAAAA GAAAGAAAAA 17640 GAAAGAAAGA AAATACCTCC AGAGAGCCAG GTCTCTTAGG CCTTCTGAGA AACTCACATC 17700 CCTTTTGATG AACACAAATG CTTCACACTC TCAATGTTAT TGGTAATCCA AGTTATCAAT 17760 ATACCTAAAT CACTTAGTAC TGAATCTGGC ATATAGTAAT CACCTAATGA AGAGATAAGA 17820 GTCATGGAGT ATTCTGAAGC AATTAGAATC AATAGACTCA ATATACACAT GGCAACAAAG 17880 TTGGATCTTA AAAACCGACC TGAGTGAAAA AGGAAAGGGA AAGATACATA ACACGGTACC 17940 ATTATGTAAA TTGATAATAT ATGCTTACAC AATTTGTAAG AACACATACA AATAGATACA 18000 TGTATATTAA ACATACTCGA ACGGTTACCC TATGGGGTGG TGGCTGGAGT GGGGGTAAGT 18060 CCGTAAGCTG TAATGGAACC TAAACAAATA CATGAAACGA GTAGGAATCA GAAGGAGTAA 18120 CAATAAAAAT GTGCCATGAA CTGAGGAGTG TAAATTAATC AACTCACTGC ATCTGAGGTT 18180 AAAAATAGAA AGATGATAAT TGTTATTCTT ATTACTCCTA GGTCTTCCAC TTGCACTCAG 18240 CTTTACAATG TTGGACTATC CTTCAGATGG CACCCTCCTT GCACTTGCTC AGGCAGGAGA 18300 GCTTTTTCCT CCAGCTTTCT AGGTGATTTA ATATATCAGG GAATAAGTAT AAAAAAAGGC 18360 ACGGTGCTCC CTGGGTAGCC TTTCTGGACT TCAGAGCTAA ATTGCAAAGT CAGTTTTACA 18420 CATGTGATTT CATCTATGAA ATTAGGGCAA GGTATAAAAC TGGCACAGAA AAAATGTGAT 18480 TTATTATGGT GTTACTATCC CTTACAAGCG GAGTGTCAGC TGCCTCTTTT TGTCCACTGA 18540 TTTAAGGCAA GATGAACTGA AAGTGGCTAT GATCACGTCT TCAAAAGCAC ACTCTGGCCC 18600 CTCGGCTGCA GGCGCCCTGC ACATTCCCCA GCTGCGTGTC CGGTGGTGAC ACAGTGCATA 18660 ATTGTGGCGC CTTCCTGGTG CAAACTGTCT CACTTAGCTC CGTCTTGCTG GCACAGCAGA 18720 AAGGAAGAAA TCGAAAATGT TTGGATTTCA AAGGTAACAA GAAGCTGGAA AACAACTACT 18780 GGCCGAGTCT GAGAGTTTCA GCGGAGACTG GTGCAGCCTT GTGTTTTTCC ACTGACAGCT 18840 GAAAATGAGC CCAGCTTCAG TGAAGCTTGT TTCCTTCCCT CCTCAAGGTT ACCCACAATT 18900 CTCAGTTCTC TCAGGAAAGC CAAAAAATGA ATTTGAGGGT TTAGGATTGT GGTTCTTTTA 18960 TCTATTACAG GATTGATAAT ATGTTCCTCC ACCAGATGTT CTGCTTGTAA CAATACTCAC 19020 TTCCTGACAC TACTGCATAT GCAGGAGTGT CACTACCAAG GTAAACACAG AATTGGCTGC 19080 CCAATTCCAA ATCCCTGAAC TGAGTGAGAG AAATCAGAAT TATAATAGGG GATTCAACAG 19140 AGCTGGCTAC GGATGTGCCA GTGGTCAGAT ACTTTGCTCA TCATACGCAG GTGCTGCTGC 19200 TCTAGCAACT GCTCACTGCT TCATTTCCTG CCTTGGTCTT TAAATACTGC TTTTCTCAGC 19260 TCAATTGGCT TTCTTCCCTC TGGCAGTCAC GTTTCTTTGG GTCAAACAGC AAATGATTCT 19320 TTAGAATCAC CTGGTACTCA AAGGAGCTAC AAGACATTGG GCATCCACTT CCACTCTCTT 19380 GGAAAAACAA TTTTATGGAA GCCAAGGTTG CCATAGTGCC TCTTGAGGTT GTTTGCTCAG 19440 CCAAGGCCCA AGCTTTGTGC TTCAAACATG AAATTAGAGA GCTTCAGAAC AAGATCCACA 19500 TTTTCAATGG CCTCACCCAA CTGGATAAAA GAACAATTGC CATATCTCAA TGACCACCTT 19560 TTCTCAGGTG GGATGGTAGA TGCTGGAATG GGTCACAGCA TTGCCCAACC AAACTTTGCA 19620 AAAAAGGCTG GAAGCTCTGA CTGGGGACCC TAAATATGCA AAAGTTAATA GGCTCTTCAT 19680 GCAGAATATG AACCCCGTGT ATGGATATAG CTAAAGGGTT GGCCTTTATG TTTCTATTCC 19740 TTCACAAACC TGGTAGAATA GATATGCTTG TTTCCCTTTA AAAAATGTCA ACAATTGCAT 19800 TTATGATGCT GTGTATAGTA ACTCACAGAT CATGCTCCAT GAAAATGCTT CAGAACCCAA 19860 TATAAGGAGA TTTTTTAGCC ATGTGTGACA AAAGAGAGGC CATTTCAGTG TTGAAATTGT 19920 TCAGAGAAGT ATTTGATTAT GTTTTCTCAG ATCTTTTTAT TTTTATTTTT TTTGAAACAG 19980 AGTCTCACTT TGTCACCCAG GCTGGAGTAC AGTGGCTGTG GTCTCGGCTC ACTGCAACCT 20040 CTGCCTCCCA GGTTCAAGCG ATTCTCCTGT CAGCTTCCCG AATAGCTGGG ATTACAGGCG 20100 CATGCACCAC CATGCCTAAT TTTTGTATTT TTAGTAGAGA CAGAGTTTCG CCATGTTGAC 20160 CAGGCTTGCC TTGAACTCCT GACTTCAGGT GATCCACCCA CCTCAGCCTC CCAAAGCACT 20220 GGGATTACAG GCATGAGCCA CCGTGCCCAG CCTGTTTTCT CAGATCCTGT ATTTTGTTTC 20280 TGAAGCCTTC ATTTCTATCT TCTTATTCAT TTTGGAAGTA GTACACCTAA GTAAGGTTTT 20340 TAACAATCAA ATATCTTTGG AAAATTCCCT GGTTCCTTTC TTATTCCTAC AAAAATATGT 20400 TCAGTATAGC TGATGTTATG TTTCTTTCAA ATTATTCATT TCTCTATCTC AGAATTTATC 20460 TCATGCCTAA TTGTTATTGA ATAGTCTTCA CTTCTTGTCA TCCAGTTTCT GGTCTCTTAT 20520 TTCACTCTAA GTCTAATTGG CTATTAGAAT AAAGAGCTTG TAACAGATTC TTTCTCCAAT 20580 ATGTCTTATC TTTTGACTGC ATGCCAGTGA CAAACTGTTA ACTGTTTTGA TTCTTCATAA 20640 CATTCCACAG AACATGCTGA CTCCTCTCTT CCTGAAAGCA ATGCCCAAGC ACAGCATTGT 20700 TAGATAGTAT GTACGCAACA GGGACATGGG TGCATAGCAA AAACTAGAAG GAAGGAGGAC 20760 CTTCCTTAGC AATGGGTGAT ATGGTCCCTG GACTTAGACT CCAAAGGGTC GTGAGGTGAA 20820 ACACACATCG TCCATACCCA GGAAGCACAC AGGTGGGATG GAAGAGCTGT GCCTAATGAA 20880 ACTTCATCCA CGTGGAGGTG GAGGAGGCTG CAGCTGCAAG AACTCAGAGC TGCCTTACCC 20940 AGACCAGGGA CCAGGGAGGG CTTTCTGGAG GAAACAGCCT CTGAACTGCC AGCTGATAGA 21000 GGAGCTCTAC CTCAACTCTT CTGGTTCCCC AGGGCTGCTT TTCCACGTCC ATTTATTGGC 21060 ACTGAAGTTT GAATACCTTC AGGGGCCCGA AAGCCTGCCA GGTCCTCTTC TCTGCAGAGC 21120 AATCACACCA ACCTGCAAAG GGCTAGGAAA GGGCTGTCAT CATCTCCTAC TCAGAAACTG 21180 GTTCACTGGA AGGACTCAGG GGCCACTGAA TACATCCTGG CAGCTTTCAC AAGAAGGGCT 21240 TCTGACTCAA GGATGTTTCC ATCTTTGCCA GGTCGCCTTT TCTCCTTCTC TTAGAGTTTG 21300 GAGGACGCAA ATGTGCTGAG AAGTCAACCT TTCCTGCAAG GTGAGACACA AGGGCCTTTC 21360 CCAGCAGAAA GAAGAGAGCA AATGGAAGGT CCTTCTTCCT CCAGTAGAGG ATGGACTCTG 21420 TCTGGCAGCC ACCCAACAGG AAAAGCACAA TGCATGCCTG CCTGCTTCCC TCCCTCCCTC 21480 CGTTTCTCCC TCCCTCCCTC CTTCCTCCCT TCCATTCTCT TCCCTTCCCC TCCCTTCCCT 21540 TCCCCTCCCT TCCCTTCCCC TCCCCTCCCC TTCCCTTCTC CCTCTCCTTC CCTTCCTCTT 21600 CCCTTCCTTC CTCTTCCCTT CCTTTCCCCT CCCCTTCCTT TCCCTTCCTC CCTCCCTTCC 21660 TCCCTTCTTT CCTTCCCTTC TTTCCTTCCT CATTTCCTCC CTTCCTTCCT TCCTTCCTTC 21720 CTTTCTTCCT ACTTTCCTAC CTTTAGGGCT CTGTGTCTTT GGAGTCCATT CTGATTATGC 21780 TGTAATGTCT GCCCCTTCCT CTTCTCTGTC AAAAAATGAA AGACATGGAA GCCACTTGCC 21840 TTTTACTGAA TTAAAAATTA GTAAAAGAGC TAAAAATTAA TGGTTAAATA TGTACGCATA 21900 AATTATGCAG TATACTAACC AATGAAAAGA TACACTTCTC TTAATTAAAA GCTGACAGGG 21960 AGGGAAACAA GAAAAGAGAA ACACAAAACA ATAATCTAAA TGACCTATTA GTTGGAAGAA 22020 CAACATCAGA GAAAATAGAT ACTGTGTATA GTCATGTGTA TGTCTATGGA ATAACATTTG 22080 TAGAGAAATC TGGACTGATC CTTTCTGAGT AAAGAGAGCT GTGGGTACAA TTAAGGGGAG 22140 ATTGAAAGGA ATCCAAAAGC ATAGCAGATG CTGTGCCTCA CTGGAATGGT TGCCGATCTC 22200 CTCCAAACTA TGAAGTGTTT GAGGCTCAAC TTTAATATAA TTAAGATACA AAGACAGAAT 22260 GAGAGAAAGA GAGAAGGGAG CTCACTGGAA GAACACTCAA GATTCCTTAC TACTCATTCT 22320 CTAAAATTAC AATTGTTCTA GATGGAAAAG AAAAAAAGCT TCTCTGTTAA AAAAGGAGCT 22380 TGTGCTATAG GAGGTTTAAA ATATACTTCT GACCCATCTC CAACATTCTA AATCCTTCCC 22440 AGAAAAGTAT GCCAATCCCA AGAAATATTC AATCAAATTG CTGGAAAGAA AAATACAAAA 22500 TATTAAAATG TATTAGGAAG CGACAGTAAT TAAATCAGAA CTGGAGCAGG AATAGACCAG 22560 CAGATCAATG AGACAGACAT CAAGTCCCGG AATGTGGACT TGCAAATGCA TTAAGTAATA 22620 TGATATGCAA TAAAGGTGGC ACAGTGAACC AATGGGAAAA AAATTAATCT TATAATAATT 22680 GATATTGCAA TAATTGTCTA GTAATTGGGG GAAGAAATAA GCTTATTCCT TATCTCATTT 22740 CTTTTTTTCT TTTTGAGACA GAGTCTCACT CTGGTAGCCC AGGCTGGAGT GCAGCGATGC 22800 GATCTCTGCC CACTGCAACC TTGCTCTCCC GGGCTCAGGC GATTCTCCCA CCTCAGCCTC 22860 CCGAGCAGCT GAACTACAGG CGTGTGCCAC CACTCCCGGC AATTTTTTTT TCCATTTTTA 22920 GTAGAAATGG GGTTTCACCA TGTTGCCTGG GCTGGTCTTG AACTCCTGGG CTCAGGCAAT 22980 CCACCCGCCT TGGCCTCCCA AAGTGCTAGC ATTACAGGCA TGAGCCACCG CGCCTGGCAG 23040 CTCATTTTTT AGACTAAATA AATTGGAGAT GGCTAAAAGA TTTTTATGTA GGCCAACTAT 23100 GTTTTTAAAA AGTTTTTTTT TTTAAGGATA TCTGCTGGAA CCAATCATGC CACCAACCAA 23160 AGATGCAAGA CTATAAAACA TACCCAGTTT TTCAAAGCAT TTAAAAATTA TTCTAAAAAT 23220 ATTTTTTCTC CAGAAATTTT GCATTGATTC CCTGAAGAAG CATTAATATG GGACCTGACT 23280 TATAAAATGA TGAACTCAAT CTCCCCACTC AAGGTAGGAG TCTCTCAGAT TTAAAAAATA 23340 AGCATCCTAG TCCTCTTGTC CCTGTAAAAG TTAACCCTTA CACCTGAAAC ACCAGGAGAC 23400 TGGCGGTTGT TTGCATAGGG GTTACAATTA AAGTTGAGCT ACCTCTGACA TCTATTAACA 23460 CCAAAATTAG TAAACTATGC ATGTATGGAG ACTTTTATGA TTGAACTTGT TTATTGAGTC 23520 AAGAGATATA GTTTACAATG AAAATTTGGG GCATATCAAA ATGACCTTGG CTTAGCTTAG 23580 CATTTGCTGA TGTTAACTAT TTTCTTCATT GGGCTGATTT TAGTTGCTTA GGAAAAATAC 23640 AAACACACAC ACTTTAAAAT TATATTAAAA TCCCGTCCTA AACCTCAGAG TCCAGAACCG 23700 CATCCTAACA CTGGTCATGC ATAATATGTT TAAATTTTTG TGCTTTAAAA ACTACAAATA 23760 AGGAATGTAT TAATAGTTCC ACAATCAATG GTCAGTTAGC CGAGGGAAGA TTAGCATAGT 23820 TAAAGACTTA AAATGGCTTA ACAACATATA TCAAAAGGAC AAAATAAGGG GAACAGAGTC 23880 TAGAAATGAG GAAACTGGGA CACAGGCAAA AAAAAAAAAT GAGAACTGGG ACATGAATAA 23940 CGCAAGGGAT AAGACTAATA CACAAAACAC CCCAAATAAA TAGCCAGCAT TTGCTGAGCT 24000 CTTACTGTGA GCCTGTTCTA AGCACTTTAC ATATATTAAC TCATTTCATC CTCAAGGAAC 24060 CATCTGAGGC AGGCACTGTT ATCATCTCCA TTTTACAGAT AAGGAATAGA CCCAGAGAGG 24120 CTGAGCAACT GGGCCTATTC CACAGCTACT ATGGTGGAGA TGAGATTTAA ATCTAATCAT 24180 TGGCTCCAGA GCCCATGCAC CCAATGGCTG CACTAAGTGA ATGCATGCGC TATCAACGTT 24240 GCCAAAAGTG GGCCACAGCT CGGATCTGCG TTTTCCAGTA GCCAAAGCAG AGAGTGTGAT 24300 CAGACCTCAC TTTAATAAGC AAGTCTCAAG CCAGAGAGAG GTGGTATCAG GCAGCAAACA 24360 GGCTGCTAGT CGAAATCCCA CTTCTTCTCT GAGTGGTCCA TACAGTTTTA CTCTACTTGC 24420 TTACAGAATG AAAATAGCTG GAGTTCAGGT GCGCTTTCAA TGCCCTGTTG TCAGGATTGG 24480 GCTTTTCAAG TTTATTTTTT GTTGTTGTTT TTAATAGACT GTACTTTTTA GAAAATTTTT 24540 AGATTTACAG AAAGATTGAG AGGATAGTAC AGAGAGTTCC CGTATACCTC ACACCCAGTT 24600 TCTGCAATTA TTAACCTCTT ACATTCATGC GGTACATTTG TTACAATTAA TGAGCCAGGG 24660 CCGGCCGGGC ACAGTGGTTC AGGCCCCTAA TCCCAGCACT TTGGGAGGCA GAGGCAAGCG 24720 AATCACTTGA GGTCAGGAGT TCGAGACTAG CCTGACCAAC ATGGTAAACC CTTTCTGTAC 24780 TAAAAATACA AAAAATTAGC CAGGCATGGT GCTGGTTGCC TGTATTCCCA GATACTCAGG 24840 AGGCTGAGGC ACAAGAATTG CTTGAACCAG GGAGGCGGAG GTTGCAGTAA GCCGAGATCG 24900 TGCCACTGCA CTCCAGCCTG GGCAACAGAG CGAGACTCCA TCTCAAAAAA AAAAAAAAAA 24960 AAAAGAAGGA AGGAAGGAAG GAAAATTAAT GAGCCAATAT TGAGACATTA TTATTACTAA 25020 AGTCCATGCT TTATGCAGAT TTTCTTAGTT TTTACCTGCT GTCATTTTTC AGTTCCAGGA 25080 ATGCATTCAG GATGCCATAC CACATTTAGT TCTCATATCT GCTTAGGCTC CTCTTGGCTA 25140 GACTGAGTTT TAATCTACTT TCTGCAGAGC CTGAGAACTT TAGCATAATT TCCTTGAAAT 25200 TACAGCTCAA TATTTTCAAG CACTTATACA AACAGCCTAA TGTTACGTTG GCCCATAACA 25260 GTGTTTCAAG GTAATAAACT TCTTTGTTTT CTGTGCCGAT TGAAAGAACT GCTGCTTAGC 25320 CTCCTGCCAG ATGATGAACT GGGTACACAC GAGCATTTTT CCAGGTAAAG CATATTTCGT 25380 GCGACTTCTT AAGCTGCAGC CTTATATGCA ATAATTGTCC ATTTACAAGA CTTATGTTCG 25440 AATTTCAGGC ACTCTGTTTT CACTAACCAT ATCTTCAACT TTGATAAGTA CTGCTTTAAT 25500 CACTCAGAAA ATTTAACTTG ACTAATTTTT TTTCACCATC AGTTTTTTTT CTGTTGACTC 25560 TTTCTCCTTT TTCTGTTTGC CCAGAAACAT GCTCAGGATT CTCTCAGGCT TTAAAAAATG 25620 AAAAAATGTT TCCTGCAATC TAGTTACTCC TTGATTCTCT TGTTCTGTTT ATCGCTGGAA 25680 TTCTTGAAAG CTTGGTGTAT TAGTCTTTTT TCATGCTGCT GATAAAGATA TACCTGAGAC 25740 TGGATAATTT ATAAAGAAAA AGAGGTTTAA TGGACTCACA GTTCCACGTG GCTGAGGAAG 25800 CCTCACAATC ATGGTGGAAG GCAAAAGGCA TGTCTTACAT GGCAGCAGAC AAGAGAGAAT 25860 GAGAACCAAG GGATTTCCCC TTATAAAACC ATCAGATCTT GTGAGACTTA TTCACTACCA 25920 CAAGAACAAT ATGGGGTAAA CCGCCCCCAT GATTCAATTA TCTCCCACCG GGGCCCTCCC 25980 ACAACACGTG GGAATTATGG GAGCTACAAT TCAAGATGAC ATTTGGGTGG GGACATGGCC 26040 AAACCATATC ACCTGGCCTA TAGCATTATT TCCATTTCTT CCCCATCCTT TTATTCCTCA 26100 AACCGGTACA ACCAGACCTC TTTTTTTTTT TTTCTACCTG AAACTGCTCT TTTGAGGGTA 26160 GCTGATAAGT CCAAAATACT GTCACCTTTT CTCAATTCCG TTCCTTCTTA TGCCTTTGGA 26220 GCAATTGACT GTGTTGGTTG CCCCCTCCTT TAAAGTGTCT CTCACTTGGT TTTTATGACT 26280 AATGATCATG ATTTTCTTTT TCCTCTCTAA ACATTCCGCT ATCTTTTTAG CTTCCCTTCC 26340 CCCTCCCATC CCCTAAATGT CCTTGTTTCC CAGAATCTGC CTCACCTCTT TGACTTCTCT 26400 ATGCCCTGTC ATTCACTCAT GGGTCTTTAT TACATTATTG CATCTGTGTC AATAACTCTG 26460 GTCTTTCTCT TAAGTTCCAG TCTCCCATTT TCAAATGTCC CCAGACATTT CCAATTGAGT 26520 ATCTCTCCAA TGTATTTAAC CTGCTAAATA TCTAACACAT AATCTTTCCC ATCAAATCGT 26580 TTCCTCTTAA GCTTTTCTTA TTTCCTATTA GTACTCCTGC ACTTCTCCCA GGAGCCCAGA 26640 CTTAAAACCT TGAATTTCTC ACCATAACCT CTCTTTTGTC TCCCATAATC AATTAGTAGC 26700 AAGTGTTATC AATGATTACT TGACAATATC TTTTTCTATT TCCCTCCCTG CTATGATCAT 26760 TCATCTAGCA AGAAGAGTTG GCCCTTTGTA TCTGTGGTTT CTGCATCCCT GGATTCAACC 26820 AACTGTAGAT GGAAAATATT TGAAGAAAAA AGCGTCTATA CTGAGTATGA AAAAATTTTA 26880 TTTCTTGTCA TTATTCCCTA AACAATACAG TATAACAACT ACAGCATTTA CACTGTAGCG 26940 TATAGATCTT ATAATCTAGA AATGATTTCA AGTACACCAT TATATATAAG GGACTTGAGC 27000 ATCTGTGAAG TTTGGTATTT GTGGGGCATA CTGGGACCAA TTCCCCCATG GATACAGAGG 27060 GACAACTATA TTTACTCAGT GCTTACTAAA TACCAGTTGG CCAATGTGTT TTTCTTTTTC 27120 TGTTTTCCTG TCTTTAGTTT GCCCCTTGCC AATTAATTCA ATAGTGCTGC CAATGCCAGG 27180 TGTACCTTCA GAATATTCTA TTCTAATTTT GTCATCTCCA AGCTTAAAAA TATTTAATGG 27240 GCCAGGCGCA GTGGCTCACA CTTGTAATCC CAGCATTTTG GGAGGCCAAG GGGGGGTGTA 27300 TCACTTGAGG TCAGGAGTTC CAGACCAGCC TGGCCAACAT GGCGAAACCC TGTCTCTACA 27360 AAAAAGTATA AAAGTTAACC AGGTGCTGGA GCATTTGCCT GTGGTCCCAG CTACTCACGA 27420 GGCTGAGGCA AGAGAATCGC TTTAATCTGG GAGGTGGAGT TTGCAGTGAG CCAAGATCTC 27480 TCCACTGCAC TCCAGCCTGG GTGACACAGC AAGACTCTAT CTCAAAACAA CAATAACAAC 27540 AACAACGAAA AACATTTAAT GGCTGCACCT TGCCTGTGAA AAATGCATTT CTTGGCCAGA 27600 TGTGGTGGCT CAAACCTGTA ATCCCAACAC TTTGGGAAGC TAAGGCCAGG AGTTCGAGAC 27660 GAGCTGGGAT ATATAGGAAG ACACAATCTC TACAAAAAAA AATCCACAAA ATTAGTCAGG 27720 CTTAGTGTTC ATGCCTGTAG TCCCAGGTAC TCAGGAGGCT GAGGCAGGAT TCCTCAAGCC 27780 CAGGAGTTCA AGGCTTCCGT GAGCTATGAT GGCACAACTG CACTCCATCT TGGGTGACAG 27840 AGCAAGGTCC TATCTCTGGA GAAAAAAAAA AAAGAAGGCA TTTCTTAGGA GAGTTCTTCT 27900 CTGTAGAGTC CTAAGGGTTC CATGGAACTC CTTAAAAGCA TCAGAGTATG TGAGTGCAAT 27960 GGGAGGAAGC ATTTAGCCAG AGCAGTTGTG CTCCCATTGC ATATTAATTT TTAAAAAACA 28020 AAGCTATAAA AAAAAGTTGA AAACTACTAC GTTAGCATCA GCCTGACATT TAATGGCCTC 28080 GTAAATCAAA CCTTAATTGA CTTTTTAGCC AGTTATGCTA CTAGCCAACT ACAGACAACA 28140 CACTTTTTAA CCAAATTAGA CTAATAGTTG TCATCAGTGG AAATCAAGTT TGCCATTCTT 28200 CCATGCCTTT GCTCACACCA TTACCTTTTC TGGAATGTCC TGTACTCATC TTCCTGTGTT 28260 GAACTCTATA CCCAACTTTA AAAACCTAGC TCAAAGTTCA ACACTTCCAT TCCATTTCAA 28320 AAAGAGCTTT CCTCTTCCTT AAAGTTTAAG AACTCATTTT CATGAATCTT TTTGGCATTT 28380 ATTGCACACA TGCTTGCTTT GTGTTATTTG TGTTCATGCC TCATATGCCC CCAAGGTGTT 28440 TTAGACTCCT TAACGGCAAA AATGATGCTC TAAACACCTT TCTATCTTTC ATAGTGTCTT 28500 AGTCTGTTTG TGTTGCTATA AAGGAATACC TGAGGCTGGG GAATTTATTT AAAAAAGAGG 28560 TTTATTTGGC TCACAGTTCT GCAGCTATAT AAGAAGCATA GTGTCAGCAT CTGCTTCAGG 28620 TGAGGGCTTC AGGAAGTTTC CACCCATGGT AGAAGGCAAA GGGGAGCAGG CATCACATAT 28680 CAAGAGAGGA GGAAAAAAAG GAAGGAAGAA AGGAGGGTGC CATTCTCTTT CAACAATCAG 28740 TTCTTGTGGG AACTAATGGG ACAAGAGGCT GGGCACGGTG GCTCATGCCT GTAATCCCAG 28800 CCCTTTGGGA GACCAAGGTG GGTGGATCAC CAGAAGTCAG AAGCCTGAGA CCAGCCTGGC 28860 CAATGTGGTG AAACTCCGTC TCTACTAAAG ATACATAAAT TAGATCTAGC TGGGCCTGGT 28920 GGCGTGTACC TGTAGTCCCA GATACTCAGG AGGCTGAGGT AGGATAATCA CTTGAACCCG 28980 GAAGACAGAG GTTGCAGTGA GCTTGTGCCA CTGCACTCCA GCCGGGGCAA CAGAGTGAGA 29040 CGGTCTCAAA AAATTTTAAA AACTTTAAAA ATAATAGAGC AAGAAAGCAC CAAGTTATTC 29100 AGGAGGGATC CACCCCCAAT GACTCAAATA CCTCCCACCA GGCCTCACTT CCAACACTGG 29160 GGATCAATTT CCGTATGAGA TTTGGAGGAG ACAAATATCC AAACTATATC ACATAGTAAT 29220 GAACATAGTA CCTTATCTAT AGAAAGCAAT GGCTAGACAA CTGTTGAATG GCTAACCAAA 29280 TCTGCTTTCC TATGGTCTCG CTCTAGAGGG GGTCAGTATG AGTTTCTGTC AAAAGGAGAA 29340 AAAAAAATGT ATAGTCAGTT TTGTGTGTGT GTGTGTTCAT GTAAAAGAGA TCAAGAGAAA 29400 AGAACAAGAG AAATCATGAA AAGGAGGGGG AATATAAGAA TAATACATAG AAAAAAGCAA 29460 ATTATCTTGT TTATCAGTAA TACCCAAGGG GGTAGAAATG GTAAGTAATA ATCCTTCTTC 29520 ACTTTGTCTG TAGTTCACTT TTTTGCACCT TTATTTTGAT GAATTCACAT CGAAGACATT 29580 AACTCATTAA GGCTTCCAAT ATTTTTGGAG ATAAGAAGGG CTGCTATGCT CTTTATAGAT 29640 GGAAAACTTG GGTCATTAAT AACTCAAACA AGGACATAAC AAAGAAATGG AGCATAAACT 29700 GCCAGGTCCT GACTGTAGAT TTGGATTCCC AGTTGGTGTC TTGTCACCCT TTGTTACTCT 29760 TCCTAAAGTT ATGATCTTTT CTTGTGCATA GGAAATTCAT AGTGATTTCC CATCACCCTT 29820 GGGATTATCA TAGCTCCTTT AAGGTCCCCT CTATGCACTC AATAACATCA ACAGTAAGTG 29880 TTCTTCGAGC ACTTACTGAG TGTATATCAT TGTGTTCTCA CGCAGCACCC ACAGATCTCA 29940 CCAAGAACCT AGCTGAAGCC TGTAGAATGA ATAGGTAAGT ACTGCCATGC CAATCTGGAG 30000 TACTCAAGCG ATGCAAATGA TTCCTTTAAT TGTACTTTTG CAGGCTTGTC AGTTTTGCTC 30060 ATGGAGAAGT GGCTACTGCA TCCATGTTAT ATCTATGTAA TGTTGGACTG CGAAGCATCA 30120 CTTGACTTTT TCCAAGCAGA AATTACAGCT GATGACAAGC TGCTGCTGAG AAAATGGATA 30180 TTTTTCTGAA TTCAGTTCTA CGTGGAAACA GCTGACTAGT TTCCATTGCT GTAAGATGGC 30240 TCTTTTGCTC TTGGTTGATT TTGAGTAATG GCTTTACTTC TGTAGAAAGG AGATTTCATT 30300 TGAAGTCCAC TCAGGGATTT GGTTCAACAA ACTGGAGTAC AGGTTTCAGA AAATATCTCT 30360 TTAATCCTCC AATAATAAAT TTTCTCATCT ATAATTCCTG GAACACTTCA TCCTTTGCAG 30420 CCGAGCATAT AGATAGATTT GTTGCTCACT GTGTTCTGAT TGCCACTTTG ACCTGCTTTT 30480 TCAACTTAGG TTACAAATAG AACAGAATCT CTCTGATTTT TCTCATTAAT TGTTTGAATT 30540 CCCACTTTTC CTCATTAGCA AGAAGTCCAG TATCTTCCTG AGAACTTCCT TTTCTCAATC 30600 TAGGAACTTA CTTGGTCCAT AAGGTAACAG TCTTATTTCT GACTATCAAG GAGAGAAATA 30660 ACAGGAGCCA TTATCATCTT CATGGTGTCA CTTTTGAAAA CTGGTCCTCT GTAGATCTTC 30720 AGATTCTTGC GTTAGTCCAT TCAGCTGCTA TAACAAAATT GCATAGACAG CATGGCTTAT 30780 AAATAACAGA AATGTATTTC TGACAGTTCT GAAGGCTAGA AAGTCAAAGA TTAAGACACT 30840 GGCTGATTTG GTGTCTGGCG AAGGCCCATT TGCTCATAGA TGGACGATGA CCTTTCACTC 30900 TGTCTGCACA TGGCAGAAGG GCAAGAGAGC TCTCTGGGTC TTTTTTATAA GGGCACTAAT 30960 CTCATTTTTG AGGACCCTGC CCCCATGACT TAATCACCTC CCAAAGGCAC TGTCTCCCAA 31020 TACCATCACC TTGAGGGTTA GGATTTCAAC ATATGATTTT GGGGGGACAG AAACACGCAG 31080 TCCATCTCGC TTGTCCACTC CATGGTGGTA TTCTTGCTGG ATCAGTTTCC TCCTTGGGGT 31140 GCATTTGTGT TCCATGTCTA ACTTGCAAGT TATAGCAGGC CCGATAGCAA AGTATTCCAA 31200 TGTTGGTATG CAGAGGCATT GAATAATCAG AATGAACCCA CGCCATAAAC AACTGGTAGA 31260 GCTGCAGAGA GTACCAGCTG ATTATGAGCC CTGGGTAACA GTGGTTTTTA GTTCCTATGT 31320 CCGTCAGCCC TTTTCTCCCA TAGTAGCCCC ACTGTGTTGA AGTGGCTGAA TCGACAGAAG 31380 CTTCCAGCTT GGGCCACATG CTCATGGAAC CAATTCTCCT TATGAGCCGT ACAAGAGCTG 31440 GGTTGCCATT CTGGATACCC TCTTTCTTCA AGAGATTTTA TTTCAAGGAT ATTTTTTCTT 31500 TTATCAACTA CAGGGATTAT TTAGAATCTT AGGGCAGTGG TGCCCAACCT TTTTGGCCCC 31560 AGGGACAGGT TTTGTGGGAG ACAATTTTTC CATGGACCAG TGTCAGGGGG CTGGGAGGCA 31620 TGGTTTTGGG ATGAGTCAAG TACATTACGT TTGTTGTATA CTTTATTTCT ATTATTATTA 31680 TATTGTAATA TATAATGAAA TAATTACACA ACTCACCATA ATGTAGGAAT CAGTGGGGAG 31740 CCCTAAGTTT GTTTTCCTGC AACTAGACAG TCCCATCTGG GGGCAATGGG AGATAGTGAC 31800 AGATCATCAA GCATTAGATT CTCATAAGGA GTGCTCAGCC TAGATCCCCG GCATGTGCAG 31860 TTCACAATAG GATTTGCTCA CCTATGAGAA TCTAATGCCA CTGCTGATCT GACAGGAGGT 31920 GGAGCTCGGG CAGTAATGCG AGGGTTGGGG AGCAGCTGTC AATATAGATG AAGCTTTGCT 31980 CGCTCGCCTG CCACTCACCT CCTGCTGTGT GGTCCACTTC CTAACAGGTC ACAGACTGGT 32040 ACTGGTCCAT GGCCAGGGAG TTGGGACCCT GTCTTAGGGA GTAGGGGTGG AGTTCCCTTC 32100 ACTTCTAGAA GGCCCTGGAT TAGTATCCCA GAGCTGTCAT TACAGAGTAT CACAAACCAG 32160 GTGGCTAAAA ACAGACATGA ATTCTCTCTT ATTTTTGATG GCTTGGAAGT CCAAAGTCAA 32220 GGTGCTGCCA GGGCCATGCT CCCTCTGAAA TGTGTAGGGG AGAATCCTTC CTTCCTCTTT 32280 CTAGCTTCTG GTGGTTTGCT GGCAATCACT GGCATCGCTT GGCTTGCAGC ACTTCAACAT 32340 CTGCCTTTAC TGTCTCATAG TGTTCTCCCC TCATGTCTCC AGGTCTCTCT GTCTCTCTTC 32400 TTTGTATAAG GAAACTAGTC ATATTGGATT AAGGGCCAAC CCTACTCTAG TATGACCTCA 32460 TCTTAAGGTC ACATGCAATG ACTATTCCAG ATAAGGTCAC ATTCTGAAGA ACTGGGAGTT 32520 AGGACTTCAT ATCTTTTGAA GGAACACAGT TCAACCAATA ACAGCCCCTG TACTGTTTTA 32580 CAAATAGGTA TTCCTCTCCT TCCCAAAGTT CTTCATAGCA GAGACAACTT GTACCAAAAG 32640 GCAAAATACC TTATTATGTA ACCTTAACCT AGGATCATAG ATCCCTACTT GTCTGGTGCT 32700 TTTATAAGCC ACAGAACCAC CCGGGAAATC ATTATTAAGA CAAGGAAAGG CCAAGTGCAG 32760 TGGTTCATGC CTGTAATCCC AGCACTTTGG GAAATTGAGG CGAGTGGATC ACCTGAAGTC 32820 AAGAGTTTGA GACCAAACTG ACCAGCATGA CAGAACCCCA TCTTTACTAA AAATACAAAA 32880 ATTAGTTGGG CATGGTGGCA TGTGCCTGTA ATCCCAGCTA CTCAAAAGAC TGAGGCAGGA 32940 AAATCACTTG AACCGAGGAT GCCAAGATAG CAGTGAGCCA ATATCGTGCC ACTGCACTCC 33000 AGTCTGGATG ATAGAGCAAG ATCCTGTCTC AAAAAATTAA TAAATAAATA AAAAGACAAG 33060 GAAAGCCTTT TCCAAGGAGA CCCTTCTGCT TTGCTAGTTC AGAGAACTTC TCTTTGGAGA 33120 AAACAAACAC CCAGTCCATT AGCAGCAACG TCAGGGATTG AATTCTTAGG GCAGCAGGCT 33180 GGGCACAGTG GCTCATGCCT GTAATCCCAG TACTTTGGGA GGCTGAGATG GGTGGATCAC 33240 TTGACATCAG GTGTTCGAGA CCAGCCTGGC CAACATGGTG AAAACTCATC TCTACAAAAA 33300 <BR> <BR> <BR> <BR> <BR> <BR> <BR> ATATGAAAAA DATA AAAAG CTGGGTGTGT TGGCTTATGC CTGTAGTCTC AGCTACCTGG 33360 GAGGCTGAAG CAGGAGAATC ACTTGAACCC GGGAGTTGGA GGTTGCAGTG AGCTGAGATT 33420 GCCCTACTGT ACTCCAACCT GGGTGACAGA GAGAGACTCC ATCTCAAAAA AATAAAGAAT 33480 TCTTCGGGCA GCAGTCTTTC CTCCACCTCA TAGACCATGG AGGTGAGCCA GCTCTGACAA 33540 ACCATGAGAA CAATGGCAGA GACATACCTG TAACGTAACT GACTGGGGCA AAGACAAAGG 33600 TGAGGAAAAT GACAAGTTTG AGGAACTATG AGACCAGGCA GTGGGGAACA CCACTAGCAG 33660 AAATGATGGA AGTTCTCAAG AATAACAACA GAGAAATAGA CCATGGCCAG AGTCTAGAAC 33720 CCTCCAGGGA AAGGAGATGG GCTCCAGAGG CAGAAGAGGA CGTTGAAGGG AATGGGGAGT 33780 GGGTGAAATA TATAGACGAT GGGGACCACC CAAGAGCAGT CGCTATTGCA AAACTGAGGA 33840 GAAGGAGAGT CTGGAGGGGG TGGTGGGAAG CTGGGTCTCC TAAGGAGGTT TTGACAAAAG 33900 CAGTCATGGA GCGGGCTTAG AAATCACAGT TGGGGACAGG GTAAAGTTCC TCGGGATATA 33960 GAGGATGAGA TTAGAAGAGG TTCCAACTAG GGTAGTGTGG AGAAAAGCAC TATTGACCCA 34020 AAAAGGAAGG AGAATGTGGG TGGAAGTGGC AGAGAAAGAG GGGTTTGAGC AGAGAGTGGT 34080 GATTTTTCTA ATGCAGAGTT GTGGGAGGTG GAGTGCAGGG AGCCAGGCTG GGTGGCTGTG 34140 CTGATGTGAT TAAGCACTTA CTGACTGCCA GGCAATGGGC TAAGTACCTG AGATGCTTTG 34200 TCTGTTATCC CTCCCGAAAC CCCTCTGAGC AGGTGCAGTT ATTATTCTCA CTTCACAGAT 34260 AAGGAAATTG AGGCACAGAG AATTGAGTAA CTTACCCAAG GTGACATAGC TCATATATGG 34320 TAAAGCAGGC TTTGAACTCA GTCTAGCTCC CGAACCTAAG CTTGTAACTA CTATGCTTTT 34380 CCCAAAAAAA GGGGGCTGGC ACAAAAAGAG CTGAGGGGGG CTGGGCATGG TGGCTCATGC 34440 CTGTAATCCC AGCACTTCGG GAGACTGAGG CAGGTGGTTC ACCAGAGGTC AGGAGTTCGA 34500 GACCAGCCTG GTCAACATGG TGAAGCCCTG TCTCTACTAA AAATACAAAA ATTAGCTGGG 34560 TGTGGTGGTG TGCACCTGTA GTCCCAGCTA CTTTGGGAGG CTGAGGCAGG AGAATCGCTT 34620 GAACCCCAGA GGCGGATGTT GTAGTGAGCC AAGATCATGC CACTGGACTC CAGCCTGGGT 34680 GACAGAGTGA GACTCCATCC AAAAAAAAGA AGAGCTGAGG TGATGGCCAC CATCAGCATC 34740 AGCCTGGAAG TTATAGCAGG ATGCTAAGTT TCTCTAAAGC TGTCTTTCTT AGGACTTGAA 34800 AAAGATAACT TGGGTTTGTA TCCCATCTCT GCCATTAGTA GTTTACTGGC TTTGGATAAA 34860 TTACTTAGCC TTACTGAACC AACTTTGGAT TTTTATAGAG ATACTGTAAT GAAAGGAATA 34920 AGGTATCAGT CTTAGCAGAG CATCCAGAGT GTTCCTATTA AAACCTAAAT CATATCCTGT 34980 CATTGCTCTG CCCCAAACCA TTCAATGGCT TCCCAACTCA AAGTTAAAAA CTCATCTTTC 35040 CAGTGGCCTG CAAGAGCCTA TGCTATCCGG TGTCTGACCT CATCTGTTGT TCCTTTCTCC 35100 CTCCCTTTCT TGGCTCCAGA CGCACTCTGG TCTCCTTGCT GTTCCTTGAA TACACCAGGC 35160 ACACTCTTTT CACCTGAAAC ACTTTACCCC AGATATCTTA GCTTACTCTC TGCCTCCCTC 35220 AATTCATTGA TGAAATGTCT CAGTGAAGTC TTCTCTCTCT CCTCTGTAAA AGTATACTCT 35280 CTGTTCCCCT TCTTTACTGT TCTAGCTACT ATTGCTGTGT AACAAATCAC TCCCCAAATT 35340 TAATGAGTGA AAACATCAGC CATCATCTTA TTTCTCACGG TTTCTGAGGG TCAGGAATTC 35400 TGGAAGGGCT CAGCTGGGAG GTTCTGGCTC TATAATCTCT TATGCAGTGA GAGTCAGATG 35460 CTGGCTAAAA CTGAAACAAA GCAGGGTTCT AGTAGCTGAG GGCTGGCTGG GTCTCTCAGA 35520 TATAGTTCAG ATCTCCTCCA GGGGGTCTCT CCACGTGGGC TAGTCTGAAC TTCCTCACAG 35580 CATGGTGGCC TCAGGGCAGT GGACTCTGCA TAGTGGCTGA AGGCTTCGCA GCTGAGTATT 35640 CCAGCAAGCA AAGTGGGAGC TGTATTGCCT CATATGACCC AACCTTGGAA TCCACACAGC 35700 ATCACTTCCG TGTATTCTAC GGGTTGAAAA GTCACAAAAA CCAACCAGTT TCAAGGAGAA 35760 GGAACAGAGA TCACATTTCT CAATTGGAGA AGGGTCAAAG TCACATTGTA ATCAGAGCCT 35820 ATGGGATACG AAGTATTGCG GTCAGGTATG AAAAATTTGA TTTGCTGCAT CTGCTTTACT 35880 TTCTCCACAG CGTTCATGAT CTGCTTCTCA CATGATATTG ACTTACGTCA TTTCTGCATT 35940 TCCTGTCTTC CACACTAAAA TGTCAGCCTG TTTTGTTCAC TGCTGTATCC CCAGAGCCTA 36000 GCACGGAGCC CAGCATGTAG TGGTATCCAA TAAATACTTG TTGCATGAAT GAATTCTGTC 36060 TTTTAATCCT AGCTATAGGT TTCTAAGTTA AATATTACTA TAATCATCTT ACAGACGAGG 36120 GAAATGAGGC TCAAGAAGAT TTGGTAACTT ATGCGGGATC ACTCAGCCAC ATAATGGAAG 36180 AGACAGCATT GAAGTACACA TGCTTGCTCT GTCTGCTCTT CCAAGCTGCT CATCACACAG 36240 CTGCACCTCT GAGGACTTCC CTCCCCAGTC CACCTCCACC CTTACCCAGA GACACACATG 36300 GCCACAATCC ACTAGCAGAC CAAAATTCAA TTTTTCCCCA GTTGGTTGCA CTCAAGCTGA 36360 GAGCAAAGCA ATTGCACTTT AAATCCCCTT ACAGCAGATA TTTCAGAGCA TGTTCGGAAG 36420 AACCCATCAC ACTTGGCTTT TAGATCTTAT TTCTGGTTTG TTACAAAAAC ACAATTAAAT 36480 GAAAGGTTAG GTAGCTTTTG AATGGCCAGC TCAAAGTTTT GGCTTATTTT TGCCTTGCTG 36540 TCTTTATAGG CATTTTACCA ATATTTATCA CTATTTCCCT TAGGGAACCC TTAGATCTGT 36600 GATATTTGAA ATAATAAAGC CTCTCCATTG GCCCTTTAAA AGGTTTGTGG TAAAACCACA 36660 CCATTAACAT TCACAGTTCC TTATTTATGA GGCCTGATTG CACTTATTTC CATATTTCTC 36720 ACTGTTTCTC CGATGAGGAT TTCACATAAT AGTGTTTGAA GGCTAAAGAC TTCAAAGCAG 36780 ATTCTTTACT ATTTTTATCT TGAAAAATAT TCAATATTTG TGTAATTAAA GTGAAGTCTT 36840 CCTAGAGAAA ATGACAACTC AAATAATCTT AAATGTACCT CCAAGAAAAA AGCTGTCAAA 36900 GTGACATTTA GTAGTAGAGT CACATTCTCT AAGGCCTTTG CTTCTCCTTC TGAGTTCTTA 36960 TCATCTTTGA AGGTTATGTC ATGGCTGACT TCAAATCACT TTTAAAATTA TTATGGCCTT 37020 CTTTAAATGT GAGTTCTGAA GGTGAGGGGC TTTATCTTTC TTTTGCTCCA GATTTTTTCT 37080 ACCGCGTCAT TACCAAGCAT CTTAAAACAA AACCTAAAAA CAAAAATCTT CCTTGACCTG 37140 GTTTTTCCCA CTAGCTAACA TCCTATTTTT ATCTTTCCCT TTGCACTAAA GGTTTTTAAA 37200 CGGATCTTTA TACCCTCTGT CTCCATTTTC TCATCTGCTA ACTTATATGG CAAAGATTAC 37260 CACTGCCTTT CAACATAATT GGCCAATCTA CAGAAAGTTT TCAAGTTCTC TTTTTAATTG 37320 ACCACCTCCT GCCTACCTCC CCACCTTTGA CATCTTGCTT CTCACTTGGC ACCTTACCCA 37380 GTGTTCAAGA TTCCCTCCTT TAGGATGTCT TCAGAGCAGC TACACAGTTG GTACTATAAT 37440 TTATACATCC TTGTACACAG GGCTTGCTGG GATATTGATG GAGAGAAGGA GGAAACTGGA 37500 AGTAGTTCAG GCCAGAGCTA GGGAAATTGA CCCATCTCCA GGTCTCAGGT CTGCAAGGGG 37560 AGCTCACAGC TTAACACATG GAGTCTAGAA ACTTGTGCTG GACCTTGACC AACACCAGCC 37620 CATGGAGTCC AATACAGTGC TCAATAGGGA TTTCCAGGAA ATTGCTATAT TTATTCAAAG 37680 AGAACTTACC AAGTGTCAGC TACGTGTTGG GCATTGTGTT AGGCACAGGG ACCACAAAGA 37740 TAAGACATTG TAGCTTTCCT TAAGTTGCTC ACTGAGTAAA TAGAGAGACA GAAAGGTAAA 37800 CAGGTAAGTG CAAAAATACA TACAATTCTG CAATAGTGTT CATAGTGGCT ATGGAGAGAA 37860 CGCTCACTAA CTTTGTTTAA ACAGTTGTTC TTTCAAGGAT TTGACATGGA TTTGATTGGA 37920 AAAGCATGAT ACCATTTTTT GCAATTAAAC ACAGGAATAC ATAAATAAAA TGCATCAGTA 37980 TTTTTTACAA ATAGCTACTA AGAGCTACTA GAAAACCTGG GAATTCTTAA AACCTTACCA 38040 TGCTACTTGC TCTAAAATAT TTTATTTTAT GTTATTTTGT ACATTTCTTT ACCTACACAA 38100 ACACCACTGT TTTCTTCATT TCTTAGTCTA TTTAAACCTC ACACCCTTTC AGCATCTCTT 38160 AATTATTTAC TACCATCTGT TAGTTCTCCT GTCCTGAATG AAACAAAAAT GGCAGAATGT 38220 AAAACGAGGG CGAACAGATT TTTGACAGGA AGTATTCAGA GGTAGAAGGA AATAGTCAAG 38280 ACACATATGA TAAACGAAAA CAATAATAAC TTTATACATA ACAACTTATA GACACATTTA 38340 AAAAGTTTAA GATCTCAAGA GCTATGTCTG AATAGATAGA AGTAAAAACT CTATTAAGTA 38400 ATTAGGAAAA TAACAAGAAC AGTGAATTTC TTAATGAATG GCATGTAATC AAAACTGTAC 38460 TTATCGTCTA ATTCATAATC TTGAATGTTT TTATTTTATT TATTTATTTT TTTATTTTTT 38520 GAGACAGAGT CTTGCTCTGT CACCCAGGCT AGAGTACAGT GGCGTGATCT CAGCTCACTG 38580 CAACCTCCAC CTCCCAGGTT CAAGCGATTC TGCTGCCTCA GCCTCCTGAG TAGCTGGGAT 38640 TACAGAGGCC TGCCACTGCA CCCGGCTAAT TTCTGTATTT TTAGTAGAGA TGGGGTTTCA 38700 CCATCTTGGC CAGGCTGGTC TTGAACTCCT GACCTCATGA TCCACCAGCC TTGGCCTCCC 38760 AAAGTGCTGG GATTACAGGC GTGAGCCACC ACGCCTGGTC GAATGTTTTT ATTATTTGAA 38820 GAGACAACAT GGGCCTTAAA TCTGTCTTCT ATTTGACAGA CTTTGATGGA GTCAAATCCC 38880 AATGCTGCCA CTTACTGAAC GGCCTTAAAT GACTTAGTCT CTCTCAGCTG TCTTTCTGCA 38940 TATGTAAGGT GGAATAATGA TGGCTTCAAG GAGGAATAAA CCTATGAAAA GTGTTGAGGA 39000 TAGTGTCTGA TATGAAATAA GGATTCAACA AGTAGTAGCT GCTATTGAAG ATTTAAGAGT 39060 TATTTATTAC AACTATTTAA TAAAATTTTA AAAACTAATA CACTTAAATT ATTAAAGAGC 39120 TTTGAAATGG GCCAGGCGCA GTAGCTCCTG CCTGTAATCC CAACACTTTG GGAGGCCAAG 39180 GTGGGCGGAT CACCTGAGGT CAGGAGTTTA AGACCAGCCT GGCCAACATG GTGAAACCCT 39240 GTCTCTACTA AAAACGCAAA AATTAGCCAG GTGTGGTGGC ATGCACCTGT AGTCCCAACT 39300 ACTCAGGAGG TTGAGGGAGG AGAATTGCTT GAACCTAGGA GCTGGAGGTT GCAGTGACCC 39360 GAGATGTCAC TGCACTCCAG CCTGGCAACA GAGCAAGACT CCATAAAGAC AACAAAAGCT 39420 TTGAAATTGT GTAAATGAGT TGTACCTATC TTCATTTAAG AAATTCATCT TTGTTCATCT 39480 ATTTTTACTT GACATGAGAG CTTCCAGCAA TTTTTAATTA AGCCCTCACA GATTTTATGT 39540 CACTGGCTAT GTGATAAACA AATTATTTGC TAAAATAATA TTCTTGCTTC TTTTTTAAGG 39600 AATTGTCTCC CTAGAAACGG TTTGTACCAA ACAATACACT GACTTTACAC AAAATCAGAT 39660 CTGATTGGCA ACAGTTGCAG ATGTTTTCAA AGGATTTTCA TTTGAGAAGG GGCCCATTTG 39720 GGTTATTTAG ATTCTAAGAA CTGAAACTGC TTTGTTCTGT TTTTCTGGCT TCTGGGAGAG 39780 GAGGAGACAT GAATTCAGTT AGCACCTTGG TATTTTCTTT ATCCTTCATT TCAATACAGA 39840 AGATGCTTCA TATGCACAGT GGTGTCAGGT CACATCAAAA GAAAGAGAAA CAGTTTCTTG 39900 GTTTTTAATT TTCAACCGGA AAGGAAAGGC ACCCATTTTG TTCCGCTCTA ATTAGCCAGT 39960 GCATGACTTA GAGAGCAGGC AGATGCTTTG AAGGCGTGGT AACACAGGTC TTCATTAATC 40020 TCCACGCAGG ACTTGCACTT CTACTATGCC TAGGCTGAAG AAAATGGCTC AGGAAGATGA 40080 ACAATCTCAC AGAGCCCTAA CTAACTGAAG CCAGGTGTTA TAAAGCACAA GTCAAGAGGG 40140 TGAGAAACTA ACGTTCTTGA AATCTCCCAC TTCTTTCTAC GTCAGAAGAG CCAAGCTGAT 40200 TATTTTAGTT GGAATTTAGA AATTTTTAAA AATTATTCTA AAGTCATGAA CAAGCCTAAT 40260 TATAAAGATA GTTGCTGTGA AGGTGCTGAA ATAACTCGAT TTTACCAACC CCCTCTTCTG 40320 GAGGAAGCCA GAATGGAATC CTGTAGAATG TTCACTCTAC CAACGAACTC TTGTTTTTCT 40380 AATGAGGAAA CAGAGGCCCA CAGTAGTAAA CTATCTTAAC CAAGACAAAA TGACTAGTGC 40440 TCTGGTCCTT TTATTAAGCA CTAAAATTTT GATCCAATAA TAAATCTGTC CAGTAGAAGG 40500 AGTTTCCCTA ATGTACTGGT TCTAACTTGT TCCCTTCAAG GGGCCAGTGT CCCGTACACA 40560 TAGCTAAATG GGACTTCTCT TCAACTACCA TTACCCAGAG GGCAGAACCT AAAATGCTGT 40620 GAATGACATT CTGCTGTTCA CATCTCAGCA GCAGTGTTGC ATTTGAGCTT CTGCAGGGCC 40680 ACCCAGGACC TATATCTGCT CAGATGTTTA ACTCATCTAA TTCAGTGAAC ACTTCATTCT 40740 AGTTAACTGA ACATCTACTT TGTACAAGGC ACTACAGCGG TTCAGAGATG AATAAAATCA 40800 TGAGATTCCA CTGTCTCCTA TAAACCATCA CTTTGGGAAA TTTTAGAAAT GTGGGTAAGC 40860 TCCAGGGCTT CCTGCAGCGT AGAAGTCACA AACTCAAATG CCTGCAGAGG CCCAGCTGAC 40920 AACATAAGTA AATGATTCTG GCTGGGCGGA AAACAATTAC GGGTGGGTGG GTTTCCAGCT 40980 GGGGAGTGCA CGCCTGTGTT AAAGGACA 41008 (2) INFORMATION FOR SEQ ID NO:4b: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 39238 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:4b: GCTGCTACTC ATTTCCAGCC AACTGTGTTC CCATGTAGAA CTGCGGCCCA GTGTAGCCAG 60 TACCGAAGAT TTCTCAGAAA AAGCCGGAGA TCTCAATGTT AGTGTAAAAT CTCTCAAATT 120 TCCAAGAGGA TTATATGGGG CAAAGGTTCT CAGATCAGTT TGCAGTCTCT TACTTAGCCC 180 ATGTGCAGAG CAGTCGTAGA GGGTAGCATG CAGTGTCCTA CATAATAATT CTTTTTTATT 240 TTATTTTATG CCTTCCTCCT TCCTGTCTCT CTTTAACCTT TCTTCTTCCC TCAGGCTGGC 300 TTCTTCCCTC AGCCTCGTCC GACCCCAGCC TGGGTTCAAT GAACATTCGG TAAAGGAACA 360 CGGAATGTCA AGCGCATTAG AGACAACCTT GAGACACATT CCTCTTGCGG TAAGCACTTC 420 ACTGTAGATT TTTAATTTTA AACAAGACAA TGTTTACGAC TTGCTTCTTT CAGGGAAGAG 480 CGATATCAAT TTTAGTGAAC ACTTCAAGGC TGAGATACGC TAGGAGAGTC GTGTGGTGTT 540 GCACAGCAAA GAATTCCACT TTGAAGCGAG TGGGAAAAAA AGCATCAAAT GCCACATGTA 600 ACTCACCGCC TGAAGGGTTA CATTGGTATG AAACCTGGGT TTAAAAAGGG ACCGAATAGA 660 CTAGCCATTA AAAGACCTGC GTACAACCTC TCTCTCTCTC TTTGAGAGAT AATGTATCTG 720 GACAATAAAC ATGAACAGAG TGGAGTCTAT CCTGTTTAAA ACATTGCCTA CTGTACAGGC 780 ACCAGGAGCT GAAGGGTCAG AATATTAGCA GTGGGAGCTT GATTAGAAGT TGATGAGAGA 840 TGGGTAGTAG GAGGAAAGAG TGAGATAGAG GAAGAGGACA TGGGGGTTAC CCGTAAGTGG 900 AGAGTAGAAA AGTAGAATCA GCTGGCCATC AAAGGGCGTG GGACTGAGGA ACAGTATGGC 960 ATGTATTAAA TATACTAAGC GCTGACATTG GAGGAGAACT AGGAAGGTAA ATGAAATCAA 1020 TAGGGGATGA TGGAGAATAG TTAGGTGTGC AGGGATTAGG GTTATGATAG AAATACATGT 1080 GAATACATGC AGTATTGTCC TGGAAAATGG TTAACAGTTG GTTCTCCTGG GGGGTGAGGG 1140 GAAGCCCTGA TTTGTAATAT TTGCCTATTT CTGTGGTGCA AATACTCCCA CCATGACCAG 1200 TTTCAAGCTA TGAATGTGAA TCACAAAAGC AGGTTGGGAG GAGATGCGCA CATTTGTTCC 1260 CCGGCAAGGT GGAAGGTAAG GAAGGTGAAA TCAACAAGGT CAAAGAAAAC TCAAGATTTC 1320 GAGGTGCCTC AGGTCTGAGG GGCAATGAAG TCTAGGAATG GCTGTGCTGA GGTAGCTGAA 1380 ATAGAAGTGA CTGCAGAGGT CATGAAGCTG AAGAGGTGAA AACAGAAATT AGAAAGGCAA 1440 ACCCCCACCG CCCAACCCCC ACCCCTGCAG CCAGTTTCTG AGGGTGACAA TAGAGGAAAG 1500 GGTGGAGATG GAGTTCAGGT CCAGAAGCCA TAGAAGCGAG TGTGACATTG TGCTCAAGGT 1560 CAGCACATGT CAGTGTGGGG TGTCACATGC TGTTGTGAAC CATCATTTAT CACCAATTAT 1620 GGAAGACCTC CTATGGGCAT CTTGCCATAT GCATTATAAA GATGTGTAAG AAGACATTTC 1680 CCTCCACTTG GTGAGGAGAA TTAGGGCTGT ACACAGATAC TGTAGAGTGC CATGTGCCTG 1740 GTACAGATAA GGTGTGTTAG AGGTTAAAAG ATGAGGCTCT TAATATTAAT GATAGATCCC 1800 ACTTACCTGA GTCTGACTTA CAATGTGCCT AGCATTAAGT GTTTTACCTG CATTCCCTTT 1860 GACCTTCAGA ACAACCCATT TTACAGATAG GGAAATTGGG TCAGAAAGTT TCAGTAACTT 1920 ATCCAAGGTC ACACAATTGG CAAGTGCCAG AGCTGAGCCA GGAACTGAGG TCCTTCTAAC 1980 ACCAAACAGC TTGTCTCCCC AATCACTGTG CTATTTTCCC TCCCCCAGAA GATAATACTC 2040 TGATGGAAAT GAAGGATAGT GTAATAGGAG ATTCGGTGTT CCTTTTTTTA AAAAAAATTC 2100 AGCTTGCATA TTCCTAAAGA GTCAATTCAT GTTTAAAAAA AATTTCCCTT GTGCTTGCAT 2160 GTGACATGTA TTTTTAGGAT CTGCTGTTAG CAAGTGTATT TTTGTGTGAT TGAGTGGGAG 2220 AGTGGGAAAA GTTTTGCAGA GCTGTTGAAG CCAGAATGCA GGGGGGCTGC GCAGCAGAGA 2280 CTGTAAAATC TCTGCCATCT CAGGTCTTGG AACAAGCACA AAGAGATGTG TTCTCGATTT 2340 ATTATTCTAT GTACATCCCC AGATGAATGA CTAGTTAAAG GTATTGTTAA AGCATTTTAA 2400 ATGACCCACT TCCAGCAGCG AACAAAATCA CTTGCTGTGC CAAGCCAACT GGCATTTCTG 2460 AGATGATAAA ACCACAAAGT GAGGAAAACG TTAAAACTGC TAAAGCAAAA ATGATACACA 2520 ATAATGGAGA AGGAGAAAAA TTGAGCTTTA TTGTCTGCCT AGGCAGATGG CTGACCACTA 2580 GGTGGGCTCG GCGTCACGTC CAGGGTAATT GGTTGCTGGG GTGTTTCTGG CGAGGAAGAT 2640 TCACGCTTCA GCTCGGTCCA CAAGATCCTG GCTCATTCTT TCCTAGATTC CATTTTCTGC 2700 CTCCTCTCCA TGACTGGGTC TGATGGTTGA TCCAAACGGG CAATTGAAAT CAGAAGGTTA 2760 CCTTTACCTT AAAATGCTTT TCTGGAAATA AAAGGACATG AAAAGTAACT AAGGACCGGA 2820 TTTCCTAGCC GTCTTTCTCT CCTGCATGCG CAATTTATCC CCAGATATAA AATTGCCTGC 2880 TTTGATAATT ATACCCTCTA AATGAGGGGC AAGTGGCTAA TTATGCCCAC ATGTGGCCGA 2940 TTGCACTCCC CATTAGCCAA TTATGTGCTC AATTATTTGT GCACATGAAT AATTGCACTC 3000 ATGGAAAATA GCGGCCCTCC TTTCAAATCC TCGTGCTTGG AGTGGCTGAT GGAGTAATTG 3060 TCACACTGGA AATGCACTTG GTGGGGAGGG AAAGAGTATC AGATACCAGG AAACGCATAA 3120 GTGACCAGAG CTCGCAGATG TTCACTGCCA CAAATGGCCT TAGGAGCCAG AGAGAGCGGG 3180 AAGGACCACA GGATGGAACG GGCCAGCCTG TGAGTTAGGA AGCCTGCTTC TGAAGTTGCC 3240 TGGGCAGCTC ATGTGCGGTG ACCTTGGGCA AGTCATTAAC TTTCCTTCAG GTCTAACTGG 3300 TTCTGCATAC ACAATGAGGA TGGTAATAAC GCCCAATTCC CATCACTATC GTGGGATGGA 3360 TCAGACTATT TAAAAGGATT TACAATCTGC TTGGGTAAAA GCTTTACATA AATATGAGGC 3420 ATTATCATGT CGCTTGGTAC ATCTCCAATT ATGAAGGAAG GGTAATGACC CTCCACAGCA 3480 ATGCAGGACT CCTGGTTTGG AGGGAGGGAA AGTTTGAGAA GGACAGGAAG CTTGTTGCCC 3540 CAGCACTGAT GTTTCTACTG AGGTACCAGA AAATGTCATG TGGTCATACA GAATTCATTT 3600 ATTCATTCAA CAAACATCTG TCAATTGTTA CACTGTCCTG AGAATTTGGA AAAATGATGA 3660 AAGACTCAGT CCTGCCTTAG GAGGTCACTG GCACATTGGC CCGGGCCCCT GTTTTGGGCC 3720 TTTTACTCTG ACCTGTGCTG ATTTGCAAAT AGTGGGAAAT TTTATCTCAA GTCTAGGAAA 3780 TCTGGCATGC ATTTTCACGG TTTGATTGCC AGGTACATTC GATGGCAATG AGTCTTATAA 3840 TGTTTGGTTA CCTTCATTTA CCTAAAAACT GTGGTTGTTG CTGTGGTTGT TGTTTTTGTT 3900 GTTTTTGAGA CGGAGTCTTG CTCTGTCATC CAGGCTGGAG TGCAGTGGCA TGATCTCCGG 3960 TCACTGCAAA CTCCACCTCC CAGGTTCAAG CGATTCTCAT GCCTCAGCCC CCTCAGTAGC 4020 TGGATTACAG GCGCGCACCA CCATGCCCGG CTAATTTTTG TATTTTTAGT GGAGACAGAG 4080 TTTCACCATG TTTGGCCAGG CTGGTCTCGA ACTCCTGATC TCTGGTGATC CGCCTGCCTC 4140 GGCCTCCCAA AGTGCTGTGA TTACAGGCGT GAGCCACTGT GCCCAGCCAG AACTGTGGTT 4200 TTAATGACAA TGCTAAAAAG TGGTATATGT CACAGTGTCG GGTGGGGCTA AGAGGCACAT 4260 TGCTGCAGTG ATCCATCATT CATTTCCCAC CATTCTCGCC TGGATTAGCG CAGCAGCTCC 4320 CAGAGAGGCA CCTCACTTTG ACCTTCTTCC TCAAAGACAT TCTCTGTGAC CTGCCTGGCC 4380 CTTATTACCT CTCTAGCTTT GCCACTTCCC TATGTCTCCA TCTCCCCTCT CACACGTAGT 4440 AAGAAAGAGA CTCTACCTCC ATGGAAGTTA AGGAGAGGTT TCACAGAGGC AGGATTGCTT 4500 ATTAGTCTTC AAAGATGAGG TATTTGCTAA ATGAATGAGA CAAAGGGATT GGGGCCACAT 4560 TACAGGAAAT TGAGGTATGT AATAGCCTGG TGCAGGTTAA GAGTGTGGAC TCTGAAACCA 4620 GACTCAGCCT GGAATTGAAT CCTGGCTGTG TGATGTTGGG CCAGTGACTT AACCTCTCTG 4680 TGCTTTTATT CACTCTTCTA TAAAATGGGG ATTATAATAA ACCTACCTTA TAAGGTTATT 4740 ATAAGAGTCA GTAAATATAA AAATAGAAGT TTTTGGATGA TGACTAGCAC AGAGTAAACA 4800 CTTGTTTGCC ATTATTTTTA TTACTTGACT AAAAATATAC CAAAAAGACC ATCCAAGAAA 4860 AGCCTTTAAG CTGCTAGTGC AGAAAGATTC CCCTTGTGTT TGTGTGCTGG GGGGTCAGTG 4920 GTGCCTGTGG CCCACTGGAG AGGAGACAGC TATGGCTGGA GTGATTCTCA AACTTCAGAA 4980 TGTCTAAAAT CATCACATGG ACAACTTATT AAGGAAAGCA AATGCCTGGG CTCCATCCTC 5040 AGAGAGTCTC ATTCACTGGG TCAGGATAGA GCCCAGGAAT CTTTACCTTA AAGAACCATC 5100 CCACCTCCCA CCTCATATGA TCCTTATGCA GGTGATCTGG GGGCCCACAC TTTGAGAAAT 5160 AGACTCAGGT CAAAGTGGGC TCTAACTGCA TCTCATTTCT TACCTGGCAT ATCTAATAGT 5220 AGAGAAGAAG ACAATGCTAA GATTTTTGTT GGAGATCTTT TGCTGGGATT GCTGCTTCAT 5280 TCATTCACTC ATTTATTTAT TTATTTATTT ATTTTGAAAC AGAGTCTCAC TTTGTCACCC 5340 AGGCTGGAGG GCAGTGGCAC AATCTGAGCT CACTGCAGCC TCAGGCTCCT GGGTTCAATC 5400 GATTCTCTTG CCTCAGCCTC CCGAGTAGCT GGGATTACAG TCATGCACCA CCACGCCCAA 5460 CTAATTCTTG TATTTTTAGT AGTGACAGCG TTTCACCATG TTAGCTAGAC TGGTCTCGAA 5520 CTCCTGACAT CAGGTAATCT GCCTGCCTCG GCCTCTCAAA ATTAGTAGCT GCAATTACAC 5580 GTGTGAGCTG CCGTGCCTGG CCTGCTGTTT CTTTTAGTTG GGCCTCTTCT GTAATAGAGT 5640 GTGAGAATTC TGACTTGCTG CAACAGTCTG CTTTGAAGCA GGGCTGTGTT TACACTGGTC 5700 AGATGTGGAA TTGTGGGGCA CACTTAGCAG CTTCCTTCTC TAATTTTTCT GTATTTTCAG 5760 GAGAACAATT TTAAAAAATT TAATAAAAAT GCCTTAAAAA TTAACATTAT TATAAGATGA 5820 ATCCCATTTT TCTAATCTTG TAAATTAAAA ACAATCATAA GCATATGAGC ACCTGCACTT 5880 AGGGAATCAA GGTGGCAAAG CTAAACACTT CCAGCTCTAG GTGATTCGCG GCAATACAAA 5940 TGGAGCTGGA CTTTGGCCAC AGTGCAAAAA TATTGATCTG TTGTTAGATG CTCTGAAGTT 6000 TCCACAAAGA ATTGGTTCTG CCTGCTGTGC TTCAGTGCTT AAGGGAAGTG GTTCCTCAAA 6060 ATGTTAGTTT TTAAGCCCAG CTTTCTTAAA TAGGAAGATT CTAATAGTAG CAAAAATATA 6120 AACTGCTTCT AGGTTTAAAA AGGACCAGCA CACAATGGTT ATCACACACC TTTCTCCTCA 6180 GGTGATGAGT GGATGAGTGG CCTGGTGTAT TTCATAACAT CTCCCAGGGT CCAAATGCTA 6240 AAGCAATTGC TGAAAAGATA CCATGTGTAC CGGAACCTTG CAGAGGTATT TTGTTGGCAT 6300 AAAAAGAAAT ATTGATCATC TATAGTAAAA ATGGTTCTAC TTTAATACTA CTGAGAAAAG 6360 ATTTTCTTTT CCCAGATCTA CATCCTGAAT CTTCATGAAG ACAAGATCCC CTAAACTTCC 6420 ACTAACACCA TAATGTGTGC TGTCCTTTGT AATGTAGTCC ACAGATCTCA TAAACTGTCA 6480 GAAATAGCAG AGATTGTAAG GTCATCCACT TCCCCTGTAA GGCCTGCGTC CCTCACTTAC 6540 ATCCCTAATA ACGTCCTCTA ACCTCTGCTG GAGGGCAGAT TTAGCTGCCA GCTGGGAAGA 6600 GCTCTGCCCT AGTCAACATT TTTATCTGTG GCTTTCAGAT GAGAACACTG GATGCTTATC 6660 TGAAAAAAGC TCCTCAGGCT GGAGGGAGGG ATTGGCTCTA ACAAGATGCA ATGTGATAAG 6720 AATAAAAGCG AAGCCAAACT CTAGGCCCAA AGGCTCTAGC AACACACTTT TGAGAACCTT 6780 GGAGACGAGT TTTGGCTGAT GCGAGCTTCT CCGCCTGCTA AAGTAGCCCA TTCCATTTGG 6840 ACGGCTCTAG AGGCTGGCAT GTTCTTCTCC ACGTTGTGTT AATGTACTCC AGTTTCTTCC 6900 TGCCATGAAC TGGCATGCCC TGGCTCCTCC TACCTTCCCC ACTTTAAGTC TTCCCTCCCT 6960 CCTTCTGACC TTCCCATTCC AGCCACACTG GCCTTTTGTC TGGTCCTAAC AAACCATGCC 7020 TTTCCTGCCT CCAAGCCCTA CACCTGCTAT CCATCCCTCT GTCTGAGAGA CACTCCCACC 7080 CCTTCACAAA GCCTGTTTCT CATCCTTCCA GTTCAGATGT CTTCTCAGCT TGCCTCAACT 7140 GACCTCTTTC AGCTATTCTC ACTCTTTGTA CTCTGTTCAT TTCCTTCCTG GCAGTCACCA 7200 TAATTTATCT TTATTTGAAT CAATTTCTTA GTTGTATTAT TTAGTTATTT GCACACTCTG 7260 TCTCTCTGTG CCTTTCTTAT TCACTGCAGG CTTTCTTATG TAAGTAATTT ATTTACTTAA 7320 ATTTTTAAAA ATAATTTCAA CTTTTGGCCG GGCACAGTGG CTCACGCCTG TAATCCCAGC 7380 ACTTTGGGAG GCCGAGGTGG GTAGATCAGC TGAGGTCAGG AGTTCGAGAC CAGCCTGGCC 7440 AACATGGTGA AATCCCATCT CTATTTAAAA TACAAAAACT AGCCGGGCGT GGTGGTATGC 7500 ACCTGTAATC CCAGCTACTC GGGAGGTTGA GGGAGGAGAA TCACTTGAAC CGGGGAGGTG 7560 GAGGTTGCAG TGAGCTGAGA TCACGCCATT GCACTCCAGC CTGGGGCACG AGAGTGAGAC 7620 TTCATCTCAA AAAAACAAAA AACAAAAAAC CCCTGCTTTT CAGAGGGGCT GAACTAATTT 7680 ACATTCTCAC CAATAGTGTA TAAGCATTCC CCTTTCTCTA CAGCCTCACT AGCATTTACT 7740 TTTTTAR9AA ACTTTTTAAT AATAGCCATT CTGACTGGTA TGAGATGGTA TCTCCTTGTG 7800 GTTTTCACTT GCAATTCTCT GATGATTAGT GATATTGAGC ATTGTTTTAT GTTTGTTGGC 7860 TGTTCGTATG TCTTCTTTTG AGAAGTGTCT TTTCATATAT TCTGCCCATT TTTTGAATGG 7920 AGTTGTTTTG TGCTTGTTGA ATTAAGTTCC TTATAGATTC TAGATATTAG ACTTTTGTTG 7980 GATGCATAGT TTGTGAATAT TTTCTCCCAT CCTATAGTTC TGTTTACTCT GTTGATAGTT 8040 CCTGTTTTGT TATGTTTTGT TTTTTTGCTG TACAGAAGCT GTTTAATCTA ATTGGTCCCA 8100 CTTGTCAATT TTTGTTTTTG TTGCAATGGC TTTTGAATTT TAATAATAAA TTCTTTCCTA 8160 AGGCTGATGC CCAGAACAGC ATTTTCTAGG TTTTCTTCTA GGATTCTTAT AGTTCAAAGT 8220 CTTATATTTA AGCTTTTAAT CCACCTCAAG TTAATTTTTA TATATAGTGA AATGCAGGGG 8280 TCCTGTTTCA TTCTTTTGCA TGTGGCCAGC CAGCAATCCC AGAACCATTT ATTGAATAAG 8340 GAATCTTTTC CTCATTGCTT ATTTTGTCAA CTTTGTCAAA GATCGGATGA CTGTAGGAGT 8400 GTGGCTTTTT CTGGGTTATC TACTCTGTTA CATTGGTCTA TGTGTCTGTT TTTGTATCAG 8460 TATCATGCTG TTTTTGTTAC TATGGTCTCA TAACATAGTT TAAAGTTGGA TAATGTTATG 8520 CCTCTGCTTT GCTGTTTTTG CTTAAGATTG CTTTGGCTAT TGAGGCTCTT TTTTCACTTC 8580 ATATGAATTT TAGAATAGTT TTTTCTAATT CTTTGAAAAA TGACCTTGGC AGTTTGATAG 8640 GAATAGCATT GAATCTATAG ATTGCTTTGG GCAGTATGCT ATTTTAATGA TATTGATTCT 8700 TCCTATCCAT GAGCATGGAA TATTTTTCCA TTTGTTTGTG TCATCTACTA TTTCCTTTAG 8760 CAATGTTTTT TAGTTTTCCT TGTAGAGATC CTCCTAGGTA TTTCATTTTT TATGTGACTA 8820 TTTTAAATGG GATTGCATTC TTCATGTGGC TCTCAGCTTG AATGTTATTG GTGTATAGAA 8880 ATGCTACAGA GTTTTGTACA CTGATTCTGT ATCCTGAAAC CTTACTGAAG TCATTTATCA 8940 GTTCTAGGAG CCTTTGGCAA AGTCTGTAGT GTTTTCTAGG TATAGAATCA TATCATTAGC 9000 AAAGAAAGAT AGTTTGACTT CTTCTTTTCC TATTTGAATG CCTTTTATTT CTTTCCCTTG 9060 TCTGATTGCT CTTCCAGTAC TACGTTGAAT AGGAGTGCTG AGAGTGAGCA TCCTTGTCTT 9120 GTTCCACCTC TCAAGGGAAA TGGTTCCAGC TTTTGCCCAT TCAATATGAT GTTGGCCATG 9180 GGTTTGTCAC AGATGGCTCT TATTATTTTG AGGTGTATTC CTTTGATGCC TAGTTTGTCA 9240 AAGGCCTTTA TCATGAAGGG ATGTTGGATT TTATTGAAAG CTTTTTCTGG GTCTTATTTG 9300 GTGAATTGCA TTTATTGAAT TGTGCATGTT GAGCCAAACT TCCATCCCAG GGATTAAACC 9360 TACTTAATCA TGGTGTTAAC TTTTTGATGT GCTGCTGGAT TTGGTTTGCT AATTTTTTTT 9420 TTTTTTTTAA AATGGATTCT CCCTCTGTCC CCCAGGCTGG ATTGCAGTGG TGTGATCTTG 9480 GCTCACTGCA AGCTCCACCT CCCGATTTCA TGCCATTCTC CTGCCTCAGC CTCCCGATTA 9540 GCTGGGACTA CAGGCACCCG CTACCATACC CAGCTAATTT TTGTATTTTT TAGTAAAAAC 9600 AGGATTTCAC CATGTTAGCC AGGATGGTCT TGATCTCCTG ACCTCGTGAT CTGCCTGCCT 9660 CAGCCTCCCA AAGTGGCTAG TATTTTTTTA ATTACTATTT TTTCTCACCC TTGCTGCCAT 9720 CTTATGATTT TCTAGTATTT TGTTGAAGAT TTTTGCATCT ATTTTCATCA GGGATATTGG 9780 CCTGTAATTT TCTTTTTTCA TTTCATCTTT ACCACATTTT TGTATCAGGT TCATACTGGC 9840 TTCATAGAAT GAGTTCAGGA ATGGTCCCTC CTCCTCGAAT TTTCTCTGTA GAATTAGTAC 9900 CAGCTCTTTG TGTGTCTGGG AGAAGTTGTA TGCCAATAAT TTAAATGCAG TTAATATTTA 9960 CTGGACAATT TCCTCCAGAT AATTGTATAT GATTTTTGGT CCACCCTGAG TTGATACATG 10020 TATTTTAATT GTATCATGGT ATGAAAAGAG CAAGAGTATT TGGTCACCTA GTCTTGCCTA 10080 TAGATGTGCC TAATGATTCA AAGTAGATAT TTTGGGAGCC TAACAGGTGC CGTGACTAGG 10140 CAGTTTTGTT TTTTTTTTTT TTTGAGACAG AGTCTCGTTA TGCTGCCCAG GCTGGAGTGC 10200 AGTGGCATGA TCTCGGCTCA CTGCAACATC CGCCTCCTGG GTTCAAGCAA TTATACTGCC 10260 TCAGCCTCCC CAGTAGCTGG GACTACAGGC TCACGCCACC ACGCCTGGCT AATTTTTGTA 10320 TTTTTAGTAG AGATGGGGTT TCACCATATT GGCCAGGCTG GTGTTGAACT CCTGGCCTCA 10380 TGATCCACCC GCCTCGGCCT CCCAATGTGC TGGGCTTACA GGCGTGAGCC ACCGCACCCG 10440 GAGATTAGGC AATTTTATAT TCCCAAATAT CCAACTCTTC TGACCCGCTT TCTCAGCCTG 10500 GGTGTATCAG GCACAAGGCC TGTTCAGATT ATGTGGTCTC TGAAGATATG GCTCTCCAGG 10560 GTTGACAATG TGGATAAGGA TTCACCTGGT TTAGGATTTA CACATTCGCC TTGAATGTCT 10620 GTTGCATCAA GTAGACAGTC CATCCCAACT TGGCCATTTG GTCAGAGCTG TAAGGAGACA 10680 AGGAGGTGGG CAGCCGCTGC TGTGAACTGC TTGGACAAAG ACTGCCAAAT AGCTATCAGA 10740 CAGTGTTAAC AACAGCTGAT TTAGGTTTGA AGGGGGCAGT CTCTTGGGCC ACTTACTATG 10800 CTGCATCATC CTCTTTGGAA AATGCTCTTC AGGTAACTGC CTAACAGACT GAGAAAATAA 10860 AATGCTCACA GAGAAAAAAG ACCCGGAAAG TCTGACTTCT CAGAGCTCAG TGTTTAGGTG 10920 CAGAACTGGA TTGTGAAAGG ATTTTTAAAT TTTTTATATT CATTGCAGGG AACATTCATT 10980 TATTCCATCC TTCTCCACTC CCACCTGTCT GTCGTTGTCT TTGTCTCTGT CTCCCCACCT 11040 CTCTCTCTAG ACACACACAC ACACACACAC ACACACACAC ACACACACAC ACACACACAC 11100 ACACACACAC ACACACACAC ACACACACCC CTATTCATTG CCAACAGTAA TAGAGTTGCT 11160 TCTTTACTTC TTGGAGAGAA AAGCCTCAAT CTGAGGAAGC TGTGCTGACT AGCCTTGCTC 11220 TTAATCATGG AGACAATGCT TTATGCCTTT ATCTTTGCAC AGCTGAAAGC CATGGCAGAA 11280 GCAGTCCTCT AAACGAAATA AAATAGAAAG GTTCCTGCTA AGCCCTGGCA AATGCAGCCT 11340 TCTATCCCTC CCCCAACACT CACAGCTTCT GAGCAAGATG TAGCTGCCTT CCAGGAGGCT 11400 GGGTGATGGG CAATAATGAG CAGAGCCACG TGAAGGAAAG ATGGGTGAAG AAATGTGTGT 11460 GGAGGTCATG CTGGCTGCAC TGACCATGAA ACAAAGGATC TACCCCTCTA GTAACTGCCC 11520 TACTCCTTTG GTAACTGTTC TGAAATTATA ACTTGCCAGA AGTTCAGAAG GACCTAGTGC 11580 AGGTATTAGA GGAAATTCGT AAGATTGAGC CATTTATTCC TGCACAGATA CATAATAATG 11640 GACACGGGCC ATGGTGGCCA GCATTCTTGC TCTTGACAAT GGTGAAGGGA AGGGTTGTAG 11700 GTCATGGCTA TGCTCTCAGA ATTATAATGG AAAGAAACAG CTCCTGAGTG TTTACTATGA 11760 GCCAAGGGCT GTGCTAAACA CTTTACCATA TGATGACATC TTTTTCTCAC AGGTATCAAA 11820 AAACAATAGG ACATACCGGA TAGCTACAAT CTTTGGGCCC CTGCAAACAC AATAATGTGT 11880 ATTCTCTTCT TCAAATCCTA CATATTGCTA CAAACTGTAT CCCTGAGGCA TATTCATTGT 11940 AAAATAAAAA CATATAAAGT ACTACTTTTG TTTTTTGAGA TGGAGTCTCG CTCTGTCACC 12000 CAGACTGGAG TGCAATAGCA TGATCGTGGC TCACTGCAAC CCCCTGCTCC TGGGCTCAAG 12060 TGATTCTCCT GACTCAGCCT CTCAAGTAGC TGGGATTACA GGCGCACGCC CCCATGCCTG 12120 GCTAATTTTT GTACTTTTAA TAGAGACCAG GTTTCACCAT GTTGGCCAGG CTGGTCTCAA 12180 ACTCCTGACC TCAAGTGATC CACCTGCCTC GGCCTTCCAA AGTGCTGGCA TTACAGATGT 12240 GAGCCACTGC ACCCGGCCCA TATAAAGTAC TACTAATGTA ACAGGGTGCT AGTCCAGACA 12300 GTGACCACAC GTGGTGTTCA TTGAAGGCTG GACTAACAAC TCCAGCCTCT CCGCCATCAC 12360 AGAGTGATGA CTGCCTTCCC TGAAGCAAAG CTTCTGGTTC AAGGAAAGGC CAGTAAGTGA 12420 CTGCTCTTTG TTGTATACAT GTTAGATGAT CAGGCCTCAA GAAAAGTATA AAGAGATCTT 12480 TGTGCTCTCT GGGACTCAAA AAGCTGCACT CTTTGGGGGA AGGATAGCCA GGTAAAAGTG 12540 GCCCAGGTAA AGAGGGCCTG GTACACCTGG TTCTGCAAGA TGGTAGACAC AAAAATGAGA 12600 GCCACATTTG GAGCTTATGT GCCCCTAACT CTGTACATAA CCTGCAAGAT CTAATTACTA 12660 ACAACTGGAA TCTTGGAAAC ACCTGTAGTA CATCCTTGGC TAAGGTTAGC CCCAACAGAG 12720 AGGGCTCTCC TCTTACAGAG AACCATTACA TTTGTGCCTT CATCCTAGAG TAGAAAAGGC 12780 ATGATCAGAC TACTAAAAAG ACATCAGGAA AGGGCCTGTG ACATCTGAGG GAAGTGGTTG 12840 CCCTCTCTGG GATGTTGGTT CGGGAAGAGG GGCATGGAGG AGTGCCTGCT TTAGATGGTC 12900 ATTCAGGAAC CCAGGCTGAT AGTGAGAGGT GAAGCCAGCT GGGCTTCTGG GCTAGGGGGG 12960 ACTTGGAGAA CTTTTGTGTC TAGCTAAAGG ATTGTAAATG CACCAATCAG CACTCTGTAA 13020 AATGGACCAA TCAGCACTCT GTAAAATGGA CCAATCAGCA GGATGTGGGC AGGGCCAAAT 13080 AAGGGAATAA AAGCTGGCCA CCAGAGCCAG CAGTGGCAAA CTGCTCAGGT CCCCTTCCAC 13140 GCTGTGGAAG CTTTGTTCTT TTGCTCTTCA CAATAAATCT TGCTGCTGCT CACTCTTTGG 13200 GTCTGCACTA TCTTTATGAG CTGTAACACT CACCGTGAGG GTCTGTGGCT TCATTCCTGA 13260 AGTCAGTGAG ACCACAAACC CACTGGGAGG AACAAACAAC TCTGGACACG CCAACTTTAA 13320 GAGCTGTAAC ATTCACTGCG AAGGTCTGCG GCTTCACCTC TGAAGTCAGC GAGACTATGA 13380 ACCCACTGGA AGGAAGAAAC TCCAGACACA TCTGAACATC TGAAGGAAGA AACTCCAGAC 13440 ACACCATCTT TAAGAGCTGT AACACTCACT GCAAGGGTCT GCGGCTTCAT TCTTGAAGTC 13500 AGCAAGACCA AGAACCCACT GGAAGGAAAC AATTCCGGAC ACATTTTGGT GACCCAGATG 13560 GGACTATCAC CAAGTGGTGA GTACCATCAA CCCCTTTCAC TTGTTATTCT GTCCTATTTT 13620 TCCTTAGAAT TCGGGGGCTA AATATTGGGC ACCTGTCAGC CAGTTAAAAG CGACTAGCAT 13680 GGCTGCCAGA CTTAAGAGAC TAAAGACACG GGTGTCAGAC TTTCTGGGAA AGGGCTCTCT 13740 AATAACCCCC AACTCTTTGG AGTTGGGAGC GTTGGTTTGC CTGGAACCAG CTTCCACATT 13800 TCCTGTACTT CTGGGCTGAG ACGAGGGTCA ACAGAGAGGA AAGCCATTCA GCTCTGGGGT 13860 CCCGACAGCA AGTTGGTTGA CCCTGTGGCC ATGAACAGAA CTCTCGAAGT CATGTTGCCC 13920 AAGCGAGACT CACCCATCTA TCCTATCTAT CCTGACTCTT GCTTCCTGGG TCCTAATGCC 13980 TGGAAGACAA AACTTCCTCT TGTCTCTGTT CTCCAAGGCT AGTCCCACTT CTAAAAACCA 14040 CTCCCTGTCT CTGGTGCTTT TCTAGTTTCT CCTATAAGAA TGATTTCTAG TATAAACTCC 14100 AGGACTCTAT TCTCTTCTTT AGGCACCCGG GCTCACCAAT CAGAAAGCCA TAATTTTTGC 14160 CCAAAGCCCC ATCTTAGGGG GGACTATCTG GAATTTTAGG ATCCCTCCTC AGACAAGCAG 14220 GCCTAACAAA AGCTATTCCT GAAGCTAGGA TATGGGGAGC CTCAGAAATG ATATCCTTCC 14280 TATTCAAGTG AGGACAAAAG GCATCACTCT TCCAATTCTG GAAATCCCTT CCCTCCCTCA 14340 GGGTATGGCC CTCCACTTCA CTTTTGGGGC ATAACGTCTT TATAGGACAC GGGTAAAGTC 14400 CCAATGCTAA CAGGAGAATG TTTAGGACTC TAACAGGTTT TCAAGAATGT GTCGGTAAGG 14460 GCCACTAAAT CCGATTTTTC TCAGTCCTCT TTGTGGTCTA GGAGGACAGG TAAGGGTGCA 14520 GGTTTTCAAA AATGTGTTGG TAAGGGCCAC TAAATCTGAC ATTCCTTGGT CCTCCTTGTG 14580 GTCTAGGAGG AAAACTAGTG TTTCTGCTGC TGCATCAGTG AGCGCAACTA TTCCAATCAA 14640 CAGGGTCCAG GGACCATTGT GGGTTCTTGG GCAAGAGGTG TTTCTGCTGC TGCATTGGTG 14700 GGCTCAACTA TTCCAATCAG CAGGGTCCAG TGACCTTTGC GGGTTCTTGG GTCGGGGGGT 14760 GGGGGGAACA AACAGACCAA AACTGGGGGC AGTTTTGTCT TTCAGATGGG AAACACTCAG 14820 GCACCAACAG GCTCACCCTT GAAATGTATC CTAAGCCATT GGGACTAATT TGACCCGCAA 14880 ACCCTGAAAA AGAGTGGCTC ATTTTATTCT GCACTATGGC CTGGTCCCAA TATTCTCTCT 14940 CTGATGGGGA AAAATGGCCA CCTGAAGGAA GTATAAATTA CAATACTATC CTGCAGCTTG 15000 ACCTTTTCTG TAAGAAGGAA AGCAAATGGA GTGAAATACC TTATGTCCAA ACTTTCTTTT 15060 CATTAAAGGA AAATCCACAA CTATGCAAAA CTTACAATTC ACATCCCACA AGAGGACCTC 15120 TCAGCTTACC CCCATATCAT AGCTTCCCTA TAGCTCCCCT TCCTATTAAT GATAAGCCTC 15180 CTTAATCTCC CCCACCCAGA AGGAAACAAG CAAAGAAATC TCCAAAGGAC CACAAAAACC 15240 CCTGGGCTAT CGGTTATGTC CCCTTCAAGC TGTAGCGGGG GAGGGGAATT TGGCCCAACC 15300 CAGGTACATG TCCCCTTCTC CCTCTCTGAT TTAAAGCAGA TCAAGGCAGA CCAGGGGAAG 15360 CTTTCAGATG ATCCTGATAG GTATACAGAT GTCCTACAGG GTCTAGGGCA AACCTTCAAT 15420 CTCACTTGGA GAGATGTCAT GCTATTGTTA GATCAAACCC TGGCCTTTAA TTTAAAGAAT 15480 GTGGCTTTAG CCACAGCCCG AGAGTTTGGA GATACCTGGT ATCTTAGTCA AGTAAATGAT 15540 AGAATGACAG CTGGGGAAAG GGACAAAGTC TCTCCCGGTC AGCAAGCCAT CCCTAGTGTG 15600 GATCCCCACT GGGACCTAGA CTCAGATCAT TGGGACTGGA GTCGCAAACA TCTGTTGACC 15660 TGTGTTCTAG AAAGACTAAG GAGAATTAGG AAAGAGCCTA TGAATTATTC AATGATGTCC 15720 ACCATAACTC AGGAAAAGGA AGAAAGTCTT GCCTTCCCTT GAGTGGCTAC AGGGAGGCCT 15780 TAAGGAAAAT ATAACTCCCC TGTCACCCAA CTCACTTCAA GGGTTAATTG ATTCTAAAAG 15840 ATATGTTTAT TACTCAATCA GCTGCAGATA TCAGGAGAAA GCTCCAAAAG CAAGCCCTTG 15900 GCCCTGAACA AAATCTGGAG GCATTATTAA ACCTGGCAAC CTTGGTGTTC TATAATAGGG 15960 GCCAAGAGGA GCAGGCCAAA ATGGAAAAGC GAGATAAGAG AAAGGCCACA GCCTTAGTCA 16020 TGGCCCTCAG ACAAACAAAC CTTGGTGGTT CAGAGAGGAC AGAAAATGGA GCAGGCCAAT 16080 CACCCAGTAG GGCTTGTTGT CAGTGTGGTT TGCAAGGACA GTTTAAAAAA GATTGTCCTA 16140 TGAGAAACAA GCTGCCCCCT CACCCATGTC CACTATGCTG AAGCAATCAC TGGAAGCCAC 16200 ACTGCCCCAA AGGACAAAGA TTATCTGGGC CAGAAGCCCC CAAGCAGATG ATCCAACCAC 16260 AGGACTGAGG GTGCTCAGGG TTAGCGCCAG CTCATGTCAT CACCCTCACT GAGCCCTGGG 16320 TACATTTAAC CATTGAGGGC CAGGAAATTG ACTTCCTACT GGACACTGGT GCGGCTTTCT 16380 CAGTGTTAAC CTCCTGTCCT GGACAGCTGT CCTCAAGGTC TGTTACCATC CGAGGAATCC 16440 TGGGACAGCC TATATCCAGG TATTTCTCCC ACCTCCTCAG TTGTAACTGG GAGACTTTGC 16500 TACAGATAGT AAGTATGCTT ACCTAATCCT ACATGCCCAT GCTGCGATAT GGAAAGAAAG 16560 GGAATTCCTA ACTTCTGGGT GAACCCCCAT TAAATATCAC AAGGAAACTA TGGAGTTATT 16620 GCACACAGTG CAAAAACCCA AGGAGGTGGC GGTCTTACAT TGCCGAAGCC ATCAAAAGGG 16680 GAAGGAGAGG GGAGAACTGC AGCATAAGTG GCTGGCAGAG GCAGGGAAAG ACAAGCAGAA 16740 AGGAAAGAGA GAAAGAGCAG AAAGTGAGAG AGAAAGAGAG ATAGGAAGTG ATAGCAAAGA 16800 GGGAGTCCGA AAGAAAAGAG AGAGGAGAGA GAGAGGGGGA AAGACAGAGA GAGACAGAGG 16860 AAGAGACAGA GAGACAGAAA GAGAGAAGCA AAGAGAGGAA GAGACAAAGA AGGAGTCAAA 16920 GAGAGGGAAA GAGAAGTAGT AAAGAAAAAA CAGTGTACCC TATTCCTTTA AAAGCCAGGT 16980 TAAATTTAAA ACCTATAATT GATAATTGAA GGCCTTTTCT GTAACCCTAT AATACTCCAA 17040 TACCACCTTG TTGTCAGTGT AAACAAGGGT ATAGCCCAAA AGCACTGAGG CCACTGACAA 17100 CCCGTAGCCT TCTTATCAAA AATCCTTAAC ACAGCAGGTT TCCTAACAGG GAATCTAAAT 17160 CTTAAGGTCG GACCAGACAT AGGAGGAACT GCCTTCAGGA CAGGATGATA GATGGTTCCT 17220 CCCAGGTGAT TAAGGAAAAA GACACAATGG GTATTCAGTA AGTGATAAGG AAACTCTTAT 17280 AGAAGCAGAG TTAGGAAAAT TGCCTAATAA GTGGTCTGCT CAAACGTTGA AGCTGTTTGC 17340 TGTTTGCACT CAGCTAAACC TTAAAGTACT TACAGAATCA GGAAGGAGCC ATCTATACCA 17400 ATTCTAAGTT AATATGGACT GAACGAGGTT TTATTAATAG CAAAGAAAAT TAAAATCTCA 17460 AACTTACAAG GTTTTCAACT AAAGTAAAGT TTGCTAAAAG TTAACAGCGT AACATGTATT 17520 ATCCTACTAC CTCACACTCT CTCAAAGGAT TTCTCAGACA GTTTGCAAAA AAGAACGAAA 17580 TCTGTCCTTA CTCTACAATC CCAAATAGAC TCTTTGGCAG CAGTGACTCT CCAAAACCGC 17640 TGAGGCCTAG ACTCTCTTAC TGCTGAGAAA GGAAGATTCT GCACTTCTTA GGGGTAGAGT 17700 GTTGTTTTTA TACTAACCAG TCAGGGATAA TATGAGATAC CACCCAGTGT TTACAGGAAA 17760 AGGCTTCTGA AATCAGACAA TGCCTTTCAA ACTCTTATAC CAACCTCTGG AGTTGGGCGA 17820 CATGGCTTCT CCCCTTTCTA GGTCCTGTGA CAGCCATCTT GCTAATAGTC GCATTTGGGC 17880 CCTGTATTTT TAACCTCTTG GTCAAATTTG TTTCCTCTAG GATCGAGGCC ATCAAGCTAC 17940 AGATGATCTT ACAAATGTAA CCCCAAATGA GCTCAACTAA CAACTTCTGC TGAGGACCCC 18000 TGGACCGACC CGCTGGCCCT TTCAATGGCC TAAAGAGCTC CCCTCTGGAG GACACTACCA 18060 CTGCAGGGCC CCTTCTTCAC CCCTATCCAG CAGGAAGTAG CTACAGCGGT CATCGCCAAA 18120 TCCCAACAGC AGCTGGGGTG TCCTGTTTGG AGGGGGGATT GAGAGGTGAA GCCAGCTGGG 18180 CTTCTGGGTC AGGTGGGGAC TTGGAGAACT TTTGTGTCTA GCTAAAGGAT TGTAAATGCA 18240 CCAATCAGCA CTCTGTGTCT AGCTAAAGGA TTGTAAATGC ACCAATCAGC ACTCTGTAAA 18300 ATGGACCAAT CAGCAGGATG TGGGCGGGGT CAAATAAGGG AGTAAAAACT GGCCACCCGA 18360 GCCAGCAGTG GCAACCCACT CGGGTCCCCT TCCACACTGT GGAAGCTTTG TTCTTTTGCT 18420 CTTCACAATA AATCTTGCTG CTGCTCATTC TTTGTGTCCA CACTACCTTT ATGAGCTGTA 18480 ACACTCACTG CGAGGGTCTG TGGCTTCATT CCTGAAGTCA ACAGACCACG AACCCACTGG 18540 AAGGAACAAA GAACTCCCGA TGTGCTGCCT TTAAGAGCTG TAACACTCAC TGCGAAGCTC 18600 TGCAGCTTCA CTCCTGAAGT CAGTGAGACC ACAAACCCAC CAGAAGGAAG AAACTCTGGA 18660 CACACCTGAA TATCTGAAGG AACAAACTCC AGACACACCA TCTTTCAGAG CTGTAACACT 18720 CACCGCAAGG GTCTGTGGCT TCATTCTTGA AGTCAGCAAG ACCAAGAACC CACCGGAAGG 18780 AACAAATTCC AGACACAGTA GGAAATCTGT ATTTTTGATC TGTGGCTTCC AGGGTTACTC 18840 CAGTCATTGA AGTCTCCATT GCAGCCTTAA GGAAACAGAG AATGGTTTGG AGGAGCACAT 18900 GTGGGAATTG TTATGGACCA GGCTTGAGAT GCACATAGGG CATTTCTGAT CAAACCTAGC 18960 TGGAAGCAGG GCCAGGAAAT ATAATCTAAG GAAGACAGTT TTTGTAGACA GTAGTAGTCT 19020 TTGCATCTGA GACATGTAGA TTATCAAGCA ATTAATTAGA AAAAATATAG CCAGGTGCGA 19080 TGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCCAAGG GGTGTGGATC ACAAGGTCAG 19140 GCGTTCGAGA CCAGCCTGGC CAACATGGTG AAACCCCGTC TCTACTAAAA ATACAAAAAT 19200 TAGCCTGGTG TGGTGGCACG CATCTGTAAT CCCAGTACTC AGGAGGCTGA GGCAGGGGAA 19260 TCTCTTGAAC TTGGGAGGCA GAGGTTGCAG TGAGCCAAGA TCACACCACA GCACTCCATC 19320 CTGGGTGACA GAGCGAGACT CTGTCTCAAA AAAAAAAAAA AAAAAAGGAA AGGAAAATAT 19380 AATCAAGAAT ATTGACAGGT AACATTTATT CAACACTTAC TATGCACCAG GCAATACACT 19440 AAGTGTTTTA CATGGATTAA CTCATTTAAT CTTAACAATA GCCCTATGAA GTCAGTGCTG 19500 TTATTATCTC CACTTTATAG ATAAGGAAAC TGAAGTACAG AAAGGTCAAG TAGAGAAATG 19560 GCCATGCTTG CATTCTCAGT TTTTGAAGCA ACTGTTACAG GAATCTGGTG TGAGAAATGC 19620 TCTAACAAGA TGTGAGTCAG GGGTTGGGAG GTACTGAGTC TGAGTTGGGC AGTTGGGGAT 19680 GGAAGGATGG ATGAAGAACA GCTTGACAGA GAAGCTGACA CTTGGCAACT CTGTGGGACC 19740 TTGAAGGGTT AGAGGGACTT CACCAAAGAA ACTGGTGGTC AGGGAAACGG GAGGGTCACG 19800 GCAAGGAGGG AAAGGAAACT GTACCACAGC AGAGAGTCTG AAGCTACTAC AGTGTAGTTC 19860 AGCGTATAAA GAATAATTAT TTTAAGGTAA ACTTATAACC TCATGCAAAT ATAAAATGAA 19920 CACGTGTCAA AGATCTTATT TAATTTATTA ATTAATGAGG GAACCTGTAA GATGTTACAG 19980 CCAGTTCAAA GGATAATTCA AATAAATCCA TGCACATATG TAGGCAATAA GGAATGCTGA 20040 AATGAATTTA AAAGTAGATG TAAACTGATT TATCCACAGA GAAATAATCA GTTGCATTTC 20100 ACATAACAAA ATTCAGTTGC TTTTCTACAG AAGGAATTGT TTGCATCATT ACCAATTTTT 20160 CTACAACTAA CAGAATTATA AAATAACTCA AACACAATGA AAGGCAGATA TAACCCACAA 20220 TGGTATGATA GATACAATAT CCACATCCAG GATGTTTTTT TCTCATTTCA AAGTCTTTCA 20280 CAAGTTTTCC TGATAAGGGA GTGTCAATAA TACTGTATGG CAGGCAATAA GACTGGATGG 20340 ATGGTTGGGG CCAGGTTTTA AGGGGTAATA AATGCCATGT AAAGGTATGT GCATACTGTG 20400 CAACATGTCG GGGGAATCTC AAATTATTGG TAGAGTATGT AGGAAACACT TGTGGGAGCT 20460 TGTTAATAAA TTCAAATTCC CAGACCCAAC TCCTCAAGGG GTCTAATACA GTAGGTTTGG 20520 AGTAAAGCCT GAAAATCTGC AATTGTGCAA AAAAAAAACC CAGGTGATTC TGATACACTT 20580 TGAGAAGCAC TGGTGGAACT AATAGTCACT GAACGTTTTT GAGCAGGGGA GAAACCTGAG 20640 GACGTCTATG TTGCAGCAGT GGAAACTTGA TTAGAAGTAG GAGAAGATGC ATGGTCTTAA 20700 AAGAATGCAA AATGATGGCT AATATTTGAG TGCTTATGAT GGGCCAGGGG CTGTGCTAGG 20760 CGCGTGGCAC ACATTCAATA CGATGGAAGC CTGTACCAGT CAGTATTAGT GGGGTATCTT 20820 TAAGAGTGAC CAGAATTAAG GGGGGTTTTC ACCAAAGCCT GAGGACTGAG CCTCCTCATC 20880 CTAAATTCAG ACACAATGCT GTACCTATGC ATTTGCCTCC AGGCTGTTCC TGGGCCTCCA 20940 GGGACTGGCC CAGGCTCCTG ATAAATAGGG ACTCCCAACA ACATAAAGCC TGGATTTTGG 21000 AACTTCCTGA ATGTTACTCA GGCTTTCTAG TAACTGTGGA GATCTGAATA ATAACACAAT 21060 TCTAAGTTCC CCTACTCATA AAGCTGCTCA TCATTTAGAT GGGGTAAAGC ACCTGAAATA 21120 CAATGAGCAT CACTATTTTC ATTCATCCAT GAAATGAACA TTCCGGGGAG ATCAGTAAGT 21180 TGATGTATCA CCCTTGAACA GGGCAAAATG AATACTCACC AGGAATATGT GGTATTTTAA 21240 AAAGAAGGCA AAGGGAAGAA TAGTGGGGAT GGGGCAAAAA CTTTAAATAG ATTCCCCCAA 21300 TCATATATGG CAATTGAAGA TAATTAAATT ATCATTTTAA TTGAGTAAGT ACTCATAGAG 21360 CCCTCACTAT TTGAAAATGA ACTGCCTCCT AATTGTTATT GTGCAAATGT GATACATTAA 21420 ACTTAAGCTA TTTTAATAAA ACATCCATTT TCGGAAGCTG TAGTAGGTTC TCCCAGGTCA 21480 GATTTGATAA GCCATAAAGA ACAAATGCCA ACTCCTATTT TTCTATGGTG CTGGGAAATA 21540 AGAGAGAAAT GTGTAATTCA AAGCAATCAT TTAATTTTAT CCAATAGCTT GATTCTCCTC 21600 TCTCTTCTAG CCTTTTAGCT AAGCTGTTAC CAAGTAACCA CACTAGTTGG CTTGAGTCTT 21660 ACCACTGTTT CCCTGACCCC ACAGTGGAGA GACTGCATCT GTTAAAGAGC AGTTATGTAA 21720 CCATGGCTAT GCTGAGCTGG GATTCCCAAG GCTTAGGTTC TTTCTGTGAA TGACCTTCAC 21780 CAAGACACCT GAGGTCTGTG TGGAACCACA GGCTTGTCAT CTCTAAGGCA GAGTTGATAA 21840 TTCCATCTGT TTCTTGAGCC CACACTGAGA AAAAGATTAC ATGACTGCAG TTATTTGAAT 21900 GCCTCATGGA AAGACGTCTT ATAAATATTA TAATTAATGT TATCATTAAG TAATGCTTCA 21960 ATGCAGATCT TCCAAGTATA AATATCAGCT GAGTAAGAAG TCAATCTTCC CTGAAGCAAA 22020 ATTGAAATTT GTAAATGCGA TTTCTGGGAG CTTATTTTGT AATACATGAT TCCAGAGTGT 22080 CCATAACACA CACAATTGTC TTTTTTCCCC TACATGGGCT ATTTACAACA AAATTGGACT 22140 TATAATGTTT ATTTCCAGGG ATGACTAGAA CTTTAATAAC AAACCTTGGG CCAGGCATAG 22200 TGGCTCATGC CTATAATCAC AGCACTTCGG GAGGCTGAGG CTGGTAGATT ACTTGAGGCC 22260 AGGAGTTTGA GAACAGCCTG GCCAACATGG CAAAACCCTG TCTCTACTAA AAATATAAAA 22320 ATTAGCCGGG TGTGGTGGCG CATGCCAGTA ATCCCAGTTA CTAAGTAGGC TGAGGTACGA 22380 CAATCGCTGG AACCTGGGAG GCGGAGGTTG CAGTGAGCTG AGATTGCACT ACTGCACTCC 22440 AGCCTGGGTG ACAGAGAAAG ACTCTGTCTC AAAAAA AA AAAAAAAATA ATAATAATAA 22500 TAAACCCTGA TGAAAGGTTT CTAAAATGTT TTCATCTAAT GGTTTTCTTG ACAATTAAAT 22560 TTTCTATATA ATGTCAGTTC ATAAAAAAAC TGAGAACGAC CACATGTCAT ATCGACTGCT 22620 TAAAAGAAAA TACGTATATT TACAAACATA TACACGATAC TGTCTTTTGT CTGGTTAGTT 22680 TAGAGGTTAG ATAAACTGCA GTATGTTGTA GTGGACAGAT CATAGAACTA GGAGTCAGGA 22740 TGTCTGGATT CCTAGGAAGC AATGAATAGG TTGCACGGTG CAGACCAGCA TCATGAGTAT 22800 CCTCAGGGAG CTTGTTAGAA CTGCAGATCC TTTAACTCAT TGAATCAGAA TCCCTAGGTG 22860 TGGGGCCCTG AAATCTGTAT TTTAGCAGGC TCTCTGGGAT TGTGATGTGC CTTAGAGTTT 22920 GACAACCACT GGGTAGCTGA TCCTGACTTA GACTTATCAG GCATGTGATC TTGAACAAGT 22980 CACATAATCT CACTGAGTTC AGTTTTCTTA TGCTTAAAAT AGGCCCAATA ATATCTATTT 23040 CACATGGACT GCTTTGAGGA TTAGGCAAGA GATCTGTAAC AGACACTGTA GAACAGTGTC 23100 TCTGGTCTAC AGCTGACCTT CCATAAATGG TAGTTGCCTT GATCTCTGCT CTGCCACATA 23160 ATAGCTGGTT AACTATGAGC AAGTAATTTA GTTCTTCTCA GTTTAGTTTC TTCACCTGTA 23220 AAAGAAGGAA AATAACTGTT ATACTCAATT TCTGAAGTGG CTATAAAAAT CAGTTTAAAT 23280 TATGGGCATT GAAGCTCTTT GTACACTGTA TAAGGACTGT ACATCTAAGG GATTAATGAG 23340 ACCAGGCTTA TGATTTTAAG CATGGAGTAA ATAGTAACAC TGACTCTGTT CTATGAACCA 23400 CATGGAAACT CTAAAGAATA TGCACATTTG AAACACAGGT ATCATCTGGG GAAGGTGATC 23460 TGCTCACCCA AACCAGTTCA TGAACATCAA TCTCCAGTGG CGTGCTGGAG CTAGCTGTAC 23520 CAGCTCATGA GGGCCAATTG TTTCATTTTT AGGAATTTTG TTTGCTGGTT AAAAATAGTC 23580 ATTATTTAAA ATTAAATTAT GTAAACAATA ATATTAGATA AAATAAGTTA AAATAAAAAC 23640 AAAGGAACTA ATTATCCCCA AACTCTTCCC CACCTAATTA TTTTACTATC TGTGCCTTGG 23700 GATTATTTAC ATTGATTTTA TCCATATGGT GACAATACTA TTCATATATA AATGGTGTGC 23760 TTCTCTTCAT AACTCTACAT AGCCTGATGT CAGGCTAGTA GCTTGAAATT GGCCACAGTG 23820 GGAGTGTGAG CATTTGTACC ATGAGGCTTG GCCAAGGCTA CAAATCCAGA CTTTTGTTTT 23880 TCCCTCCTGG AGAGCTGTCT GTTAAAAATT TACCAACACA CCACTGGTCT TACCTTTGTT 23940 AATTTACCAC AGTCCAGGTT CTGACCTAGA CTTAGAAACC TGGATTTGTC AGCAAGCTGA 24000 GGATAGAGCC ATTATTTTTA AGAAGGACTC ACATTACCCA AGTGCAAAGC CTGATATATA 24060 CCTTCAGAAT ATCAATTTAT TAATTTACAG TGAAGAAAGC CACCCCAGGG CATTCCCCAG 24120 GGGAAGGCAA AAAGAGCTAG TTGCACATTT TGAATGTTTG ATGACATTAG GGTAAGGTGA 24180 CACAGAATAT CCATTTCCAC AACTGAGATA CCTGCTGCCT TAAGGAAGGG ACAGGCAAGT 24240 CCTTGGGCAG GACCTTAGAT TGTCACTGTC CATCTTGCTC TAGGACTCTC CTTTCCAGGC 24300 ATGACGATGG CCAACTCTGT CCTCCTACCC TACTGATGGG ATTATCTTTT CTTGACACAT 24360 GGCAATGCCT CCAATCAGAG GCTGGTAGCT ATTTTTAATC TTCAGGGCAG TATTTTTCAA 24420 AGGGAAGTTC ATGGACCATA TGCATCTGTA TCATTTAGAT GTATATTAAA AATGCTTAGT 24480 CTTCCCCAGT TATACTAGAT CAGAATCTCT GTTGGTGGGG CCCACGAATC GGTATTTTCA 24540 ACAAATCACT AGGTAATTTC TGTATATACT ATAGTGTGAA GACCACTGCT TGAAGGTTTC 24600 TTTGCATATC TCCACTAAAT ATAAAAAATA TTGACTTCTA GATTTAACTC CCAAAGCACT 24660 TGCATTTTTA AGTTTCTGGG GGCATTATAT TGTGGTACCC CTATACCACT CACACTCTAG 24720 TCAGGAGGTA TATTATGGAC TGAATGTTTG TGTCCCTCCA AAACTCATAT GTTGAAGTCT 24780 TAGCTTCCAA TGTGATAGTA TTAGGAGATG GTGCCTTCTG GAGGTAAAAT CAAGCCCTCA 24840 TGAATGGGAT TAGTGCCTTT AGAAAGAGAG CTCCGTCACT GTCTTTCCAT CAATTGAAGA 24900 TGCAGTGAGA AGCTGGTAGT CTTGCATCTG GAAGAGGGCC CTCACACAAC CTGATCATGC 24960 TGGCACCTGG TCTCAGACTT TCTGCCTCCA GAACTATGAG ATGATAAATT TCTGTTGTTC 25020 ATACCCCACC CAGGCTACAA TATTAGGTTG CTGCAAAGTA TTTGTGATTT TTGCCTTTAC 25080 TTTTCAGGGC AAAAACTGCA ATTACTTTTG TGCCAACCTA ATATTTTGTT ATAGCAGCCC 25140 GAACTAAGGC AAGGGAGACT ACATCAGACA GTGTAGCTAT GTAAGTACAA ATGTATCCCT 25200 GTTGAGGAAA ACTAAGTTCT AACCCTGACT TCAGGCCAGT AGCCACCTTT TCAATCTCTT 25260 TCATGAAGGG ACCATTATCA TTATCACTGG TGGCAAAAAT AGAGGCACGA GAATGGAATT 25320 TGCTTTTCTG TGAAATCTCA GTGTATACAG ATTGAAGAGC AAGGGTTTGC TTTCATCTCT 25380 AAGAAGCAAA AGTGAGTACG GACTGGCACA TTATCAGAGA AAGAATCATT CTAGCTCGGT 25440 GGGTCTTAAC CAGGAGTGAA TTTGACTCCA GGGAACAGTT GGCAATGTCT GGAGACGTTT 25500 TTATTTGTTA TAGCTGGGGG ATGAGTGGGT GGGTTGCTAC TGGCATCTAG TGGGTGGAGA 25560 CCAGAGATGC TGTTAAACAT CCCGCAAAGC ACAGGACAGT CCCCGACAAC AAAGAATTAT 25620 CTGGCCCCAA ATATCAATAG TGCCAAAGTT GAGAAACCTC ATTCTAGCTT CCTTTTCCCT 25680 TCTACGTTCT AATCAACTGT TGTTCTTTCA GCATTAGGAT TCATCCAGCA GTCTCTTTCC 25740 CCAGCAATTT GTTGAAATTT TTTTAAAAAT GGACTCATTT TAGTGTCACA AGAAAAAAAT 25800 ACATTCACAG GAAAGGATGG GTCATTTTGT TTAATGATGT TTTGCCTTTC ACATAGCAAA 25860 AGCTTAATAA AGTATTTTTA AATAAAATGG TGAATAGATC AAAACATTAA TTTCACATGT 25920 GTTTTAATAA ATAACAGGAA GATGGCTATA TTATATAAAT TGTTCTTGTA TATGTCTTGA 25980 GTGGATCATC AAACACAAAC GTATCTACAT GCCTTTTCTT GTGAATAGAT CTAATAATAA 26040 CGCTCTTCTA AAAACAAATT AAATGGATAT TATTTGCTGA GAATGTAATG CTTGTGTGAA 26100 TAGAAGCCAG CCCTGAATCC AAGCCCCCAG ATCTATTTAA AGAATTTGAA GAATGTCAGA 26160 AAAGCACGTG GCTTCAAGGT TAATGTGTAA GACTCACAGA AACTTGAAAA ATCACTATGA 26220 CTAAAAAGAA AGTATGAGCT CCCTGCATGC CTGTAAATTG GAATGACAGC CAAAACCAGT 26280 TAATTATAAA AACAGCTAAT TTAACAGGTT TTCAAATTTG TTTCTTTCTC CAAGTAGCAT 26340 ATAGTCAATA ATCCTTAAAG AGAAAGCAAA GAAGGGGAAG CACTGAACCA AATTTGCTTT 26400 TTTGTACCTG CTCAGCTCAA ATGCAGAGTT CTCTACCTGG AAATTGACTG CTTCCATAGT 26460 TTGATAGCCA CAGAGAGATG GGAACAGAAG GAGAGGTATA ATCCCAGACT TGATTCAGCT 26520 ATAGAGAATG ACAATAGTGT CAGAGGCCTT CCAACCAGAG CGACTCCATC TTGAATACGG 26580 GCTGGGTAAA ACAGGGCTGA GACCTACTGG GCTGCATTCC CAGGAGGCTA AGCATTCTAA 26640 GTCACAGGAT GAGACAGGAG GTCAGCACAA GACCTTGCTG ATAAAACAGG TTGTAATAAA 26700 GAAGCCAGCC AAAACCCACC AAAACCAAGA TGGCCATGAG AGTTATCTGT GGTTGGTCTC 26760 ACTGCTCATT GTATGCTAAT TATAATGTAT TAGCATGTTA AAAGACACTC CCACCAGTGC 26820 TATGACAGTT TACAGGTACA TTGGCAACTT CCGGAAGTTA CCCTCTATGG TCTAAAAAGG 26880 GGAGGAACCC TCACCTCCCA GAATTGCCCA CCCCTTTCCT GGAAAACTTG TGAATAATTC 26940 ACCCTTGTTC AGCATATAAT CAAGAAGTAA CTGTAAGTAT CCTTAGGCCA GAAGCTCAGG 27000 CCACTGCTCT GAATGTGGAA TAGCCATTCT TTTATCCTTT ACTTTCTTAA TAAACTTGCT 27060 TTCACTTTAC TGTATGGACT CCCTGTGAAT TCTTTCTTGC AAGAGATCCA AGAACTCTCT 27120 CTTGGGGTCT GGATCAGGAC CTCTTTCCAG TAACAATAGT AGTAAGGGGT CAGGGAGACT 27180 GGACAAAGGA GTTTAAGAAG CCTTAGATAA AGGGTCCTCA TCATTGTCAT AACATAAAAT 27240 CATGGACTCC TAGAATTTTA TAGCTGATAG GATTAGAAAT TTCAAAATTC AATTTCATTA 27300 ATTTTCATCT GCGAAAACAG ATGGCCAGAG AGGCCAAACA ATTTGTTAAG GAGCACTGAG 27360 GGCAGACCAC ACTGGAACGC AAACCTCTTA GCAGAGTATA CAAGGCCTTT GATCTCCTCA 27420 GTCAGAATGA ACTAGAGCTT TCCAGGGTAC CCTTTCTGAC TGTTTAGCAT GTTTGCCAGT 27480 CTGACTAATT TTGAAGTTGC TTAAATATCT GTCATTTCCA CTGTATCATA ATCTCCTCAT 27540 TCATCTTCAA TCTCCAATGC CTTGAACTCA GTAAATGTTA GTTGAACAAA AGTAAATTGA 27600 ACCCAGAATT TCTGATCATA ATCTGGAGCA CTTTAAAATT GTCAGCTTAC TGGGAAACGG 27660 GATAACATGT GATTTGTCTT TGATTTTTTT TTTCTCATAT GCTTTTTCCA CCTATAGATG 27720 CTACACGAAT GTTTTTAAAA TCTGATATAA AAATTAAAAT TAAAAAATTA AAAAAAGAAA 27780 ATTTGATACA ATGCTACATT TAGAGTGTTG TGATTAGATT CCTTAAGTGT ATCATGGTGA 27840 TCTCTACATC ACGTGGTGAT CAAATTGCTT TGGGTTTTAA CACATAACTG ACAAAGGCTT 27900 GGGGACATGT AAGATCCCAA ATACATTTTT ATTGATTTTT TTTTCTTGTT TGTCCTCTTT 27960 TAAATAACTT TTTTTTGTTA TAAGAATAAT TCATGTTCAG TGGAGAAACC ATAGAAAATA 28020 GTGACAAGTG AAGGAATAAA TTTAAAATGA CCCATAATTG TACCATACAT TCTGATTTTT 28080 TAAACGCTGA ACAAATTAGC CTTGGGTAAG TACCAGGAAT AGAGTGCAGC ATTGAAAGTT 28140 AAAGTTTGGG GAAGGATAGC TGACTTAAGA AATTATCTAG TTAGACATTT TTTGATGGGG 28200 TAATTTTGCA GATGACATTA GTGAGAGAAA GGACTTGCCA CTCTCACACA GCTAGTAGGG 28260 GTGTGGGAGG ATATTGGAAC CAAGTTTCAA GTCTTCAGTG AAGAATCAAG GGAGAAGTTC 28320 TAAAACCTAA CAATATCCCT CTGGATGGAC ATTTATTTTA TTACTACAAT AAGCCACACG 28380 GTGAGTCATA AGGAGCATTT CATTCTTCTA ATATGTCTCT ACTGTATTTA GAATCTGATA 28440 AAGCCCCTAT TAGAATTCAT CTCTTTAAGA ATAAAAGAAG CTGAGGAACT AAAGAGAGGG 28500 TTGGAATAAT CCACTAATTA TATCCGTTAA GCTTCAGTTA CGCTAATAAG GAATATCACA 28560 TGACTGTGGT GTGTGCTTGT TCTGAACAGT AAAGTACATG AGGAAAGATA AGATTCAGGG 28620 CTGAAATGTC CTTCAGCATA TGTAGGTAGT GGTGATGAAA GTCATTAAAA GAAAAATTGA 28680 TTGAGGTATT TTAGTAAACA AAAGAACTCA CCACTTACCC ATCAGGAAGT GTATTGTTAA 28740 TGCAGTGCTG TTCAGCCTTC TGGAAGAAAA GGTTTCTTCA TGCTTCTCTC TTTAGCCTAA 28800 TTCTTATCCT GTCACTTTTC AGGCAAAATT AAAA AAAA AAAGATTGAA AACGATGCTC 28860 CTATTTTATT TGCTTCAAAA GAAACAGGCT GTTGCATTGT GCTTGGAACA GTTTACTCTT 28920 GGCCTTGATG TAAGTGTGAA AGGAAGCCCA TGTAATTGAC TAGGCAGTAT CTGAAGAAGC 28980 AGGAAATACA GTGTTAAGAA AATGAACAGG CATGAAAACC ATGGCTATTT GATAAAAGTA 29040 AATAATTTCT GCAGTTCACA TGTTCTCAGC ATATTTTCTT TGATACTGAC TTGCTTAATA 29100 TGACAATAGC AGAACCATGG TAGCTTGTAG GCATTACTTT TCTTTTAATT TCTTTTACAT 29160 TTTGAATTTA CCAGCACTCA CATTTGTATT ACTTTTGGGT TATACTGAGG ATCTATAACT 29220 TATAGATCAA ATACCTGACA TATATATGCA TTCTCTGAAG TCTTAGGGCA GAACTAGAAC 29280 ATTCTTGTGA ACATCAGTAT AAGATATTAA AATGGAAGTT TTGCCTAAGA CTGAAGACAA 29340 TAAAAATATC ATAGTCTGAA ATGAATGCCA GCACACCATA CAGGATTTAA ATATCTATAC 29400 ATATATATGT GTGTGTATTA TATATATTTA ATATATATCT GTGTGGGATA GGAAGAGGTA 29460 GGGGGAAATC AGTTTTACAA TTATTAAGTA TTTCACCCTT GACAAGAGTA TATATATTGG 29520 AAATCAGTTG GAGAGTATTT TCAAAGATAA ATGTTAGTGT GCTATGAATG AATCCACCCC 29580 TACCACCACT GAGGCAGGGT AGGAGAGGCC TGTGCTCCTC AAGCATAGTT GGAAAAGGAC 29640 CTCAACAAGA CCACTTCAAG AGTCTAATGT GTGGAGACTG TTGCTTAGGG AGACCTTATG 29700 GTCTAGCTTC TGACTCACAG CTAAGTCAGG GAGACAGGTT GGCTGCTCTG ATCGTGGAGT 29760 CCAAAAGATG GCCTGCACTG AAAAGCCTCA TGAGTGTTGA CTTAGGGCTA GTCTAAGAGG 29820 TCCCTGGAAG AAGAAACACT CAGTAGGAGA GAAGCTGGAG GTACCTTCAG TGCTGAATTG 29880 GAACCTAGAT TCATTCCCCC GTGGAGCAAA TTACATAGGA AAGATGCCCA GTGATGGAGA 29940 GTGGGGGTGT CTCTAACAAT TACCCACCCA CCTGCCCCCA CCCCTAAGAA AAAGAAAATC 30000 ACATACAACC AGTCAGCTGT AAACATATGC CGAGCCTAGT AAACTCAGAT ACTAAGTTAC 30060 CAGGGTACCT GGCAAGTAAG AACATTCCTG ATTCCCTTCC CTCCTCTTCC TCTTTGCCCT 30120 CCAACCTTAG TGGCTAGCAA GATGGGGAGA GGAGGAGAAG CTGTAAGTGG GGAAAAAAGA 30180 GCAGCTTTCT CTCCTTTTCA GCTGCTGGAT TCTCCCTCAT CATAGGCCTG AGCTGGGGAA 30240 TCAGGAAGAA GGATTCTTTT TAAAACTGAA GTAACGTTAT CATTTAATTT TAAAACATTT 30300 TAAATTTTGA CAATGTTGAG ATTAGATATA CTAATTATTA AACTAAGATT ATGTTTTGCA 30360 GCTTGAAGTG ATAAGAAAAA CCTCTTATCT AAGAGCATCC AGGAAAGTCG GGGGTTTCCT 30420 GAACATCCTT TTAAATCCTT TGGAAGTCAG CTTTCAGAGA GGATTTAAAG TGTAGACTGG 30480 GCCTTCAGAA ACTTGGTTAA TGTAGGGGTT TCCTATGCAG ACTTGGGGAC TATACCTTGT 30540 GTGGAAGAGA GAAAATAAGA TTATCTTACA TTTTTCCCAT TCCTTTTTCA AAAAGAAAGC 30600 TCAGCTAGCA TGAAAGTTAA ATTCAAAACG TAATGGGTAT TATTTGCATA TTCAAATCTA 30660 GTGCATATCA TGTAAGTACT GAATTATGGT ATTCATTATT TCAAATGACA AGCTGGATTT 30720 TTTTTTCTTT CGAATTTCAC AAATTAATTT TCCTTGGAAC CTTTTGGTTT GGGCTTTAAG 30780 AGTTTAGGCT TTCATCACAA AGAGAGGACA GCCTTGAAGA TTAAAGTGTG TGGCTCTTCT 30840 CAAGATGTTC TTAGTCCAGC AAAGGATTCT ATGCATATTT GGGCTTCCTT CTGTCTCATA 30900 ACCTGTATTT CTTGATATTC TATTTATATT CTGTAAGATT TTTTTTTTAA AGGAAAAATT 30960 CTTCCATGGT TGAAGGACAT GTCAAAAATA GAGGATACAG TTTTATATCA AAGGAAGTTT 31020 CATGATATGA CTGTAGAAGC TCATTTGACT TAAGACACAT CATTTCCTCA TGGAAGTGTT 31080 AAACAGATCT GTACAATAAG GTTGGCAATC TTTGTGTAAA ACAGTTTTTT TTCTCCTGCT 31140 CTAAAGAAAG TGTATATTTC AAAATGTGAA TGTCAGCAGT CAGAAAATAG TATTTTTTTA 31200 ACTTCGTTTT CAAAGTCCTC AAAAACCTGT ACCTAATCAT GAATTTTTTT TCCCACAGAT 31260 TGTTTCTTCT TCTCCCTCCC AGAAACTTTG AAGTTTTTCT ACATGACACC AGGACCTATG 31320 TCTTTTTTTA ATTACACAGA AATGAAAGAA AAAAAGTGTG TTGTATCGTT AACCAAATAT 31380 ATGAAATCTT TAAGCTGTAT TTTTATTTTT AACTTTGTTT TGCAAAGAGG CCATTCCCTT 31440 TGGTTAAATA ATTTGTTATT CACAGTTTCC TTGTCCTCAT ATTATCAAGG GGAAAATTGT 31500 AGAAATTTTA AAGGAAGCTC TAGGCAATGT TTTCATCCCT GAATCTTTGG AGAGTTATAA 31560 AAACAAACAG ATTACTGAAC CTGTAAGAGA ACCAATCGTG AAGTCATTAC ATCTAAGCAT 31620 AAGCAAAATC TCCTCTTGGA TCATTAAGTT ATAGAAGAAA AGAAAGCCTG CACTTTGAAA 31680 TTTAAATAAA GCTTGGTAAC TTGTAAGTCA AACACGTAAA ATTTTACAAT TCAGGAATAT 31740 CGATAGCAGT TGAGTTTAAT AGACTTCTCA CATTCCAAAT TTAAAGCTTC CTTCTCTGTG 31800 CTAATAGAGA TACAATAGCA GTAGGCGTTT AAGAAGAATG AATCAACAAT TTAAAACTAT 31860 AATGTGTTTT TTATTCATCT CCCTTATTCA CATATATTTG TTTTGTTTTG AGAAGGAGTT 31920 CTGCTCTGTC GCCCAGGCAG GAGTGCTGTG GCACGATCTC AGCTCACCGC AACCTCTGCC 31980 TCCCGGGTTC AAGCGATTCT CTTGCCTCAG CCTCCTGAGT AGCTGCGATT ACAGGCGTGC 32040 GCCAGCAACC CCGGCTAATT TTTGTATTTT TAGTAGAGAC AGGGTTTCAC CACGTTGGCC 32100 AGGTTGGTCT CGAACCCCTG ATCTCAAGTG ATCAGCCCGC CTCGGCCTCC CAAAGTGCTG 32160 GGATTACAGG CGTGAGCCAT CACTTCTGGC CCTTATTCGC ATACAATTTA AAAATCATCA 32220 CAGAAGGTTT GAAAGAAGGA AGGGGCAGAA AATTACCTAC TTTTCCTCTC CCCAGCGATC 32280 TCCTTCAAAT CTGTGCCTTT TCCTCAGGCC CAGGCCTCAA TTTACTGAGC AGTCACACCT 32340 CACAGAGGGA GGTCTGGGCA ATCCACTCTT GGTCACAGGA AAGCCATTGA CCCTCCCACT 32400 TCCTCTCCTC CACCTTGTTC TCAACTCTTG ACTTTGGGCT TTGTTTCTGT TCAAGTCCTA 32460 GGAACTGGTT TCTTTTATCA GGTTAAGTGA TTAGTTCTCT TTCCCTCTAG TTGCTCTCAC 32520 TCCCTGACTC TTGCCTTCTG TAACAACTGG AGACAACTCT TTCAAAACCA GCTCCAAGCC 32580 CCAGACTTCT CTCTGGGCTT TAGTTCGTAA GGCAGGTGCC CTACTGAGTG AGCCTAGATC 32640 AGACAGAAAC ATAGCTGTTG GCAATGATTT AGGTGAATTT CCTTCCATTG TTTTTCTAAT 32700 ACCTTCTTTT TTTTGTAAAT ATAACCATGC ACATACACAC ATATTTGAAT ATCCTGCCTT 32760 TTTATTTAAA ATGACAATAG GTCCGGGAGT GGTGGCTCAT GCCTGTAATC CCAGCACTTT 32820 GGGAGGCCGA GGTGGGCAAT CACCTGAGGT CAGGAGTTCG AGACCAGCCT GGCCAACATG 32880 GTGAAACTCC ATCTCTACTA AAAATCAAAA ATTAGCCGGG CATGGTGGCA GGCTCCCAGC 32940 TACTCAGGAG GCTGAGATGT GAAAATCGCT TGAACCCGGG AGGTAGAGGT TGCAGTGAGC 33000 TGAGATCTTG CCATTGCACT CCAACCTGGG CAATAAGAGC GAAACTCCAT CTCATGGAAA 33060 AAAA AAAA AAAGACAGGA TAAACATTCT AGATAGTCTC TATAATGGTC ATGATTAAGA 33120 CAATAAAATA GTCTGAAATT GTCAATATAT ATTAATAATA ATTTATTTGG CCATTCTGCC 33180 AAGTAGCAGA CACCTGTCAT TCTGCCCACT CAGCACCTCT CTTTCTTTTA GGGAAATGCT 33240 ACCCACTCTT TGCATGGGTT CTGGATGGAA CTGTTGATCA CAGTGTTTTC ACTCCCCATT 33300 TTGCCTCACC AGAGGTAGAC AGAAGACCCA AGCCAGGCCA GTTACACACA ATCTTCAGAT 33360 AATTACCGTA TTGATCACAG TATCACCCCA CTCAAGGCTT GGTTGGAGAT GAGCAGAAGA 33420 GACTAAAGCT GGGTCATTTT AATTAACACC TGTACCCCAA AGAAAGACTG TCAATGAGGC 33480 TTTTATACCG ACACTCCTGG TTTCCATTCT TCCTGATGCC ATTCATTTGA CGAACTACCC 33540 AATCTTTCCA ACAGTGTCTT TGGAAGAAAG ATAGTCAGAA AAGAAGATAG AGTTGTTTTC 33600 TGTTCTTTGC AACCAAGGAA CTCTAAATGA TAGACTTGTT GCTAGGCACT TTGGTTATTT 33660 TTATTATCTT GAATACTTCT GTGATATACT TCTTTGTGCA TGCCTGTTTG TACGGATGTA 33720 GCTTTTTATA TATTTTATAT AATTTCTCAG AAGTGGAATT ACTTAGTCAA AAGGTATGAA 33780 CATTTTTCTG ATTCTTAATA TAAATTGTGC AAATGCTTTT TAAGAGGATT ATACCAGTTT 33840 ACATTTTGTG TTATATATAA CAGAAAGTAC TACTGAAAAA ATATTACAAA AATTTGTCTC 33900 TCTGTTCAGG AGGACCTTGT AATAGATGAT AAAGTACTTG AAATAGGAAC ATAGAGCATT 33960 TTCAGTTTAA AATAATTTCA TTGGGTTATT TACGGAATCC TTAGAATTAT GGCCAGACAT 34020 TTATAGATGA TCTGTACCAA ACCTAGGTTG GTTACATAAA TTGCTTATTC AACTGGCTTA 34080 AATCTATAAT AGAAAGATGA CACTTACTGA ATGTTTAATA TACACTTTGT CAGGGGCTTT 34140 GTATTATTCT ATGACATCTT CAAAATGACC CTACTTTCCT ATTTTATAAG TAAGGACAGG 34200 AAGGCTTCAA GAACATGACT AATTTTCCCA AGGGCTGTAC CAAAGCCAGA ACCCAAATCT 34260 ATAAGGCTTT TAAACCTGCA TTCTAAAACT GCATCTCGGC CATCTTATTC CTACAGAACT 34320 TAAGGTTAGA AAGCCAGATT GGAGTCCCAA TTTCACCACT TAGTAACCAG ACAAACTTGA 34380 GGAATTCACT CAACGTCTTT GAATCTTCAT TTTCTAATCT TTAAAACTAA AACAATAATA 34440 CTTGCTCTAC CTATGTCCTA AGATTTCGTG AGGCACATAG AGATAGTGTG GAAGAGTGCT 34500 GTACAGATGT CAAGTGTTAG CGTGATTACT TAGATCCCTG AACACCATGG ATGAATGTCT 34560 CTGACTGCTA TTAGAGGTCA TAAAGAATAT TGGGGCCAGG TACATTGGCT TATTCCTATA 34620 ATGCCAGCAC TTTGGGAGCC TGAGACAGGA GGATCACTCG AGGCCACGAG TTCAAGACCG 34680 GCCTGGGCAA CATAGTGAGA CCCCTTCTCT ACAAA AAA AAGCAGCCAC GTGTAGTGGC 34740 ACACACCTGT AGTCCCACAT ACTCAGGAGG GTGAGTTGGG AGGATAACTT TAGTCCAGGA 34800 GTTTCAAGGT GCAGTGAGCT GTGATTGCAC CACTGTACTC TAACCTGGAC AGCAGAGTGA 34860 GACCCTGTCT CTAAAAAAAA AGAAAAAAAA ATAATAATAA TAAAGAATAA TGGGGCCTTG 34920 GGATACCCAC TCCTCTCTTT CTGCTCTGAG TTGTGAAGCA GTTGAGTTAC ATATGCATGT 34980 CCAATGGATG AGGTTGAAAA TATCAACTGG ATTGGAATGT GGCTTACTTG CGTGGCCACA 35040 ATGAGCTTCG TAACACTTCC TGACAGGGTG AGAAGACAAA CTTCCTCACC CAGTCACTGG 35100 CAGAGCTGGA CACTCTGTGT CTCTCCCACA GAACAACCTC TTACTGCATG GAGGTGGATG 35160 AAAAAGTCAA CCGAGAACAG GCTACTCCAA AAAGCAGAGC ACCAAAGGCA CCAGCTGGTC 35220 AGGTCCCCCT TCCTAAGTAA ACAATCACGT AATTCATTCG GGACAAAGCC AGAGAGGTGG 35280 TGTGGAGAAA GAGAGGGCAG TTTCCTCCCA AGTTTTTCCT GGAATTCTTT ATGGGAATAT 35340 GAGGTTTAGG GGAATAAGAC TTCCCTTTAA CAGTGAAGAA TCCCCAGCTC TATTGGTAAT 35400 AGGAAATCGC TTACAAGGAT CATGGGGAGT ATTTCCTCAG CTCGTTCTGC CTCCTACTTG 35460 GCTGAGTGGA ATGGAACCAT CTGTGGCTGC TGCATATGAT ATTGTCAACT TTGTCATTCC 35520 ACACCCACTC CTTGACGCCC TACCATGTGG TCATAAGACT CCCTTTAAAG TGTTCCTTTA 35580 AAAAACAAAA TGTGTTTTGT TTCTATAAAA TACAGCTCAA TGTCAGAACC CTTGTCTTGT 35640 TTGCTCTCTG ATGTAACCCT TTCACAATGT TTGGGCAGCT TATTCTCTCT ATTTCCCTGT 35700 AGGGTCCCAT CCAGGCCAAA GTGAGTGCCA GCCTCATTTG GGCAGCAGAT GCCCTGTGGA 35760 AGGGCAGGAG GAGACGAGAG CTAATTGTAA CTTTGTGATT AGCTGTCATG GATGCCTGGT 35820 CCTGTCAATA GCGCTCAATA AAGCCAGAAG GCCAAGCGTT CGCTTCTGCA TACTGATTGC 35880 TGAGTCAGAT TTCTCAGTGC AGAAGGGCTT TCTAGGCAGT CAATTTTAGA ATATTAGTCT 35940 TGGTTCTTAA GTGGTTAAA TCCCTAGCTG GTCTTTAATC TGAGCCTGGA GAATTTAGTT 36000 ATGGCTGACA TTCTGCTGTG ATATTTTTGC CCTCAATATA TATGTCTTTC CTCCATCTCT 36060 TAGATCCCTG AATCATAGAG ATATATATGT TATATAATCA ACTGTCTCCA GTCTCTAAGA 36120 GTGATAAGTA CACATTGTGT CAGGTTGAGG GGACAGGAGA ACTTTCAAAA GCCTTTCTTG 36180 CCCCTTTTTC CTTCTCACTG CCTCCCACTA AGTCCAGCCA CTTATTATTC AGCTGACACT 36240 ATCATCATGA CCATGAGGTC TTTTGGGGCT ACCCTGGTTC GGATCCTTCT GGAGGTTTGT 36300 TGCTTAACTC TGTCTTCAGT CCTATGAGCT GCTTTTTCAA TAAGTTTCTA TTTTGGCTAA 36360 AGTTGGCCAG AATCTCCTTG TAACCAAAGA ACAAATAAAA TACCAGCTTG CAATGTTCTA 36420 TGTTGCTTCC ACCAAACTTA TGCAGCACTT CCTATCTAAT CCACCTACTA GTCTTTTTTT 36480 TTTTTATTTT TTTTGAGACG GAGTCTCGCT CTGTTGCTCA GGATGGAGTG CAATGGTGCA 36540 ATCTCGGCTC ACTGCAACCT CTGCCTCCCG GGTTCAAGCA ATTCCCCGGC CTCAGCCTCC 36600 TGAGTAGCTG GGACTACAGG TGCATGCCAC CACGTCCGGC TAATTTTTGT ATTTTAGGAG 36660 AGAGAGGGTT TCACCATGTT GCCCAGGCTG GTCACGAACT CCTGAGCTCA GGCAATCCGC 36720 CCTCCTCGGG CTCCCAAAGT GCTGGGATTA CAGGAGTGAG CCACCTCACC TGGCCCCGAC 36780 CTACTAGTCT TTAGTGTTTG CTTCCTTCTA TTGGGTAATT GTCTGTTTAT ATGCATGTCT 36840 TGTTTCCTCA AATAAAATGT GGTCTTCTCA AGGGTATTGG CCCATGTTCT ATCCATCTGT 36900 AGATATCACA GCACCTAGCA GTGTCTTTCA CAGAGGAAGT ACACAACTGG CATTATTGAT 36960 TCATTGCTCC ATTTTTTCCT TCTTTATCCC CAGCATTTCT CAATAATTTC AAACATCTCC 37020 ATTGGAGTAC CGGAGAAAGC AGGTAGCTTT ACTTGCAGCT ATGTTTCTAT CCCCATAGTA 37080 ACTAAAAGAG GACCCAGAGA AACATGTTTA AATGCTGTCC TGTTATCAGG ACCTCAGCCT 37140 TCTGATGCTC CGTGGCTTGG GGGTTATTGC TTGATCATCT CCTCCCCAAC CTACACTGTG 37200 TACCTATGCT AGTCTCTTCA TGAGGACTAA GCCCCATAGT AAAAGGGCTA GATAAATAGA 37260 AAATCATTTT ATGTAATTAT AAGAATGAGA ATACTGAGTA TTCTGGTGTT TGTTTAGGAT 37320 AAGCACATCT TTATTTGTAT GAGAAAAAGA AAAAGAGAGT GAAAAATATA TTAACGTGCA 37380 TATTGTTCAG AACCCTTGGA TTGCAAGTGA CAGAAACTCA ATTCAAACCA ACGTAAGTCA 37440 AAAGGAAAAT ATATTGGCTC ATGTAACCTT CTCACAGAGA GGGCAGGATG GAAGGGGCTT 37500 TGGGAACAAG AGAATTGTTC TCAAATTCTA GGAATACTAG GATTAGTCCA GGATGGGTCA 37560 CCTTCCTGTC CCTGAGGTGG TGGTAGCGAT GGTAGAGTCT TATGGGAGGA AAGAGTGCAT 37620 GTTAGGATGA AGGTAGGGCT AAGCAAACAA GGGCAAGGGC CACTATATCA TGCTAAAAAT 37680 GGTTTTTTTT GATGTCTTCC TTAATTTCAC AAATGCTTCC AACAAAGTAG CACACAGGAA 37740 AAAGAACATA GGGACTCTAC TGGTGGGTGC TTTTATCTTA AGCCTTGTAC TTGCTTTTCA 37800 CAGCTTACTC ACTGCTTGTA CCTGAGGCCA TATGCCCTGT AAAAGCTTCT GCAGGGTTTC 37860 TACTAAGCTG GGTTCCTTAT ATGGCTCTCT CCCATTTCTG TTGCCTCACT CTAGTGATCT 37920 TTCTCTTTTC CTCACCTCTG GGACTGGTGG CTGTTTGTAT GGACTGCCTT AGCTTTGCTT 37980 TGGGTTTTTT CCTGGGGACA ATGTCTTCAG ATTATCCTAG ACCAAATAAA CTACAGCCAC 38040 TGGGCCAGGC TCTTCCTCCT CCAACTGGAC CATGTTCCCA GGGCTCTTCA CCTTAGTTTA 38100 GGTCAAGCAT TCTTGGCAAA AGAAAGGCCT AGTTAACAAT AGACATTCTA GCAATTGATT 38160 CTTTTTGACA TGTTGTAAGA TCTATTCACA TTTTGTAATT AAAGCATTCC CCTATGGAAA 38220 CCAACACGAA CTAAGCTGCT CCTGGAATGC AGGGTGGCCT CCTCAATACA GGATGTTCTA 38280 GAGAGCTGTA TTTTGGGCAC TTAACTATTC TCCACTACTT AGGGCACAGC ACTGAAATTA 38340 ACACCACTAA GTTTGTCATG TCCATGTAGT TAGTCTCAGG CAGTGCAGCC TCAGGAGTGG 38400 AACTGACCTC TTATGTGTGT CCAGCCTTTC TTCCTTCAGA AGTCAGCTGT GTTTTCTGCT 38460 GACTCTCCAT AGGAACATCA GTCCTGAATC CTCAGACCAC CATCTGGAGT AGTAAGTGCT 38520 CCTGACAGTC CTAGAAGTTG TCTACCGCTG GATCTCCAAA GCGTGTGACA CACCGTGAGA 38580 GAGAAATGAG AAAGCTGGGC TCTTCAGGTA AATCTTGCTT TTTCACAAGC CCCCTAATTT 38640 TACTGCATAA TTATTTTGAA TTCACTGATA ATTTCTACAA TTTTCCCATA AGTCATCTAC 38700 ACACAATACC CTCTCATGCA ACACTTGGCT TTGCTAATAC ATATCTATTA TGAGAGCTGT 38760 GCTTCTTAAG CGTAAATGTT TTATATGCAC TAAGGCTCTT GGCTTACATA TAAAAGGGGT 38820 ATTGAGCAAT GTGATACAGA AGTCTTTTCT CCACAGGTCT CATATGTAAA GAATTCATTA 38880 GATTGGCTGA AATAGACTGA TCTGTCCATT TCTCTGCTCA CTTATCATAA GGAAGTCATT 38940 AGCTAAGGAA CAAAAACTAC AATCTATGTA ATTAGAAGAA CAAGCTGGTT TTGCTCAATA 39000 TAAAAATAAG AAAAAGAAAC CATGTGAAAG TCAAAATATT TGTTTAATCA GGTCATTGAG 39060 AATCTATTAA AAAGTATTTG AATTCTTTAT GATGAGAACT ATCTTGACTC AAGTGGACAG 39120 TGGTGAGCTT TTTGGCCTGT GGTCCCTACG TAGAAAGGAG GCTTTGTCAT AAAGTCTTAT 39180 ATGGTACAGG TGCCAAGTTA AGTGCCCAAG CTTGCTCTTA AAAGCATACT GGATTTTG 39238 (2) INFORMATION FOR SEQ ID NO:5: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 5596 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:5: TATGGACATA TTGTCGTTAG AACGCGGCTA CAATTAATAC ATAACCTTAT GTATCATACA 60 CATACGATTT AGGTGACACT ATAGAACCAG ATCTGATATC GAATGAATTC TTTCTTGCAA 120 GAGATCCAAG AACTCTCTCT TGGGGTCTGG ATCAGGACCT CTTTCCAGTA ACAATAGTAG 180 TAAGGGGTCA GGGAGACTGG ACAAAGGAGT TTAAGAAGCC TTAGATAAAG GGTCCTCATC 240 ATTGTCATAA CATAAAATCA TGGACTCCTA GAATTTTATA GCTGATAGGA TTAGAAATTT 300 CAAAATTCAA TTTCATTAAT TTTCATCTGC GAAAACAGAT GGCCAGAGAG GCCAAACAAT 360 TTGTTAAGGA GCACTGAGGG CAGACCACAC TGGAACGCAA ACCTCTTAGC AGAGTATACA 420 AGGCCTTTGA TCTCCTCAGT CAGAATGAAC TAGAGCTTTC CAGGGTACCC TTTCTGACTG 480 TTTAGCATGT TTGCCAGTCT GACTAATTTT GAAGTTGCTT AAATATCTGT CATTTCCACT 540 GTATCATAAT CTCCTCATTC ATCTTCAATC TCCAATGCCT TGAACTCAGT AAATGTTART 600 TGAACAAAAG TAAATTGAAC CCAGAATTTC TGATCATAAT CTGGAGCACT TTAAAATTGT 660 CAGCTTACTG GGAAACGGGA TAACATGTGA TTTGTCTTTG ATTTTTTTTT TCTCATATGC 720 TTTTTCCACC TATAGATGCT ACACGAATGT TTTTAAAATC TGATATAAA ATTAAAATTA 780 AAARATTAAA AAAAGAAAAT TTGATACAAT GCTACATTTA GAGTGTTGTG ATTAGATTCC 840 TTAAGTGTAT CATGGTGATC TCTACATCAC GTGGTGATCA AATTGCTTTG GGTTTTAACA 900 CATAACTGAC AAAGGCTTGG GGACATGTAA GATCCCAAAT ACATTTTTAT TGATTTTTTT 960 TTCTKGTTTG TCCTCTTTTA AATAACTTTT TTTTGTTATA AGAATAATTC ATGTTCAGTG 1020 GAGAAACCAT AGAAAATAGT GACAAGTGAA GGAATAAATT TAAAATGACC CATAATTGTA 1080 CCATACATTC TGATTTTTTA AACGCTGAAC AAATTAGCCT TGGGTAAGTA CCAGGAATAG 1140 AGTGCAGCAT TGAAAGTTAA AGTTTGGGGA AGGATAGCTG ACTTAAGAAA TTATCTAGTT 1200 AGACATTTTT TGGATGGGGT AATTTTGCAG ATGACATTAG TGAGAGAAAG GACTTGCCAC 1260 TCTCACACAG CTAGTAGGGG TGTGGGAGGA TATTGGAACC AAGTTTCAAG TCTTCAGTGA 1320 AGAATCAAGG GAGAAGTTCT AAAACCTAAC AATATCCCTC TGGATGGACA TTTATTTTAT 1380 TACTACAATA AGCCACACGG TGAGTCATAA GGAGCATTTC ATTCTTCTAA TATGTCTCTA 1440 CTGTATTTAG AATCTGATAA AGCCCCTATT AGAATTCATC TCTTTAAGAA TAAAAGAAGC 1500 TGAGGAACTA AAGAGAGGGT TGGAATAATC CACTAATTAT ATCCGTTAAG CTTCAGTTAC 1560 GCTAATAAGG AATATCACAT GACTGTGGTG TGTGCTTGTT CTGAACAGTA AAGTACATGA 1620 GGAAAGATAA GATTCAGGGC TGAAATGTCC TTCAGCATAT GTAGGTAGTG GTGATGAAAG 1680 TCATTAAAAG AAAAATTGAT TGAGGTATTT TAGTAAACAA AAGAACTCAC CACTTACCCA 1740 TCAGGAAGTG TATTGTTAAT GCAGTGCTGT TCAGCCTTCT GGAAGAAAAG GTTTCTTCAT 1800 GCTTCTCTCT TTAGCCTAAT TCTTATCCTG TCACTTTTCA GGCAAAATTA AMAAAAAAAA 1860 AAGATTGAAA ACGATGCTCC TATTTTATTT GCTTCAAAAG AAACAGGCTG TTGCATTGTG 1920 CTTGGAACAG TTTACTCTTG GCCTTGATGT AAGTGTGAAA GGAAGCCCAT GTAATTGACT 1980 AGGCAGTATC TGAAGAAGCA GGAAATACAG TGTTAAGAAA ATGAACAGGC ATGAAAACCA 2040 TGGCTATTTG ATAAAAGTAA ATAATTTCTG CAGTTCACAT GTTCTCAGCA TATTTTCTTT 2100 GATACTGACT TGCTTAATAT GACAATAGCA GAACCATGGT AGCTTGTAGG CATTACTTTT 2160 CTTTTAATTT CTTTTACATT TTGAATTTAC CAGCACTCAC ATTTGTATTA CTTTTGGGTT 2220 ATACTGAGGA TCTATAACTT ATAGATCAAA TACCTGACAT ATATATGCAT TCTCTGAAGT 2280 CTTAGGGCAG AACTAGAACA TTCTTGTGAA CATCAGTATA AGATATTAAA ATGGAAGTTT 2340 TGCCTAAGAC TGAAGACAAT AAAAATATCA TAGTCTGAAA TGAATGCCAG CACACCATAC 2400 AGGATTTAAA TATCTATACA TATATATGTG TGTGTATTAT ATATATTTAA TATATATCTG 2460 TGTGGGATAG GAAGAGGTAG GGGGAAATCA GTTTTACAAT TATTAAGTAT TTCACCCTTG 2520 ACAAGAGTAT ATATATTGGA AATCAGTTGG AGAGTATTTT CAAAGATAAA TGTTAGTGTG 2580 CTATGAATGA ATCCACCCCT ACCACCACTG AGGCAGGGTA GGAGAGGCCT GTGCTCCTCA 2640 AGCATAGTTG GAAAAGGACC TCAACAAGAC CACTTCAAGA GTCTAATGTG TGGAGACTGT 2700 TGCTTAGGGA GACCTTATGG TCTAGCTTCT GACTCACAGC TAAGTCAGGG AGACAGGTTG 2760 GCTGCTCTGA TCGTGGAGTC CAAAAGATGG CCTGCACTGA AAAGCCTCAT GAGTGTTGAC 2820 TTAGGGCTAG TCTAAGAGGT CCCTGGAAGA AGAAACACTC AGTAGGAGAG AAGCTGGAGG 2880 TACCTTCAGT GCTGAATTGG AACCTAGATT CATTCCCCCG TGGAGCAAAT TACATAGGAA 2940 AGATGCCCAG TGATGGAGAG TGGGGGTGTC TCTAACAATT ACCCACCCAC CTGCCCCCAC 3000 CCCTAAGAAA AAGAAAATCA CATACAACCA GTCAGCTGTA AACATATGCC GAGCCTAGTA 3060 AACTCAGATA CTAAGTTACC AGGGTACCTG GCAAGTAAGA ACATTCCTGA TTCCCTTCCC 3120 TCCTCTTCCT CTTTGCCCTC CAACCTTAGT GGCTAGCAAG ATGGGGAGAG GAGGAGAAGC 3180 TGTAAGTGGG GAAAAAAGAG CAGCTTTCTC TCCTTTTCAG CTGCTGGATT CTCCCTCATC 3240 ATAGGCCTGA GCTGGGGAAT CAGGAAGAAG GATTCTTTTT AAAACTGAAG TAACGTTATC 3300 ATTTAATTTT AAAACATTTT AAATTTTGAC AATGTTGAGA TTAGATATAC TAATTATTAA 3360 ACTAAGATTA TGTTTTGCAG CTTGAAGTGA TAAGAAAAAC CTCTTATCTA AGAGCATCCA 3420 GGAAAGTCGG GGGTTTCCTG AACATCCTTT TAAATCCTTT GGAAGTCAGC TTTCAGAGAG 3480 GATTTAAAGT GTAGACTGGG CCTTCAGAAA CTTGGTTAAT GTAGGGGTTT CCTATGCAGA 3540 CTTGGGGACT ATACCTTGTG TGGAAGAGAG AAAATAAGAT TATCTTACAT TTTTCCCATT 3600 CCTTTTTCAA AAAGAAAGCT CAGCTAGCAT GAAAGTTAAA TTCAAAACGT AATGGGTATT 3660 ATTTGCATAT TCAAATCTAG TGCATATCAT GTAAGTACTG AATTATGGTA TTCATTATTT 3720 CAAATGACAA GCTGGATTTT TTTTTCTTTC GAATTTCACA AATTAATTTT CCTTGGAACC 3780 TTTTGGTTTG GGCTTTAAGA GTTTAGGCTT TCATCACAAA GAGAGGACAG CCTTGAAGAT 3840 TAAAGTGTGT GGCTCTTCTC AAGATGTTCT TAGTCCAGCA AAGGATTCTA TGCATATTTG 3900 GGCTTCCTTC TGTCTCATAA CCTGTATTTC TTGATATTCT ATTTATATTC TGTAAGATTT 3960 TTTTTTTAAA GGAAAAATTC TTCCATGGTT GAAGGACATG TCAAAAATAG AGGATACAGT 4020 TTTATATCAA AGGAAGTTTC ATGATATGAC TGTAGAAGCT CATTTGACTT AAGACACATC 4080 ATTTCCTCAT GGAAGTGTTA AACAGATCTG TACAATAAGG TTGGCAATCT TTGTGTAAAA 4140 CAGTTTTTTT TCTCCTGCTC TAAAGAAAGT GTATATTTCA AAATGTGAAT GTCAGCAGTC 4200 AGAAAATAGT ATTTTTTTAA CTTCGTTTTC AAAGTCCTCA AAAACCTGTA CCTAATCATG 4260 AATTTTTTTT CCCACAGATT GTTTCTTCTT CTCCCTCCCA GAAACTTTGA AGTTTTTCTA 4320 CATGACACCA GGACCTATGT CTTTTTTTAA TTACACAGAA ATGAAAGAAA AAAAGTGTGT 4380 TGTATCGTTA ACCAAATATA TGAAATCTTT AAGCTGTATT TTTATTTTTA ACTTTGTTTT 4440 GCAAAGAGGC CATTCCCTTT GGTTAAATAA TTTGTTATTC ACAGTTTCCT TGTCCTCATA 4500 TTATCAAGGG GAAAATTGTA GAAATTTTAA AGGAAGCTCT AGGCAATGTT TTCATCCCTG 4560 AATCTTTGGA GAGTTATAAA AACAAACAGA TTACTGAACC TGTAAGAGAA CCAATCGTGA 4620 AGTCATTACA TCTAAGCATA AGCAAAATCT CCTCTTGGAT CATTAAGTTA TAGAAGAAAA 4680 GAAAGCCTGC ACTTTGAAAT TTAAATAAAG CTTGGTAACT TGTAAGTCAA ACACGTAAAA 4740 TTTTACAATT CAGGAATATC GATAGCAGTT GAGTTTAATA GACTTCTCAC ATTCCAAATT 4800 TAAAGCTTCC TTCTCTGTGC TAATAGAGAT ACAATAGCAG TAGGCGTTTA AGAAGAATGA 4860 ATCAACAATT TAAAACTATA ATGTGTTTTT TATTCATCTC CCTTATTCAC ATATATTTGT 4920 TTTGTTTTGA GAAGGAGTTC TGCTCTGTCG CCCAGGCAGG AGTGCTGTGG CACGATCTCA 4980 GCTCACCGCA ACCTCTGCCT CCCGGGTTCA AGCGATTCTC TTGCCTCAGC CTCCTGAGTA 5040 GCTGCGATTA CAGGCGTGCG CCAGCAACCC CGGCTAATTT TTGTATTTTT AGTAGAGACA 5100 GGGTTTCACC ACGTTGGCCA GGTTGGTCTC GAACCCCTGA TCTCAAGTGA TCAGCCCGCC 5160 TCGGCCTCCC AAAGTGCTGG GATTACAGGC GTGAGCCATC ACTTCTGGCC CTTATTCGCA 5220 TACAATTTAA AAATCATCAC AGAAGGTTTG AAAGAAGGAA GGGGCAGAAA ATTACCTACT 5280 TTTCCTCTCC CCAGCGATCT CCTTCAAATC TGTGCCTTTT CCTCAGGCCC AGGCCTCAAT 5340 TTACTGAGCA GTCACACCTC ACAGAGGGAG GTCTGGGCAA TCCACTCTTG GTCACAGGAA 5400 AGCCATTGAC CCTCCCACTT CCTCTCCTCC ACCTTGTTCT CAACTCTTGA CTTTGGGCTT 5460 TGTTTCTGTT CAAGTCCTAG GAACTGGTTT CTTTTATCAG GTTAAGTGAT TAGTTCTCTT 5520 TCCCTCTAGT TGCTCTCACT CCCTGACTCG GGGGATCCAC TAGTTCTAGA GCGGCCGCCA 5580 CCGCGTGGAC TCACAG 5596 (2) INFORMATION FOR SEQ ID NO:6: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 18443 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:6: GAGGGCGGGA ACCCCCTTTC CAAAAAAAAA GAAACAAAGA CAGGATAAAC ATTCTAGATA 60 GTCTCTATAA TGGTCATGAT TAAGACAATA AAATAGTCTG AAATTGTCAA TATATATTAA 120 TAATAATTTA TTTGGCCATT CTGCCAAGTA GCAGACACCT GTCATTCTGC CCACTCAGCA 180 CCTCTCTTTC TTTTAGGGAA ATGCTACCCA CTCTTTGCAT GGGTTCTGGA TGGAACTGTT 240 GATCACAGTG TTTTCACTCC CCATTTTGCC TCACCAGAGG TAGACAGAAG ACCCAAGCCA 300 GGCCAGTTAC ACACAATCTT CAGATAATTA CCGTATTGAT CACAGTATCA CCCCACTCAA 360 GGCTTGGTTG GAGATGAGCA GAAGAGACTA AAGCTGGGTC ATTTTAATTA ACACCTGTAC 420 CCCAAAGAAA GACTGTCAAT GAGGCTTTTA TACCGACACT CCTGGTTTCC ATTCTTCCTG 480 ATGCCATTCA TTTGACGAAC TACCCAATCT TTCCAACAGT GTCTTTGGAA GAAAGATAGT 540 CAGAAAAGAA GATAGAGTTG TTTTCTGTTC TTTGCAACCA AGGAACTCTA AATGATAGAC 600 TTGTTGCTAG GCACTTTGGT TATTTTTATT ATCTTGAATA CTTCTGTGAT ATACTTCTTT 660 GTGCATGCCT GTTTGTACGG ATGTAGCTTT TTATATATTT TATATAATTT CTCAGAAGTG 720 GAATTACTTA GTCAAAAGGT ATGAACATTT TTCTGATTCT TAATATAAAT TGTGCAAATG 780 CTTTTTAAGA GGATTATACC AGTTTACATT TTGTGTTATA TATAACAGAA AGTACTACTG 840 AAAAAATATT ACAAAAATTT GTCTCTCTGT TCAGGAGGAC CTTGTAATAG ATGATAAAGT 900 ACTTGAAATA GGAACATAGA GCATTTTCAG TTTAAAATAA TTTCATTGGG TTATTTACGG 960 AATCCTTAGA ATTATGGCCA GACATTTATA GATGATCTGT ACCAAACCTA GGTTGGTTAC 1020 ATAAATTGCT TATTCAACTG GCTTAAATCT ATAATAGAAA GATGACACTT ACTGAATGTT 1080 TAATATACAC TTTGTCAGGG GCTTTGTATT ATTCTATGAC ATCTTCAAAA TGACCCTACT 1140 TTCCTATTTT ATAAGTAAGG ACAGGAAGGC TTCAAGAACA TGACTAATTT TCCCAAGGGC 1200 TGTACCAAAG CCAGAACCCA AATCTATAAG GCTTTTAAAC CTGCATTCTA AAACTGCATC 1260 TCGGCCATCT TATTCCTACA GAACTTAAGG TTAGAAAGCC AGATTGGAGT CCCAATTTCA 1320 CCACTTAGTA ACCAGACAAA CTTGAGGAAT TCACTCAACG TCTTTGAATC TTCATTTTCT 1380 AATCTTTAAA ACTAAAACAA TAATACTTGC TCTACCTATG TCCTAAGATT TCGTGAGGCA 1440 CATAGAGATA GTGTGGAAGA GTGCTGTACA GATGTCAAGT GTTAGCGTGA TTACTTAGAT 1500 CCCTGAACAC CATGGATGAA TGTCTCTGAC TGCTATTAGA GGTCATAAAG AATATTGGGG 1560 CCAGGTACAT TGGCTTATTC CTATAATGCC AGCACTTTGG GAGCCTGAGA CAGGAGGATC 1620 ACTCGAGGCC ACGAGTTCAA GACCGGCCTG GGCAACATAG TGAGACCCCT TCTCTACAAA 1680 AAAAAAAGCA GCCACGTGTA GTGGCACACA CCTGTAGTCC CACATACTCA GGAGGGTGAG 1740 TTGGGAGGAT AACTTTAGTC CAGGAGTTTC AAGGTGCAGT GAGCTGTGAT TGCACCACTG 1800 TACTCTAACC TGGACAGCAG AGTGAGACCC TGTCTCTAAA AAAAAAGAAA AAAAAATAAT 1860 AATAATAAAG AATAATGGGG CCTTGGGATA CCCACTCCTC TCTTTCTGCT CTGAGTTGTG 1920 AAGCAGTTGA GTTACATATG CATGTCCAAT GGATGAGGTT GAAAATATCA ACTGGATTGG 1980 AATGTGGCTT ACTTGCGTGG CCACAATGAG CTTCGTAACA CTTCCTGACA GGGTGAGAAG 2040 ACAAACTTCC TCACCCAGTC ACTGGCAGAG CTGGACACTC TGTGTCTCTC CCACAGAACA 2100 ACCTCTTACT GCATGGAGGT GGATGAAAAA GTCAACCGAG AACAGGCTAC TCCAAAAAGC 2160 AGAGCACCAA AGGCACCAGC TGGTCAGGTC CCCCTTCCTA AGTAAACAAT CACGTAATTC 2220 ATTCGGGACA AAGCCAGAGA GGTGGTGTGG AGAAAGAGAG GGCAGTTTCC TCCCAAGTTT 2280 TTCCTGGAAT TCTTTATGGG AATATGAGGT TTAGGGGAAT AAGACTTCCC TTTAACAGTG 2340 AAGAATCCCC AGCTCTATTG GTAATAGGAA ATCGCTTACA AGGATCATGG GGAGTATTTC 2400 CTCAGCTCGT TCTGCCTCCT ACTTGGCTGA GTGGAATGGA ACCATCTGTG GCTGCTGCAT 2460 ATGATATTGT CAACTTTGTC ATTCCACACC CACTCCTTGA CGCCCTACCA TGTGGTCATA 2520 AGACTCCCTT TAAAGTGTTC CTTTAAAAAA CAAAATGTGT TTTGTTTCTA TAAATACAG 2580 CTCAATGTCA GAACCCTTGT CTTGTTTGCT CTCTGATGTA ACCCTTTCAC AATGTTTGGG 2640 CAGCTTATTC TCTCTATTTC CCTGTAGGGT CCCATCCAGG CCAAAGTGAG TGCCAGCCTC 2700 ATTTGGGCAG CAGATGCCCT GTGGAAGGGC AGGAGGAGAC GAGAGCTAAT TGTAACTTTG 2760 TGATTAGCTG TCATGGATGC CTGGTCCTGT CAATAGCGCT CAATAAAGCC AGAAGGCCAA 2820 GCGTTCGCTT CTGCATACTG ATTGCTGAGT CAGATTTCTC AGTGCAGAAG GGCTTTCTAG 2880 GCAGTCAATT TTAGAATATT AGTCTTGGTT CTTAAGTGGT TAAAATCCCT AGCTGGTCTT 2940 TAATCTGAGC CTGGAGAATT TAGTTATGGC TGACATTCTG CTGTGATATT TTTGCCCTCA 3000 ATATATATGT CTTTCCTCCA TCTCTTAGAT CCCTGAATCA TAGAGATATA TATGTTATAT 3060 AATCAACTGT CTCCAGTCTC TAAGAGTGAT AAGTACACAT TGTGTCAGGT TGAGGGGACA 3120 GGAGAACTTT CAAAAGCCTT TCTTGCCCCT TTTTCCTTCT CACTGCCTCC CACTAAGTCC 3180 AGCCACTTAT TATTCAGCTG ACACTATCAT CATGACCATG AGGTCTTTTG GGGCTACCCT 3240 GGTTCGGATC CTTCTGGAGG TTTGTTGCTT AACTCTGTCT TCAGTCCTAT GAGCTGCTTT 3300 TTCAATAAGT TTCTATTTTG GCTAAAGTTG GCCAGAATCT CCTTGTAACC AAAGAACAAA 3360 TAAAATACCA GCTTGCAATG TTCTATGTTG CTTCCACCAA ACTTATGCAG CACTTCCTAT 3420 CTAATCCACC TACTAGTCTT TTTTTTTTTT ATTTTTTTTG AGACGGAGTC TCGCTCTGTT 3480 GCTCAGGATG GAGTGCAATG GTGCAATCTC GGCTCACTGC AACCTCTGCC TCCCGGGTTC 3540 AAGCAATTCC CCGGCCTCAG CCTCCTGAGT AGCTGGGACT ACAGGTGCAT GCCACCACGT 3600 CCGGCTAATT TTTGTATTTT AGGAGAGAGA GGGTTTCACC ATGTTGCCCA GGCTGGTCAC 3660 GAACTCCTGA GCTCAGGCAA TCCGCCCTCC TCGGGCTCCC AAAGTGCTGG GATTACAGGA 3720 GTGAGCCACC TCACCTGGCC CCGACCTACT AGTCTTTAGT GTTTGCTTCC TTCTATTGGG 3780 TAATTGTCTG TTTATATGCA TGTCTTGTTT CCTCAAATAA AATGTGGTCT TCTCAAGGGT 3840 ATTGGCCCAT GTTCTATCCA TCTGTAGATA TCACAGCACC TAGCAGTGTC TTTCACAGAG 3900 GAAGTACACA ACTGGCATTA TTGATTCATT GCTCCATTTT TTCCTTCTTT ATCCCCAGCA 3960 TTTCTCAATA ATTTCAAACA TCTCCATTGG AGTACCGGAG AAAGCAGGTA GCTTTACTTG 4020 CAGCTATGTT TCTATCCCCA TAGTAACTAA AAGAGGACCC AGAGAAACAT GTTTAAATGC 4080 TGTCCTGTTA TCAGGACCTC AGCCTTCTGA TGCTCCGTGG CTTGGGGGTT ATTGCTTGAT 4140 CATCTCCTCC CCAACCTACA CTGTGTACCT ATGCTAGTCT CTTCATGAGG ACTAAGCCCC 4200 ATAGTAAAAG GGCTAGATAA ATAGAAAATC ATTTTATGTA ATTATAAGAA TGAGAATACT 4260 GAGTATTCTG GTGTTTGTTT AGGATAAGCA CATCTTTATT TGTATGAGAA AAAGAAAAAG 4320 AGAGTGAAAA ATATATTAAC GTGCATATTG TTCAGAACCC TTGGATTGCA AGTGACAGAA 4380 ACTCAATTCA AACCAACGTA AGTCAAAAGG AAAATATATT GGCTCATGTA ACCTTCTCAC 4440 AGAGAGGGCA GGATGGAAGG GGCTTTGGGA ACAAGAGAAT TGTTCTCAAA TTCTAGGAAT 4500 ACTAGGATTA GTCCAGGATG GGTCACCTTC CTGTCCCTGA GGTGGTGGTA GCGATGGTAG 4560 AGTCTTATGG GAGGAAAGAG TGCATGTTAG GATGAAGGTA GGGCTAAGCA AACAAGGGCA 4620 AGGGCCACTA TATCATGCTA AAAATGGTTT TTTTTGATGT CTTCCTTAAT TTCACAAATG 4680 CTTCCAACAA AGTAGCACAC AGGAAAAAGA ACATAGGGAC TCTACTGGTG GGTGCTTTTA 4740 TCTTAAGCCT TGTACTTGCT TTTCACAGCT TACTCACTGC TTGTACCTGA GGCCATATGC 4800 CCTGTAAAAG CTTCTGCAGG GTTTCTACTA AGCTGGGTTC CTTATATGGC TCTCTCCCAT 4860 TTCTGTTGCC TCACTCTAGT GATCTTTCTC TTTTCCTCAC CTCTGGGACT GGTGGCTGTT 4920 TGTATGGACT GCCTTAGCTT TGCTTTGGGT TTTTTCCTGG GGACAATGTC TTCAGATTAT 4980 CCTAGACCAA ATAAACTACA GCCACTGGGC CAGGCTCTTC CTCCTCCAAC TGGACCATGT 5040 TCCCAGGGCT CTTCACCTTA GTTTAGGTCA AGCATTCTTG GCAAAAGAAA GGCCTAGTTA 5100 ACAATAGACA TTCTAGCAAT TGATTCTTTT TGACATGTTG TAAGATCTAT TCACATTTTG 5160 TAATTAAAGC ATTCCCCTAT GGAAACCAAC ACGAACTAAG CTGCTCCTGG AATGCAGGGT 5220 GGCCTCCTCA ATACAGGATG TTCTAGAGAG CTGTATTTTG GGCACTTAAC TATTCTCCAC 5280 TACTTAGGGC ACAGCACTGA AATTAACACC ACTAAGTTTG TCATGTCCAT GTAGTTAGTC 5340 TCAGGCAGTG CAGCCTCAGG AGTGGAACTG ACCTCTTATG TGTGTCCAGC CTTTCTTCCT 5400 TCAGAAGTCA GCTGTGTTTT CTGCTGACTC TCCATAGGAA CATCAGTCCT GAATCCTCAG 5460 ACCACCATCT GGAGTAGTAA GTGCTCCTGA CAGTCCTAGA AGTTGTCTAC CGCTGGATCT 5520 CCAAAGCGTG TGACACACCG TGAGAGAGAA ATGAGAAAGC TGGGCTCTTC AGGTAAATCT 5580 TGCTTTTTCA CAAGCCCCCT AATTTTACTG CATAATTATT TTGAATTCAC TGATAATTTC 5640 TACAATTTTC CCATAAGTCA TCTACACACA ATACCCTCTC ATGCAACACT TGGCTTTGCT 5700 AATACATATC TATTATGAGA GCTGTGCTTC TTAAGCGTAA ATGTTTTATA TGCACTAAGG 5760 CTCTTGGCTT ACATATAAAA GGGGTATTGA GCAATGTGAT ACAGAAGTCT TTTCTCCACA 5820 GGTCTCATAT GTAAAGAATT CATTAGATTG GCTGAAATAG ACTGATCTGT CCATTTCTCT 5880 GCTCACTTAT CATAAGGAAG TCATTAGCTA AGGAACAAAA ACTACAATCT ATGTAATTAG 5940 AAGAACAAGC TGGTTTTGCT CAATATAAAA ATAAGAAAAA GAAACCATGT GAAAGTCAAA 6000 ATATTTGTTT AATCAGGTCA TTGAGAATCT ATTAAAAAGT ATTTGAATTC TTTATGATGA 6060 GAACTATCTT GACTCAAGTG GACAGTGGTG AGCTTTTTGG CCTGTGGTCC CTACGTAGAA 6120 AGGAGGCTTT GTCATAAAGT CTTATATGGT ACAGGTGCCA AGTTAAGTGC CCAAGCTTGM 6180 TCTTAAAAGC ATACTGGATT TTGTTTTAGA CTTTTAGTGA ACTGAAGGGA ATAAACAAAT 6240 CCCTCTGGGA GAACTTCTCC TCCATCCTTG GTGAAGTCAT TCTGCCAGAA TTCTATCTGG 6300 TAGTTACCTT CTCCGATTCA TTAAATGTTG TCCCATGGTC CGACATGGGT AATTTTTCTC 6360 TCATTTGTGA TTAGTTCCAC TACAAGGAAT TAAATATTCA ACTTCTTGCC TTCTGGGATA 6420 TACTCAGCCT TATCACAGAG CTCCTCCAGG GAAGGAACTT AGATTCTTTG AAGAACTTCC 6480 CTGCTCTTAC CCAAACCGAT TCAGTTGTTA ATTCTGTCCA CCTTGCTCCA TTTTCAGTGC 6540 AGGAGAAAAA GCATTTGTGG CAAGTCTGAC CTTACAAAGG CTCGTTAATG CTCAATAACT 6600 GTGAGGACCT GCTATAAGTC ATGCCTTTTA AGAAAAAATA CACACATGCA CACACTCACG 6660 ACAAGACTGC AACACAACTG TGATGGCAGC TTGCATATTG AACCAGCTGT TTCCCTAAAA 6720 CATTTGATTC GGCATCCTTT GTAGACAGTA AATGCAAAAG ACTTAGGTTG GAAAAGTGCA 6780 TTAGGTTTTG ATTAACGATT GGATGAGGGC CAGTTAAATT TTTAAATCTG AATGAGCTTG 6840 CTGACTCAGG AGCCTTAGCA GCATAATGGA CAGACAGTCC TCAAAGCTTT CATTAAAAGG 6900 GTTTCTGGTA ACTGATGTCT ARAGAAATGA GTTGAAATAC AATTCACTGA ACCACTCAGC 6960 TTTCATCTAA AACAGAATAT GTAATCTCAA AGAACTCAAC TGGTCTCTTG AAATATTCAG 7020 GTAAAATTAA ATGTAAAGAA GCTAGAGCTT AAATATTTTG AGGAAAGGAA GCCTCCTGTA 7080 GCTTTGTGAC TATATCACTT TATCCTTTTG AATGCCGTAT TTAATTATGT TAATTGCATT 7140 TTAAGTATAG CTGGAGTCAC CGATCTGCTG AAAACAAACT CTASAATGGT TTGTGGGAGG 7200 TGCTCAGGAT GTATCAGAGA CTGATTTGAT TTGCATTTTA TTTTTAACTT TAGTTCCTCT 7260 CTGAACTCTG CCTTCTCATG TTTGTTTTTT WTGTTGTTGT TGCTTAATAC AGTCATGTGC 7320 CACCTAATGA CAGGGATATG TTCTGAGAAA TGCATTATTA GGTGATTTTG CCATTGTGCA 7380 AACATCACAG TGTACTTACA CAAACCTAGA TGGCATAGCC TACTACACAC GTCTGCTATA 7440 TGGTAGAGCC TATTGCTTCC AGACTACAAA CCTGTATAGC ATGTTACTGT ACTAACTACT 7500 GTAGGCAGTT GTAACACTGG TATTTGTGTA TCTAAACCTA TCTAAACATA GAAAAGGTAC 7560 AATAAAAATA CAGTATTATA ATCTTATGGG ACCACTGCTA TATATGCAGT CCATCATTGA 7620 CTGAAACATT ATGTGGTGCA TGACTATAAT AGGATCAAAC TATGCCTTTG CAGAAATCCC 7680 CCTGGAAAGC CTCTGAAACT ACCCTGATCT TAGAGGCAGT TTTATAAATC ACGGCCAATG 7740 ATTCTCAGCC TTTGGGTTGT GCCAGAGATG TGTCCGCTCT CCTTTTGCAA TGACCCTAGA 7800 GGTAAAGGTG CTCTTTCTTC TTCTGCTTCT CATGAAAAAA TGTAAATGTT GTATTTTAGC 7860 TTCTTTTCCC AGTCTAGTAA TATCTTGTTA AATTTACAAG ATTGTAGCGG TGCCTCCAAA 7920 AGGGGATAGC AATAGTTACT TTGAAAATGG GTGAGTTCTT TGCAACCATC TCTGAGTTGA 7980 ACAGTTCTTG TATAATCTGT CTTCCCAGTT AGGCTGTGAG CCGCCTGAAG GCAGCAAGTG 8040 TATCTTTCAC TCTTCTCTGA TCTCCTCAGC CACTCTTCTG CCCCACAATT CCAAAAATCA 8100 GTTACCAAGC CATTGTAATT CCTTTTCTGA AATGTGTAGT AGACTCCTTT TAGGGTATTT 8160 GCCCAGTTCA CAAAGACCCC TGCCCTCTTT GGAAATCTGT CCTTGCAGCC ATATATGGTT 8220 TTTGTTTGTT TGTTTGTTTG AGACAGAGTT TCACTCTGTC GCCCAGGCTG GAGTGCAGTG 8280 GTGCGATCTC GGCTCACTGC AAGCTCCCCC TCCCGGGTTC ACGCCATTCT CCTGCCTCAG 8340 CCTCCCAAGT AGCTGGGACT ACAGGCGCCT GCCACCATAC CCAGTTAATT TTTTTGTATT 8400 TTTAGTAGAG ACGGGCTTTC ACCATGTTAG CCAGGATGGT CTCGATCTCC TGACCTCGTG 8460 ATCTGCCCGC TTTGGCCTCC CAAAGTGCTG GGATTACAGG CGTGAGCCAC TGCACCCGGC 8520 AGCCATATAT GTTCTATATG ACTCTTTCTG AGACAATAGC TGATTAGAAC AGTGATTAGA 8580 ACTGTGATTT CTGAGACAAT AGCTGATTTC TGAGACAATA GCTGATTAGA ACAGTTGCCA 8640 CGAGCTGGAC CAATCATATT AATATTCTCT ATCTCTCTCT TTTGCTCTCG AAATCTCAAA 8700 TTGAGATTCA GAAACAGCTA TGTAGTCTCT GTTTGTGGCT AGAACTGTAA CATATGAACC 8760 CAGAGCTAGA GAGATGCAAT ATTCTATCAA GCAGAGAGAG AAGCAGAGGA AGCCGGTCGG 8820 CACAGACGGA ATGCAGTAGC ACACAGAGAG AAGCAGACAC TCGGAGATGT CTGACACCTT 8880 TCTGCTTAGA TTCCAGTCAG TTCAGAGGCC CAGACGCATT CCTGTCTGGA AGCATTCTGA 8940 TCCTGTTTTG TAAATCAACA ATAAATCCCT TGCCACCCTC TTTGCGTGTT AGCTTAAGTT 9000 GTCTTGCTCT TAAAAATCTA AAGAGTTCTA AATGATATGA AATGTCTGTT ATACAGAAAG 9060 TAGAATGACA ATTGCCAGGG GCTGAGAGGA GAGGGAAATG GAAAATTGCT CAATGGTTAT 9120 AGTTTTAGCT TTGCAAGAGG AAAAAGTTGT GGATATTGGT GGCACAACAA TGCGAATATA 9180 CTTACCACTA CTGAGCTCTA TGCTTAGATA CGGTTAAGAT GGTAAATTTT ATGTTATGTA 9240 TATTTTATCG CTGTTTTTAA AAAAGTTTAA AATAGCCTGT TGTAGTCAGC TTCCTTGTCT 9300 TCCTTACTAC TGCAGCCATA TTCAGGTCTC CATGGCCCAA GGTATGGACA ACTGTAGTCA 9360 CCAAACTGGT CTCCCCACTT CCACCCCTTG GAATTTGGTC CCCAGCAATC TACCCTACAT 9420 GCATGGAGCA ATCAATATTA CCCATAAAGC ACTAACGCTG TGCTGTACTC CAAAATGCAA 9480 ACCTTCATGG TGTCCCATTG AATTCAGGAT CAAGTTCATA CTCCCCAGCT TGTCATACAG 9540 GACCCAGTGA TCCTTTCCAA CCTTCTGACC TACTGATTCC CAGTAGGAAG CAAACCCTAG 9600 CAAGACTGGT CTGCCTCATC CCAGAACAGT ACTTACTCAT GCTGTTTCCT TGCCATGATT 9660 ACCTTCCTTC TCCTCACCAC ATCTTATCTT TCTTTCACTT GATCTTAGTC CAAATGCCGA 9720 GAAGCAATCT TATCTTACTT TCAAAGCCCA GGTTCAGACC CATCAATTCT ATAAAACATT 9780 TCTGACCACA CTAGTCCTCC ATGGACATTT ATTTGAATTG AACTTCTTAG CATTTAAATA 9840 TACACAGTTT CTTATTCATC TGTCTTGTTC TTCTGCTAGT TTATAAATTG CTTGATTATA 9900 GAACATGAGC TTGATAATCT TTGATTTTTC CTGGATACTG TGTTCTTGCT AGGCTGTTAA 9960 TAATGCTTGT TGAATGAAAT GAGAAATGAA GAACGGCTGC TTTACCAGTT TGTCTCTTCT 10020 GCCAACTTTT TTACATGGAT TTTACACGTC AACTTTTTTA CACAATGATT AAATATACCT 10080 AATTTGATCA TCCCAACAAC ACTAGTAAAT ATATATGATC ATTATCCTCA TACTACAGAT 10140 GAGGAAACAC AGGCACACAT CGTTTGTTTG TTTTTTTTTT TGAGACGGAG TCTTGCTCTG 10200 TTGCCCAGGC TGGAGTACAG TAGCACGATC TTGGCTCACT GCAACCTCTG CTCCTGGGTT 10260 CAGGCCATTY TCCTGCYTCA GCCTCCCGAG TAGCTGGGAC TACAGGCATG TGCCACAATG 10320 CCTGGCTAAT TTTTGTACTT TCAGTAGAGA TGGGGTTTCA CTATGTTGGC CAGGCTGATC 10380 TCGAACTCCT GACCTGATGA TCTGCCTGCT TCGGACTCCC AAAGTGCTGG GATTACAAGC 10440 ATGAACCACT GTGCTGGGCC AAGCACACAT AGTTAAATAA CTTGCAAAAA AAAAAAAATC 10500 GTATCTATTT GTAGGAGGCA GAGTCGTGAT TCTGAGCTGA ATCTATTTGG CTCCTAAGCT 10560 TATGCTTTTT CTACAGTATC ACCACATATC CCATACTCTA TTGTTATTGT TGGCTTTATT 10620 GCCTGTTTTT CCTGTGAATT TTAACCTTCC CAAAAGCAGG AATCTTATCT CAGTATATCA 10680 CAGAGAATCA CTAAGTATCT ATAGAGGAAA GGAAGGAGAG AAGGAAAGAA GAAAAGGAAG 10740 AAGGAAAGGA GGGAAGAAAG GAAGAAGGAA AGGAGGGAAG AAAGGAAGGA AGGAAGGAGG 10800 GAAGGCAAGA GGGCAGGAAG ACAGAAAAGA AGGAAGGAAG AAGGAAGGAA GGGAGGGAGG 10860 AAGGAAAGAA GGGAGGGAGG GAGGAACGGA TAGGAGGGCA GAAACTCTGG AAAGGAGCTT 10920 GTCTTACTCC TAAGCTTGGT AAAGATCAGT CTTGCAAGGG GCTTGACTAG AAAACACTGG 10980 CTTATCTCAC TGAACCATAT TCCCAATGTC ATTGACTCCT TTCCCCTGGG GAGTAATTCA 11040 ACCATGTGTT CACTGTATGG ATCAGAGTTG ATGATGAATA TTCTCTTGCC TCAGTCTCTT 11100 TTGGCCAGAG TTCCTTGGCT TCCAGCCTGC TCCTTGCTTG TTTTGAACGA ATAATATATG 11160 ACTTTCCTTC TTAACTGGCA AATGCTGAAC TGTGGCCTCT CTTAACCCTC AAGTCTCCCG 11220 ATAAAAAGCA AAATATTAGA TTCGCTGACC AGCGCTACTC CTTACCCCGG CTGATTTCAC 11280 ATGAAGAGCT ATATATGGGG TGGTAACATA GGTTTAAGGA TGGATGTGCA TATAACTCCT 11340 GGATACCGTT CCTGAAAATA TACTATTGGG GATTATTTCT TTGGTTGAAG AGTCCCTTCA 11400 CTACCACATG TCAGTCCCCT TACCTATAAA ATGGGAACCT TAGGGTTGTT ATAAGGATTA 11460 AATGAGTTAA TGTGTATAAT GTGCTTAGCA CAGTACCTGC CACTCAATGC TATTATTGTT 11520 GTTGTTGTTA TTATTATTGG TAGTAGTAGT AGCAGTAGTT GTTGTATGAA GATGCATGAT 11580 TTCCTGGGAA AGGTAGCACA TTAAGGCAGG ATCAGTCATG AGTTACCTCA AGCAGATTAA 11640 TTTACTAGCC CTTTCATGCT ATTTCCCAAA GGGATGGTTT ATCAAGTTGA GGAAGATGTA 11700 GATGTGATTT ATGATGGATT TGAGGTTAGT ACTGTGTATC CAGGTTGTGT GTGAGAAGAC 11760 AAGAAGGAAC TGAGGGCACA GCTGTACTTA GGAAGAACTC TGGTTTGCAA GGTACATAAG 11820 CTAATTCAGA CGAGTTTAAA CCATAGGAGA TTTTGTTACA AAGGCACTAG GTAACTGCAG 11880 GGACCAGGGA GCAGGGTGTC CACTCTCATT CCAGATTCTT TTGAATTCTG TATATTTTAT 11940 TCTCTTTCCA CAAACAGACT TTCTATCCAC GGTGGTGATG ATAACCAATA ACATTTCCTT 12000 CAGTCTCACC CTTGTAGCTC TGTGACCAAA AATGCAAAGC TGCTGCTTCT CCAGCTTCAA 12060 AATTTAATAA GAATCACAGG GCAGAACATT TATTGGCTAG GCCTGAGTTG CATGTCTAAC 12120 CTTGGAGAAC TCACTTTGAA TAGGGGAATT CAGAACTAGG ATTGGTGGCT CCACAAATCT 12180 CACAAAAATG GAGCAAARTA GGAACTCATC AAACAGAAAT CAATAGATCT CCACTGGCTT 12240 TATAGTACGT GGTTCTGGGA ATCCAGATAT TCAGAGCCTA GGTGAACCTG AACATTTCCC 12300 TTTAGGCAGA TGGAAATCCA CGTTCTTCTA GCTAAAATTT TTCCATTCTC TTTGAGGGGA 12360 GTTTCCATGG AGAGGCTAGC TTTGTGGGAG AGAGTGGGAA RAAACAACTC ATGCTGTTTT 12420 TCATTGGGGA CCATTCTTAT TGCTACTTTA GTCCAGTCCT GCCCACGGAT CACACATTAT 12480 TCCTTACTCT TGTTGCTTCT GGGCTTTTTC TTTTTCCTTT GCATGCTGCT TATATTCCCT 12540 TCCCTAAAAG CTACTCTATT AAGAGGGAGA TTAGGCAAGT AGGCTGGTTT GATTATGTGC 12600 TGGTTTAACC CATAATCACA TACCTCAAAA AGAAAATGTC AGACACACTA TAATAGCTCC 12660 AGATACAAAA CATGAAGTAC GAAGACCTCT TCAGAAAACT GCAGGCTTGC TACTCACCCA 12720 CAGACAAATA GAGCTGATTC TATTAGAACA GTGAGGAAAG AACACAGTAA AGAATGGCAT 12780 TTAAGATCAA TTGTGGCAAT GTCTAATTTT GTCTGGGAAG ACCATGGCAG TGAGGGATGC 12840 AAAGGGATGA CATCAAGTTT TCAGAACAGT GCCTATATGT TTAGGACGAA GAGTTAAATA 12900 ATGAGAGAAA ACAAATGCAA TACAATTTCA TTGGCTACCT GGTTAGACCT AGCATGAACT 12960 GTGTCTGTGA TGGTGCTATT AATTTGTGAT GGAGACATTG GATATTGTCT TTCCCTATTT 13020 GGTAAGAGCT TGATTCAGGT AGAGAGAAAC AATAATTATT TTACAGTGTA CAAAGCACTT 13080 TCTTATACGA TATATTATTT TCATCCTCCC AACTAGTTTG ATAGGCAGTA ATATTATTCC 13140 CATTTCACAG AGGGGGAAAC CTGGGTTAGG GCCCAGGAAC TTGGCTGGTG AGTTTGGAAA 13200 GCTTGAATAG CAATGATTAT AATCTTGGTG CACAGAAGCA GCCAGTGAAA TTCTGAAATG 13260 CATATTTCTG TTCTCTACTT CCAGAGGGTC TGATTGAGTT AGCTTGGGGA AGGGCCTAAG 13320 AAATGGAATC TTTTTTATTC ACACCAGGTG ATTTTGAAGC ATGGGGTCTA CTGAGTATGC 13380 TTATGAAACA TTAACTTTAG GTCCTAGGCA CTGGCTTAGT TGACTGTGAG AAACTGAAGC 13440 ACAAAATTGT GTGACCAAGT TCTTTCTGAG CCTCAGTTTC CTCACCTGAA AAATGAATGA 13500 TGATGATAAA AATAACTAGG CTCCATGCCA AGTGATTTAC ATATTTCCCC TCAAATCATC 13560 TTTCTTACAA ACCTAGGAGT TCGGAGGCAT TGTTGTTCCT ATGCTATGGG ACTCAAACCC 13620 AAATCATTTC TACTCACTCT TCCTTTCATA ATTGTCAGGA AGATTAGACA TAGAAAGTAT 13680 CTAGCACATA TTCCTGATGT TGAAGGAATA GCAGCAGCTG TTATAACTAC TACTAAAACT 13740 GACAATACTG ACCATACAGC CACCACTAAA ATGYTGGGGT TGAATTCAGA TAATCTCTAA 13800 GGTTCTTCCC AGCTCCACCA TACCCTGATT TCAGCATTTC AAATATATGC TGTATTTGTG 13860 GGGGGGGTTC CTAGAAAGAG TGTGGCAGTA ACTGAACTCA ACTATACAAA AGACCGAATT 13920 CTTCCTTTAG TTGGAGATTT ATTGATTTTT GTAAGTGAGT TTATAGACAA AAACGAGGAA 13980 GATACAGAGA AAAAAGAGAA GAATTACTGT GCTTTGATAG TAGGGCTATG GGTGATTATT 14040 TTATTTTTAA AATTTTATTT TTTATACATT AATGTGGTTT CTATAACAAA CACAAATTTA 14100 GAATAAAAGT AAGATATTTC TCTTGTGCTT CCAATTTACC ATATACTTCT TAAATGTATT 14160 TGTATCATAA TCATCAGCTG TAAGTTTACT ATTAAAAAAA ATCAACAAAA GAACAATATC 14220 AGAGCTAAAG GACTTCAGGC CTGATGAACC TAAGTCTAGT TTCTGTGCTC ACTAGCCTTG 14280 GCTTATCCCA AAATATTAAA AGTAAAATAT GATCCAATCT GCATCTCTTG CACATGTCAT 14340 GTTTTGTAAA TAGAAAGTTC TTGGAACAAT CTGTAACATC GTTGAAGTAC TTCATTCAAT 14400 TCTTGGGCAT TAAATTTTAT CTTCTGTTCC TGCCTCATAT CATTAAACAG TACCTTCACC 14460 TACATTGCAG TCAACTATGG AGGACTAATG CTCTATTTTT TTTATGTTGA ACATGAAGCA 14520 TAAACATGTA CAGCTCTGAA CCTGAGTTTT CCTTGCTTTA GAAATAAGAG GTGTTGATGA 14580 AAGAGGAAAT CCCTGAGACT CTGTAAACCT WACCTGCAGG TATGAGAATA CAATCTGTGT 14640 TTWATTTATK GTATTCTTWA GCAAAATTAT AGTAAAATTA GTATTTTTCT TTTCATTTGC 14700 TCTCGAATTA TCCTTTAGTA ACAGAGTGAA CTTGTATGTC CATATTTTGG GTTTAAAGAA 14760 CATGGTTACT GTAGCAAAGA AGGGGCTAGC CCATGTATTA AGGTCCTGGA TTATACTGTT 14820 GCTCACAGGA GAGCATGGGT TTGAAGATGA GGCTGCATAG TAAAGTAGGT AAAAGTTTGG 14880 ACCTTGGGGC CAAACTGCCT AAGCTCAAAT CATGGTCCTG CCAGTACTCT CTGTTCGACC 14940 TTTAGCAAGT TACTTAATCC TTGTAGACCT CTGATTTGGT CTCTTCAAAA TAGGGATAGC 15000 AATAATGCCT GTCTTATAGA GACATTGTGA GGATTCAATG AATTGATATT TGTAGAAGAA 15060 TATTGAGTTG GTTTTGCTAG AAGATATTAA GTGCGCAGTC TTTCTAAAAT AACTAAATGC 15120 TACAAAAAGC AAAATAGCCA TTCTGCAAAG AGCAGTGATT GAAGCAGGAA AAATGCCTGC 15180 CTTCATAAAG CTTACATTAT AAGGAGAGAA AAATAAGCAA AACAAACTAC GTGGTATATA 15240 TGTAAAATAA AAATAAAGAG GGGGAAGCAT GGGGTGGGGC AGATATTGCA GTTATAAATA 15300 GAATGGTCAT TGGAGGCTTT ATTGAAAAGG GGACATTTGA GCAAAGTCTT CAAGGGGGTA 15360 TGGAAGTGAG CCATGTGAGT ATTTTGGTGT AGGGAAGGAA AAACATCCTT CTACCCTCTT 15420 AGGTTTGGTG GCTAACCTAA GAATTAAAAC AACATAGATT AACAAGAGAA AAGCATGCAC 15480 ATTTATTTAA TGTTTTTATG TATACATGGG AGTCCTCAGA GAAAAATGAA GACCCAAAGA 15540 AGACTTTATG CCCCAAAGCT TATATACATT TTTTACACAA AGAATGATAA ACTGTGGAGA 15600 TGTGACAAGA CAAAAGGCCT TGGGCTAGAA GCAGTAAATT GTGGGAGTAA GGGATATACA 15660 GGCGAAACTA GTGGAAAATG AGGATGATTT TAGTTTTTTT TTACAGGTCC ATTTCGATGA 15720 TAACTCCAGT CATCTCTGGT GATACTATTC TTCTCTTCCT GGCACAAGGA GGGCACCTTT 15780 CTCATGGGAA ATTTTATGAC CTGCTTTTTG GTAGAAAGGG GAAGTCTGAG AGCTCTTCCT 15840 GCCCCTAGTG TTTCTCAAGC GCCTTCAGCT CAAAATAATC ATTATGCCAA AGTGGCATAT 15900 TTTGAGGTGG CATGTTCTGA GCCATTTCAT GGGGTAAGGA TATTCCAGGC TGAAGGAACT 15960 GGGAATGCAA AGGCCCTTAG ACAGGAACAT GCCTGGTATA TTCAAGAGAC ATCTGGGAAG 16020 CCAAGGTAAT GAATGACAGC AGAGCATGAG GGTGTGGGTG GCAGGAGATG AGGAGATGGT 16080 ACAGGAGGCA CAAATCAGGC AGCATGTTAT TGATCACCGG CAGAGCTCCA GGTTTCATTC 16140 CATTCTGAGT GACATGAACG GCCATCAAAG GTGTTTGAGT AGAGGAGTGA CTGTGTTTAG 16200 AATGGACTGC AGGGGAATAA GGGTAGAAGC GGGAAGACCA GTTAGAAACT GTTAGAGATG 16260 ATAGTGGCTT AGACCTGAGT GACAGCAGTA GAATAGGTAA GAGATGGATT ATGAGTGTGT 16320 CTGGCTGATT CACTCTTATA TCCCCTATGC TAAGGCATCA TGCTTGGCAC ATAGTAGGGA 16380 CTCAATAAAT ACTTGCAGAG CGAATGAATA AATGGGAGTT CAACTTGGGT AAGGCAACTT 16440 CTCTAAGGCT CTGTTTCCTC ATCTCTAAAA TGAGGGTAAG AAAAATATTA ATAGATCTAC 16500 CTCCAACGGT TATTGTGGAG ATTAAATGAG GTCATTCCCA TGCATTGCTT AGCATAGTAA 16560 CTGAAACATA AGATAGGGCT AAGATGTATA CATACACATA AATATAAAGC ATTTTTGCAA 16620 GAGTTTACCT TTGGAGACAT GGAGGAAGGT AGACTTTTAT TCTTCATTTT ATGAACTAAA 16680 AGCAAAAGAA GAAAACAAGT GTTGAAATTA TGAGTCATTT TCAAGTTCTT TTTGTACTTT 16740 TCACTACCAT TTGGAATTTT CCTATAATGA ATATGCGAGG CAAAGACAGA AATGAAAGGA 16800 TAAGATCACT CAGAATTTCA GGTTTTTATA AAGCATCAGA AATGTAAGAC TTTTTTCTGC 16860 TACTGCATGG CCCATTTCTC TGACTCTTTG AATGTGGGTA TTATTCTCAT CTTTCTCCCT 16920 CCTCTTCTCT TTTTGGTTAA AAGTAAAGAG AGCTTTTGAA GCTATTATGG AACAAGAACA 16980 ACAGCCTAGT TCATCCTCAC ATTTTGGAGC CTCTTATTCC TTCCAAAGAA CAAACACATC 17040 TATTTAGTGG CTAAGAGTCT CTTGAGCTGA AACCATTCAT CACCATAACT ACATTCAAAC 17100 TGTCTGAGGT ATACATTATA ACTAAGAAAA TGGGGTTCCT CATTGGAATT TACAAACTAA 17160 ATATTCAAAG AAGGGTTCTG ATGCTTTTAA AATAGGGGCG CCACCAAAAG GTAAAGTAAG 17220 ACATGTGGTT GAAGACACAG GAAAGGGCAG AGGTCACCAG AAAAGTTGGT TGTCACGCCT 17280 GATCTTAGGG CCTCATAAAG AAATAATTAT GGCAGAATGA GCCCTAAGAA GCAAGCACTT 17340 TAGCATGGCT CTCCCTGGAC AAAGTGGAGA GGCCCTTCCA CCCTAACTTA TCCTATTGTC 17400 CTGGTCTTCA GTCTTTCCTG TCTGTTTGCC TTTCCTGGTG TTAATATACT TGTTCCTAAG 17460 GTTTTCACCC TGCTGACTTT TAGCTCTTCT TGCTAAGATT CCTGGCTGTA CATTAGAAAA 17520 CTCCTGAGCA ACTAAACACA AAAAAATATT TGGCAGGGGG ATAGGGGGTG CTTCTAGGCC 17580 CTAACTAAGA CCTGTTAAAT TAGAGTCTCT TTCGGGTGGC TCCTGGGCAT TGGGGTTTTT 17640 TTGTCCTTTT TTTTTTTTTT TTTAAATCTA AAGCTTCCCA GTTGATTCCA ATATGTAGCC 17700 AGAATTGAGA CCAGAAAGCT GTTAATACCC AAGTAGTATA CTAATATTAA TAATGATCAT 17760 AATAGATTAA TAACTAACAT TGAATGAACT TTAAATGTGT TAGCTGATTT AATTCTCAAT 17820 GACTCTGAGG CAGTTACTAT TATTATTAAT GTACCCCTTC TACAGATGAA GAATTCAAGA 17880 TACCAAAAAT CTACATAATT TGGCAAACAA GTAAATGCTA AAGTTGGAAT TCAAACACAG 17940 GTAGTTTAGT GTCCGAGCCC ACACTCTTCA CCACCACACT GGTGGATTGC CCACCTGCAA 18000 TGTTAAAAAT CGCAGAGGAT AGTGATGATA CTGCAGACAC ACTGCCTGCA TTTTATCTCC 18060 TCCTTGTTAG GCTGAGCCAT TCATACCTCA GTGGTCCACA CCTTAAAGGC AGGATATAAA 18120 GGTAAATATA TGTACCTTCT CTGATATGAA CTAGAGACTC CATCCCTTCT TTTTAAGTAA 18180 TGTAAATGAT TAACCAGCTT TCTGTTATTC CTTTCAGAAT CTCATTCATA GAATAAATTC 18240 CTGGCATAAA TTAGTATCAT AAGTTTTCTA TTATTGCTCA TTAATCAGTA TGTGATGTAA 18300 GATCAAGCAG TAAGAGTTCC CCCCAACCCC AAAGAATGGT CTTTCTGTTT GTGACAAATT 18360 ATTCTTGGCA ATGTAATTAG CCAGTTGGGT TATTGAGGGG GATCCACTAG TTCTAGAGCG 18420 GCCGCCACCG CGGTGGACTA GAT 18443 (2) INFORMATION FOR SEQ ID NO:7: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 11811 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:7: CCTGTTAAAG TTTACCTTGT ATCTTAAAAC TTGCCCTAAC CGGATTAATT TTCTGGCCAA 60 ATAGGGAGGC TGAATGAAAG TTTCACATAA ACCTTAGATA CTCCTAATTA ACTGTTTTTT 120 ATGTCTGTTT TTCTAGGACA CATGTTCAAA GAGCATAATT AACTTTTTAA AAGAAGCTAG 180 TAAGTACTGA AATAGTTTTT TAAGTTTTTT CTACAAGAAT AGAGGAAGAA AGGAAACATG 240 GAATTCTGAA GGGCTACTTA GCAAGCTGCT TATGGCATAA TCTGGGGTGG GGGTGCATAG 300 TAAAGGATTT GCATTTTACT GAGACCGATA CATGTCAAGG GAATGGTATT TAAAATTAGT 360 GATATGTGTT GATTTTTCAA GGACTATAGC CCATCAACTA CAATAGGCTC CAAAAAATTC 420 TGGTGAAATT AGCTTCTTGG AGCCTTCCAG TTTACCTACT ATGTTATTCC CACTATAAAA 480 TATTCTCAAC TTTTGGGGTT TTAGCCACTT AAGTTTTTTA TTTTCTCTAA TGTCTCTAGT 540 ATCTGCTTTA GTTTCCTGTC AATGCTAGAC TCTGTGGTTC AGCAGTTCAT CCATTCTCTT 600 CCCAGTACTC AACCTCGTTG CTTATAGTTT CATTACATTC ATCTAGCAAA ACCTTAATTC 660 TGTATGTTTG CCATACCATT AGTGCTTAGA GCATTTTTTC AGAAAAGAAT CCTGGAAAAA 720 TGGATCTTAT CTCACCTGGG CCCTCAGGAC TGCTGGGCTG CCTGGTGTCA GCACTTCCCG 780 CCATTTTCTA TAGCACCAGT ATTATTCTTA ATACTTTAAA AAACCACCAG GCACGGTGGC 840 TCACGCCTGG AATCCCAGCA CTTTGGGAGG CCAAGGTGGG CGGATCACAA GGTCAGGAGA 900 TCAAGACCAT CCTGGCTAAC ACGGTGAAAC CCTGTCTGTA CTAAAAATAG AAAAAAATTA 960 GCTGGGCGTG GTGGCATGCA CCTGTAGTCC CAGCTGCTGG GGAGGCTGAG GCAGGAGAAT 1020 GGCGTGAACC CGGGAGGCGG AGCTTGCAGT GAGCCGAGAT TGCACCACTG CACTCCAGCC 1080 TGGGTGACAG AGCGAGACTC CGTCTCAAAA AAAAAAAGTA AATAAAAATA AAAAACCATA 1140 TCCCACTATC TCCCCCTTCT CTCTTTGCCT GTGATCTTGC TGCATACTTA TGGGGAAATC 1200 TTTAAGATGT CAGATTTCAG TTCTCTCACT TTTCTACAAC TTCTCCCACT TTTGCCTTTC 1260 TTATGTACCT TCCCTTCCTT CCCATCTGAT TCCTTATCAG TATTTACACA TGATTAGTTC 1320 TTGCCTAACC TAATAGACCC TTTCTTGAGT GCAAATCAGT GGCTATTTTT GCTAGGGTAT 1380 AAAAATTACC TATCTAATCA CCTTGACAAA GTTACCCTGT TATTTCCAAT AACTTACTTC 1440 CTATGGATTC TTGTAGATTT TCTTTTTTTT TTTTTTAATT TTTTTATTTT CAGATGTTTT 1500 CTCGCTTTGT CACCATGCCT GGCCTAAATT CTCGTAGGTT TTCTATGTAA ACAATCAGAT 1560 TTTCTGCAAG TATTAGTCTC CTTTCTAATT GTTATAATTT TAATTTCTTT TTCTTTTTAA 1620 AATTTTTCGT AGAGACAAGG TTTTGCTATG TTGTCCAGCC TGGTCTTGAA CTCCTGGGCT 1680 CAAGCAATCC TCCCATCTCA GCCTCCCAAA GTGCCATTAC AGTGGCATGA GCCACTGTGC 1740 CTGGCCAAAT TTCTTTTCTT GTTGCGAAGG CAGACTTTTC ATACAATACT GAATAGAAGT 1800 GATAGTAGAT TACTTTATTT CTGATTTTCA AAGGAATGCT TTCCGTTTCT CTCTGTTGAA 1860 GATAATTGCG TATTGTTTTT TTTTTTAAAT AGTAACTTTT ATCAGGTTAA GGAAGGTTTC 1920 TTCTATTTCT ATTTAAAAGG ATTTTTTAAA ATCTTGAATT CATATGTTTT TATCTAATGC 1980 ATTTTCTACA TCAGTTGAAA TGGTTGTATG AACTCTTTTA ATATGGGTGA ATTATATTTA 2040 TAGATTTTAT GTTAAAATAT CCTTGTATAT CTTGGATAAA CTCAACTGGA TCATGATTTA 2100 TCTTTTTTAT ATGCTAGATT CAATTTGTTG ATACTTTGTT ATGATTTTTG AATATATATT 2160 ATTGTGTAAA AGTGAGCCTG TGATTTTCTT TCTTGTAATG TTTCTGTCCA GTTTTGGTGC 2220 CTGGTTTTGC TCTCTCCTTA GAATGAGCTG GGAACTAGTC ACTCTTGTTT TCTCACCTAT 2280 AATAGCATCT GGGTCCAGTG TTTTTTATGT GGGACAAATT TGAACTTGTG GTCAACCTCT 2340 TTAATTGTAA GAATATTCAG GTCTTTTGTT CTTCCTGGGC TAGTTTTTTA TTCTTTTTCT 2400 AGAGATTCGT TCATTTTTCT TAGTTTTATT TGCCTATAAT TGTGGATAAT CTGTTTTTTA 2460 TCTGCTACTT CTGTAATTAT TTCCACATTT GATTTATAAT ATTAACTTGT GGGCCAGGCG 2520 TCGTGGCTCA CACCTGTAAT CCCAGCACTT TGGGAGGCCG AGGCGGGCGG ATCACGAGGT 2580 CAAGAGATCG AGACCATCCT GGCCCATGGT GAAACCCCGT CTCTACTAAA AATACAAAGA 2640 AAAAAATTAG CCGGGCGTGG TGGCAGGCAC CTGTAGTCCC AGCTACTCAG AAGGCTGAGG 2700 CAGGAGAATG GCGTGAACCC AGGAGGCGGA GGTTGCAGTG AGCCGAGATC GCACCACTGC 2760 ACTCCAGCCT GGGCGACAGA GCGAGACTCC ATCTCAAAAA AAAAAAAAT TTACTTGTGT 2820 CTTCTCTTTT TACCTGTTTG TTAATTTATC AAATAACTAC TTTTGGCTTT GTTTCATTTT 2880 TATTATACAA TAAAATGAAA TTCTTTTCAT TGTATTTCTT TTCATTGATT ATTCCTATAA 2940 TTCTTAAACA ACTTTATAAT TGATGTAACA ATAACCTGTA CACATTTAAA GTGTAAAATT 3000 TATTACATTT TGATCCATGT ATATAGCAGG GAAATATCAC CACAACAAGA GTGTGAACAT 3060 ATAATCTCTC CCCAAAGTTT TCTTGTGTCT TTTATAATCA CTGCCTCTTG CCCCTGCCCA 3120 CTCCCTCATC CTTAAGCAAC CATTGGTCTG TTTTCTGCCA CTATAGATTA GATTGTATTT 3180 TCTAGAGTTT TATACAAGTG AAATCATGTA GTATAGTATT AACCATGTGT TTGTTTGTTT 3240 GTTTGTTTCT TTCTTTCTTT CTTTTTTTTT TAGACGGAGT CTCGCTTTGT CACCCAGGCT 3300 AAAGTGCAGT GGGGCGATCT CGGCTTACTG CCAGCTCCGA CTCCGGGGTT CACACCATTC 3360 TCCTACCTCT GCCTCCCGAG TAGCTGGGAC TCCAGGCGTG CCCGCCACCA CGCCCAGCTA 3420 GTTTTTGTAT TTTTAGTAGA GACGGGGTTT CACCATGTTA GCCAGGATGG TCTCGATCTC 3480 CTGACCTCGT GATCCGCCCA CCTCAGCCTC CCAAAGCGCT GGGATTACAG GCAGGAGCCA 3540 CTGCGCCCAG CAACTATGTG TTTCTGATCC TTTGTCAGGG CTAGCCAATT CCTAGAGACA 3600 GTGAATAACT CACTCATAAT CTAGCTGCCT CCTTTATGTC GCTCTCATAG GACTTTGACA 3660 CCTCTCTGCT ACAATCCACC TGCCCTGTTC ATTTCAAGAT CAGGTACCAG GAAACTCGGG 3720 ACATCCCTAT GCTGCAGAAC TCACTGAAAT TATTCAAACT AGCCAGTCCT AAACATGCTT 3780 ACCCTGCCTT GCCCATTCCT TCCGCTGAAA CCACATAAAG GCTCTTGCCC ATGTTTTCAT 3840 CCCATTCCAT TGACCTCCTT ACTGACCCTA GCTAGTGCTT CCTCATGTGG CCCCTGCATG 3900 GCATGGTGTG CACCTTCCTC TTCGGAACTG CGAGTAACTG TCTTGTCAGC GGCAATCATC 3960 TTGTGATCTG TTGGCCTCAT CATATTTGAA TAACAATAAA ATCTGTTTTA AGGCTGGGCG 4020 CGGTGGCTCA TGCCTGTAAT CCCAGCACTT TGGGAGGCCA AGGCAGGCGG ATCACGAGGT 4080 CAAGAGATTG AGGTGAAACC CCCTCTCTAC TAAAAGTAGA AAAATTAGCT GGGCATGGTG 4140 GTGCGTGCCT GTAATCCCAG CTACTCAGGA GACTGAGGCA GGGAATCTCT TGAACCCAGG 4200 AGGCAGAGGT TGCGGTGAGC CAAGATTGCA CCACGGCACT CCAGCCTGGT GACAGAGCGA 4260 GACTCCATCT CAAAAAAAGA AAAAAAAAAA ACTGTCAAAT GATACTCCAA AATGGTTGTA 4320 CCATTTTATA TTTGCAACAA CAATGTCTGA GGGTACTGAT TGCTCCATAT CCTTGACAGC 4380 ACTTGGTATA GCTGATCTTT TAATTTTAGT CACTTTAGTG GGCATATACT GGTATTTTAT 4440 GTTTTACTTT TTATTTTCCT AATGATTAAT AGTTTGCAGC ATCTTTCATG TGCTTATTTC 4500 CCTTTCATAT ATCTTCTTTG ATAAAAATAT CTGTTCAAAT ATTTTGCCCA TTATTTTGTT 4560 GGAATACTTA TTTTCTTACT GTTGAGCTTT GAGAGTTCTT TATATATCTG GATACCAATC 4620 CTTTGTCAGA TATATTTTTT GCAAAATTTT TTCCCAGCCT GTGATTTAGT TTGTTATTCT 4680 CATGTCTTTT AAAAAAAATT GTAGTTAAAA TATACACATA ATACAAAATT TAACATTTTA 4740 ACTCTTTGTA AGTATACAGT TTTGTGGTAT TAAGCATAGT CACATTGTTG TGCAACCATC 4800 ACCGCCATCC ATCTCTGGAA CTTTTTCATC CTCCCTGACT GAAATTCTGT ACCCATTTAA 4860 ACACTAACTT CTCATTCCCC CTTACTCCAG CCCCTGGCAA CCATCGTTCT GTTTTCCTTC 4920 TCTATGAGTT TGACTGCTCT AAGTACTTCA TATAAGTGGA GTCATACAAT ATTTTCATTT 4980 TGTGACTGGC TTATTAGTAT AATGTCTTCA AGTTTCATCC ATGTGGTAGC ATGTGTCAGA 5040 ATTTCCTTCC TTTTTAAGGC TAACATTCCA TCCTATGTAT ATACCACATT TTATCCATTC 5100 ATCTGTTGAT GGACATTTAA GTTGCTTCCT CCTTTTGGCT ATTGTGAATA ATGCTGCTGT 5160 GAATGTTGTT GTATAAATAT CTGTTCGAGT TCCTGCTTTC AATTCTTTTG AGTATGTTCC 5220 CAAAAGTAGA ATTGCTGGGT CATATGTTAA TACTGTATTT AGTTTTTTGA GGAATTGCCA 5280 TACTGATTTC TATAGTAGTG GTACCATTTA CATTCCAACC AGCAGTGTTC AGGGTTCCAA 5340 TTTGTTAACA TTCTTGCCAA CCCTTGTTGT TTTCTGGATT TTTTTTATTT TGGGGTTTTT 5400 TATTTTATTT ATTTATTTTT TTTTTGAGGC AGAGTCTCAC TCTGTCACCC AGGCTGAAGT 5460 GTAGTGGCGC AATCTCGGCT CACTGCAACC TCTGCCCCCC GGGTTCAAGC GATTCTCCTG 5520 CCTCAGCCTC CGAGTAGCTG GGACTACAGG CGCGCGTTAC CACGCCTGGC TAATTTTTTG 5580 TATTTTTAGT AGAGGTGGGG TTTCACTGTG TTAATCAGGA TGGTCTCGAT CTCCGGACCT 5640 TGTGATTCAC CCGCCTCAGC CTCCCGAAGT GCTGGGATTA CAGGCGTGAG CACTATGCCT 5700 GGCCATTTTT TATTTTTAAA CAATAGCCAT CCTAATGGGT ATGAAATAGG TTTTTTGGTG 5760 TTTTGTTTTT TTTTTTTGAG ACAGAATCTT GCTGTGTTGC CCTGGCTGGA GTTTAGTGAC 5820 GTGATCTCGG CTCACCTCAA CCTCCGTCTC CTGGGTTCAA GCACTTCTCC TGCCTCAGAC 5880 TTCCAAGTGG CTGGGACTAC AGGCGCCCGC CACCACACCC AGCTAGTTTT TGTATTTTTA 5940 GTAGAGATGG GGTTTCACTG TGTTGGCCAG GCTGGTCCAC GATCCATCCA CCTTGGCCTC 6000 CCAAAGTGTT GGGATTACAG GGGTGAGCCA CCATGCACAG CCAGGGTTTT GTTTTGTTTT 6060 GTTTTTACTA TTTTTTTTTT TTTTTAGAGA CAAGCTGTCT CCCAAGCTGT AGTGCAGTGG 6120 CACCATTCGT ATCTCACTGT AACCTCAAAA TCCTGGACCC AAGCAATCCT CCTGCCTCAG 6180 CCTTCCATGT AGCTACCTCT ACAGGGAATT GCCCCCATAC CCCGGGAAAT TTTTTTTTTT 6240 TTTTTTTTTT GAGAGTTTTG CTCTTGTTGC CCAGGCTGGA GTGCAATGGC ATGATCTTGG 6300 CTCACTGCAA CCTCCTCTTC CTGGGTTCAA GTGATTTTCC TGCCTCAGCC TCCTGAGTAG 6360 CTGGGATTAC AGGCGCCCGC CACCACGCCT GGCTAATTTT TTGTATTTTT AGTAGAGATG 6420 GGGTTTCACC ATGTTGGCCA GGCTGGGCTC GAACTCCTGA CCTCAGGTGA TCCACCCACC 6480 TTGACCTCCC AAAGGGCTGG GATTACAGGC GTGCGCCACC ACACCTGGCC CCCAGCTAAC 6540 TTTTAAATGT ATTTTGTAGA GATGAGGTCT CACTGTGTTG GCCAGGCTGG TCTTGAACTT 6600 CTGAGCTCAA GTCATTCTCC CACCTCGGCC TCCCAAAGTG CTGGGATTAC AGGCATGAGC 6660 CACCACACCT GGCCCCTTTG CCCATTTTAA AAATTAGGTT GTTTTTGTTG TTGTTGAGTT 6720 GTAGGAGCTC TTTGTATATT CTGCATTTCG GTTCCTTATT GGATATGTGA TTGGCATACA 6780 TTTTTTCCCA TCCATGGATT GCTTTTTCAT TCTGTTATAG TATCCTTGAT TCACAGAAGT 6840 TTTTAATATT GATGAGGTCC TGCTTAGTCT GTGTTTTGTT TTGTTGCTTG TGCTTTTGGT 6900 GTTATATCCA AGAAATTTTT GCCAAATCCA AAGTCATGAA GCTTTGCCCT CTGTTTCCTT 6960 CTGAGTTTTA TAGTTTTAGG ACTTAAATTT AGGTTTTCGA CCCATTTTTA GTTAATTTTT 7020 GCAAGTGGTA TAAGGGAGGG GTCCAGCGTT ATTGTTTCAC GTGTAGATAT ACAGTTTTCT 7080 GAGTACCATT TGATGAAAAG GCTGTCCATT GAATTGCTTT TGCAACTTTT ATTTGGGCAT 7140 ATTTATGTGA GTCTGTTACT GGTTCTATAT TTTACTCCAT TGATCTATGT GTCTATTCCT 7200 CTGCTAATAC TGTCTTAAAT ATGGTAGCTA TATAGTAAGC CTTAACACTG AGTAGATAGA 7260 TTTCTCCCCT TTTTTTGTTC TTTTTCAAAA TTGTCACTGG TTTGTTTTTA TTTTTTACTT 7320 TATGCAGATA ATCTGTACTA TACTTTGGTT TCATGTATCA AGTAGTTTGT TCCAAGTTGT 7380 GCTTTAAGCA GAACAAATAA ATTTTCATAT TGTTCTTTGT GTTAATCTGC AATATAAACC 7440 TATACCAAAT TCTATTTTGT GTATTTGTTT ATTGTAGTAA TCTGACTGAC TCTTTTGCCT 7500 CCAGACTCAT CTCTTTCAAG GTCCCCAACT GAATCTTGTT TTAGGTGGAA CTTAGAAGCA 7560 GTAGAAGTTA AGAATCTATT TCACAGCCTT AGTAGTCTAG TTTCATTCTC TATATAATGT 7620 TGTCTATGCA AGTGAGCTGC TCTCCAGTGC CTTAGTTTCA CTAATGTTGG GGAAGGTCTC 7680 TTCTCTTGTT TTGGACTTCT CTATCACATT GCCTTTCTCA AGAGAAGACA TATAATGAAA 7740 GTTGATATCT GGTGTTCTAG GACTTCTTCA GAAGCTTGCC AGTTTTTCAA GCTGATTTCT 7800 CTCACTGGCA ACTCTTCAGA GTGCTGTTCC TACTCCACCC TCCCCTGGTG GTATGTATCA 7860 GTTTTCTACT CATCAGCACC CACCTACTCC TGCCTACTGT GTTTCTCAGA TGTCTGCTGC 7920 CTGGCTAGCT CATTGCTGCT TTTGTCACTC ATAGAGCTGT CTTCTTCCCT TTTTTTGGCT 7980 TTCTGCCTGA CTTCCAGGGC AGCTGCTCTG TCATTGCCTG TCTGCCATTC TGTCTTTTTT 8040 CCCCCTACCC CCCACAGATA CAACATCTAC TCTAATACCA CACATTCTCC ATGTTCAAAC 8100 TAACCTCATC ACTTTCCCCA CCACATTCCC CAAAACTGGT CATCCTCCAG CTTATAGCAT 8160 TGCAGTTCAC TGAAGTTAGA CATCTGGGCC TTGCTTACCT CCAACATCTC ATTAGCCTTC 8220 GATTCTACCC CTATAAATCC TCTTCTCAGT CTCCTTTAGA TATTCCTGCC CTGCTGTGAG 8280 ATCCATCTGG TTTATTGGCT AGATTACTTC AGAAAGCTTC AGTCAGTGAC CCTCCTTACT 8340 TCAAACCCCA CCAGTTGATC CTTCACTCTG CCATCAGTCA TTGCTTCTAA AATCTAAATT 8400 GTTCCATTTA ACCTTGCTGT GATAAAACCT TTGGTAGTTC TTCAGTGTGT TCAGTGGTAA 8460 GTTAAAACTT TCACTGTAAT GTACAGGCCC CTTCATGATA TGATCGCTGC CTCCTCGAGC 8520 CTCATTGTGT GCATTTCCCC GCCCCACCCT TTCCTCACCC ACCCTAGTCT TTCATGTCTG 8580 CCATTTTTAC ATTCATTTAG CAGATATTTA TTGAAGCCCC CTGTGATGTC CTTACCTAGG 8640 TCTTTCTTGT TGCCAGGACC AGACAGGCTT TTTCAAGCTT CCAAGTCATC TCAGTTTGAA 8700 AGACTATGTC TGACCCTTGT CTTGGCCAAT TACTCTTTAT CCTTCCAAGT TCAATGATTG 8760 TCCCACTGCA CTCCAACCAG AGTGAGAGAG CAAGACCCTG TCTCAGTAAA TAAAAATAAA 8820 TAAATAAATA AATAAATAAA TAAATAAATC AGCCATAATT TATTTAATCA TGTCTCTCTC 8880 CCCCATTGAT AGACGTTAAG GGTATTTCCA GTATTCTTCT CTTGAAAACA ATGCTACATT 8940 GAATAACCTT GTACATGGGT CACTTTGAAA GTATGGATAT GTATCCGTGG AATAAGTTTC 9000 CAGAAGTGGA ATTGTGTCAG AGGGGTTGTG CATTTGTAAT TCTGATGAAT ATTTATAGAT 9060 TATATGAGAG TACCTGTTTA CTCAAACTCT TGCCAATGCA GCATTATCAA AGTTTTTTAT 9120 GTTCGCCAGT GTGATAGATT AAAAAATGGT ATCTCAGCCA GGCGCAGTGG CTCACGCCTG 9180 TAATCCCAGC ACTTTGGGAG GCTGAGGCGG GCAGATCACG GGGTCAGGAG ATCGAGACCA 9240 TCCTGGCCAA CACAGTGAAA CCCTGTCTCT ACTAAAAATA CAAAAAATTA TCCAGGCGTG 9300 GTGGCGGGCA CCTGTAGTCC CAGCTACTCG GAAGGCTGAG GCAGGAGAAT GGCATGAACC 9360 TGGGAGGCGG AGCTTGCACT GAGCCGAGAT CGCGCCACAA CATTCGAGCC TGGGCGACAG 9420 AGCGAGACTC CGTCTCAAAT AATAAAAAAA AAAGATGGTA TCTCAGCATT GATTTCTTTG 9480 ATCATCAGTG AGGTTGAGCA TCTTTTCATA GATTTAAGAG AACTGTATGG TTTTTTGTGA 9540 GTTATGTTTC ATATCGTTTA CCCATTTTAC TTTTAGGCTG GAAGCAGCTG TTTTAGTGGA 9600 ATGGTGGAAC AAGAAGCCAG ATTGCCATGG AGAGACAACT CTTTCTAGAG ATTTGGCTAT 9660 GAAGCAGAGT AGAGACAATG ATAGCTGAAG GATTGATGTA GATGCAAAGA AATTTTTCAT 9720 CTTCTTTGAA AACTTAATTG TGTTAAAAAC TGGTATGAAA GGGAGGGGTT AAAGCTAGAG 9780 ATGGTGGTAG AAAAAAATGC AGGGTTCCTA AAGGACTGAG ATTCCTGGAT GGAATTTCAG 9840 GGAAGGGGAA AATTTCTGGA TATAGTGACT GGGGAGTTAA GGGTGTCTAG TCCAATGGCT 9900 TTTATTTTCT TGGAAGGGTA GGCAAGGCCA ACAGCCACAT GTGTGGGAGG AGATGGTTAG 9960 AGGGGAGAGG AGGTTTGAAG GCACCGCTAT GGAGAATTGG AGAGAGCTAA GGAAAGACAG 10020 AAAGACTGCA GAAAGTGCTT AGGGTTCCAC TGAAGCGGAA ATAGTGATTT GTAGTGATAC 10080 AACCCTTATG AGTTATTTGA TTTTTTTTTT TTTTTAAGCA GCATCTGGCA GTCCAAGTAT 10140 AGGGCTGACA GTTTGGGATT TTTCTTTCCA TGTTGGTGTA AAAGAAGAAC AGTGTAGTGA 10200 AGGAAGTTAG GACAAAAGAA TGATTGAACT GACACCAAGT TTTCTTGATT TGGTAGAAAA 10260 GGAAATAAAG ATAGAGCAGA GATATTGAAA AGAATTAGAG AGGGGTTCAA GAGACTGAAG 10320 GCCTGGGTGA GGTCAGAGAG CAGGTGTGGT AGACATAACA GAGAGAACTA CAAGGATAGA 10380 AAGTGTGGTT GGAGAGTGGG AAGGCAAGAT TTATTCAGTA TGGGGGCTTT TCTGGGTGAT 10440 GACAGCATCT GGAGTACAGC CATTGTCGTG AGTGGCCCAA GTGTAGCAGA GATAAAGCGT 10500 TGTTGGAGTG AAGGAAGTCA AGGAACTGAG AGGCTGGCCT AGATGGGGAT TTTGGTTGTC 10560 ATCCATGAGG ATATTGAAGT CATCCAGGAG AATAGCAGGC CTGGGGGACA GGAAGGAAAC 10620 TGAGCCACTT ACAGTGTCTT CAGTGATAGG AAAGCACAGG GCAAAAAGCT TTCAAGAACA 10680 GGGACTGTTA AGCCGGGTAC AGTGGCTCAC ACCTATAATC CTAGCATTTT GGGAGGCCAA 10740 GGCGGGTGGA TCACTTGAGG TCAGGAGTTC AAGACCAGCC TGGCCAACAT GGTGAAACCC 10800 CATCTCTACT AAAAATACAA AAATTAGCCA GGCATGGTGG CACGCGCCTG TAATCCCAGC 10860 TACTTGGGAG GCTGAGGCAG GAGAATTGCT TGAACCTAGG AGGCGGAGGT GGCAGTGAGC 10920 CTAGATCGCG CCCTTGGCTG CGATCCAGAC TTCACTCCAG CCTGGGTGAC AGAGCAAGAC 10980 TCTGTCTCAA AAAAAAAAAA GAAAATCAGA CTCTTAATAT TTGTAAAGAA GTAGTCCTTG 11040 AGCTACTACT TAAGTCTAGA AAGAGTTGAT ATTCTTGTTT TAAGAGTGTT AGGGCACTTT 11100 GGGAGGCTGA GGCAGGTGGA TCACTTGAGC CCAGGAGTTC CAGACCAGCC TGAGCAATAT 11160 GGGGAAACCT TGTCTCTACT AAAAATACAA AAATTAACCA GGCATGTGGT ACGTACCTGT 11220 AGTCCCAGCC ACTTGGGACG CTGAGGTGGG AGGATCACCT GAGCCCAGGA AATGGAGGTT 11280 GCAGTGAGCC AAGATTGCGT GACTGTACTC TAGCCTGGGC AACAGAGCAA GACTCTGTCT 11340 CAAAAAAAAA AAGGGCGGGG ATTATCATAG TGCCATTATT ATTATGAGTT TATGATGGCT 11400 TTCTCTAAGC ACCTTTTACA TTCGGCATTT ATTCAGTACC TATTAAGCAT CAAGGAGTCC 11460 AGAAAAAATT TTATATATAA ATATATATAA AATATGTAAA TATATATATG CATATGCTTC 11520 CCTATCTCAG GAAGGAAATA TGTGAACATC AGGAACCGAA GTCTACTCAG TTACATGCCA 11580 TTGGATATAT CACACAAAGT GCTGAGGGAA CTCAGAAGGC TCATTATATC TGGGGAGTGG 11640 GAAGGAGGCA CAGAGATGTG CTTTGGGAAG TTTAAATTAA AATAGCAAAT GGGGAAAATG 11700 AAGACACACC AGACAGGGCA CAAGCAAAGA GACATGAAAG AGTAAGTCAT GTGTTTGAGG 11760 ATCTGGGGAT CCACTAGTTC TAGAGCGGCC GCCACCGCGT AGCAGTTACG G 11811 (2) INFORMATION FOR SEQ ID NO:8: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1241 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:8: TCGTGATGCG GTATTTTCTC CTTACGCATC TGTGCGGTAT TTCACACCGC ATAGATCCGT 60 CGAGTTCAAG AGAAAAAAAA AGAAAAAGCA AAAAGAAAAA AGGAAAGCGC GCCTCGTTCA 120 GAATGACACG TATAGAATGA TGCATTACCT TGTCATCTTC AGTATCATAC TGTTCGTATA 180 CATACTTACT GACATTCATA GGTATACATA TATACACATG TATATATATC GTATGCTGCA 240 GCTTTAAATA ATCGGTGTCA CTACATAAGA ACACCTTTGG TGGAGGGAAC ATCGTTGGTA 300 CCATTGGGCG AGGTGGCTTC TCTTATGGCA ACCGCAAGAG CCTTGAACGC ACTCTCACTA 360 CGGTGATGAT CATTCTTGCC TCGCAGACAA TCAACGTGGA GGGTAATTCT GCTAGCCTCT 420 GCAAAGCTTT CAAGAAAATG CGGGATCATC TCGCAAGAGA GATCTCCTAC TTTCTCCCTT 480 TGCAAACCAA GTTCGACAAC TGCGTACGGC CTGTTCGAAA GATCTACCAC CGCTCTGGAA 540 AGTGCCTCAT CCAAAGGCGC AAATCCTGAT CCAAACCTTT TTACTCCACG CACGGCCCCT 600 AGGGCCTCTT TAAAAGCTTG ACCGAGAGCA ATCCCGCAGT CTTCAGTGGT GTGATGGTCG 660 TCTATGTGTA AGTCACCAAT GCACTCAACG ATTAGCGACC AGCCGGAATG CTTGGCCAGA 720 GCATGTATCA TATGGTCCAG AAACCCTATA CCTGTGTGGA CGTTAATCAC TTGCGATTGT 780 GTGGCCTGTT CTGCTACTGC TTCTGCCTCT TTTTCTGGGA AGATCGAGTG CTCTATCGCT 840 AGGGGACCAC CCTTTAAAGA GATCGCAATC TGAATCTTGG TTTCATTTGT AATACGCTTT 900 ACTAGGGCTT TCTGCTCTGT CATCTTTGCC TTCGTTTATC TTGCCTGCTC ATTTTTTAGT 960 ATATTCTTCG AAGAAATCAC ATTACTTTAT ATAATGTATA ATTCATTATG TGATAATGCC 1020 AATCGCTAAG AA AAAAAAG AGTCATCCGC TAGGTGGAAA A AAAAATG AAAATCATTA 1080 CCGAGGCATA AAAAAATATA GAGTGTACTA GAGGAGGCCA AGAGTAATAG AAAAAGAAAA 1140 TTGCGGGAAA GGACTGTGTT ATGACTTCCC TGACTAATGC CGTGTTCAAA CGATACCTGG 1200 CAGTGACTCC TAGCGCTCAC CAAGCTCTTA AAACGGGAAT T 1241 (2) INFORMATION FOR SEQ ID NO:9: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1701 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:9: ATAAAAAACA GTTAATTAGG AGTATCTAGG TTATGTGAAG CATTCATCAC CYYCCTAYTG 60 RCAGAAAWTW TCGWTAGGCA AATTTTATAT TWTAAGTAAC TTTAACATGA ACACTTCTTA 120 AACTTTGGCT CATAATTTCA CAAAAATTAG GCTGCAAGTC ACCATATTCA TCAGATACTG 180 GCAGACACTA ACTTCTGCGG CTATGACACC AAGCAATACT GAAATCTCTT ATCTTTCCAG 240 GGGGGTTGTT CATGTATTCA GTGTTTGCAA AGAGTTCCTG CTGAGCTAAA CACAGTCCAC 300 TGTGCACTCT ACGAAAGAGT CCATGAGACA AGCATGGGGG AGGGTAGGAA GTTTAATACT 360 TTCACAATGC CTGTGGAGAC GCTGGCAGTG ATGAAAGCCT AGAAAACTCA TGAAAGGACC 420 TTTTATGAGC AGGGTGAATG TAGAGCACAA AAGCAAAGTC AGATGACCCA CTTAAAGCTT 480 TGCCTTTACT GATGAGAATT CATTCTCATT CCAGATTAGT CTCTCTCTAG AAAAAGCAAA 540 CCTTATATAA GAGTTGGAAA ATTAAGATAC AGGAAGTATA ATTCTACTAA ATTCCAGTTT 600 TTCCTTCTCA AATATCAGCC TAAGTCCTAA GGTCTGTGGC CAAAGACAGA AAATACAAGG 660 CGCTGAGAAA TATGCTATTT ATCTTGGTGT AACAATCTCT GACTGTTGGG GTTTGAGGAA 720 ATTTAAGCTC TACAATCCAT AGATCAGACC AGAAGTTTAG GGTAGTAATA TTATGAGAGG 780 AAATAGTTTC TTTCTGGAAC TTATATAAAG CAAATAACTG GTAAACCTGA TTTGCAAGGT 840 AATGACAGTC CAAGTTCCTT CAAAGCAGAG AACCACTTAT TTGCTCATTC ATTCAACTAA 900 GTTCCTTGTC TTGTGCCAGG CTGGAGAGAG AAAGCAGCTC CTGTCCTCAA GGAGCTCACA 960 TCTCAGGCAT CTTCTCACCC TCCTTTCTCA TGTTAACCAA AACATTTCAG GTTCATCAAT 1020 GAAACTCTTC ATCCAGGAGG CAGATAAAAT GGCTTCTCTT CATTTTGATT CATTTACTCT 1080 TTCTTTTATT TATTTTATTA TTATTATTTT TTTTTTTTCT GAGAAGGAGT CTCGCTCTGT 1140 TGCCCAGGCT GGAGTGCAGT GGCGTGATCT CGGCTCACTG CAACCTCTGC CTCCCGGGTT 1200 CAAGCGATTC TCCTGCCTCA GCCTCCCAAG TAGCTGGGAT TACAGGCATG CGCCACCACG 1260 CCCGGCTAAT TTTTGTAATT TTAGTAGAGA TGGGGTTTCA CCATGTTGGT CAGGCTGGTG 1320 TCAAACTCCT GACCTTGTGA TCCGCCTGCC TCAGCCTCCC AAAGTGCTGG GATTACAGGT 1380 GTGAGCCACC ATGCCCGGCC TACTCTTTCT TTTAAACAGA GAAATAAGAT GGAATATTTT 1440 TATCCCATCT TTTCTTCTGT AATTAAAAA GGAATACGAA GAAACTTGAC ATAGTCTCTC 1500 TCCTCATGTG CTCTCTTACT TCCCATCCCA ATTCCATGTT TGCTCTCTTT TTCCTCTCTC 1560 CTTCTGTTTT GTTGTGAATG AAGAATTAGG TAACTAGTCC AAACTACAG AGCTACACCT 1620 GGAGCCTAGA TTCACTGGTA GCAAATCACT AATTTTCTGA AGGTAAATGG GAGAAAATGG 1680 GGGTGGGGGG AAACTCATTA A 1701 (2) INFORMATION FOR SEQ ID NO:10: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1293 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:10: GGAGATAATA AGTATACACT ATGTGTGAAG GGGGTGTCTC TATTGTTGTT GTGGCGATTA 60 GGTGAGTAAT TTTACACCTG GTTGTGAATA AAGTCCGAGA TTGGGGGACT CACGCTTTGT 120 AGAGTCTCCC AGGACAATGG GTTTTGCCCC CGTGCCCAAT TAATAGTTAA AGGTTGGGGG 180 CTTTTCGATT CCCTTATTCC AACTGGATAG GGCTCTTGAA ATGCCCCCAA AAAAGGTTGA 240 CCCTTTCCCC ACACGTCAAA GAGGGAATTC TCCCGCTAGA CTACCCTTGA ACCTGAAGTG 300 CAGTCCCTAC AGGGTATTCT AGCTTGTTAG CATCCCCCAC TGTGAATCAA TCCCTTAAAA 360 TAAACCTATA TAAGATGTAT GTAATAGAGG ACTAATCTTT AATATAATAA GCATATATTT 420 AATATAATTT CGGTACTACC CCCTTATCTG GGGGGGGGGT GGGGGGATAT GTTCCAAGAC 480 TCCCAGTAGA TGCCTGAAAC CACAGATGGT ACTGAACCCT ACGTAAACTG TATTTCATTC 540 CTATACATGC AGGCTATGTG TTGTAATCTG TAGGGTAACC ACTAAAAGAA CAGGGTCTAT 600 AACTTGGCAA GAGGGAAAAA AGCTAGGATA GTAAAAAAGT CTATCAATCC AAAAAGCAAG 660 AAAAAAGAGA AAAAGGAACA TGCTGGCATA TTATTATAAG TATTGTATTT TATTATTAGT 720 TATTGTTAAT TTTTTACTGT GCCTAATTTA TAAATTAAAC TTTATCACAG CTATGTATGT 780 ATAGGIIFIAAT ATATATCTGT GGTTTTAGGC ATCCACTGGG GGTCTTGGAA TATAATGCTT 840 CCCCCAGATA AGAAGGTACT ACTGTAATTA TATTATATGT CATATTAAGT ATACATTAAT 900 TCTACTAGGT AGTAGCCACA TTATATATTA ATTATATTAA ATATATATCA TATAGAATTA 960 TTTTAAGGAA TTGACTCATA ATAGAAGAGG CTGGCAGGCT GGAGATTCAG GGAGGAGTTG 1020 CATTTCAAGT GCAAAGGCAG ACTGCCAGAG AATTCCCTCT TGCTTGGGGG AGGTCAGCCT 1080 TTTGTTCTAT TCAAATCTTT GAGGAAAATA GAAAGCAAAG AATATATTAA CTATATTAAA 1140 CAAACTAAAT GTTCCAATTA AAATACAAAA ATTATAAAGC CTAATAATAA AAGCCCTCAA 1200 TTATATGCTG TTTAAAAGAG ACATTTTTAA GCTTAAGGAT ATAGAAAAGT TGAACATACA 1260 AGCATGGAAT AAAATAAGCA TGCAAAATAC TAG 1293 (2) INFORMATION FOR SEQ ID NO:l1: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 529 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:11: GCTGAGGTGC ATCGCGGTGG CGGACGCTCT AGAACTAGTG GATCCCCAAA CAAAACCTGT 60 CCCTGCTAAT GATGGTAGAC CCAATCAGAT CCCCGGAGAA GCCGAAATAC GGAAACCATA 120 TCAGCATACG CATGGCATAC ATAGAACCCC ATACATGGAT TGCTTACTCA GCCAGATATA 180 GAAATCTATC TTCACGATAG AGATATATAT ATATAGACAC ACTGCATATA CAGATGTGAG 240 ATGGAGGCTC ACTCTGCCAC CCGTGCTGGA TCTACAGTGG CACAAGCTCA GTCCACAGTC 300 ACGTCGATCT GCCGGGCGTG ACCGACTGAG ATGCAGCGGC CTCGGGCGTA GCTGTGAGTA 360 CACGCACCAG TCATCGCGAC TGGCTGCAAG TGGTATAAGC GGAGGGGACA GGGTTACAGC 420 ATGACGGCTA GGCAGGCCGC AAACTGAGGA CCACAAGAGT GCCACGCTGC CCGAACGCAT 480 GCAGTGGCGA GATTACATGG GGCAGCCACT AGAGCCGCCG TATCAGAAA 529 (2) INFORMATION FOR SEQ ID NO:12: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 18073 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:12: AGCGCGTGCG CCGCTCTAGA ACTAGTGGAT CCCCCGAGGA GTGAGGAGGA CCTCAACCCT 60 ACTTCCTGAA ATGGAGCTCT GAGATGTTGG AGTAGAAATT TGGAAACCAG AGAGAGAAGT 120 AAGGGTAGTG TTGTTGCAAC ATGCATTGTA TATGGGGGGT CGGGAAGTCA CAGGAGTTTG 180 CCTCAAAGTC TTTCTCGGAG ACGGATGAGG TTTTCACTGT GATTTTCCTG GTCGTGGTCT 240 ATGGATATAG TACCTGTTAG TGACATGGAT CTTCTTAACT TCTGATGTGT CTTTTCCTCC 300 CTAGTGTACG CATACCAATT CTCTCCACAG CTTCCATCAC CATGCATTTG TTCTTTTCCC 360 TTGTTCTTGT ATTACCTTTC TGGAAAGGAA TTTTTATTGT AGGCTAATTG TTACTCCCAC 420 CAGTATTTAA CCACTGGATA TTTCATATGA TTGATCTCTT CTGATTTGGA AAATAAAAAT 480 GTAATCTCAT TATATTCATT TGATTAGTGG GGACAGTCAA CACTTCTTTG TGTATTTTCT 540 TAGCTGTTCG TTTTTCTCGT CTGTAAATTA TCTGTTTAGG TCCTTCAGAT TTTTCAAAAT 600 TGGACTGTTA TGTTTTCAGT ATTGTTATGA GTTCTTGTTT CAATTATTTA TGACAGTTCA 660 TTTTCTTTTT TAAAATAGAC TTTTTTTTTC TTAGAGAAAT AAGAAAAAAT AAAAATTAAA 720 ATAGACTTTG TGTTTTAGAG AGTTTCAGGT TCACAGCAAA ATTGATCAAA AAGTATGGAG 780 AGTTCCGGCC AGGCGCGGTG GCTCACACCT GTAATCCCAG CACTTTGGAA GGCCAAGGTG 840 GGCAGATCAC AAGGTCAGGA GTTTAAGACC AGCCTGGCCA ATATGATGAA ACCCCATGTC 900 TACTAACAAT ACACAAATTA GCTGGGTGTG GTGGTGCACA CCTGTAACTG TACCTACTCA 960 GGAGGCTGAG GCAGAAGAAT CTCTTGAACC TGGGAGGTGG AGGTTACAGT GAGCCACAGT 1020 CATGCCCCTG CACTCCAGCC TGGGCAACAG AGTGAGACTC CGTCCTAAAA AAAGAAAGAA 1080 AGAAAATATA GAGCATTCCT AAATACCACC TGTCCCCAAC ACCTGCACAG CCTCCTCATT 1140 ATCCACATCC TACACCACTG TGGTACCTTT GTTGCAATTG ATGGACCAAC ATTGACTCCT 1200 CATTATCACC CAAGCTTTGG TGTTGTACAT TCTGTAGATT TGGACAAATG TATAATGACA 1260 TGTGTCTACC ATTGTAGTAT CATACAGAAG AATTTGACTG CCCTGACAGT CCTCTGCTCC 1320 ACCTGCTTAC TCCTCTCTCC CTTTTCCTAA CTGCACAACC ACTGATTTTT TTTTTTTTTT 1380 TTTGAGAGGG GGTCTCACTC TGTCCCCCAG GCCGGAGTGC AGTGGGGCCA TTTGGGGTCA 1440 CTGAAAGCTC CACCTCCGGG GTTAATGCAA TTCTCCGGCC TCAGCCTCCC GGGTAACTGG 1500 GATTAAAGGG GCCCGCCACC AAATCGGGGT AATTTTTGGA ATTTGAAGTA AAAAGGGGGT 1560 TTCCCCATTT TAGCCAGGAT GGTCTCGATC TCCTGACCTC GTGATCCGCC CACCTCGGCC 1620 TCCCAAAGCT GGGATTACAG GCATGAGCCA CCACGCCCTA CCTTTTTTTT AAAAAACAAG 1680 GTCTTGCTCT GTCACCCAGG CCTGAGTGCA GTGATGATCA CTCCTCACTG AAGCGTCGAC 1740 CTCCCAGGCT CAAGTGATCC TCCCACCTCA GCCTCCTAAA TAGCTGAGAC TACACACACA 1800 CACCACCATG CCCAGCTAAG TTTTGTATTT TTTATAGAAA TGTGGTCTTG CTGTGTTGTC 1860 CAGGCTGGTC TTGAACTCCT GAGTTCAAGC AATTTGCCTG CCTTGGCCTC TCAAGGTGTT 1920 GGGATTACAG GCATGAGTCA CCGCACCTGG CCTTTTTTAT TTTCTTTTTT TTTTTTTAAC 1980 CAGTGATCTT TTACTGTCTC CATGGTTTTT CACATTGGCT TCTGTCACTT AGTAATATAT 2040 GTTTAAGTTT CTTCTACGTA TTTTCATGTT TTTAGCTTAT TTCTTTTTAG CAGTGAGTAA 2100 TATTTCATTG TCTGGATGTG CCATCACTTA TTTATCCATT CGCCTGCTGA AGGATATCTT 2160 GATTGCTCCC AGTCGTGGCA ATTATAAATA AAGTTGCTGT AAACATCCAT GTGCAGGTTT 2220 TTTTTAAGTG GCATAAGTTT TCATCTCATT TGGTTAAATA CCAAGGAGCA CAATTGCTGG 2280 ATCATATGGT AAGAGCTTAT TTATTTTTTT GAGAGACTAC CAAGCTGCCT TCCAAAGTGG 2340 ATGTACCATT TTGCATTCCC ACCAGCAGTG AATGAGAGTT CCTGCTGCTC CATATTCTTA 2400 CAAACATGTA GTATTGTCAA ATGTTTTGGA TTTTAAAACC AAAATCCATT TTCATAGATG 2460 TGTAGTGGTA TCCCGTTTTA ATTTGCAATT ACCTAATGAC TTGATGTTCT GTGTCTTTTC 2520 AGATGCTTAT TTGCCGTACT GTTTATCTTC TTTGGTGAGG TGTCTATTCA GGTCTTTTGC 2580 CCATTTTTAA TCTGGTTGTT ATTTTTCTTG TTGAGTTTAA GAATTCTCTG TCCTTTGTCA 2640 GATCTATCTT TTGCAAATAT TTTCTCCTAG TCTGTGGCTT ATCCTCTGAT TCTCTTGGCA 2700 TTGTCTTTCA CAGAGTAGAC ATTTTATATT TTAATGAAGT CCAGACTATC AATTATGTTC 2760 TCATGGATCA TGCCTTTGAT GTTATATCTA AAAAGTTCTC GCCATACCCA AAGTCATCTA 2820 GATTTTCTCC TGTTATCTTC TTGGCATTTT ATAGTCTTAT GATTGATATT TAGGTCTATG 2880 ATTCATTTTT AGTTAAATTT TTGTGAAAGA TAATAAGGTC TGATATGGAT TAATTTTTCT 2940 ATATGTAGCT GTCCCGTTCC AGTATCATTT GTTGAAAAGA CTATCTTGCT CCATTTTATT 3000 GCCTTTGCTC CTTTGTCAGT TGACTATATT TATGTGGGTC TGTTTATGAT CTCTGTTCCG 3060 TTCCATTGAT CTGTTTGCCT TTTCTTTTGC TAATACCACA GTCTTAATTA CCATAGCTTT 3120 AAAGTAAGTC TTGAAGTCCA ATAGCATTAA TCTTTGACTC TTCTTTAATA TTGAGTTGCC 3180 CCTTCAGAAT CTTAATGTCT CTCCATGTAA ACTTTAGAAT CAGCATTTTT ATATTCACAA 3240 AATAACTTGC TGAGATTATG ATTGAGATTG CATTGAATCT ATAGGCTTAT TTGGGAATAA 3300 CTGACATCTT GACAATATTG AGTCTTCCTG TCCATAAACA TTATTTATGA TGGGCTTCTT 3360 CTTTATGTTT AGGAGCTTTT GTTTTTTCTG TCAGATATTC CACTTCTACC TTTATGATTT 3420 CTTAATTGCC TTTTATGCTT AGAAAGTTTT TCCTCATCCT GAGCTCACAT ATTCATTTAT 3480 TTTCTTTTAA AATGTGTTTT CAAGCATTTA ATTTTTAAAC CTATGTGGAA TTTATTTTGG 3540 TATATGGAAT GAGGTGGTGG TCTAACTCCC TCCTCTCAAA TATGTAGTTA TTTTTCCCAA 3600 AACCATTTTC TATTAATTTA TCAAGAATAG ACATGTATAC ATATACATAT ATAATAGTCA 3660 GCCTTCCACT TGTTGTTTGA CCCTTGTGAA GGAAATTGTA TGAGTTTCCA ATTTTGGATT 3720 AGGCTCAGGT AGTAATTGAG CTGGGTTCTG CCAGAGATCC ATGTTAATTC ACTATCCAAA 3780 CAGAGTTATA AAATGTAAGT TTTATGAAAA TCTAACAGTA TATCACTGGT TTAATGATCA 3840 CAGCCTAGGA AGAATGGGGA AATTGTCAAA ATCTTCTGTG GATGCACCTG AAGGCCACTG 3900 CTGAACCCAT TTCCCTGCTA GGCACGGCTG CTGGTACCAG GGGCAAACTC CTGGAGTATA 3960 TATGAACCAC CTACATCTCC TTCTCTTCCC CCCCTACCCT TGAGATTTTC ATGTGTCCCT 4020 TAAGGATGTG TGTCCTACTT CCCTTGGAGA GTCACTACCA CATTGAACAC TTTAGACTGT 4080 GAGTCCTGTG AAGATGGGGC TCATGAGTGT ATTGCTCCCC AGTTGTTTCT CTAGCACTAG 4140 CTCAGTATAG GGCATAAAAA TCTGAATGGA TGAACAAACC ACTATTACTG GTGGGGACAT 4200 GCTACTATCT TACATGGTTC GAGGTGGAAT AAAGGTTGAG AACAGCTATA TAATGTGTTC 4260 CTTGAAGGGC AGCAGTACAT CAGTGCAATC AGCCTACCTT CTCCATACTT CTCACTCTGA 4320 AAACTGTAAA GCTGCACCTA GCAATCAACT TGGGAGCTTT AAAAGGGACT GCTCCCTAGC 4380 TCTCACCCAC AAAGCTGTAG TCTAGCACAG GTGACTTTTT TAAAAAAGTT TTTTGGTCCA 4440 GATGTGATGA CTCACGCCTG TAATCCCAGC ACTTCGGGAG GCTGAGGCTG GGAGGTCACC 4500 TGGGGTCAGG AGTTTGAGAC CAGCGTGACC AACATGGAGA AACCCCATCT CTACTAAAAA 4560 TTTGCCGGGC ATGGTGGCAC ATGCCTCTAA TCTCAGCTAC TCGGGAGGCT GAGGCAGGAG 4620 AATTGCTTGA ACCCGGGAGG CGGAGGTTGC CGTGAGCCAA GATCACACCA TTGCACTCCA 4680 GCCCGGGCGA CAGTGCAAGA CTCCGTCTCA AAAAAAAATA AAAAAGGAGT CCTATTAAGA 4740 CTTATTTTTA CAGGTTGGAT ATCTCTAATC CCAAAATCTG AAATGCTCCA AAATTTGAAA 4800 CTTTTTGAGC GCAGACATGA TGCTCAAAAA AATGCTCACT GGGACATTTT GGATTTCAAA 4860 ATTTGGATTA GGGACTAGGT GTGGGAGCTC ACACCTGTAA TCATAGCACT TTGGGAAGTT 4920 GAAGCAAGAG GATCAGTTGA ACCCAAGAGT TTGAGAGCAG CCTAGACAAC ATAGTGAGAC 4980 GCCGTCTCTA CAGAAAATTT TAAAAATTAG CCAGGCATCG TAGTACATGC CTATAGTCCC 5040 AGCTACTCAG GAGGCTGAGA CAGAAGGATC ACTTGAGTCC AGGAGGTAGA GGCTGCACTG 5100 AGCTATGATC ATAACCACTG TCTCCATCCT GGGCAACAGA GCAAGACCCT ATCTCTTAAA 5160 AAAAATCTGA AACACTGCTA GTCCTCAAGA TAAGGGATAG TCAGTCTTTA TAAAGACTCA 5220 ATTAGTTATT GGATATCTGA GGAAGCATGC ATATCAGGCT CCCAAAAGAT CATTGGTTTA 5280 GGCACACATT TTAATAGCTT GGAAATCCAG AATACTCTTC TGGTGACCAG CTCAGACATA 5340 GTCCTGATAA TATAGGACCT CATCTAACAT GACTCCCTAT TTTCCAGATA AGCATGGATT 5400 CCTGGTTCAT TCTTGTTCTG CTCGGCAGTG GTCTGATATG TGTCAGTGCC AACAATGCTA 5460 CCACAGGTAA ATTGTCATTT GATAAGGCTG CTATTTGAAA TGAAATTTTG CTTTCACATT 5520 TAATGAGCCA CATTTGAAAA CCGAGATGGT ATTTGAAGAA AGGAATATAA AAATTTTATT 5580 CAAAGTGATG GTAAAATAGG TGTCTTCAGA AATCTTGGAA TTGAATGCTC AGCATTGTTT 5640 TTCATACATA CATAACTGCT TTAAATAAAT CAAAGAGATT ATGTGTTCTT TCCTGAAAAG 5700 TAAAATAAAT TGTTGACATT TACAACTCTA TATATGGTTT CTGAGGAACT AAGTGAAGAA 5760 TCTTGTGTCT TTCTCCCTTA AACCGTAGTC CTTTGGAGGA GGTAGGAAAG GTCCAGCATG 5820 AGATAAAAAC GTAGGGGGTG GGTGGTGTTG AGGGGGATTG GTCTTTGCTT GGTCTCCATA 5880 TGTTTGAGAG TTTATTAAGG CTTGCTGCTT TGTGTCTCAC AGCTTTTTAG CCTCACATTC 5940 TTCATGTGCT ATTTCCTTGT TTTTTGGTGT TTGTAGTTGC ACCTTCTGTA GGAATTACAA 6000 GATTAATTAA CTCATCAACG GCAGAACCAG TTAAAGAAGA GGCCAAAACT TCAAATCCAA 6060 CTTCTTCACT AACTTCTCTT TCTGTGGCAC CAACATTCAG CCCAAATATA ACTCTGGGAC 6120 CCACCTATTT AACCACTGTC AATTCTTCAG ACTCTGACAA TGGGACCACA AGAACAGCAA 6180 GCACCAATTC TATAGGCATT ACAATTTCAC CAAATGGAAC GTGGCTTCCA GATAACCAGT 6240 TCACGGATGC CAGAACAGAA CCCTGGGAGG GGAATTCCAG CACCGCAGCA ACCACTCCAG 6300 AAACTTTCCC TCCTTCAGGT ACTAGAGATG ATTCTGTTTG TTCTTTTGCT CTTTGAGTTT 6360 AGTCTTCCTT TTATTATCTT GTTTGTGTTT TCTAGCCTTA AAATTTCTTC AAATAAGTAA 6420 AATTGCTCAA GTGAAGTAAT GAAACCTGTA TGTGGAATTT TTGGGTTAGC ATGAGTGAAG 6480 AGGAAAGAAG AAAGATTCTG GAGAATATCT TTCTGCTAGG TGGGATCCTG GTTAGATTGA 6540 GAGGACTTAA ATGTGTTTAA AGGTAGAGAA GAAGGCTTAA AAAGACAAGA GAAATAGAGG 6600 AGCTCATTGA CGATGCAAGA GACTGAAGAT GAAAAGATAC AGAGAATGAG TAATAAGATT 6660 AGGTTTGGAA AGGGAGGGAT CCGTGGAGAC CATGGAAAGG AGAATGGGTA TTGATGTCCA 6720 TGACAGTTAG ATGTGAGATA CAGAGAATGA GTAATAAGAT TAGGTTTGGA AAGGGAGGGA 6780 TCCATGGAGA CCATGGAAAG GAGAATGGAC ATTGATGTCC ATGACAGTTA GATATGGAGT 6840 GGCAGGCCAG TGGCCAGGGG TGGCATCAGG CTCTGGGAAA TGGTTACATT GCAGTGCCAG 6900 TTGTTCAGGG CCTCAGGTTG AAGCAGTAGT CCCAAGGAGA AAATCAGAGA CGTGGATCTG 6960 AGACCAGGGC AGGTAAGACA AGTTTCTGAC CTCTTTGAAC CTTAGGTACC TTGTCTGTAA 7020 AAGAGGATTA GAGATACCCT CAAAGGGCTT CTATGAGGAG TAAAGGAAAT AATCATTACC 7080 TGATTGCTAT GTAACTGTCA TCCCTTTTCT AGCAAAAATC ACTCTTTCCT CTTCTGTGTT 7140 CCCAGTTAGA TGGTGAGTGC CCCTAAGCAG AATCACATCT CGCTCATGTG GAACATTCAG 7200 GAACTGTTTG CTCAGTTGAT TCTCATTTGT TACTACAGAT GATATCTTTT ACTGCGCCTT 7260 ATAACTCAGA CCCTTCACCT GCCAGCTTTT CCCCATATTT TCTACCGTAA AGACAAGACA 7320 GCATTTGCAG TTAAGAGCAC AGTCTTCAGT GCCACACTGA GTTTGAATCC CAGCTCTTCC 7380 ATAAACCAGC CATGTTTATG GCATAGCTGG CTTACTTTAT CTCTCTACCT CGGTTTGTTC 7440 ATCTGTGAAA CAAGAATGAG TGATAGTAAT AGTTCTTACC TCATAGAGGA GATATTAGGA 7500 TTAAACAAGT TAATATGGGT AAAGCACTTA TAAAGGTGCC TACACATGGT AAGCACTATT 7560 TTTAAGTGTG AGCTGTTAGT ATTGTTGTGG TTATTGCTCT GATAGTTACC AGTAAAATAT 7620 ATGAAGGTAC CTTTAATGCA GATGGCATCC CACTATTCTT GATGAGATAG GGGACTGCAG 7680 ACAAATAATG TCTGATACTT GCTTTGTGCT TTAGAGTTAA TGTAGTTTTG TCATAGTTAT 7740 TACTGTGTGC TAGGCATCGT ACTAAGAGTT TTCTAGAATA ATCCTATGAA TTAAGTTCTA 7800 TTTTATGTTT TATAGGTGAA AGTATTTTAC AATGATGAAA CCATAATTTG TGGAATGTTT 7860 TTCAGTGTAC AGGTCATGAC ACAATTCATG AAATCACTTT AGCAGGCCAC CACTAGTTGT 7920 TTGTTTTGTT TTATTTTAAT GGATGATCCA GTTCCATGTT TATTCTTTTA ATGTTACATA 7980 CAATTTTTTG AAATTTTAGT AACAACATAA AATGTTGGGT TGTGGCCATT GCTTAGGGAG 8040 AAAGGCAGGA TAACTTGTAC AAACTGTATG AGTGAATGGA AAAGGTGGAG ACTGTAACAC 8100 AGGCCTGACT GACTGAACAG CCCATGTTCT ATTGTGTACT GTCTTTCATT TAACAGTTCT 8160 GTGACATGAC CATGGATAAT CATCTCCTTT TAACAGATGC TTGATTTCAG ACTGTATATA 8220 GAGGTTAAAT GATTTGTTTT AGATCTCAAG GCTGACAAAT TAGGCCTATT TCTCACTTTT 8280 GCGGTCTTTC CACTCTGCTT GTAGGGAACT TAGTTTTCCA TAAACTGACT TAGGTCCAAA 8340 TTGTGCCACA GCTAAGAATC TAGTTATTGT ACATTTAACA CAGTTCACGT CATAGGAGGC 8400 TGAGACTATG TTTCTCTAGT GGCGTTTATT CAAGATGAGT AAAACACAAG AAACCATTAT 8460 CGCACATGGG AATTTCATAG TCTTAAACCC CACATCCCAC TTATCACCAC CATTTACCAG 8520 TCCTCCTGTA ACAGTTACAA TTTTTTATTA AATCAGTATT TGATGTATAT TATTGTAATT 8580 ATGAAATATT CATTGCTGAG CTATAAGTAT AAATGGATTG TTTTTCTTGT ACAGTTTTTT 8640 TTCTGGATTT AATACTTACC TTATTTTTTG TTTATTTAGT TTTCTATTTA GTCAGGCCAG 8700 GCACACTGGC TAACACCTGT AATCCCAGCA CTTTGGGAGG CCAAGGTGGA CAGATCACTT 8760 GAGCTCAAGA GTTTGAGACC AGCCTGGGGA ACATGGTGAA ACCCCATCTC TACAAAAAAT 8820 ACAAAAATTA GCTGGGCATG GGTGCATGTG CTTGTAGTCC CAGCTACTCA GGAGCCTGAG 8880 GTGGGAGGAT TGCTTAAGCC CAGGAGGTTG AGGCTGCAGT GAGCTGTGTT CATACCACTG 8940 CACTCCAGCC TGGGTGACAA AGCGAGACCA TGTCTCAAAA AAGTTATTGC TACTCAATTC 9000 TTACCATGCT CTCCAGAGCC TCTCAAAACA GCTTTCTACA AAGTGAGATC TGTTAGATAA 9060 TCTATTTCTT TTTTACCTCT AGAAATTCCT CCTGAGCCCT CCATTGTCTT ATTCCAGTCT 9120 AGGCTTGTCG ATCTCTAGGG CTACTACACA GATACATCAG CCTGAGATTT CCCTTCTCTG 9180 TCATTCTGGG AATTCCCCTT GCTGCTGCTT CCTGACTTCC ATATTGTCTT CCTTTTTGTC 9240 TTCTCATCAT TCGGTAGATT CCTGAGAAAA GGGGTCCATG GGAGGCAAAT TGCATCCTTA 9300 CATATCTAAA AATATCTTTA GGGCTGTGCA TAGAATTTGA GGAATATTTT TCCCCCAGAA 9360 TTTTTAAAGT AATGCCCTAA CTGACACCTG TTTACCAGGT TTGGAGGATT TTACTGCTAT 9420 CTTAATCCCT AATTGTTTGT ATGCTTTCTA GGATCTTCTC TTTATCATCA GTATCCTGAA 9480 ATTTCACAGA GATGTATCTT GATGTGGGTC TTTTTCGTTC ATTATTATGG ATACTTAATA 9540 GGCCCTTTAG AGCCTTGATC TTGCATTTCT GAAAATTTTC TCCCATTTCT TTGAAACCTT 9600 CTCCCCCTCT TCCTTTTTTT TTTTTCTCAA ATTCTTAATA TTTGGATATT GGATGTATCC 9660 TGAATTAATT CTTTAATCTT TAAAATTTTT CCTTTCTGTT GATCTTTGCT TTGAGTCTTT 9720 TTCTCCTTTT AAAAATAAAC AAAGGCCAGC TAGGCACAGT GGCTTATATC TGTAATTCCA 9780 GCACTTTGGG AGGCTGAAGC AGGAGGATCG CTTAAGCCCG GGAGTTTGAG ACCAGCCTAA 9840 GCATCGCAGC AAAACCTCAT CTCTACAAAT GATTTAGAAA TTAGCAGGGC CTAATGGCTC 9900 ATGCCTGTGG TCCCAGCTAC TCAGGGCTGA GGCAGGAGGA TTACTTGAGG CCTGGCAGTT 9960 GAGGCTGCTG CAGTGAGCTG TGATCGCACC ACCGTACTCC AGTCTGGGCA ACAGAGGGAG 10020 ACCTCATCTC AAAAATAAAT AGGCCTGGTG TGGTGGCTCA CTCCTGTAAT CCCAGCACTT 10080 TGGGAGGCCA AGGCAGGTGG ATCACTTGAA GCCAGGAGCT CAAGACCAGC CTAGCCGACA 10140 TGGCAAAACC CTCTGTCTAC CTACTAAAAA TAAAAAAATT AGTCAAACGT GTTGGCATAT 10200 ACTTGTAATC CCAGCTACTT GGGAGGCTGA GACATGAGAA TTGCTTGAAC CTGGGAGGTG 10260 GAGGTTGCAG TGAGTCAAGT CCCTGCACTA TAGCCTGGGG AACAGAGTGA GACCCGAGAC 10320 TCTATCTCAA AAMAAnAAAA TCAGTGACAA GTAAAAAGGT AGAATACCTT TTTTTTTTTC 10380 TTTGAGACAG TCTCACCCTG TCGCCCAGTC TGGAGTGCAA TGGCGCAGTC TCGGCATACT 10440 GCAAACTCTG CCTTCAGGGT TCAAACAATT CTCCTGCCTC AGCCTCCTGA GTAGCTGGGA 10500 TTACACATGC CCACGACCAC ACCCAGCTTT TTTTTGTATT TTTAGTAGAG ACAGGTTTCA 10560 CCATGTTGGC CATGCTGGTC TCGAACTCCT GACCTCATGA TCCACCTGCC CCGGCCTCCC 10620 AAAGTGCTGG TATTACAGGC GTGAGCCACT GCGCCCAGCC TAGAATACCT TTTAAAAATA 10680 AATAAATAGG CCGGGCGCGG CGGCTCATGC CTGTAATCCC AGCACTTTGG GAGGCTGAGG 10740 CGGGCAGATC ACGAGGTCAG GAGATCAAGA CCCTCCTGGC TAACATGGTG AACCCCATCT 10800 CTACTAAAAA ATACAAAAA AAATTAGCTG GGCGTGGTGG CAGGTGCCTG TAGTCCCAGC 10860 TACTCTGGAG GCTGAGGCAG GAGAATGGCG TGAACCCAGG AGGTGGAGCT TGCAGTGAGC 10920 CGAGATTGCG CCACTACACT CCAGCCTGGG CAACAGAGCA AGACTCTCTC TCTAAATAAA 10980 TAATAAATAA ATAAATAAAT AAATAAATAA CTCCTTTTAC AAAAGCATAT ATATTCATTT 11040 TTTCCATTTA TAATATAAAT AATAGATATG CTGAGTTGAT TTCTGCATAT TGCTTTTTCA 11100 GTTACCCTAT CATACTTGCT CTTTGTTTTA GTAAAGAGCT GCTGTATTGA AGGATATACC 11160 TTAATCTCTT TATCCAGTTT CCCCATCAGT GGACACTAAG ATTGTTTTCA GAGTACTCTT 11220 ATAAACAATA CAGTTTGTCA TTTCAGACAC ATATGAGAAT ATTAGCAGGA TGAATTATTT 11280 TAAGTCTGCA TTTATAAATT TATGGATATT GCCACATTTA CCTCTGCTAG GAAGTCTATT 11340 CCTATTAACA ATATGTCAAA GTGCCTATTT TTCTAAACTC TCTTCAGTGT GGTGAATTGT 11400 TAAACTTGGG GATCTCTGCC AATCTGACAG GTGAAAAATA ACATCTCAGT GTAAGTTTAA 11460 TTTGCATTTT GCTGAGATTG AGCAATTTTG TGTAATTTAA AAGATCATTT ATTTTTCTGA 11520 GCATTCTCTG TTGATATTCT TTACCCATTT TTATTAGAGT GTCAAGGTTT TCCTGACTCG 11580 TTTGTAGATG TTCTTTGTAC GTTTGGGAAA TGAGTCCTTT GCCTATGGTA AAACTGCAAA 11640 TGTTGTTCCC TAGGTGGTCA TCTAGATTTT CTGCATTGCA GAAGATATCA TTAGCTATTT 11700 TTAATTTTTT TAATTTAAAT ATTTCTCAGT TTAGGTTTTC TAGGAATTGG GTCATATCTA 11760 GGAAGGCTTT CCTTACTCCA AGATTATAAA AATAATTTTC TTCTGGACTT CTATGGTTTC 11820 GTGTGTGTGT GTGTGTGTGT GTACACGCAC TTAAGTCTGT CTCGAATTTA TTCTGATGCA 11880 GAGTGAGCTA TGGATCTGTT TTTCCCCAAA TATCTAACTT GTCCCAATAC CCCTTAATAA 11940 TTTATTTTTC CTCATTGATT TGAAATGCCA CCTATCTTAT ATATTGAATT CAGATATTTA 12000 TTTACCTCTT CATATGTATT TGAGTATTTG GGAACATTCA TTTTATTTTC TATTAATCTT 12060 TTTCTCTGTC CATGTGCAAA GCCTCACTGT CTCAATAATT GTAACTTTGT AAAGTATTTA 12120 ATATCCAGTA AAATGAGTCA TTCCTTGTTA ATTTTATTTT TCAGAATTTT GTTAGCAATT 12180 CTTATTATAA ACATTAGAAT TAACTTGTCT AGCAGGAAAA AAAGTTTGTA TTGATCATGT 12240 TAAATACGTA GATTAACAGA GAAAATGGCA TCTTACAGAT GTTGAGTCTA ACTATCCAAG 12300 AATGCAATAT ATTCCATTTT CTGAAGTCTT TTTTTTTTAA ATCTTCTGTT TTTGTAATTA 12360 TAAATGGAGC ATTTTCTTCC ATCAGATCTT CTAACTGGCT GCTGTTGGGG ATATGAAGGC 12420 TACTGATTTT TGTAGAGACA TTTTGTACTG GCCACCTTAA ACTCTCTTAG TATTGGAAGT 12480 AATTTTCTTC ATTAATTTTT ATGGCTTCAA GTCATCTCAT CTGCATATAT CTTCCAAATT 12540 TTTAGAACTT TCTTTTTCTT CTGTTTAATC GCATTGATGA ATACCTCCAG AACAAAGTTA 12600 AGCAGCTGGT AAATGCAGAC AGCATTCTCT TGTATCTGAC ACTAAGGAGG ACACTTTCAG 12660 TGGTTTTTCA TTATACGTGG TACTGACTCT TGAGTTGAGA TAAACATATT TTATTGTGTT 12720 CAGGATTTAA TGAGCGTTTA TGTTAGGAAT GGGTGTTAAA TTTTGCCAGT TGCCTGTTCA 12780 GGATCAATGA GAAAGATCTG AATGATTTTT TTTCTCTTTT GGTCTGTTTC TATGGTGGAT 12840 TCTATTCCTA GGTTTGTTTG TTTGTTTGTT TATTTTGAGA TGGAGTCTGT TACCAGGCTG 12900 GAGTGCAGTG GCGCCATCTC AGCTCACTGC AACCTCCACC TCGCGGGTTC AAGTGATTCC 12960 CCTGCCTCAG CCTCCGAGTA GCTGGGACTA CAGGCACGCA CCACCATGCC CGGCTAATTT 13020 TTTGTATTTT AGTAGAGACG TGGTTTCACC ATGTTGGCCA ACCTGGTCTC GAACTCCTGA 13080 CCCCATGATC CTGCCTCAGC CTCCCAAAGT GCTGGGATTA TAGGTGTGAG CCACTGCGCC 13140 CTGCCAGTTT TTATTTATTC ATTTTTTAGA GACAGGGTCT TGCTCTGAAT TAATTCTTTA 13200 ATCTTCTTAA TTTTTCTTTT CTGTTGACCT TTGCTTTGCT TTAAGTCTTT TCCTTTGAGT 13260 CATCCAGGCT GAAGTACAGT GGCACGATCA TGGCTCACTG TAACCTTGAA CTCCCAGACT 13320 TAAGCAAACC CCACCTCAGA CTTCTGAGTA GCTAAGGACT ATAGGCGCAT GTCACCACGC 13380 CCAGCTAATT TTTAAATTTT CTCAGAAACA GGGACTCACT GTGTTGCCCA GACTGGTCAT 13440 GAACTCCTGG CCTCAAGCAG TCCTCAGCCT TAGCCTTCCA AAGCACTGGG ATTATAGGCA 13500 TGAGCCAAGG CCGCCCAAAC ATATTGTATC GTTCCTGTAA CAAGCTGTTG CAGTCTATTT 13560 GATATTATTT CTTATTTTTT TCATTTAGAA TTTTCTCTGT CTAGATATTC TCAAATTATC 13620 TCTAAATGAG ATTGATCTAT GTTTTTCCTT TGTGTGTGTA TTCTTTTTGA TAAGTTTTAG 13680 TTTTTAGTGT TTTGTTTTGC TACATGGAAA GGATTTGAAA GTTTACACTA AAAAATATGC 13740 TTTTTTTTTT TAAGACAGGC TTTTTCACTG TTGCCTAGTG CTGGAGTGCA GTGGCATGAT 13800 CTCGGCTCAT TGCGGCCTGC ACCTCCTGGG CTCAGGTGAT CCTCTCACCT CAGCCTCCCA 13860 AGTAGCTGGG ATTACAGGTG TGTTCCACCA TGCCCAGCTA ATTTTTTGTA TTTTTTTGTA 13920 GAGATGGGGT TTCGCCATGT TGCCCAGGCT GGTCTTGAAC TCCTGGGCTC ACATGATTCT 13980 CCTGTCTTAG CCTCCCAAAG TGCTAGGATT ACAGGTGTGA GCCACCACAT CTGGCCATTT 14040 CATTCATGTT TTCAAATGTA TTTGAATGAG GAAAAGTTCT CCCTTGTGAT TATTTATTAT 14100 AATAGCCTAC AGAGCTATTA ATTTTTAAAT TTTGTTTACT TTATGTCTCC TTTTTTTTTT 14160 TGTTTAGGCT GAATAACCAT TTATTTCATA GGTTTATTGC CTTTTTTCTT CCAAAGAACT 14220 TGCTATTGTG CATTTATAGT CCTTTTATGT TTACGTTTTC TATTTCATTG ATTTTAACTT 14280 TCTACCTTCT TTAGATTTAT TTTGTTCTTT TTCTATCTTC TTGAATTGAG TGTGCTTTAA 14340 TTGCATTCTT TCCAGTTAAT TAACATATTT AGTGCTGTGA ATTTTGAACA AGCACAGCTT 14400 TAGCCACATC CCATAGGTGT TTCTATAGGC AGTTGTATTA GGATGCGCTA TAAGCTGCTC 14460 TGACAAAGAT ACCAAAATTC AGTGACTTAA ATAAGACCAA AGTGTCTTTC TCTCCCCAGT 14520 TACATTCCAG AGGTAGACAG GGCCTTCGTC TCAGTAGGGA CCAAATTCCT TTCCTCTTGT 14580 GGCCCTGCCA TCCTAACAAT ATTGCCCTTA TCTGTTTGGT TAGAGATAGT TCTCACCATT 14640 GGGTTCTAGT TCCAACCACT GCGAAGGACA AACAAAGGGA ATAGGGGCCA TTTCTCTTCC 14700 AAAAGATGTG ACCTGGAAGT TACTCACATT GCTTTAGCTC ACATCCCGTT GGCTAGAATT 14760 CATCACATGA CCACACCTAG CACAAAGGAG TCTCAAATAT AGTCTGCCAG GAGAGCTTGG 14820 TGCTCAGCTA AAAAACAAAG GTTCTGTATC AAGGCAAGAA GAGAAAGAGA CTGATCTGAG 14880 GGGAGGAGAG TTGGCAGGTT CTGTCACAAA ACTTCTCGTC ATTGTTATTT TTAAGGTATT 14940 TTTCCATTTT GGGTTTTTTG TTTGTCTGAT TTTTTTTTTT TTTTTTGAGA TGGAGTCTCG 15000 CTCTGTTGCC CAGGCTGGAG TGCAGTGGCG TGATCTCTGC TCACCGCAAG CTCTGCCTCC 15060 TGGTTCACGC CATTCTCCTG CCTCAGCCTC CCAAGTAGCT GGGACTACAG GCGTACACCA 15120 CCACGCCTGG CTAATTTTTT TTTTGTATTT TTATTAGAGA CAGGGTTTCA CTGTGTTACC 15180 CAGGATGGTC TCATTCTCCT GACTTTGTGA TCTGCCCACT TCGGCCTCCC AAAGTGTTAG 15240 GATTACAGGC GTGAGCCACC GCGCCCGGCC GTCTGTTTGA TTTTTGAGAT GGAATCTCAC 15300 TCTGCCCCCC TTCTGGAGTA CAGTGGTGTG ATCTTGGGTC ACTGCAACCT CTACCCTCCC 15360 AGGTTTAAGC AATTCTTGTG CCTCAGCCTC CCAAAGTGCT GGGATTAAAG ACGTGAGCCA 15420 CTGTGCCCAG CCCATTTTGG TTTTGATTTT TTTTTTTCTT TGAAATAGAG TCTCGCTCTG 15480 TTACCTAGGC TGGAGTACAG TGGCATGATC TCGGCTCACT GCAACCTCCC CCTCCTGGGT 15540 TCAAGTGATT CTCGTGCCTC AGCCTCCCAA GTAGCTGGGA TTATAGGCAC CCACCACCAC 15600 GCCCAGCTAA TTTGTTTTGT ATTTTTAGTA GAGACGGGGT TTTACCATGT TGGCCAGGCT 15660 GGTCTCGAAC TCCTGACCTC AGGTGATCCA CTGCACCCGG CCTCATTTTG GTTTTGATTT 15720 TTATTTTCAA ATGTTTTCTT ACTTTGTCAA TTTCTAATTT TATTGCATTG GGACAAAAGA 15780 ATATTGTACT CTTTCTACTG TTGGGGTTTA TAAGGGCTGT GGATATTTCA CTCGCCTTTG 15840 AAAAGAAGGT TTTCTCTGTT AGTCTGTAGA GTTTGGTATG TACCAATTAG ATTTTATTAC 15900 TTATCATTTT GGTCTTTTGT ATCCTTACTT AATTTTGTCC TCTTGAATTT TAATGGAGCA 15960 AAAGACATAA AGTCCTCTAA TAACATGCGT TCTGTTTGCA TTCTCATACT TTTTATGAAT 16020 ATTGATGCTG CACTATTTGT GTACCCAGGG AGAAGGCCAG ACCACTGTCC AAAGTTTAGT 16080 GAATCTGGGC AGCCTTGTTT CCCAGTTGTT GGAGGATGCC TCATGGAGGA AAGCATTCCT 16140 AATCCTGGAG CTTGTTTTGT TGTACTCTAA TTGAATTGTA ATGTGTTTCT TTAACCTGAA 16200 TGAATGTTTC TATTTTTTAC TTATTACACA GGTAATTCTG ACTCGAAGGA CAGAAGAGGT 16260 GAGCTGCTCA CCTTATATCT GTTGTTCCTT TTACACAGTG TACAGTATTC ATTTATTTCC 16320 TCTGCTCACA GTCTGTGGTA ACCGTGTGCA TCTGTGGCTG TGTTGTTTGT TTACTTTCCC 16380 TTAAGTTATT TCCATGTTAA TCTCATGGAG AAGAGCAATA GAAACAAGTA CTGTATTCAG 16440 TATGTTTTTT AATATAGACT ATGGATTCTA ACAGCTATGA TGTATTTTAA CAAGTAACAA 16500 AATATATCTT ACTTTGACAT GTCACTTTGT TAACATTACT TTTTGGTGAT ATTAGGTCAT 16560 AATTTCTATA CCATTAGTTA CTTCTGATTT CTAGGCCACA GTTCCCTTTA AATATTCTTT 16620 GTGTTGTTTT TCCCCTAGTG TATAAAATGT CAACCCTTTG TGGCTTTATA TGGATTTTAT 16680 GGATTTTCAG CCCTTAAATG TAAAGTCTCT ATGGCCTGAG ATGTTGTGTC TGTGGTTTAA 16740 GCTGGACTGC TGAGTCCCTG GTCACTAGAG AGTAGGGGGA CATGGGTACT TGTCTGCAGA 16800 AGTGTGGCAC ATTTTGCCTA GAATGACAGT AAGGCTGCTA TCAAAGAGCA TGAGAGAAAG 16860 AGAAAGAGAT CATCTAACAT TCTAAGAAGT GATTATTACA TTTGAGTTTT AAAAATGTTA 16920 CTATTCGAAG CAGTGTTTTT ATCATAATTT TCTATTTTAT CAAATCAGAC TTGAGTTTTT 16980 TTTCTGATTC TGTTATTTAA CCATACACAA TTTTCCCTGT GTAATTAAGT AATGGAACAC 17040 TTGGAGGCAT ATGAAGTCCC ACTAAGTAGG GAGCATTTGA GTCAGAAAAG TGGGTACTCT 17100 CTTCCTTTAT GTGATGTCCA TCTGCCATTG TATTTGGTAA GGAATAGTGA GGTGTTACCA 17160 TACTGTGTAC AGATTTCCCT CACTTTTCCA CCTCTCACTT TCCTAAACTT GGGAACTAAA 17220 CATTGGATTA ATACAGTGTC TTTGCTGTTC AGATTCACTT GCCAGATTTT ATCAAATGTA 17280 GACTTAAATA GGTTTTATTG TGATAGATAT TTACTTGCTC CCTAAAACTG CTCTCTTAAC 17340 CAGCCTTACA ATAAAGTCAA AAGTCAAAGT GGTAGGCTTC AAGATGAAAC ATAAGATCTG 17400 TTGACTCCTT CCTCTATTTA GTATATATTT TCATAATATT CAGCCTTTTC TTGCCCCAGA 17460 TATCATATCT ATTTTACCTA CCCAATATTT AAGTAGTTTC CATGTTGTGA TTAAGAAAAC 17520 AAAATTACCA TAATTACCTA GATTATTGCT AATTGTGACA TATGTAAAGT CTATTAATGT 17580 AATAAATCTC CTTTCTTAAG TCAAAAAATA ATTTTGTGTA ATTCCAAACA GGAAACTGAA 17640 AAGGCATAGG TATTCTCAGC AGTCTCTAAA GTCCCAAAAT CTAATGGCAA TTTTACCAGA 17700 GCAGATCTTT AGAAGTATTG CTATAAATTT GGATATCCCA TTCTAATTTT AAGCCAAATG 17760 CTTTTTGAGA AATAAGCCAG CTGTTTGGAA ATGCTTGTAT TATAATCGGT TTGATAAGCA 17820 GTTATGTCTT ATGCAGATGA ATTAGGGGCT ACCTGTTTTT ATGCACTGGT CTTTGGGGTG 17880 CTTTTGAACA GTAGTGTCTG ATGTTTTAAT TGTCAAAGCA AAAAGAAATG AGAGGGAGGG 17940 CAACTTTTCT TCCTCTTCTG AATTCCAGGA AACTGGTTAT TTTCTCATGC CATATGATTT 18000 TAAAATATAT TCCCAGCCAG GTGCAGTGGG TCACGCTTGT AATCCCAGAT TTTTGGGATG 18060 CCAAGCGGGG GGA 18073 (2) INFORMATION FOR SEQ ID NO:13: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 7505 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:13: TCCGAGCTCC ACGCGGTGGC GGCCGCTCTA GAACTAGTGG ATCCCTCTGG TGGCCCATTG 60 AGAATCAAAA CTTGCAGTGA GTGACTCTAT AAAATGGAAA ATTGAATCAA GTCTGAAAAT 120 GATCCACATA GTTCTACAGC AGGGCTGGAC ACCGTGGTCA GGACCTCAAT ATATTCTGCT 180 TCCACAGAAT TCAGACAGTT CAGAGTTTGG TGAATTAACC TCAAAGGCAG CAAGATATCT 240 GTCCCGGGAG TCAGCAGGTA AGCATAGCAG AAATGGCTGG AGCAGCGGGA GCCTGCTTTC 300 CTTCTGTTGG CTGCTAGCGT CCACTCCATT ATAGCTCCTG ATGGAAGATT TCTACAGAGT 360 GATGCCTCAG AATCTTCCTT ATACCTTTCT TCCATGATCC TTGCACCTCT TTTTCTAGAT 420 TTGCCCACAT TCTTATGTGC AAGTAACTAG ATATACATTA TCAGACAAGC TAGCAGACCT 480 GCATATATCC ACTTCCCTAC TTTTCCTATA ATTTCTTCAC CTGAACCTCT ATCATTCTTC 540 TCTTTCTGTG TTGACTCTGG TGTTAACCTT GCAGGCAAGT TGAGCGTGGG TTTGGTGTCA 600 CAGTGAAGGA CTAAGGGAAT AGTTAGCCTT CTATTTATTA ACAAATCTTC CCTTTGATGT 660 CTGGATCAGT GTCTCTCTAA TAGGAATTAT TGGCATGTTA AGGCAAAGAA CATATGCTTA 720 TTGAGTGCTG ACTGATTGGG GTTAATACTA ATTTGATACT ATTAAGGTGT GGGGCCCAGG 780 AATGCCAAAA TTCTACCTCA ATGTAGAGCC ACCATTCCCC TTGAGGTAAC CTAGGTGGGA 840 TAGATATACG TGTAAGGGCT AATGGAAGAT AGGGAATCAA AGTATCACTT TATTTTTTAT 900 TTTTATTTTT TATTTAATTT TTTTGAGATG GAGTCTTGCT CTGTTGCTAG GCTGTAGCGC 960 AGTGGCACAA TGAAAGTATC ACTTTATTAT TATCTGAGCT TGTGCCCTAA ACTTCACTGC 1020 AGAATATGCT GGTAAAATGG ACTGGATTAC AGGATTTAGA GGCAAGGTCC ACAGGTCAGG 1080 ATAAGAGGTA AAGAGGGAAA TCTTTCTCTC TTCCTAAGCC CAAACCCTCC ATGACAATTG 1140 AGATTAAAAA AAAAAAATAA ACTGATGAGA GAATCCAAGC ACAGTTGATC AAAGAGGAAA 1200 GAGAAATGAT GATGTTTCCC TCTTTCTTTT TCATGAGAAA GTGGCTCTCT TATTGATCGG 1260 CTACTTGATT AGAGAAACAG TGGGGGAAAG AACTGCCATA TCCACATGTG CAATTTTTTA 1320 AAACACACAG TGATTCTGAA CACTAGTATA AATTCCCAGT CAGTGTTCTG GCCATCTGAC 1380 TACTCAGGTT ATAATACCTA ATTTTTACAA GGGAGTTGGG AAGTGTGCCA AACCTGTAGA 1440 AGTCTATATC TACTGTATTC AGATTTTATA TGCATTATTT TATATAACCT TTTGACCTCT 1500 CTCCTCTATC ATCACTTGAG TGATTTCATC CAGCGTCATC ATTTAACATA TTTTAAATAA 1560 CTCTATATAC TGATAATTCC CAAATTTATA TCTCCATCCC CGATTGTTCT CCTAACCTCC 1620 AGCCTCTAAT ATCCAACTGC CTACTCAAGC CTCAGCAATG GTGAGCGCCC CTGCCCCAGC 1680 CTCGCTGCTG CCTTGCAGCT CGATCTCAGA CTGCTGTGCT GGCAATGAGC GAGGCTCCGT 1740 GGGCGTGGGA CCTTCCGAGC CAGGCGCAGG ATATAATCTC CTGGTGTGCT GTTTGCTAAG 1800 ACCGTTGGAA AAGCACAGTA TTAGGGTGGG AGTGACCCAA TTTTCCAGGT GTCGTCTGTC 1860 ACAGCTTTGC TTGGCTACGA AAGGGAATTC GCTGACCCCT TGCACTTCCT GGGTGAGGCA 1920 ATGCCTCGCC CTGCTTCGGC TCATGCTCAG TGCGCTGCAC CCACTGTCCT GCACCCAGTG 1980 TCCGACGAGC CCCAGTGGGA TGAACCCGGT ACCTCAGTTG GAAATACAGA AATCACCCGT 2040 CTTCTGTGTC CCTCATGCTG GGAGCTGTAG ACTGGAGCTG TTCCTATTTG GCCATCTTGG 2100 AACTGCCTTG CATTCAGTTT TTAATATCCA ACTGCCTATA CGATATCTTC ACTTGGATTT 2160 TGAATAGGCA TATCAAACTT GTCATGTTCA AAAGTGAGGT TCTAATCTTC CCTCCCAAAC 2220 CTGCTTCTCC CATGGCTTTC CCCATCTCAG TAAATAGGAA TTTCATCCTT CCAATTGCTC 2280 ATGCCAAAAA TTTGGGAGTT ATCCTTGACT CTTCTCTTTC TCACACCCCA CATTCAATCC 2340 ATCACCACAT TCTGATGCCT CTATCTTCAA GATATACTTA GACTTTCACC ACTTTTCTTC 2400 ACTCTGCAAT TACCACTTTG GTCCAAGCCA CTGTTATCTC TTTCTTGGAT TATTGTAATA 2460 GCTTCCTAAT AATTTGTCCC CTTTCTTCCA CCTTTGTTTC CCCTACAGTA TAATCTTAAC 2520 GAAGCAGCCA GAATGGTTGC CTACAAACCT TTAAAATGGT AAGCCAGAAC ATGTAGGTAT 2580 ATTCAAAACC TTCCAATGGC TTGTCATGGA ACTAAAAGTC TCTACATTGG CCTATAAGAC 2640 CCTATGTCAT CTACCCCTAG TCTCCTCCTT TCTAACTTCA TCTCCTGCTA TGCTGTCCTT 2700 CAACTCACTC TGCTCCAGGT GCTCTGGCCT CCTCAAACAC ACCACACACA CTTGCAGCTC 2760 ACAGTCTTGG CACTTGCTGT TCTTCTCCTC TAGGACCTTC TTCCTCCAAC TGTCTGGTTC 2820 ACCCACCCCT TCCTTCTGGA TTTCTGCTCT GATGTCATTT TATCAGTGGG CACTTCCCAA 2880 TTTCTCTATT TAAGACCACA ATTCCAGGCC AGGGTGGTGG TTCATGCCTG TAATCCCAGC 2940 ACTTTGGGAA GCCGAGGTGG GCAGATCATG AGGTCAAGAA TTCGAGACCA GCTTGGCCAA 3000 CATGGTGAAA CCCCATCTCT ACTAAAAATA CAAAAAAAAT TAGCCAGGTG TGGTGGCACA 3060 TGCCTGTAAT CTCAGCTACT TAGGAGGCTG AGGCAGGAGA ATCGCTTGAA CCTGGGGGGC 3120 AGAGGTTGTA GTGAGCCGAG ATTGCGCCAC TGCACTTCAG CCTGGGCAAT AGAGCGAGAC 3180 TCTGTCTCAA AAAAAAAAAA AAATTTGCTG TTATTTCCTA TACTATTTTT GTAAGGCAAG 3240 GACCTTATTA TTTTCCTTGA TAATACCTCT CACACTTTAT AATTACATAT TTGACTTTGT 3300 TGATTAATGA ATATCCCTCC TTTATAGCAT AAATTCCACA AGAGCAAGGA TTACATGTCT 3360 GCTTCATTCT CACTGTACAC CTAAAACCTA GCACAGGGTC TCACACATAA CAGGCACAAA 3420 ACAAACAATG GATTACGTTG AGCCAAAGAA CAAAAAAAAA TAGTAATTTA TCACTAAATG 3480 TCTTTGTTAA ATTCCAACAA CAGGGGGCAG TATATCAGGT ATTATAAGAA AGTAATTAGG 3540 CACATCCCAG CACTTTGGGA GGCCGAGGCG GGTGGATCAC AAGGTCAGGA GTTCAAGACC 3600 AGCCTGGCCA ATATGGTGAA ACCCCGTCTC TGCTAAAAAT ACAAAATTAG CGGGTGTGGT 3660 GGCACACCCC TCTGGTCCCA GCTACTCAGG AGGCTGAGGC AGGAGAATCG CTTGTACCCA 3720 GGAGGCGGAG GTTTCAGTGA GCCAAGATCG TGCCACTGCA CTCCAGCCTG GGTGACGGAG 3780 <BR> <BR> <BR> <BR> <BR> <BR> <BR> CGAGACTCTG CCTCAAAAAA A AAAAAAAA AGAAGAAGAA GAAAGTAATT AGGCACCTTT 3840 GGCTTAAGAC ACTGGGCTAA ATCCATGAAT TTACTTCATC TTCCCCCAAA GCACACTGAC 3900 ATGGTAGAAG AAATATAAAA ATACTAATGA ATCAACAGCA TATCTGAAAG GCAGCAAACG 3960 GTGGCATATG TAGATCAGAA TCTTTGAGAG ATTTCTGGAA GACAAAACAG ACCAGACTCG 4020 ATGTCCAAGA GATCAAACAG AGCCAAAGAG CCTCCAGCTG AAAACTAAGT ACTAGTTCTA 4080 CCAGTTTGGG CCTGGAAACA CCTCAAGCTC AGAGGGAATT GGGACTGGGG TTGAAAGTGG 4140 ACCTTGAGGT ACCAGGATGG TACTTAAGCA AAGGCCTGCC AACCCAGCAC CAGTACACCC 4200 ACAGCCCAAA TGACAAGCGG GGCTTCCCAT CTAGACTCAG CTGGAAAAAC AGTGCTCTAC 4260 ACAGAGTAGA GAGTTTGTCA CAGAGACTGG TAAGGGCTTC TTTTTTACAA AACATATGCT 4320 GCATATATAT TTTCTCAACG TCACACTAAT GACATTTTGG GCTATACAAT TCTCTGTTAT 4380 GTGGGTCTGT CATGTGCACT GTAGGACATT TAACAATATC CCTAGCCTCT AATTATTAGA 4440 TGTCTGTAGC AAATTCCCAA TTTTGATGAC CAAAAGTATC TCCAAGCATT GCTAAATGCC 4500 TTTGTGGGGG AAATAGCCCC CAGTAAGGAA CCACTGGTCT ATACTCACGC CATTCTAACT 4560 GAATTCTTTT AAGGCAAATC CGAGACCTAG CATTTCAAAT GCAATTACTT AGGTATGTAT 4620 CACCAAGAGA TCAAGATTCT TAACATAAAC ATAATACTAT TATCCAATTT AAAAAGTAAC 4680 ACTAATTCCT TAGTATCATC TAATATTATT CAGTTACTGC TTGAATTTCC CTGAGTGTCT 4740 CATAAATGCT TTTTTTTTGT TTTGGTTAGA ATTGACACCA GAGCAGGTCT ACACTGCATA 4800 TGATTGTTAA GTATATTGGG TCCACAGAAG GTCTCCTGGG GCCTGCAGAC AGAAAAAAC 4860 CATAGTAGTG CCCAAGCTAA TTCTAGGCAA CCACAAGAGA GGAAAGGAAA AAGAAAACGG 4920 CAGCTCGCCT AGAGGATAAC TGCACCCTGC CCCGATTTTC CTGAGCCATC ACTGAACCCC 4980 TTCCTGGTTT AGGACGTATG TCCATGTTTG TCTTCTGAAG GGATGAAGGG ACACCTATTG 5040 TGAGCACAGT CTAAGCCACT CAATGGTCCA GGGCATAGCT CAAACAGAGC AACAGTAGCC 5100 CTGGGAAATG GAGGTGACAA AAGAAACAGA ATAAATCTTT CAAAATATAC TGCAATTTGT 5160 GCAACAGGAT GCCATATTGA TTTAAAAAAA TTTTTTTTCT TAAATTTTTT GTAGAGATGG 5220 GGGGAGGGGG TCTTGTTGTT GCCCAGGCTG GTCTTGAACT CTTGGTCTCA AGTGATCTTC 5280 TTGCCTTGGC CTCCCAAAAT GCTATGATTA TGTGCGTGAG CCACTGCTGC ATTGCGTTTT 5340 TTTTTCTTTT CTCGAGACGG AGTCTCACTC CGTCACCCAG GCTGAAGTGC ACTGGCGTGA 5400 TCTTGGTTCA CTGCAACGGC CTCCTGGTTC GAGCGATCCT CACACCTTAG CCTCCCTAGT 5460 AGCTGGAACT GCAGGCCTGG CTAAGTTTTG TATTTTTAGT AGAGACAGGG TTTCACTATG 5520 TTGGCCAGCC TGGTCTTGAA CTCCTGACCT CAGGTGATCA GCCTGCCTCA GCCTCCCAAA 5580 GTGCTGGGAT TATAGGTGTG AGCCACTGTG CCCAGCCTAC ATTGATATTT TTTAAAAGCC 5640 ACTATTTAAA AAGGAGTAAT CTGAGTAGTA AGAAGGAGTT CTTTAAAAAC TGGCCGGGCA 5700 TGGTGGCTCA CGCCTGTAAT CCCAACACTT TGGGAGGCCG AGGCAGGCAG ATCACCTGAG 5760 GTTGGTAGTT TAAGAGCAGC CTGACCAACA TAGAGAAACC CCATCTCTAC TAAAAATACA 5820 AAATTAGCCA GGTGTGGTGG CACATGCCTG TAATCCCAGC TACTCTGGGG GCTGAGGCAG 5880 GAGAATCGTT TGAACCTGGA AGGCAGAGGT TGCGGTGAAC CGAGATCGTG CCATTGCACA 5940 CCAGCTTGGG CAACAAGAGC AAAACTCCGT CTCAAAACAA AACAAAACAA AAATGAAAAC 6000 AAACAAAAAA ACACCAACAT GATTAGGAGG GAAAAAATCT AGATAGAAAG GCTTAACAGG 6060 GCCGGGCACG GTGGCTCATG CCTGTAAGCC CAACACTTTG GGAGGCCAGG GTGGGAGGAC 6120 TGCTTGAGGC CAGGAGTTTG AGACCAGCCT GGGCAACTTA GCGAGACTCT GGTAGTCTGT 6180 CTCTACCAAA CAAACAAACA AACACCTGAT TAGCTGGGCA TGGTGGCATA TGCCTATAGT 6240 CCCAGCTACC CGGGAGGCTG AGGCTGGAGG ATCGCTTGAG TCCCAGAGGT CAAGGCTGCA 6300 GTGAGCTGTG ATCAGGCCAC TGCACTCCAG CCTGGGCGAC AGAGCATGAG TCTGCCCCAG 6360 CCCTGCCTCC AAAAAAAGAA AGGCTAAATA GGAGAACTGA TATAACTGAA AACCAAATTA 6420 GTTGTGTGAA AGAGCAACTG TCCTGGAAGC TCCCAGAACA CAGAGCAATA AGAGATGAAA 6480 AATATGACAG CATAGAAAAG AAAGGAACTG GATAGGTCCA GGAGATCCAA TACCTGTGCA 6540 ACAGGAGAGT CCAAAGAAGA AACCAGTAAG AAGGGAGAGA AGTAATACAA GAAAGTTCCT 6600 GAGTTATCAG GCCAAAAGAA ATAATCTAGT TTGTGGAGTA ATATTGACAA AAAAATCTTT 6660 ACACCTAGAT GTATTCTGAA AAAATTCTTA AATTCTAATT GAAATCAACC AACGAACCAC 6720 AGGCCAGCCT TAGAAAACCA TTTCCAGGGC ATGGGGTTTT AGGGTCTGAC AGACCTGAAG 6780 TTCAAATTCC TACTATCCTA ACTTACTAGT AGTGTGATAA TCTCTTAGAA CAATGTATGA 6840 AATGGAAGCA TAATAGCACC CTCCACCTTT TAGAGTTAAT GGGAGATCTA AAAGAGGTAA 6900 CATTTGCAAA GTGTCTGACA TGAAGGGAAG AGATTGGCTT TGGCATCCAC AAGTTCACAC 6960 ACTAGCAGAG AACCTCAGTC CAGCTTCCTA CGCTCAGGCA GTTCTTTGCC TAGAAGAGGG 7020 GTCGGCAAAC TATAGCCCAA ATTTAGCCCA CTGCCTGTTT TTGTAAATAA AATGCTATCA 7080 GAACATGGCC ATGTTCATTC ATTTACATAC CATCTATGGC TGCTTTTACA TTACAAAGGC 7140 AGAGCTGAGT AGATGAGACA GAGACAGTAT GGTTACAAAC CGAAACTGTT TCAACCCCAA 7200 CTTCATTCCA GCAAAGTTTT ACTTTCTAGA TTCAGGCCAG GGAGCAAGCA TGAAAATGAA 7260 AACCACTAAA ATGGTGTCCC GGGACAACAG ATACCTACTT GCTATAACTT CTTTCCTTGA 7320 AAACAAAGGG CCATATTAAT TGAAGGGCTC ACCTCTAAAC AGGTGAGTGA CTTAAGGACT 7380 TCAGACACAC ACTGGTCAAC TACAAACTAG TCAGTAAAGG AATAGCCATA GTCCTATAGC 7440 CCCAGTTCCT ATGGCCCAGG GGGATCCACT AGTTCTAGAG CGGCCGCCAC CGCGGTGGAC 7500 TCCAG 7505 (2) INFORMATION FOR SEQ ID NO:14: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 529 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:14: GCTGAGGTGC ATCGCGGTGG CGGACGCTCT AGAACTAGTG GATCCCCAAA CAAAACCTGT 60 CCCTGCTAAT GATGGTAGAC CCAATCAGAT CCCCGGAGAA GCCGAAATAC GGAAACCATA 120 TCAGCATACG CATGGCATAC ATAGAACCCC ATACATGGAT TGCTTACTCA GCCAGATATA 180 GAAATCTATC TTCACGATAG AGATATATAT ATATAGACAC ACTGCATATA CAGATGTGAG 240 ATGGAGGCTC ACTCTGCCAC CCGTGCTGGA TCTACAGTGG CACAAGCTCA GTCCACAGTC 300 ACGTCGATCT GCCGGGCGTG ACCGACTGAG ATGCAGCGGC CTCGGGCGTA GCTGTGAGTA 360 CACGCACCAG TCATCGCGAC TGGCTGCAAG TGGTATAAGC GGAGGGGACA GGGTTACAGC 420 ATGACGGCTA GGCAGGCCGC AAACTGAGGA CCACAAGAGT GCCACGCTGC CCGAACGCAT 480 GCAGTGGCGA GATTACATGG GGCAGCCACT AGAGCCGCCG TATCAGAAA 529 (2) INFORMATION FOR SEQ ID NO:15: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 635 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:15: TACCACGCGG TAGCGCCGCT CTAGAACTAG TGGATCGGGT AATCCAGCAC TTTGGGAGGC 60 CAAGGAGGGC AGATCACCTG AAGTCAGGAG TTTGAGACCA GCCTGGCCAA CATGGTGAAA 120 CTCCATCTCT ACTAAAATTA CAAAAATTAG CCGGGCGTGG TGGCGCATGC CTGTAATCCC 180 AGCTACTCGA GAGGCTGCGG CATGACAGTC ACTCAAGCCC GGGAGGTAGA GGTTGCAGTG 240 AGCTGAGATT GTGCCACTGC ACTCCAGCCT GGGTGGCAGA GTGAGACCCT GTCTAAAAAA 300 AAA AAAAAA AAAGGCCCAT TAGGGGACCC AAACGGTTCC CCAGCTTTGT TGGATTTCCC 360 CAAATTTGGG GCCAATTTTT GGAGGGTTGT CCCTTAAAAA TTTAAATTTG GGGGTTTTTT 420 TCCAGGCGCC CATTAGAAAT GGGTTCCGAA AATTTTTTGG CCAAAAAAAT TTGGTTTAAC 480 CGCGGACCAA AATCCTAAGG TTTAACTTTT TCCTAAACCT TTTAGAATTT AAAGTTTCCG 540 GGGTTTCTCA GGAGGGGGTA ACCCTTCACC CCAATATAAC TCGGAAACCC CCCTTTTTTA 600 GGAAAAGGGG AATTAGTGGT GCTTTCCGGG CCAAA 635 (2) INFORMATION FOR SEQ ID NO:16: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 938 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:16: CCCAGGGACC AAGCGAGTGC GACCGCTCTA GAACTAGTGG ATCCCCCTTG AAGACTATAT 60 TTCTTTTCAT CACGTGCTAT AAAAATAATT ATAATTTAAA TTTTTTAATA TAAATATATA 120 AATTAAAAAT AGAAAGTAAA AAAAGAAATT AAAGAAAAA TAGTTTTTGG TTTCCGAAGA 180 TGTATAATAG GTTGAAAGTT AGAAATTATT ATTATAATAG CAAAAAAAAT TTAAAGTTAG 240 AAATTAGAAT TTAAGGCTCT ACACACGTTT ACGATGATAT TGGACGAACG ACACGATTAG 300 ACAGTTGTAG GTTGTGTGTT GTGATGTTTT TGAGTGATTT GTAGTGTTTA ACCTTGTGGT 360 TTGGAAAGGT NGTATGAGTA TTAATCTCGG GCTTATTGGG AGGTTTATGT GCAATGCATT 420 TTGTGGTTTT TTTATAATGT TGTGTTTAGG GTTAAAACCT GTTGTGTATA TTGTGTTGGT 480 TTGTTGCTTG TTTGTACATT GGTATGATGC CTNTTTTGCT TATGGGTTNG GTGTTTGGTT 540 TTGGTTGTGT TTTTTGTGGT GTGTTGTTTG ATAGTTTTAG CGGTTGTTTT TGGGTTGTTG 600 TTTTATGTTG TGGTGGTGTT TTGTGTGTAG AGTTGTGGTT TGTGTGTTTT GTTGGTTGTG 660 TTGTGGTATT GTTTATGTTT GTCGTGTGTA TGGTTTGTTG TTAGTCGTTG TTGTAGGCTT 720 GTGTGTTGTG TGTTGTGTGT GCGTGTGGTC TAGTTTGGGT GGTATTGTTG ATTTAGTGTG 780 ATAGTCTGTT AGAGTTTGGG TTGTTGTGTG TATTGGGTTT GTCTGTGTGT GGTTTTTTTG 840 TGGGTGTAGA TGATGATTTG TGTATGTGGG TGAGGTATAT GTTATTTGTG GTATTTCGGT 900 TGTGATGTGT TGGTTATTAT GTGTTTGTTA TGTGTATT 938 (2) INFORMATION FOR SEQ ID NO:17: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1145 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:17: GTCTCCGAGC TCACCGCGGT GGCGGCCGCT CTAGAACTAG TGGATCCCCC GCTCTCACTC 60 CCTGACTCTT GCCTTCTGTA ACAACTGGAG ACAACTCTTT CAAAACCAGC TCCAAGCCCC 120 AGACTTCTCT CTGGGCTTTA GTTCGTAAGG CAGGTGCCCT ACTGAGTGAG CCTAGATCAG 180 ACAGAAACAT AGCTGTTGGC AAGGATTTAG GTGAATTTCC TTCCATTGTT TTTCTAATAC 240 CTTTTTTTTT TTTTGGAAAA TATAACCATG CACCTACACA CATATTTGAA TATCCTGCCT 300 TTTTATTTAA AATGACATGA TAGGTCCGGG AGTGGTGGCT CATGCCTGTA ATCCCAGCAC 360 TTTGGGAGGC CGAGGTGGGC AGATCACCTG AGGTCAGGAG TTCGAGACCA GCCTGGCCAA 420 CATGGTGAAA CTCCATCTCT ACTAAAAATC AAAAATTAGC CGGGCATGGT GGCAGGCTCC 480 CAGCTACTCA GGAGGCTGAG ATGTGAAAAT CGCTTGAACC CGGGAGGTAG AGGTTGCAGT 540 GAGCTGAGAT CTTGCCATTG CACTCCAGCC TGGGCAATAA GAGCGAAACT CCATCTCAAA 600 A AAAAAAAA AAAACCCAGG GATAAACTTT CCAAAAGGCC CCAAAAAGGG GCATGATTAA 660 GACAATAAAT TAGTCGAAAA TTGTCAATAT AAATGAATAA TAATTTTTTT GGCCATTCTG 720 CCAAGTGGCA TAACCCTGTC ATTCTGCCCA TTCGGCAACT CTTTTTCCTC CCGGGGAATC 780 GCTCCCACTT TTTGCATGGG TTTTGGATGG AACTGTTGGT CACAGGTTTT TCACCCCCAT 840 TTGGCCCTCC CAGAGGTGTA CAAAGTACCC CAGCCTGGCC CTTTTTCACC CAATTTTCCC 900 AGGTATATTC CCCCGGTTTT GGTCCCAGGT TTTAACCCCC CCCTCCAAAG GGCTTTGGGT 960 TTTGGAAGGA TTAAGTCCTC GAAATAGGCC CCTCATAATA CCTGGGGGGG GGACCTTTTT 1020 CAAAGTTGTG GGCACCTCTT GTGTCGCCCC CACGGGGGAC TGATGTATTT ACGCCCCNTT 1080 GGGGNNTAAT ATGGATTGNT ATGTATTGGG CGAGGAGAAA ATATTTTTGA TGGGGTTTTT 1140 CTCTT 1145 (2) INFORMATION FOR SEQ ID NO:18: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 852 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:18: TCACCGCGGT GGCGGCCGCT CTAGAACTAG TGGATCCCCC GTTTTGCTCT CTCCTTAGAA 60 TGAGCTGGGA ACTAGTCACT CTTGTTTTCT CACCTATAAT AGCATCTGGG TCCAGTGTTT 120 TTTATGTGGG ACAAATTTGA ACTTGTGGTC AACCTCTTTA ATTGTAAGAA TATTCAGGTC 180 TTTTGTTCTT CCTGGGCTAG TTTTTTATTC TTTTTCTAGA GATTCGTTCA TTTTTCTTAG 240 TTTTATTTGC CTATAATTGT GGATAATCTG TTTTTTATCT GCTACTTCTG TAATTATTTC 300 CACATTTGAT TTATAATATT AACTTGTGGG CCAGGCGTCG TGGCTCACAC CTGTAATCCC 360 AGCACTTTGG GAGGCCGAGG CGGGCGGATC ACGAGGTCAA GAGATTGAGG TGAAACCCCC 420 TCTCTACTAA AAGTAGAAAA ATTAGCTGGG CATGGTGGTG CGTGCCTGTA ATCCCAGCTA 480 CTCAGGAGAC TGAGGCAGGG AATCTCTTGA ACCCAGGAGG CAGAGGTTGC GGTGAGCCAA 540 GATTGCACCA CGGCACTCCA GCCTGGTGAC AGAGCGAGAC TCCATCTCAA AAAAAGAAAA 600 AAAAAAAACT GTCAAATGAT ACTCCAAAAT GGTTGTACCA TTTTATATTT GCAACAACAA 660 TGTCTGAGGG TACTGATTGC TCCATATCCT TGACAGCACT TGGTATAGCC GATCCTTTAA 720 TTTTAGGCAC TTTAAGGGGG CAAATACCTG GGATTTTAAA GGTTTAACCT TTTTATTTTC 780 CCAAATGGGT TAATAGGTTC TCAGCAACTT TTCAAGGGGC CTAATTCCCC CCTTCAAAAT 840 AACCTCCCCT GG 852 (2) INFORMATION FOR SEQ ID NO:l9: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1854 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:19: CCGGCACTCA CCGCGGTGGC GGCCGCTCTA GAACTAGTGG ATCCCCGGAA ATGTTACTTC 60 CAACATTTTA GAACTGAAAT GATTCTTAGT CTGGTGATAA ATGTCAATTA AAATAGTTCT 120 CCTTTCACAG AGAAAATTAA GAAAAAATTA GTTCAAGAAA ATATCAATCA TGATTGCCAG 180 CGGAAATTTG TTTCTGCAGT AAAACAAGCA AAACAAATCA AATCCATTAA AACTAGCAAC 240 AGACTGTCTT CTAAAGTCAA GTTCACATCT GGAGATTTTT ATAAACTTTA TTGGAAAAGT 300 TCTGGTTATC TATATTTTTA GCATAGCAAA ATATTCTTCT TGTTTGTTGA ATTTGATATA 360 AAATGTTATT TTTAGCCAAG TCCTGGGGCA ACTCCTACAT GGCTGGAAAA TGTTCTCGGT 420 GTTAACAAAG ATGCAAAGAT CTTAAATATT AATGTTATCA ATCAACTGGA TACTCTTAAG 480 TATTATTTGT AATTATGTCC AATGTCATCA CCACAGGGCT GACCAACAAG CAAAGAGCTG 540 ACAGTAGTAG CAAAATGTAG AAATCTCTGG TAAGCATGTT GTGTTTATCA ATCCTCTTCA 600 AATAGATGAA ATTAAATTGC ATTTAAAGAA TGTTACTTAT ATTAGGCATT TTTTGTGAAA 660 GACGTTTTAA ACTATGGTGT CAGAAAACAG AAATACTAAA CAGAATGCAT TTAACAGGAC 720 CTTGAAATCA CTGAATACTC ACCTGTGTAA AAGTCAAAGT TCAGATAATT GAAATGTTCT 780 TACTAGTCTC AAGATGTCTT TTGGTTACAT AGAAATTTCC ATGCTGAATT TTGATTTTTT 840 TAAAAAGCCA TTAATATGAG TCAAAATCCA TTATTTCACA AGTAAATGAC CTTTTTATTA 900 AAAAAAAAAA AGAGAGAGAG AGAAGAGCAA GGAACCACCC ACATCTAACC TCTTAAATCT 960 GAGATCAATA TATCAAAATT TTAATGTACA TTGAAAACAT TTTCATTTTA TTCCACACAC 1020 TACCTTTTCT TCATAATTTC TTATTCTGGA CATATAGCAG TTTTTTTTGT CTTTTAAAAC 1080 AGGAAAAATA AACAAACATG GTCTTATTAT TGTTACTAAG TCACAGGTAG TAAAGATGGG 1140 ACCAGGAGAA CCTTGGAGGA CTAGAAACTT CTCAAGAGTA GTTAGATTTC ACATTCAGAG 1200 GGAGGACTCA GAGTCCTGCC TGGGACATAC ATTTGCATTC TAGGCTCAAG AGCAAATATG 1260 TCAGCTTTCC TTTGGTCAAA CAATCTTTGC TACAGGTCCT AGGTAGTTAT ATCAGTGGAA 1320 CCTACTAAAG ATGATGGAAT TTGTGGTATT TCAGGGTAGG AGGTAAAGTC TTAGCAGGCT 1380 CAACTATACA TGATCTTAAA ACTAAATTTG AAATGCAGAT GTTCTATGAG TTAGTTGGAT 1440 ATTGTAGTTA TCCCATCTAT CAACTGATCA CATTTGGTAT GAGCTTGTTA GTTCTGATTA 1500 GGACTCATCT CAACATAATA AGAAGGGTGG CATTTAGGGC CCAGTGTGGG GGCCTAGTGA 1560 TCACTGCTGG GACACTGCTT CTAAATCAAC ATAACTAACC TCTCTAGGAT GGCAGGCTGA 1620 GGCTGCTCAA GTACTTCCTG TCTGGCATCT GGGACAGGGC TGAGTCTCTG GGTGGGAAGA 1680 TGGGTGGGAG GACTGAGGCT GATGAGTATA TGATATAAAT GAGAGCCATT GGAATGGCTC 1740 CACATACAGG ACATGTTGAT AAATCATTTT AACATATTTT GCTTTCTCTC TCTGGTGGCC 1800 CATTGAGAAT CAAAAGGGGG ATCCACTAGT TCTAGAGCGG CCGCCACCGC GGTA 1854 (2) INFORMATION FOR SEQ ID NO:20: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 1101 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:20: CCACCTTTTC AATTCATCAT TTTTTTTTTA TTCTTTTTTT TGATTTCGGT TTCCTTGAAA 60 TTTTTTTGAT TCGGTAATCT CCGAACAGAA GGAAGAACGA AGGAAGGAGC ACAGACTTAG 120 ATTGGTATAT ATACGCATAT GTAGTGTTGA AGAAACATGA AATTGCCCAG TATTCTTAAC 180 CCAACTGCAC AGAACAAAAA CCTGCAGGAA ACGAAGATAA ATCATGTCGA AAGCTACATA 240 TAAGGAACGT GCTGCTACTC ATCCTAGTCC TGTTGCTGCC AAGCTATTTA ATATCATGCA 300 CGAAAAGCAA ACAAACTTGT GTGCTTCATT GGATGTTCGT ACCACCAAGG AATTACTGGA 360 GTTAGTTGAA GCATTAGGTC CCAAAATTTG TTTACTAAAA ACACATGTGG ATATCTTGAC 420 TGATTTTTCC ATGGAGGGCA CAGTTAAGCC GCTAAAGGCA TTATCCGCCA AGTACAATTT 480 TTTACTCTTC GAAGACAGAA AATTTGCTGA CATTGGTAAT ACAGTCAAAT TGCAGTACTC 540 TGCGGGTGTA TACAGAATAG CAGAATGGGC AGACATTACG AATGCACACG GTGTGGTGGG 600 CCCAGGTATT GTTAGCGGTT TGAAGCAGGC GGCAGAAGAA GTAACAAAGG AACCTAGAGG 660 CCTTTTGATG TTAGCAGAAT TGTCATGCAA GGGCTCCCTA TCTACTGGAG AATATACTAA 720 GGGTACTGTT GACATTGCGA AGAGCGACAA AGATTTTGTT ATCGGCTTTA TTGCTCAAAG 780 AGACATGGGT GGAAGAGATG AAGGTTACGA TTGGTTGATT ATGACACCCG GTGTGGGTTT 840 AGATGACAAG GGAGACGCAT TGGGTCAACA GTATAGAACC GTGGATGATG TGGTCTCTAC 900 AGGATCTGAC ATTATTATTG TTGGAAGAGG ACTATTTGCA AAGGGAAGGG ATGCTAAGGT 960 AGAGGGTGAA CGTTACAGAA AAGCAGGCTG GGAAGCATAT TTGAGAAGAT GCGGCCAGCA 1020 AAACTAAAAA ACTGTATTAT AAGTAAATGC ATGTATACTA AACTCACAAA TTAGAGCTTC 1080 AATTTAATTA TATCAGTTAT T 1101 (2) INFORMATION FOR SEQ ID NO:21: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 120 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:21: AACTAATGTA TCCCCCGGGC TGCAGGAACA CGATATAAAG CCTTAAAATT GTGCGAATGT 60 GRTAAGTCGA TCCAATCTCA ACTGCTATCT RTGTACCAGA ATAGTTTCAT AATTACGTGT 120 (2) INFORMATION FOR SEQ ID NO:22: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 300 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:22: GAATTCTCTG WKATTAKAAC TATCTTGMCT CAAATTSACT TGGTGAGCTA ACCTGGCCTG 60 TGGTCCCTTG GCTTTAATGG AGGCTTTGTC ATATAGATCA TMTGTGGTAC TKGTGCCTAG 120 TTGTAGTGCC CTGCCTTGCT STTCTWGGCT TACTKGATTT WGGGGTATAC ATCWATKTAA 180 YTSAAAGGTC TTTCTCCTCC CGYYGGGAGA ATTTCTCCTC CTCCCTCGGA GAACTCTTTC 240 TSCCGAAATT CTATTCCGGG CTGGGTCTCC ATTCTGCTTA CCTCCCACAC TTTTAATMAA 300 (2) INFORMATION FOR SEQ ID NO:23: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 599 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:23: GAATTCCCTC TTGCTTGGGG GAGGTCAGCC TTTTGTTCTA TTCAAATCTT TGAGGAAAAT 60 AGAAAGCAAA GAATATATTA ACTATATTAA ACAAACTAAA TGTTCCAATT AAAATACAAA 120 AATTATAAAG CCTAATAATA AAAGCCCTCA ATTATATGCT GTTTAAAAGA GACATTTTTA 180 AGCTTAAGGA TATAGAAAAG TTGAAAATAA AAGAATGGAA TAAAATAAGC CATGAAAATA 240 CTAGTATAAC ACTGATGTCA AAATCTGACA AAGCACACAA AAAAGAAAAT AACTTTAACT 300 GCAAAATCTT AAAATCCTAG CAAAGAAAAA GCAGCATATG TTATAATTAT ACCACAACCT 360 GATCAAGTAA GGCTTACTTC AAAAATTTAA CCATGGTCCA TTATTGGAAA ACATATTAAT 420 AAAAATCCTC ACAAAAATAA TTCAAAATAT AAAAAGCCAT ATGATAAGCC TGATGAATGC 480 TGGTTTACAG AACTGGTTTT CTTTAAAAAG GCAATCATTG GGGAAATAAC CCGCTTACTC 540 AGTATTTACT ATGTGCTAGC CCTGTTCCTT CTACTAGAAA TTAGTGAACA AATTCTAAC 599 (2) INFORMATION FOR SEQ ID NO:24: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 330 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:24: AAGCTTTCAA GAACAGGGAC TGTTAAGCCG GGTACAGTGG CTCACACCTA TAATCCTAGC 60 ATTTTGGGAG GCCAAGGCGG GTGGATCACT TGAGGTCAGG AGTTCAAGAC CAGCCTGGCC 120 <BR> <BR> <BR> <BR> <BR> <BR> AACATGGTGA AACCCCATCT CTACTAAAAA AAAAAAAAAA AAAGAAATWC AAAGAAATWC 180 MAAAATTACC CAGGCATGGT GGCACGCGCC TGTAATCCCA KCTACTTGGG AGGCTGAGGC 240 AGGAAAATTG CTTGAACCTA GGAGGCGGAG GTGGCAGTGA CCTAATCACA CCACTGTTCT 300 CCATCCTGGG CAACAGAACG AAACTGTTTC 330 (2) INFORMATION FOR SEQ ID NO:25: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 258 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:25: AAGCTTGGGT GATAATGAGG AGTCAATGTT GGTCCATCAA TTGCAACAAA GGTACCACAG 60 TGGTGTAGGA TGTGGATAAT GAGGAGGCTG TGCACGTGTT GGGGACAGGT GGTATTTACG 120 AATGCTCTAT ATTTTCTTTC TCTCTTTTTT TAGGACGGAG TCTCACTCTG TTGCCCACGC 180 TGGAATGCAY GGGCATGACT GTGGCTCACT GTACCCCCCA CTCCCCATGT TCAAGAGATT 240 CTCTTGCCTC ACCTCCTG 258 (2) INFORMATION FOR SEQ ID NO:26: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 622 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:26: CTCGAGTCCA CCGCGGTGGC GGCCGCTCTA GAACTAGTGG ATCCCCCGAT TTATTTAAAG 60 CAGTTATGTA TGTATGAAAA ACAATGCTGA GCATTCAATT CCAAGATTTC TGAAGACACC 120 TATTTTACCA TCACTTTGAA TAAAATTTTT ATATTCCTTT CTTCAAATAC CATCTCGGTT 180 TTCAAATGTG GCTCATTAAA TGTGAAAGCA AAATTTCATT TCAAATAGCA GCCTTATCAA 240 ATGACAATTT ACCTGTGGTA GCATTGTTGG CACTGACACA TATCAGACCA CTGCCGAGCA 300 GAACAAGAAT GAACCAGGAA TCCATGCTTA TCTGGAAAAT AGGGAGTCAT GTTAGATGAG 360 GTCCTATATT ATCAGGACTA TGTCTGAGCT GGTCACCAGA AGAGTATTCT GGATTTCCAA 420 GCTATTAAAA TGTGTGCCTA AACCAATGAT CTTTTGGGAG CCTGATATGC ATGCTTCCTC 480 AGATATCCAA TAACTAATTG AGTCTTTATA AAGACTGACT ATCCCTTATC TTGAGGACTA 540 GCAGTGTTTC AGATTTTTTT TAAGAGATAG GGTCTTGCTC TGTTGCCAGG ATGGAGACAG 600 TGGTTATGAT CATAGCTCAG TG 622 (2) INFORMATION FOR SEQ ID NO:27: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 602 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:27: TCGGACTCCA CCGCGGTGGC GGCCGCTCTA GAACTAGTGG ATCCCCCGGG CCCTCAGGAC 60 TGCTGGGCTG CCTGGTGTCA GCACTTCCCG CCATTTTCTA TAGCACCAGT ATTATTCTTA 120 ATACTTTAAA AAACCACCAG GCACGGTGGC TCACGCCTGG AATCCCAGCA CTTTGGGAGG 180 CCAAGGTGGG CGGATCACAA GGTCAGGAGA TCAAGACCAT CCTGGCTAAC ACGGTGAAAC 240 CCTGTCTGTA CTAAAAATAG AAAAAAATTA GCTGGGCGTG GTGGCATGCA CCTGTAGTCC 300 CAGCTGCTGG GGAGGCTGAG GCAGGAGAAT GGCGTGAACC CGGGAGGCGG ACTTGCAGTG 360 AGCCGAGATT GCACCACTGC ACTCCAGCCT GGGTGACAGA GCGAGACCCC GTCTCAAAAA 420 AAAAAAGTAA ATAAAAATAA AAAACCATAT CCCACTATCT CCCCCTTCTC TCTTTGCCTG 480 TGACTANNNG GCATACTTAT GGGGAAATCT TTAAGATGTC AGATTTCAGT TCTCTCACTT 540 TTCTACAACT TCTCCCCATT TTGCCTTTCT TAGGAACTTC CCTTCTTCCC ATCTGATTCC 600 TN 602 (2) INFORMATION FOR SEQ ID NO:28: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 546 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:28: TATCAAGGCG GAGTCCACGG TGGCGGCCGC TCTAGAACTA GTGGATCCCC GAACCAGGAA 60 TCCATGCTTA TCTGGAAAAT AGGGAGTCAT GTTAGATGAG GTCCTATATT ATCAGGACTA 120 TGTCTGAGCT GGTCACCAGA AGAGTATTCT GGATTTCCAA GCTATTAAAA TGTGTGCCTA 180 AACCAATGAT CTTTTGGGAG CCTGATATGC ATGCTTCCTC AGATATCCAA TAACTAATTG 240 AGTCTTTATA AAGACTGACT ATCCCTTATC TTGAGGACTA GCAGTGTTTC AGATTTTTTT 300 TAAGAGATAG GGTCTTGCTC TGTTGCCCAG GATGGAGACA GTGGTTATGA TCATAGCTCA 360 GTGCAGCCTC TACCTCCTGG ACTCAAGTGA TCCTTCTGTC TCAGCCTCCT GAGTAGCTGG 420 GACTATAGGC ATGTACTACG ATGCCTGGCT AATTTTTAAA ATTTTCTGTA GAGACGGCGT 480 CTCACTATGT TGTCTAGGCT GCTCTCAAAC TCTTGGGTTC AACTGATCTC TTGCTTCAAC 540 TTCCAG 546 (2) INFORMATION FOR SEQ ID NO:29: (i) SEQUENCE CHARACTERISTICS: (A) LENGTH: 498 base pairs (B) TYPE: nucleic acid (C) STRANDEDNESS: single (D) TOPOLOGY: linear (ii) MOLECULE TYPE: DNA (xi) SEQUENCE DESCRIPTION: SEQ ID NO:29: GTGGATTCAG ACGCGGTGGC GGCCGCTCTA GAACTAGTGG ATCCCCCGAG CAGAGGTTGC 60 AGTGAGCCAA GATCGTGCTA CTGTACTCCA GCCTGGGCAA CAGAGCAAGA CTCCGTCTCA 120 AAAAAAAAAA CAAACAAACG ATGTGTGCCT GTGTTTCCTC ATCTGTAGTA TGAGGATAAT 180 GATCATATAT ATTTACTAGT GTTGTTGGGA TGATCAAATT AGGTATATTT AATCATTGTG 240 TAAAAAAGTT GACGTGTAAA ATCCATGTAA AAAAGTTGGC AGAAGAGACA AACTGGTAAA 300 GCAGCCGTTC TTCATTTCTC ATTTCATTCA ACAAGCATTA TTAACAGCCT AGCAAGAACA 360 CAGTATCCAG GAAAAATCAA AGATTATCAA GCTCATGTTC TATAATCAAG CAATTTATAA 420 ACTAGCAGAA GAACAAGACA GATGAATAAG AACTTGGGTA TATTTAAATG CTAAGAAGTT 480 CAATTCAAAT AAATGTCC 498