NOVEL PHENYLALANINE DERIVATIVES

Title:

NOVEL PHENYLALANINE DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2002/028830

Kind Code:

A1

Abstract:

Specific phenylalanine derivatives or pharmaceutically acceptable salts thereof which have an effect of inhibiting $g(a)4 integrin and, therefore, are useful as remedies or preventives for inflammatory diseases wherein the $g(a)4 integrin-dependent adhesion process participates in the pathological conditions, for example, rheumatoid arthritis, inflammatory intestinal diseases, systemic lupus erythematosus, multiple sclerosis, Sjoegren's disease, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arteriosclerosis, restenosis, tumor proliferation, tumor metastasis and rejection in transplantation.

More Like This:

WO/2005/082874	NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS
JPS5812271	[Title of the Invention] 2- Oxo -4- Chicken Dithio -1- Azetidine Sakusan Louis No Seizohou
JP2002522493	INDUSTRIAL APPLICABILITY Pyrrolidine derivative for visual and memory impairment

Inventors:

SUZUKI NOBUYASU (JP)
YOSHIMURA TOSHIHIKO (JP)
IZAWA HIROYUKI (JP)
SAGI KAZUYUKI (JP)
MAKINO SHINGO (JP)
NAKANISHI EIJI (JP)
MURATA MASAHIRO (JP)
TSUJI TAKASHI (JP)

Application Number:

PCT/JP2001/008489

Publication Date:

April 11, 2002

Filing Date:

September 28, 2001

Export Citation:

Click for automatic bibliography generation Help

Assignee:

AJINOMOTO KK (JP)
SUZUKI NOBUYASU (JP)
YOSHIMURA TOSHIHIKO (JP)
IZAWA HIROYUKI (JP)
SAGI KAZUYUKI (JP)
MAKINO SHINGO (JP)
NAKANISHI EIJI (JP)
MURATA MASAHIRO (JP)
TSUJI TAKASHI (JP)

International Classes:

A61K31/395; A61K31/4015; A61K31/403; A61K31/4035; A61K31/435; A61K31/4355; A61K31/4365; A61K31/437; A61K31/438; A61K31/4412; A61K31/45; A61K31/472; A61K31/48; A61K31/4985; A61K31/55; A61P1/00; A61P3/10; A61P7/06; A61P9/00; A61P11/06; A61P19/02; A61P25/00; A61P29/00; A61P37/08; A61P43/00; C07D207/38; C07D207/452; C07D209/46; C07D209/48; C07D209/52; C07D209/66; C07D209/76; C07D211/88; C07D217/24; C07D217/26; C07D221/14; C07D221/20; C07D223/10; C07D223/18; C07D403/12; C07D471/04; C07D487/04; C07D495/04; C07D207/44; (IPC1-7): C07D207/448; C07D209/48; C07D209/52; C07D209/76; C07D223/18; C07D217/24; C07D211/88; C07D221/14; C07D403/12; C07D209/46; C07D471/04; C07D487/04; C07D209/66; C07D207/38; C07D211/86; C07D223/10; C07D225/06; C07D227/087; C07D495/04; C07D221/20; C07D491/14; C07D223/16; A61K31/4035; A61K31/55; A61K31/48; A61K31/4412; A61K31/472; A61K31/435; A61K31/4365; A61K31/4015; A61K31/437; A61K31/4985; A61K31/403; A61K31/45; A61K31/395; A61K31/438; A61K31/4355; A61P43/00; A61P29/00; A61P19/02; A61P1/00; A61P25/00; A61P11/06; A61P7/06; A61P37/08; A61P3/10; A61P9/00; A61P9/10; A61P9/08; A61P35/00; A61P35/04; A61P37/06

Domestic Patent References:

WO1999035163A1	1999-07-15
WO2000018759A1	2000-04-06

Other References: