Title:
NOVEL POLYENE MACROLIDE COMPOUNDS AND USES
Document Type and Number:
WIPO Patent Application WO1999064040
Kind Code:
A8
Abstract:
Novel multibinding compounds are disclosed. The compounds of the invention comprise 2-10 polyene macrolide antibiotic ligands covalently connected, each of said ligands being capable of binding to a ligand binding site in a cellular or viral membrane, thereby modulating the biological processes/functions thereof.
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Inventors:
GRIFFIN JOHN H (US)
JUDICE J KEVIN (US)
JUDICE J KEVIN (US)
Application Number:
PCT/US1999/012699
Publication Date:
July 26, 2001
Filing Date:
June 07, 1999
Export Citation:
Assignee:
ADVANCED MEDICINE INC (US)
GRIFFIN JOHN H (US)
JUDICE J KEVIN (US)
GRIFFIN JOHN H (US)
JUDICE J KEVIN (US)
International Classes:
A61K31/7048; A61K38/00; A61K39/00; A61K39/395; A61K39/44; A61K51/00; A61P31/10; C07H17/08; C07K2/00; C07K4/00; G01N33/53; G01N33/543; G01N33/566; (IPC1-7): A61K38/00; A61K39/00; A61K39/395; A61K39/44; A61K51/00; C07K2/00; C07K4/00; G01N33/53; G01N33/543; G01N33/566
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